Abstract of Study of Tea and Ovarian Cancer

[Guest guest]

Tea Consumption and Ovarian Cancer Risk in a Population-Based Cohort

http://archinte.ama-assn

org/cgi/content/abstract/165/22/2683?maxtoshow= & HITS=10 & hits=10 & RESULTFORMAT=

fulltext=tea+ovarian+cancer & searchid=1134948511854_1385 & stored_search= & FIRSTI

DEX=0 & journalcode=archinte

na C. Larsson, MSc; Alicja Wolk, DMSc

Arch Intern Med. 2005;165:2683-2686.

Background Substantial evidence from laboratory studies indicates that green

and black tea preparations may protect against various cancers. Few

epidemiologic studies, however, have examined the relationship specifically

between tea consumption and risk of ovarian cancer.

Methods We prospectively examined the association between tea consumption

and risk of ovarian cancer in 61 057 women aged 40 to 76 years who were

participants in the population-based Swedish Mammography Cohort.

Participants completed a validated 67-item food frequency questionnaire at

enrollment between 1987 and 1990 and were followed for cancer incidence

through December 2004.

Results During an average follow-up of 15.1 years, 301 incident cases of

invasive epithelial ovarian cancer were ascertained. Tea consumption was

inversely associated with the risk of ovarian cancer after controlling for

potential confounders (P for trend, .03). Compared with women who never or

seldom (less than monthly) consumed tea, the multivariate hazard ratios for

those who consumed less than 1 cup per day, 1 cup per day, and 2 or more

cups per day were 0.82 (95% confidence interval [CI], 0.62-1.08), 0.76 (95%

CI, 0.56-1.04), and 0.54 (95% CI, 0.31-0.91), respectively. Each additional

cup of tea per day was associated with an 18% lower risk of ovarian cancer

(multivariate hazard ratio, 0.82; 95% CI, 0.68-0.99).

Conclusion These results suggest that tea consumption is associated with a

reduced risk of epithelial ovarian cancer in a dose-response manner.

Author Affiliations: Division of Nutritional Epidemiology, The National

Institute of Environmental Medicine, Karolinska Institutet, Stockholm,

Sweden.

RELATED ARTICLES IN ARCHIVES OF INTERNAL MEDICINE

In This Issue of Archives of Internal Medicine

Arch Intern Med. 2005;165:2555.

FULL TEXT

http://archinte.ama-assn.org/cgi/content/abstract/165/22/2683?maxtoshow= & HITS=10\

& hits=10 & RESULTFORMAT= & fulltext=tea+ovarian+cancer & searchid=1134948511854_1385 & s\

tored_search= & FIRSTINDEX=0 & journalcode=archinte