A word of caution for us all

February 23, 2005

Dear Group,

I'm the first one to look for a bargain. But I want to add a word of

caution about using various untried topicals for PG. Jeff has told us

that PG can " spread like wildfire " when treated incorrectly. Even when

treating it properly it is sometimes not responsive :-( So please be

careful!

Also Ian you have sent in info on " erythema induratum " whch is not the

same as erythema nodosum. EI seems to be caused by a cutaneous TB, at

least half the time. Although EN can be caused by TB, this has not

been found to be a very common trigger in this group. In fact I know

of no one who ever tested positive for TB in our group so far.

Here is a link comparing EI and EN:

224259 & Ausgabe=226206 & ArtikelNr=26058

and a link that addresses subcutaneous TB specifically:

There are many forms of panniculitis. Panniculitis only means

inflammation of the fat cells.

Here is a a good link that breaks down the many forms of panniculitis

and their similarities and differences:

So while we may find that some treatments may help both EI and EN,

others may not as the apparent trigger may be different.

Remember, EN does NOT ulcerate as a general rule:

<<erythema induratum

This is a now rare condition of unknown origin, formerly thought to be

a reaction to the tubercle bacillus. Principally, young women are

affected. Presentation is with a symmetrical eruption of painful

ulcerating nodules on the posterior aspect of the lower legs. The

patient is often obese. Treatment is difficult. Weight reduction and

avoidance of low temperature environments may be of benefit.>>

I think it is great to " look outside the box " and I feel that doing so

will yeild useful info and possibly be the key to finding a cure, but

just be aware that it may also confuse an already complex issue.

Love,

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