Increased sexual intensity caused by naltrexone .... (study included)

[Guest guest]

I hesitated to mention this as i didnt think it really was true but

I have *confirmed* it now ater many days on naltrexone, all sexual

intensity (orgasm) and anything related is quite more powerful... I

have found evidence supporting this.. apprently naltrexone does

indeed increase sexual intensity, in men at least... :

Anyone notice this? Nice side effect!

TI - Naltrexone-induced augmentation of sexual response in men

AB - BACKGROUND: To ascertain the role of endogenous opioids in

sexual response, naltrexone, an opiate receptor antagonist, was

administered to men, and its effect on selected self-report measures

of sexual response to masturbation was recorded. METHODS: The data

are based on results from 20 healthy, sexually active (alone or with

a partner) men, aged 20-29 years, who ingested naltrexone (25 mg/day

x 3) or placebo in a randomized, double-blind crossover design.

There was at least a 14- day interval between drug and placebo

treatment. Between 18 and 22 h after the most recent dose of drug or

placebo, subjects viewed sexually explicit videos in privacy for 2

h. They were instructed to masturbate and have as many orgasms as

desired. The following three different self- report measures of

their responses were recorded: number of orgasms; intensity of

sexual arousal, and orgasmic intensity. RESULTS: Under the

naltrexone condition, the volunteers experienced a significantly

greater mean number of orgasms (3.4 +/- 0.2 SEM) than under the

placebo condition (2.6 +/- 0.3). The total number of orgasms was 67

under the naltrexone condition and 51 under the placebo condition.

At the first orgasm, the measure of intensity of arousal was

significantly greater in the naltrexone (3.9 +/- 0.2) than placebo

(3.4 +/- 0.2) condition, and the measure of orgasmic intensity was

significantly greater in the naltrexone (3.7 +/- 0.2) than in the

placebo (3.0 +/- 0.3) condition. CONCLUSIONS: The present study

provides evidence that endogenous opioids modulate orgasmic response

and the perceived intensity of sexual arousal and orgasm in men. The

findings suggest that naltrexone could be clinically useful in cases

of inhibited sexual desire and erectile dysfunction

SO - Arch Med Res 2001 May ;32(3):221-226

[Guest guest]

Hmmm. Can't say I've noticed *that*, but it sounds good.

My hair and finger nails do grow a lot faster than they did before LDN

though...