Guest guest Posted July 27, 2005 Report Share Posted July 27, 2005 Hi there - I did a search, but could not find what I was looking for. I have some questions regarding transitioning from opioids to LDN. How long does someone need to be off of an opioid before beginning LDN? Is the LDN strong enough or provide enough of an endorphorphin release to cover pain? and throughout the day? Is there anyone here that has gone off of oxycontin and successfully replaced it with LDN? Is there something you can use for pain relief (perhaps a non-opioid med) while transitioning? I have severe pain from lyme, fibro, severe spinal disorders. Also, I am non-functional from the fatigue from CFIDS, adrenal exhaustion, and Hashimotos as well as dealing with severe pain from the other health issues mentioned. I take oxy 4 times a day so I am not sure how to transition to LDN without going beserk from uncontrolled pain. I sure would love to be able to give my immune system a chance to repair itself. Tonkinese Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 27, 2005 Report Share Posted July 27, 2005 For those of you in the first months of LDN therapy Dr. Bob Lawrence from the UK who has MS & uses LDN himself explains why the temporary increase in MS symptoms. When starting this LDN(Low Dose Naltrexone) therapy in the treatment of MS, there may also be some initial transient, though temporary, increase in MS symptoms. Experience in using this method has demonstrated most commonly, such as disturbed sleep, occasionally with vivid, bizarre and disturbing dreams, tiredness, fatigue, spasm and pain. These increased symptoms would not normally be expected to last more than seven to ten days. Rarely, other transient symptoms have included more severe pain and spasm, headache, diarrhea or vomiting. These additional symptoms would appear to be associated with the previous frequent use of strong analgesics, which effectively create an addiction and dependency, thus increasing the body's sensitivity to pain. This temporary increase in symptoms may also perhaps be explained when we consider the manner in which this drug is expected to work. In addition, because LDN will also block the analgesic effects of any opiate drugs (includes codeine, dihydrocodeine, morphine, pethidine or diamorphine) presently being taken, the use of LDN will initially greatly increase the level of pain experienced. It is therefore advisable that any opiate-like drugs be discontinued at least two weeks before this treatment is initiated. When starting the treatment it is essential that any untoward or adverse side-effects are reported immediately so that the treatment process can be further assessed and, if necessary, modified. Initially, MS occurs due to a reduction in the activity of the controlling influence of the suppressor T-cells within the immune system. During an acute relapse, the overall number of T-cells is reduced, the normal balance of helper T-cells and suppressor T-cells is disrupted and the damaging helper (CD-4) T-cells tend to predominate. This is the situation most pronounced during an acute relapse but occurs similarly, but to a lesser extent, in chronic progressive MS. Under the influence of LDN there will be an expected increase in the overall numbers of T-cells but, because the CD-4, helper T-cells tend to predominate at this time, an increase in their numbers will expectedly tend to increase MS symptoms. It is only when the numbers of suppressor T-cells effectively catch up; that the normal balance is restored and symptoms once again diminish and improve. In addition, because LDN stimulates the immune system and many of the drugs routinely used by the NHS in the treatment of MS further suppress the immune system, LDN cannot be used in company with steroids, beta interferon, methotrexate, azathioprine or mitozantrone or any other immune suppressant drug. If there is any doubt, please submit a full list of the drugs you are presently taking so that their compatibility may be assessed. Dr. M R Lawrence Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 27, 2005 Report Share Posted July 27, 2005 First of all, three different pharmacists have told me 12 hours. Others have said 6. Oxycocotin is strong so I would go for the 12 hours. My friend swears by 10,000 mgs powdered MSM. I HAVE JUST STARTED IT DUE TO A NECK INJURY AND WILL KEEP EVERYONE POSTED about my experience. I have also heard of am Empulse Device and would suggest a product such as Wobenzyme or something comparable at high doses. The fish oils are good for this as well. However, you must take more than the bottle says. If itsays 2, take 4 or 6 with vitamin E or it oxidizes and produces free radicals. Another thing that might be helpful is hyalauronic acid depending on what her pain is a result of. Massage therapy, swimming, yoga, meditation,pilates, hydrotherAPY. tHESE ARE ALL OPTIONS DEPENDING UPON HER PHYSICAL CONDITION. sorry about the cap button. i hit it by accident. Physical therapy with cervical traction or one of the at home devices could also be an option. A good pain releiving gel is Sombra and can be purchased on the computer. You must wean yourself off slowly from this drug under a doctors supervision. The best thing is to move as much as possible whatever type of movement you are able to perform. It will bring about small changes which will become cumullative over time. Best Wishes, Kathy P.S. Have you checked into low light laser therapy, prolotherapy, or hyalauronic injections? [low dose naltrexone] How to transition from pain to LDN? Hi there - I did a search, but could not find what I was looking for. I have some questions regarding transitioning from opioids to LDN. How long does someone need to be off of an opioid before beginning LDN? Is the LDN strong enough or provide enough of an endorphorphin release to cover pain? and throughout the day?Is there anyone here that has gone off of oxycontin and successfully replaced it with LDN?Is there something you can use for pain relief (perhaps a non-opioid med) while transitioning?I have severe pain from lyme, fibro, severe spinal disorders. Also, I am non-functional from the fatigue from CFIDS, adrenal exhaustion, and Hashimotos as well as dealing with severe pain from the other health issues mentioned.I take oxy 4 times a day so I am not sure how to transition to LDN without going beserk from uncontrolled pain.I sure would love to be able to give my immune system a chance to repair itself.Tonkinese Quote Link to comment Share on other sites More sharing options...
Recommended Posts
Join the conversation
You are posting as a guest. If you have an account, sign in now to post with your account.
Note: Your post will require moderator approval before it will be visible.