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RE: dl panthenol

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Angie,

dl-panthenol can be used in both hair and skin care. A little background

is in order. Panthenol comes in two stereo isomers. These isomers are

labeled either dextro or levo and are abbreviated with a d or an l.

d-Panthenol is biologically active while l-Panthenol is not.

Dl-Panthenol is only 50% biologically active. When you see the term dl-

in front of a compound name, that indicates that it is the racemic form

of that compound. It has approximately equal parts of the d- form and

the l- form. Stereo isomers are mirror images of each other and the

dextro and levo indicate the 'hand' of the isomer. Dextro means right

and levo means left. Other types of isomers in chemistry may have a 'D'

or 'S' designation. Again the 'D' is dextro for right and the 'S' is

sinister or left. In the early days left-handed people were thought to

be sinister. Today, we all know that if the left side of the brain

controls the right side of the body then only left-handed people are in

their 'right' mind. This is from a lefty. ;>)

Young

KY Labs

Innovators of Fine Personal Products

www.kylabs.com

dl panthenol

Hi All,

I'm looking for some good information on dl panthenol, rather than d

panthenol. I didn't see anything in the files and a search on google

didn't

turn up anything I found very helpful. I know the dl is primarily used

in

hair care, but don't understand why it could not be used in skin care.

I

have seen some formulas with it listed as an ingredient in

lotions/creams....so I assume it has been used. Any info is

appreciated.

Thanks, Angie

The Herbarie - Botanicals and Body Care

Natural Source & Specialty Bulk Ingredients...Exceptional Quality

at Wholesale Prices...visit us at http://www.theherbarie.com

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In a message dated 1/9/03 4:38:40 PM Pacific Standard Time, @...

writes:

> Angie,

>

> dl-panthenol can be used in both hair and skin care. A little background

> is in order. Panthenol comes in two stereo isomers. These isomers are

> labeled either dextro or levo and are abbreviated with a d or an l.

> d-Panthenol is biologically active while l-Panthenol is not.

> Dl-Panthenol is only 50% biologically active. When you see the term dl-

> in front of a compound name, that indicates that it is the racemic form

> of that compound. It has approximately equal parts of the d- form and

> the l- form. Stereo isomers are mirror images of each other and the

> dextro and levo indicate the 'hand' of the isomer. Dextro means right

> and levo means left. Other types of isomers in chemistry may have a 'D'

> or 'S' designation. Again the 'D' is dextro for right and the 'S' is

> sinister or left. In the early days left-handed people were thought to

> be sinister. Today, we all know that if the left side of the brain

> controls the right side of the body then only left-handed people are in

> their 'right' mind. This is from a lefty. ;>)

>

Hi ,

Thank you for the fascinating explanation! I am thinking we have at least

two chemist/philosophers on this list ;) The left/right thing does ring a

bell from way back somewhere? Am I correct to assume that the only

difference in functionality is that the dl is 50% active? I'm wondering why

we typically see dl used in hair care and d used in skin care...even though

as I mentioned I HAVE seen dl in skin care formulations, but not very often.

Angie

The Herbarie - Botanicals and Body Care

Natural Source & Specialty Bulk Ingredients...Exceptional Quality

at Wholesale Prices...visit us at http://www.theherbarie.com

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In a message dated 1/10/03 4:12:30 PM Pacific Standard Time, @...

writes:

> The d-Panthenol is 100% active and for your money you have more

> activity. d-Panthenol is a very thick liquid may be easier to

> incorporate into an emulsion than into a shampoo that is rinsed off

> anyway.

>

Thanks , that's good information. I have some samples of both on the

way and lots of good literature, so I'll be evaluating them. I really

appreciate your help.

Angie

The Herbarie - Botanicals and Body Care

Natural Source & Specialty Bulk Ingredients...Exceptional Quality

at Wholesale Prices...visit us at http://www.theherbarie.com

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Angie,

The d-Panthenol is 100% active and for your money you have more

activity. d-Panthenol is a very thick liquid may be easier to

incorporate into an emulsion than into a shampoo that is rinsed off

anyway.

