LDN & Pain Management

[Guest guest]

I have a few questions regarding LDN & Pain Management that I think

are important & was hoping to get some feedback on. Since LDN is said

to raise endorphins {from: endo(genous) + (mo)rphin(e)} by a mechanism

of a temporary few hour block of opiate receptors causing the body to

produce 200-300% more endorphins the following day:

1) When you dose the LDN between 9 PM - 3 AM as recommended do you

notice a difference in pain sensitivity while LDN temporarily blocks

opiate receptors (for those who are opioid drug free of course)?

2) Does LDN only cause the 200-300% endorphin increase for those with

low endorphin levels or everyone?

3) Could those who complain of morphine-like side effects such as

constipation (or other side effects) have higher than normal levels of

endorphins after LDN & are chronically higher than normal levels of

endorphins otherwise problematic?

4) Since endorphins reduce the sensation of pain, do you feel LDN

increasing your endorphins reduces your sensation of pain (that is

before an improvement of autoimmune or other disorder that causes pain

symptomatology or only after)?

5) If LDN stabilized your underlying condition that caused chronic

pain syndromes, have you found the ability to reduce or eliminate

other pain drugs?

6) If you had to have a surgical procedure where opioids were

recommended mainly for nociceptive pain control (vs. chronic

neuropathic pain that utilizes many other analgesics) do you insist on

non-opioid pain medications (e.g. NSAIDs, ketamine) or take a break

from or reduce the naltrexone to ULDN 0.5 mg temporarily as dosed in

Pain Therapeutics trials?

Thanks for your feedback ( & sorry if my posts feel like

homework:)-reply to any you are able to,

Best Wishes, Josh