Re: Generic LDN-vs-Duramed-vs-DuPont

[Guest guest]

Hi again, question still stands but the instructions for liquid LDN at

http://goodshape.net/HomemadeLDN.html (not sure how updated this page

is) lists:

" The best source of Naltrexone, in order to prepare Homemade LDN

doses, is the 50mg " ReVia " Naltrexone tablet made by DuPont " which I

found below at Walgreens " Drug Manufacturer: DUPONT PHARMA " including

photo:

http://www.walgreens.com/library/finddrug/druginfo1.jsp?particularDrug=Revia & id=\

12749

Walgreens price appears better than CVS/even drugstore.com but is a

longer trip if picked up. When local Walgreens was called they said

they didn't have any in stock but if it were ordered it is listed as

Dupont but couldn't confirm until it was received...(also not sure how

current that Walgreens page is)

I'm left wondering how many companies make brand name ReVia in the US

& the differences among these various brands & generics?

Thanks, Josh

> > > Hi, I just wanted to comment on a post a while ago about generic

> > > (Barr) vs. Brystol Myers LDN. I had the same problem as Rhonda

> > had.

> > >

[Guest guest]

I called Walgreens and they said they can't tell us if will be Dupont

when they order. I say NO b/c Dupont doesn't make Revia anymore nor

Bristol Myers in US. I called Bristol Myers last week and they

referred me to Barr which I had already talked to. Duramed is name

brand Revia in US and Barr Lab makes the Generic. I haven't yet

tried the Duramed I have b/c of going downhill on the Generic. I

haven't seen anyone else post that they are using the Duramed Revia

to know if it works. I got parnoid that it would be the same as the

Generic since Duramed is a Subsidiary of Barr Lab which makes the

Generic. I ordered some more Bristol Myers from www.medsmex.com and

plan to order more just to know I have more on hand. Also, I got an

email from medsmex b/c I had ordered from them before, that if I

refer someone to them that they get a $10 discount and I get a $25

discount so that helps me save some. I referred a member here. Just

wish I could have ordered two at once and saved on the shipping.

The liquid instructions are correct on www.goodshape.net. I have

used bottled water and haven't tried distilled yet but I will just to

see if better. Also, there are oral syringes that work great for

measuring the 50mls of water and the one I have is a 10ml and has a

snap on top if you ever need to carry your meds out with you. I put

on blue ice to keep it cold til I take. I also have a 5ml dropper

with the bulb end which draws up the liquid meds quick after you

shake the jar. I use a 2oz pimento jar that has a screw on lid which

works good to keep the liquid meds in. Remember to keep in the

fridge.

Rhonda

> Hi again, question still stands but the instructions for liquid LDN

at

> http://goodshape.net/HomemadeLDN.html (not sure how updated this

page

> is) lists:

>

> " The best source of Naltrexone, in order to prepare Homemade LDN

> doses, is the 50mg " ReVia " Naltrexone tablet made by DuPont " which I

> found below at Walgreens " Drug Manufacturer: DUPONT PHARMA "

including

>

[Guest guest]

Hi Rhonda/everyone, does anyone know when Dupont & Bristol Myers

stopped making ReVia for the US market?

I too wonder if Duramed's Revia & Barr's generic naltrexone are just

the same formula-as you mentioned I read Duramed is now a Barr subsidiary.

I'm a bit concerned about what I would get from any country/region

besides US, Canada, Europe. Don't get me wrong, I'm glad medsmex.com

is there for people but I simply wonder if their products can be

consistently counted on.

Certainly there must be people using Duramed's ReVia & perhaps don't

know it...