Young

KY Labs

Innovators of Fine Personal Products

www.kylabs.com

Re: dl panthenol

In a message dated 1/9/03 4:38:40 PM Pacific Standard Time,

@...

writes:

> Angie,

>

> dl-panthenol can be used in both hair and skin care. A little

background

> is in order. Panthenol comes in two stereo isomers. These isomers are

> labeled either dextro or levo and are abbreviated with a d or an l.

> d-Panthenol is biologically active while l-Panthenol is not.

> Dl-Panthenol is only 50% biologically active. When you see the term

dl-

> in front of a compound name, that indicates that it is the racemic

form

> of that compound. It has approximately equal parts of the d- form and

> the l- form. Stereo isomers are mirror images of each other and the

> dextro and levo indicate the 'hand' of the isomer. Dextro means right

> and levo means left. Other types of isomers in chemistry may have a

'D'

> or 'S' designation. Again the 'D' is dextro for right and the 'S' is

> sinister or left. In the early days left-handed people were thought to

> be sinister. Today, we all know that if the left side of the brain

> controls the right side of the body then only left-handed people are

in

> their 'right' mind. This is from a lefty. ;>)

>

Hi ,

Thank you for the fascinating explanation! I am thinking we have at

least

two chemist/philosophers on this list ;) The left/right thing does ring

a

bell from way back somewhere? Am I correct to assume that the only

difference in functionality is that the dl is 50% active? I'm wondering

why

we typically see dl used in hair care and d used in skin care...even

though

as I mentioned I HAVE seen dl in skin care formulations, but not very

often.

Angie

The Herbarie - Botanicals and Body Care

Natural Source & Specialty Bulk Ingredients...Exceptional Quality

at Wholesale Prices...visit us at http://www.theherbarie.com

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Share on other sites

>d-Panthenol is a very thick liquid may be easier to

>incorporate into an emulsion than into a shampoo that is rinsed off

>anyway.

....and as I recall, d-Panthenol is a better humectant. I can't think

of a better reason to use Panthenol in a skin care product.

I haven't done this, but, I''ll bet that when you consider the cost to

benefit ratio, I think that you'll find other ingredients that are just

as effective as humectants that are less expensive.

Panthenol has consumer appeal on the label. " Now enriched the

Pro-Vitamin B-5 " .

Maurice

--------------------------------------------------------

Maurice O. Hevey

Convergent Cosmetics, Inc.

http://www.ConvergentCosmetics.com

-------------------------------------------------------

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Angie, I've been searching for more info links on Panthenol to put on

the site since I finally bought some more. Searching for DL-

Panthenol seems to only turn up manufacturers/suppliers and skin care

companies that list the ingredients listings. I did find some

articles about D-Panthenol on Medline. Here's links to the ones I've

read so far (if the link isn't active, just cut and paste):

*Topical use of dexpanthenol in skin disorders.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?

cmd=Retrieve & db=PubMed & list_uids=12113650 & dopt=Abstract

*Effect of topically applied dexpanthenol on epidermal barrier

function and stratum corneum hydration. Results of a human in vivo

study.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?

cmd=Retrieve & db=PubMed & list_uids=10965426 & dopt=Abstract

*Improving wound healing after nose surgery by combined

administration of xylometazoline and dexpanthenol

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?

cmd=Retrieve & db=PubMed & list_uids=10763172 & dopt=Abstract

It looks like there are lots more articles, but I haven't had time to

get to the others.

This one doesn't have to do with panthenol, but it came up on my

search and I thought it might be interesting:

*Factors defining sensitive skin and its treatment.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?

cmd=Retrieve & db=PubMed & list_uids=9744910 & dopt=Abstract

> In a message dated 1/9/03 4:38:40 PM Pacific Standard Time,

@k...

> writes:> > Dl-Panthenol is only 50% biologically active.

, could you explain to me what the l-panthenol is for? When you

say it's not active, does that mean it's basically a filler or

extender for the d-panthenol? Is dl-panthenol is just an

inexpensive, but less beneficial, way of having the label appeal

of " Contains Pro-Vitamin B5 " ?

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