For Eileen ... Celiac Disease

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> 1: Plast Reconstr Surg. 1996 Jun;97(7):1427-33; discussion 1434-

5.Related Articles, Links

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> Capsular synovial metaplasia as a common response to both textured

and smooth implants.

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> Ko CY, Ahn CY, Ko J, Chopra W, Shaw WW.

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> Division of Plastic and Reconstructive Surgery, UCLA School of

Medicine, Los Angeles, Calif, USA.

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> Recent reports suggested that the presence of synovial metaplasia

in the capsular tissues of breast implants is greater with textured-

shelled implants compared with smooth. Textured implants, however,

have become popular only in the last few years. Therefore, the

studies do not address the possibility that synovial metaplasia may

be a dynamic process related to time (e.g., implant age) rather than

implant shell surface. In the current study, 159 implant capsules

(85 patients) removed between February of 1992 and July of 1993 at

UCLA Medical Center were evaluated histologically and correlated

with clinical data, including the age of implants. Synovial

metaplasia was identified in 40 percent (64 of 159) of the capsule

specimens. A logistic regression analysis that removed the effect of

implant age demonstrated no correlation of implant shell type

(textured versus smooth) with the presence of synovial metaplasia.

Gel bleed, implant location, pericapsular fluid, implant rupture,

and capsular contracture also did not have any significant

association with synovial metaplasia in the current study. The

incidence of synovial metaplasia appears to decrease with age (77

percent at < 5 years; 22 percent at > 15 years). Our findings

suggest that synovial metaplasia is not rare and in fact may be a

fairly common transitional histologic finding. It may be part of the

common progression that occurs at the implant-capsule interface. The

clinical significance remains unknown.

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> PMID: 8643727 [PubMed - indexed for MEDLINE]

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> Eileen Swanson

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