Best Wishes, Josh

> > Hi again, question still stands but the instructions for liquid LDN

> at

> > http://goodshape.net/HomemadeLDN.html (not sure how updated this

> page

> > is) lists:

> >

> > " The best source of Naltrexone, in order to prepare Homemade LDN

> > doses, is the 50mg " ReVia " Naltrexone tablet made by DuPont " which I

> > found below at Walgreens " Drug Manufacturer: DUPONT PHARMA "

> including

> >

[Guest guest]

Someone posted here when DuPont and Bristol sold rights but I can't

remember. You can go back and read some post and see if you find

it. Barr claims Bioequivalent but I'm here to tell you the Generic

is NOT which makes me think the Duramed is the same pill with Revia

stamped on it but I could be wrong since made in another lab. I just

couldn't risk it at the point I got to on the generic. All you can

do is try the Duramed and see and I think medsmex is def. OK and it's

made by Bristol Myers Squib so should be consistant. There is a site

in Canada that showed a pill on site and said Dupont but the pic of

pill is no longer there so may be Duramed now. You need a script for

Canada. http://www.abconlinepharmacy.com/ns/customer/product1581-c-

p1

> Hi Rhonda/everyone, does anyone know when Dupont & Bristol Myers

> stopped making ReVia for the US market?

>

> I too wonder if Duramed's Revia & Barr's generic naltrexone are just

> the same formula-as you mentioned I read Duramed is now a Barr

subsidiary.

>

>

[Guest guest]

I assume the problem with generics here are mainly the issues of:

1) Does Average Bioequivalence Equal Therapeutic Equivalence?

2) Narrow Therapeutic Index Drugs

These issues are covered at length at:

http://www.ama-assn.org/ama/pub/category/15279.html

LDN would appear to have a rather narrow therapeutic index hence the

concern with getting the correct dose.

I may just order from Irmat Pharmacy but I wanted to first be able to

experiment with dose very easily (not to mention making your own

liquid LDN is less expensive).

Interesting that when I listened to the 2005 conference at:

http://www.low dose naltrexone.org/events.htm they mentioned that if LDN

were FDA approved it would likely cost exponentially more & that it

would no longer be legal for pharmacies to compound it.

However they did not mention that the 50 mg dose would still be sold &

people could of course still compound their own at enormous savings.

Anyone out there have experience with Duramed's ReVia liquid LDN?

Comments?

Thanks, Josh

[Guest guest]

Thanks Rhonda, this looks like it:

low dose naltrexone/message/28384

Assuming that timeline is correct Barr Labs gained the rights to ReVia

brand name in April 2002 so people have likely been using it.

Did you happen to try adjusting the dose at all on that non ReVia

generic naltrexone?

In any case I hope this sorts itself out and you get better again.

Have you considered just ordering from Irmat Pharmacy since they've

been compounding it the longest?

Issues brought up in my last post still stand (to ponder for those not

in a current jam):

low dose naltrexone/message/28644

Best Wishes, Josh

> Someone posted here when DuPont and Bristol sold rights but I can't

> remember. You can go back and read some post and see if you find

> it. Barr claims Bioequivalent but I'm here to tell you the Generic

> is NOT which makes me think the Duramed is the same pill with Revia

> stamped on it but I could be wrong since made in another lab. I just

> couldn't risk it at the point I got to on the generic. All you can

> do is try the Duramed and see and I think medsmex is def. OK and it's

> made by Bristol Myers Squib so should be consistant. There is a site

> in Canada that showed a pill on site and said Dupont but the pic of

> pill is no longer there so may be Duramed now. You need a script for

> Canada. http://www.abconlinepharmacy.com/ns/customer/product1581-c-

> p1

[Guest guest]

>No, I didn't think at the time to try more than 4.5mgs but did noticed

first 10 days something wasn't the same and I mixed up some BM Revia

and then it fell out of fridge and I lost 10 days of that and only had

a few BM Revia left so tried another batch of generic just to go down

hill from there and realized it wasn't working. Didn't think at the

time that maybe the 4.5mgs wasn't actually 4.5mgs. In the future, if I

get Brave, may try the Duramed but really scared to mess with the

generic even if I increase dose.

Rhonda

> Did you happen to try adjusting the dose at all on that non ReVia

> generic naltrexone?

>

>