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Re: Re Stopping the progression of MS

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oh! Good point there! LOL

I figure the two to compare is 3.0 and 4.5, that's all I've ever done. Nice to see people finding other doses better... could be frustrating though

[low dose naltrexone] Re Stopping the progression of MS

So far as I can see from our experience of LDN and reading others experiences the issue is setting the correct dose for the individual. My wife does well on 2.8MG but taking 4.5 made her much worse, worse than doing nothing. If you do not use the maximum dose that benefits you then you do run the risk of LDN not stopping MS progress, but if you go over the maximum dose that benefits you then you will do harm. Some can not cope with more than 1.5MG but those for whom that is the right dose they do fine, my wife started to get worse on 1.5Mg not as bad as 4.5Mg but 1.5Mg was not sufficient in her case to stop MS progress. A lot of debate has taken place on how to set the dose based on sex, height weight etc. and no rational method seems possible.

When you come across those that dismiss LDN as a placebo asking why the dose has to be so accurately defined before the placebo effect happens does seem to end the discussion.

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I suggest that the dose of LDN that is effective on a specific

person is a function of the other drugs and supplements being taken

by that person. IOW, every drug and supplement can interact with

each other; sometimes the effect can be negative. I have had

personal experience in this regard and it is an eye opener. The

problem is likely to be resolved by the " trial-and-error " approach.

Arnold

--- In low dose naltrexone , " LarryGC " <larrygc@s...>

wrote:

>

> oh! Good point there! LOL

>

> I figure the two to compare is 3.0 and 4.5, that's all I've ever

done. Nice to see people finding other doses better... could be

frustrating though

> [low dose naltrexone] Re Stopping the progression of MS

>

>

> So far as I can see from our experience of LDN and reading

others experiences the issue is setting the correct dose for the

individual. My wife does well on 2.8MG but taking 4.5 made her much

worse, worse than doing nothing. If you do not use the maximum dose

that benefits you then you do run the risk of LDN not stopping MS

progress, but if you go over the maximum dose that benefits you then

you will do harm. Some can not cope with more than 1.5MG but those

for whom that is the right dose they do fine, my wife started to get

worse on 1.5Mg not as bad as 4.5Mg but 1.5Mg was not sufficient in

her case to stop MS progress. A lot of debate has taken place on how

to set the dose based on sex, height weight etc. and no rational

method seems possible.

>

> When you come across those that dismiss LDN as a placebo asking

why the dose has to be so accurately defined before the placebo

effect happens does seem to end the discussion.

>

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I hope that the " overdose " MS progression is only tempory. My

husband was still getting worse on 4.5. We dropped the dosage to 3.0

just last week. We decided to get the compounders to give us 3.0

capsules and 1.5 capsules (instead of 4.5) just so we can experiment.

Does anyone know if the worsened symptoms are tempory?

PS. Thanks for the comment on the placebo--one more thing to ask--

Why is there increased leg stiffness at the beginning for so many

people if LDN is just a placebo?

Thanks.

Louise

--- In low dose naltrexone , " LarryGC " <larrygc@s...>

wrote:

>

> oh! Good point there! LOL

>

> I figure the two to compare is 3.0 and 4.5, that's all I've ever

done. Nice to see people finding other doses better... could be

frustrating though

> [low dose naltrexone] Re Stopping the progression of MS

>

>

> So far as I can see from our experience of LDN and reading others

experiences the issue is setting the correct dose for the individual.

My wife does well on 2.8MG but taking 4.5 made her much worse, worse

than doing nothing. If you do not use the maximum dose that benefits

you then you do run the risk of LDN not stopping MS progress, but if

you go over the maximum dose that benefits you then you will do harm.

Some can not cope with more than 1.5MG but those for whom that is the

right dose they do fine, my wife started to get worse on 1.5Mg not as

bad as 4.5Mg but 1.5Mg was not sufficient in her case to stop MS

progress. A lot of debate has taken place on how to set the dose

based on sex, height weight etc. and no rational method seems

possible.

>

> When you come across those that dismiss LDN as a placebo asking

why the dose has to be so accurately defined before the placebo

effect happens does seem to end the discussion.

>

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