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Referat fra Prof. De Meirleir

og Dr s XMRV-foredrag

i Madrid 26.05

Rutt @ 14:50

*Yesterday we have gone to Madrid to hear Dr. Dan

's lecture.

It was an all morning session about XMRV, and the

first to talk was Dr. Dan . He shared with

everybody some of the findings in XMRV (nothing

new) with many references to Dr. Judy Mikovits and

the WPI, and his slides were the same that Dr.

Mikovits uses in her lectures. The reasons for leaving

the WPI were more a personal decision in order to

have more time for himself after 25 years of service

in WPI. He seems to be having a nice rest and is

very happy to have the time to go sailing again.

At some point It was mentioned by ,

that so far the best biomarker for CFS is the Low

NKCell function test, and that if your budget was

restricted, this would be the test to do, I guess He

was referring to the same direction than Dr. Klimas

is always talking about as well. http://bit.ly/cJ7YVc

The second lecture was from Dr. Kenny De Meirleir,

very interesting, focused on the fact that the most

important thing now is to have a simple and good

XMRV Test for all the researchers. He assured that

they already have the test and it works, and it is a

matter of days that they will make it available, 3 to

4 weeks probably.

De Meirleir also talked about all the work that is

being done and possible treatments, but curiously

never mentioned the Ampligen. Dr. Marc Fremont's

lecture was very technical about this test, and

finally, Dr. Roelant talked about the urine test

they already have, which indicates intestinal

dysbiosis is present in these patients.

Some of the questions posted in the Conference

were regarding the recent German study, and the

fact that XMRV is 3 times more present in immune

compromised patients already tells you that there is

an immune problem on CFS patients where most of

them have the retrovirus.

There are three pathways affected on CFS which

affect muscles and CNS:

25-A

PKR

NO

There are also 3 pats of the immune system

affected:

Th1 Linked to viral reactivation and intracellular

infection due to an excessive hypersensitivity

Th2 Linked to pathogens, allergies and inflammation

and blood brain barrier dysfunction

Th17 Linked to autoimmunity and inflammation and

blood brain barrier dysfunction

De Meirleir elaborated later on that Th2 imbalance

that causes diseases such as CFS, Autism, HIV, MCS,

Mercury exposure, Allergies, Parasites.

Th1 relates to cell-based immunity Th2 relates to

Humoral immunity

You can see a bit on the conference in this link:

http://www.youtube.com/watch?v=ywLnptBQLeg

When we asked to comment on Dr.

Hubert lecture of last Monday in London, his answer

was that Huber had positives 17 of the 19 samples

that were sent to her, but She only spoke of the

samples of other doctors who have tested negative.

has said that once again we face the

uncertainty of correctness in the samples tested, but

also added that if She would have done a good job,

She could not have all negatives, at least 3% would

be positive, as we see is happening with the recent

German study.

When we asked about the fact that HIV patients that

are XMRV positive and have CFS, are not reacting to

their current antiretroviral treatment, and that could

lead to the possibility that XMRV is just a passenger

virus in a depressed immune system, his answer was

that actually that would be one possibility, and the

other one is that they are taking the wrong drug,

because XMRV is a different retrovirus, and they are

being treated for HIV.

When we asked about the German study, and the

fact that XMRV has been found now in the respiratory

tract, and that could lead to new ways to detect

XMRV different from the ones used in WPI, He said

that is a big possibility. As we know blood is not the

reservoir of XMRV, maybe the brain or the liver…

There were some other questions regarding the

prevalence of CFS in children, banning blood

donations, etc…

I will try to add the whole Conference next week if I

have the time to do so, but basically these would be

the headlines of the Conference.*

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