Guest guest Posted November 30, 2005 Report Share Posted November 30, 2005 Dear Maggie, I just reviewed your " Case History " on our Member Medical History Files [They really ARE useful, and to other members who have not submitted them yet, please do]. First off, I too often get the " red patch " that developes from a single oblong shaped lump. In my case it goes from above the ankle to the middle of the calf, but only on the inside of the leg. I only have EN on my left leg. I too am 58. I have read that the patch is more common with older patients. I don't know exactly why, but I think it may have something to do with greater difficulty of our body to pump out the edema. I use a TEDS anti-embolism stocking, but a wrap around elastic bandage like the ACE would work just as well, and you can vary the pressure more to your liking with a bandage. Are you still working those 11 hr. days? It is my belief from personal experience and what I've read that lack of rest will make the EN take longer to resolve. If anyone was a candidate for SSKI it's you, as you really need to get over this if you need to be on your feet so much. If SSKI will help, it won't take long to know. And if it doesn't work in a couple weeks, it probably won't, so you can stop it. I'm concerned about the underlying cause with you as you stated " I have an IGM, GTT and SED RATE that are five times normal, with only one other " symptom. " About once a day my whole body gets hot and begins to itch. " As you know, the itch point us to the liver for further investigation. Hepititis is a cause of EN, and I imagine that has been ruled out. The IgM is an " inaccurate " test for herpes from what I've read. Herpes is, by the way, another cause of EN. So keep looking for the cause as I think there are quite a few avenues to explore to get to the bottom of the EN outbreak. These are simply some preliminary ideas from my limited knowledge of medicine and surfing the web. I do feel you will, with a competant doctor uncover the problem. You might want to show the doctor our list of triggers and causes of EN. Here it is: ****** Etiologic factors in erythema nodosum From: http://dermatology.cdlib.org/DOJvol8num1/reviews/enodosum/requena.html http://dermatology.cdlib.org/DOJvol8num1/reviews/enodosum/table1.html 1. Infections * Bacterial infections: *Atypical mycobacterial infections27 *Borrelia burgdorferi *infections28 Boutonneuse fever29 *Brucellosis30 *Campylobacter infections31 *Cat-scratch disease32 *Chancroid27 *Chlamydia psittaci infections33 *Corynebacterium diphteriae infections27 *Dental Infections *Escherichia coli infections10 *Gonorrhea34 *Leptospirosis35 *Lymphogranuloma venereum36 *Meningococcemia37 *Moraxella catarrhalis infections38 *Mycoplasma pneumonia infections39 *Pasteurella pseudotuberculosis infections40 *Propionibacterium acnes 41 *Pseudomona aeruginosa infections42 *Q fever43 *Salmonella infections44 *Shigella infections45 *Streptococcal infections46 *Syphilis47 *Tuberculosis48 *Tularemia49 *Yersinia infections50 * Viral infections: * Cytomegalovirus infections51 * Hepatitis B52 * Hepatitis C53 * Herpes simplex27 * HIV infection54 * Infectious mononucleosis55 * Measles56 * Milker's nodules57 * Orf56 * Parvovirus B19 infections58 * Varicella59 * Fungal infections: * Aspergillosis60 * Blastomycosis61 *Coccidioidomycosis62 aka Valley Fever http://www.emedicine.com/med/topic539.htm * Dermatophytes63 * Histoplasmosis64 * Sporotrichosis27 * Protozoal infections: Amebiasis65 * Ancylostomiasis27 * Ascariasis66 * Giardiasis65 * Hydatidosis67 * Hookworm infestation27 * Sparganum *larva68 *Toxoplasmosis69 * Trichomoniasis70 2.- Drugs * Acetaminophen71 * Actinomycin-D71 * All-trans retinoic acid72 * Aminopyrine27 * Amiodarone71 * Amoxicillin10 * Ampicillin10 * Antimony27 * Arsphenamine34 * Azathioprine71 * Bromides73 * Busulfan71 * Carbamazepine71 * Carbenicillin71 * Cefdinir71 * Chlordiazepoxide71 * Chlorotrianisene71 * Chlorpropamide71 * Ciprofloxacin71 * Clomiphene71 * Codeine71 *Cotrimoxazole71 *Cytokine Therapy * D-penicillamine74 * Dapsone71 * DES * Diclofenac71 * Dicloxacillin71 * Diethylstilbestrol71 * Disopyramide71 * Echinacea herbal therapy75 * Enoxacin71 * Erythromycin10 * Estrogens71 * Fluoxetine71 * Furosemide71 * Glucagon71 * Gold salts76 *Granulocyte colony-stimulating factor71 *Halogens * Hepatitis B vaccine77 * Hydralazine71 *Ibuprofen71 *Imatinab * Indomethacin71 * Interleukin-278 * Iodides73 * Isotretinoin79 * Leukotriene modifying agents (zileuton and rafirlukast)80 * Levofloxacin71 * Meclofenamate71 * Medroxyprogesterone71 * Meprobamate71 * Mesalamine71 * Methicillin71 * Methimazole71 * Methyldopa71 * Mezlozillin71 * Minocycline81 * Naproxen71 * Nifedipine71 * Nitrofurantoin27 * Ofloxacin71 * Omeprazole82 * Oral contraceptives83 * Oxacillin71 * Paroxetine71 * Penicillin77 * Phenylbutazone60 * Phenytoin57 * Piperacillin71 * Progestins71 * Propylthiouracil84 * Pyritinol34 * Sparfloxacin71 * Streptomycin71 * Sulfamethoxazole71 * Sulfixoxazole71 * Sulfonamides85 *Sulfosalazine71 *Tetracycline * Thalidomide86 * Ticarcilin71 * Trimethoprim87 * Typhoid vaccination88 * Verapamil71 3. Malignant diseases * Adenocarcinoma of the colon89 * Carcinoma of the uterine cervix90 * Hodgkin's disease91 * Leukemia92 * Non-Hodgkin's lymphoma93 * Pancreatic carcinoma94 * Post-radiotherapy for pelvic carcinoma8 * Renal carcinoma78 * Sarcoma34 * Stomach cancer10 4. Miscellaneous conditions * Acne fulminans95 * Adul Still's disease96 * Ankylosing spondylitis97 * Antiphospolipid antibodies syndrome98 * Behçet's syndrome99 * Berger's disease100 * Chronic active hepatitis101 * Celiac disease102 * Colon diverticulosis34 *Crohn's disease103 *Dental infection * Diverticulitis104 *Granulomatous mastitis105 *Hedgehog zoonoses http://www.findarticles.com/p/articles/mi_m0GVK/is_1_11/ai_n8966491 * IgA nephropathy106 * Jellyfish sting107 * Lupus erythematosus108 * Pregnancy109 * Radiotherapy110 * Recurrent polychondritis111 * Reiter's syndrome112 * Rheumatoid arthritis113 * Sarcoidosis114 * Sjögren's syndrome115 * Smoke inhalation in a house fire116 * Sweet's syndrome117 * Systemic lupus erythematosus-like syndrome due to C4 deficiency118 * Takayasu's arteritis119 * Ulcerative colitis120 * Vogt-Koyanagi disease115 * Wegener's granulomatosis121 ***** Love, Quote Link to comment Share on other sites More sharing options...
Guest guest Posted November 30, 2005 Report Share Posted November 30, 2005 , thank you for this informative post! Having had Lyme’s Disease more than once and since I have been an outdoorsy person since I was a child, I have always credited the ticks with giving me my EN. (heh heh, I blame them for everything.) But after each bout in the last 10 yrs, I have noticed the lumps in my upper thigh have got worse for a while, along with those lymph node pains, depending on where the little buggers had chomped in for a meal. Then today, I read in this post the list of bacterial infections that can cause EN and there they are, Borrelia burgdoreri, my little Lyme’s bacteria. Odd, it is comforting somehow to know that they again are culprits in my various ill health issues. As I read many of the posts, I wonder how many of these people here have been bitten by the ticks as some of their symptoms are classic text book symptoms of Lyme’s or Stari. Thanks for all the good work you do for us all. Barb and all the fuzzy ones Re: Msg for Maggie Dear Maggie, I just reviewed your " Case History " on our Member Medical History Files [They really ARE useful, and to other members who have not submitted them yet, please do]. First off, I too often get the " red patch " that developes from a single oblong shaped lump. In my case it goes from above the ankle to the middle of the calf, but only on the inside of the leg. I only have EN on my left leg. I too am 58. I have read that the patch is more common with older patients. I don't know exactly why, but I think it may have something to do with greater difficulty of our body to pump out the edema. I use a TEDS anti-embolism stocking, but a wrap around elastic bandage like the ACE would work just as well, and you can vary the pressure more to your liking with a bandage. Are you still working those 11 hr. days? It is my belief from personal experience and what I've read that lack of rest will make the EN take longer to resolve. If anyone was a candidate for SSKI it's you, as you really need to get over this if you need to be on your feet so much. If SSKI will help, it won't take long to know. And if it doesn't work in a couple weeks, it probably won't, so you can stop it. I'm concerned about the underlying cause with you as you stated " I have an IGM, GTT and SED RATE that are five times normal, with only one other " symptom. " About once a day my whole body gets hot and begins to itch. " As you know, the itch point us to the liver for further investigation. Hepititis is a cause of EN, and I imagine that has been ruled out. The IgM is an " inaccurate " test for herpes from what I've read. Herpes is, by the way, another cause of EN. So keep looking for the cause as I think there are quite a few avenues to explore to get to