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RE: Fwd: [CO-CURE] MED: Mercury and secretin in autism--the connection

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Rich,

Very intersting lines you have drawn here! My nine year old son

started IV secretin at age 2.5 during endoscopy. This was just after

the Beck story surfaced. It was miraculous for him, after second

infusion his development started again after a regression at 18 mos

of age. We did infusions for 4 years. The french frie theory is most

ingtriquing since my son still craves them when his gut is flared,

protein is hard on him.

We started oral liquid LDN 3 weeks ago and have seen amazing

improvement in mood, appetite, and play skills (he is very high

functioning). His gut is still intolerant of casien/gluten and still

craving the fries! Hopefully this will get better.

Before we started this I read many posts on this list and was amazed

by the high mercury levels of some members!

>

> From Rich Van Konynenburg, Ph.D. <richvank@A...>:

>

>

> I think I have just cracked the connection between secretin and

mercury

> toxicity in autism. This may have some relevance to CFS as well,

since

> mercury toxicity is a major factor in many cases of CFS.

>

> For background, some of you may know that some years back it was

> accidentally discovered by Virginia Beck, an autism mother, that an

> injection of the secretin produced by the Karolinska Institute in

Sweden

> (used for a pancreatic function test) helped improve her son's

autism

> symptoms. This led to quite a flurry in the autism community, and a

> synthetically made pure secretin was tested and failed to work.

However,

> the secretin extracted from pigs did work, and Dr. Gregg

proposed

> that it was because the pig version contained prosecretin, which

would last

> longer in the body than actual secretin. Dr. Gregg began supplying

dried

> pig duodenum powder to those who requested it, and many autism

parents

> reported tha! t this did help.

>

> Now we see that there is overwhelming evidence that there is a

connection

> between mercury and autism, particularly ethylmercury coming from

the

> increased number of vaccinations that were required in the children

as time

> went on.

>

> I've been struggling with the question of what could be the

connection

> between mercury toxicity and the secretin effect.

>

> Now I think I have it. As you may know, the main toxic biochemical

effect

> of mercury in the body is to bind to sulfur atoms that are found in

the

> cysteine residues of enzymes and other proteins. When this occurs,

it

> blocks the ability of these sulfur atoms to perform their normal

> functions. In many cases, they normally bind to each other within

protein

> chains to form disulfide bonds, which give the protein molecules

their

> characteristic structure.

>

> I just learned that the receptors for secretin contain six cysteine

> residues, that these residues n! ormally form three disulfide

bonds, and

> that these bonds are critical to the operation of the secretin

receptor. I

> therefore suggest that the connection between mercury toxicity and

the

> secretin malfunction in autism is explained by mercury binding to

cysteine

> residues in secretin receptors, thus distorting their structures

and their

> function. I think this pulls these observations together nicely.

>

> I think this also explains why some children with autism who will

eat only

> french fries before mercury detox treatment are reported to accept

more

> normal diets afterward. French fries consist largely of starch

that has

> been processed at a high temperature, breaking its chains and

making it

> fairly easy to be further broken down to glucose, which can be

> absorbed. It thus does not require much digestion, and therefore a

person

> without much secretin function, who would therefore not put out much

> pancreatic juice, would still be able to absorb glucose fairly

readily from

> french fries. Protein-containing foods wou! ld be much more

difficult to

> cope with, without secretin, and as Dr. Gregg has suggested, the

stomach

> acid provoked by ingestion of proteins would not be neutralized

well by

> pancreatic bicarbonate in the duodenum if the secretin function is

> impaired. Thus, the acid could attack the wall of the intestine,

causing

> pain. This may be the main reason these kids stick to french fries

(or

> grapes, which have a lot of glucose).

>

> Rich Van Konynenburg, Ph.D.

>

> ---------------------------------------------

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spectrum of

> opinion concerning medical, research and political aspects of

ME/CFS and/or

> FMS. We take no position on the validity of any specific scientific

or

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Both interesting and logical. Not

the only thing going on, but certainly a good piece of the puzzle. Well

worth knowing.

Bruce Guilmette, Ph.D.

Survive Cancer Foundation, Inc.

http://www.survivecancer.net

From: low dose naltrexone [mailto:low dose naltrexone ] On Behalf Of cmrichards@...

Sent: Monday, July 25, 2005 7:13

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Subject: [low dose naltrexone] Fwd:

[CO-CURE] MED: Mercury and secretin in autism--the connection

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