Guest guest Posted October 21, 2005 Report Share Posted October 21, 2005 oh! Good point there! LOL I figure the two to compare is 3.0 and 4.5, that's all I've ever done. Nice to see people finding other doses better... could be frustrating though [low dose naltrexone] Re Stopping the progression of MS So far as I can see from our experience of LDN and reading others experiences the issue is setting the correct dose for the individual. My wife does well on 2.8MG but taking 4.5 made her much worse, worse than doing nothing. If you do not use the maximum dose that benefits you then you do run the risk of LDN not stopping MS progress, but if you go over the maximum dose that benefits you then you will do harm. Some can not cope with more than 1.5MG but those for whom that is the right dose they do fine, my wife started to get worse on 1.5Mg not as bad as 4.5Mg but 1.5Mg was not sufficient in her case to stop MS progress. A lot of debate has taken place on how to set the dose based on sex, height weight etc. and no rational method seems possible. When you come across those that dismiss LDN as a placebo asking why the dose has to be so accurately defined before the placebo effect happens does seem to end the discussion. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 21, 2005 Report Share Posted October 21, 2005 I suggest that the dose of LDN that is effective on a specific person is a function of the other drugs and supplements being taken by that person. IOW, every drug and supplement can interact with each other; sometimes the effect can be negative. I have had personal experience in this regard and it is an eye opener. The problem is likely to be resolved by the " trial-and-error " approach. Arnold --- In low dose naltrexone , " LarryGC " <larrygc@s...> wrote: > > oh! Good point there! LOL > > I figure the two to compare is 3.0 and 4.5, that's all I've ever done. Nice to see people finding other doses better... could be frustrating though > [low dose naltrexone] Re Stopping the progression of MS > > > So far as I can see from our experience of LDN and reading others experiences the issue is setting the correct dose for the individual. My wife does well on 2.8MG but taking 4.5 made her much worse, worse than doing nothing. If you do not use the maximum dose that benefits you then you do run the risk of LDN not stopping MS progress, but if you go over the maximum dose that benefits you then you will do harm. Some can not cope with more than 1.5MG but those for whom that is the right dose they do fine, my wife started to get worse on 1.5Mg not as bad as 4.5Mg but 1.5Mg was not sufficient in her case to stop MS progress. A lot of debate has taken place on how to set the dose based on sex, height weight etc. and no rational method seems possible. > > When you come across those that dismiss LDN as a placebo asking why the dose has to be so accurately defined before the placebo effect happens does seem to end the discussion. > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 23, 2005 Report Share Posted October 23, 2005 I hope that the " overdose " MS progression is only tempory. My husband was still getting worse on 4.5. We dropped the dosage to 3.0 just last week. We decided to get the compounders to give us 3.0 capsules and 1.5 capsules (instead of 4.5) just so we can experiment. Does anyone know if the worsened symptoms are tempory? PS. Thanks for the comment on the placebo--one more thing to ask-- Why is there increased leg stiffness at the beginning for so many people if LDN is just a placebo? Thanks. Louise --- In low dose naltrexone , " LarryGC " <larrygc@s...> wrote: > > oh! Good point there! LOL > > I figure the two to compare is 3.0 and 4.5, that's all I've ever done. Nice to see people finding other doses better... could be frustrating though > [low dose naltrexone] Re Stopping the progression of MS > > > So far as I can see from our experience of LDN and reading others experiences the issue is setting the correct dose for the individual. My wife does well on 2.8MG but taking 4.5 made her much worse, worse than doing nothing. If you do not use the maximum dose that benefits you then you do run the risk of LDN not stopping MS progress, but if you go over the maximum dose that benefits you then you will do harm. Some can not cope with more than 1.5MG but those for whom that is the right dose they do fine, my wife started to get worse on 1.5Mg not as bad as 4.5Mg but 1.5Mg was not sufficient in her case to stop MS progress. A lot of debate has taken place on how to set the dose based on sex, height weight etc. and no rational method seems possible. > > When you come across those that dismiss LDN as a placebo asking why the dose has to be so accurately defined before the placebo effect happens does seem to end the discussion. > Quote Link to comment Share on other sites More sharing options...
Recommended Posts
Join the conversation
You are posting as a guest. If you have an account, sign in now to post with your account.
Note: Your post will require moderator approval before it will be visible.