the bottom of the EN outbreak. These are simply some preliminary ideas from my limited knowledge of medicine and surfing the web. I do feel you will, with a competant doctor uncover the problem. You might want to show the doctor our list of triggers and causes of EN. Here it is: ****** Etiologic factors in erythema nodosum From: http://dermatology.cdlib.org/DOJvol8num1/reviews/enodosum/requena.html http://dermatology.cdlib.org/DOJvol8num1/reviews/enodosum/table1.html 1. Infections * Bacterial infections: *Atypical mycobacterial infections27 * *infections28 Boutonneuse fever29 *Brucellosis30 *Campylobacter infections31 *Cat-scratch disease32 *Chancroid27 *Chlamydia psittaci infections33 *Corynebacterium diphteriae infections27 *Dental Infections *Escherichia coli infections10 *Gonorrhea34 *Leptospirosis35 *Lymphogranuloma venereum36 *Meningococcemia37 *Moraxella catarrhalis infections38 *Mycoplasma pneumonia infections39 *Pasteurella pseudotuberculosis infections40 *Propionibacterium acnes 41 *Pseudomona aeruginosa infections42 *Q fever43 *Salmonella infections44 *Shigella infections45 *Streptococcal infections46 *Syphilis47 *Tuberculosis48 *Tularemia49 *Yersinia infections50 * Viral infections: * Cytomegalovirus infections51 * Hepatitis B52 * Hepatitis C53 * Herpes simplex27 * HIV infection54 * Infectious mononucleosis55 * Measles56 * Milker's nodules57 * Orf56 * Parvovirus B19 infections58 * Varicella59 * Fungal infections: * Aspergillosis60 * Blastomycosis61 *Coccidioidomycosis62 aka Valley Fever http://www.emedicine.com/med/topic539.htm * Dermatophytes63 * Histoplasmosis64 * Sporotrichosis27 * Protozoal infections: Amebiasis65 * Ancylostomiasis27 * Ascariasis66 * Giardiasis65 * Hydatidosis67 * Hookworm infestation27 * Sparganum *larva68 *Toxoplasmosis69 * Trichomoniasis70 2.- Drugs * Acetaminophen71 * Actinomycin-D71 * All-trans retinoic acid72 * Aminopyrine27 * Amiodarone71 * Amoxicillin10 * Ampicillin10 * Antimony27 * Arsphenamine34 * Azathioprine71 * Bromides73 * Busulfan71 * Carbamazepine71 * Carbenicillin71 * Cefdinir71 * Chlordiazepoxide71 * Chlorotrianisene71 * Chlorpropamide71 * Ciprofloxacin71 * Clomiphene71 * Codeine71 *Cotrimoxazole71 *Cytokine Therapy * D-penicillamine74 * Dapsone71 * DES * Diclofenac71 * Dicloxacillin71 * Diethylstilbestrol71 * Disopyramide71 * Echinacea herbal therapy75 * Enoxacin71 * Erythromycin10 * Estrogens71 * Fluoxetine71 * Furosemide71 * Glucagon71 * Gold salts76 *Granulocyte colony-stimulating factor71 *Halogens * Hepatitis B vaccine77 * Hydralazine71 *Ibuprofen71 *Imatinab * Indomethacin71 * Interleukin-278 * Iodides73 * Isotretinoin79 * Leukotriene modifying agents (zileuton and rafirlukast)80 * Levofloxacin71 * Meclofenamate71 * Medroxyprogesterone71 * Meprobamate71 * Mesalamine71 * Methicillin71 * Methimazole71 * Methyldopa71 * Mezlozillin71 * Minocycline81 * Naproxen71 * Nifedipine71 * Nitrofurantoin27 * Ofloxacin71 * Omeprazole82 * Oral contraceptives83 * Oxacillin71 * Paroxetine71 * Penicillin77 * Phenylbutazone60 * Phenytoin57 * Piperacillin71 * Progestins71 * Propylthiouracil84 * Pyritinol34 * Sparfloxacin71 * Streptomycin71 * Sulfamethoxazole71 * Sulfixoxazole71 * Sulfonamides85 *Sulfosalazine71 *Tetracycline * Thalidomide86 * Ticarcilin71 * Trimethoprim87 * Typhoid vaccination88 * Verapamil71 3. Malignant diseases * Adenocarcinoma of the colon89 * Carcinoma of the uterine cervix90 * Hodgkin's disease91 * Leukemia92 * Non-Hodgkin's lymphoma93 * Pancreatic carcinoma94 * Post-radiotherapy for pelvic carcinoma8 * Renal carcinoma78 * Sarcoma34 * Stomach cancer10 4. Miscellaneous conditions * Acne fulminans95 * Adul Still's disease96 * Ankylosing spondylitis97 * Antiphospolipid antibodies syndrome98 * Behçet's syndrome99 * Berger's disease100 * Chronic active hepatitis101 * Celiac disease102 * Colon diverticulosis34 *Crohn's disease103 *Dental infection * Diverticulitis104 *Granulomatous mastitis105 *Hedgehog zoonoses http://www.findarticles.com/p/articles/mi_m0GVK/is_1_11/ai_n8966491 * IgA nephropathy106 * Jellyfish sting107 * Lupus erythematosus108 * Pregnancy109 * Radiotherapy110 * Recurrent polychondritis111 * Reiter's syndrome112 * Rheumatoid arthritis113 * Sarcoidosis114 * Sjögren's syndrome115 * Smoke inhalation in a house fire116 * Sweet's syndrome117 * Systemic lupus erythematosus-like syndrome due to C4 deficiency118 * Takayasu's arteritis119 * Ulcerative colitis120 * Vogt-Koyanagi disease115 * Wegener's granulomatosis121 ***** Love, Quote Link to comment Share on other sites More sharing options...
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