Guest guest Posted August 17, 2005 Report Share Posted August 17, 2005 i have been on 3 mgs since march. at first LDN was really working like gangbusters, as far as symptom relief and there was no progression and my MRI's were stable. lately, there has been some real activity noticed by me and by my physical therapist. mostly losing my sight and getting fatigued much faster and easier. i have tried to go up to 4.5 mgs, but my body did not like it at all. i now have smaller increments to raise the dose with. my question is: has anyone else noticed a dramatic improvment and then a gradual decline as i have. thank you, joanna PS- i am primary progressive and have tried everything else, so this drug is really my last option.-j Quote Link to comment Share on other sites More sharing options...
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