Re: Is Gradually Increasing LDN Dose Recommended?

[Guest guest]

Many people have different reactions. This is probably why there is not set

way or dosage to start. If Skip says try it in increments of 1.5 going up

slowly, then he is probably noticing a trend in what is working best for a

majority of people. It maybe that they are experiencing less side effects

and getting use to the medication in their system slowly.

Aletha

[low dose naltrexone] Is Gradually Increasing LDN Dose Recommended?

> Hi,

> I have CFS, am interested in trying LDN. In prepping for an appoinment

> with my doc tomorrow I called a few of the " approved " pharmacies to get

> some information re: available dosages, fillers used, etc. Along the

> way, a pharmacist at Skip's told me that it is recommended (including

> from Dr. Bihari as far as he knew?) to gradually build toward the 4.5

> nightly dose by starting at 1.5 mg for 30 days, then increasing to 3.0

> mg for 30 days, then finally to the 4.5 mg after 60 days.

>

> This sounds sensible enough albeit slow (and is what I was planning on

> doing anyway to avoid worsening my already very disrupted sleep), but I

> was surprised that in all my research on various LDN sites I had never

> seen that specific dosage recommendation. Is anyone familiar with this

> specific " recommended " protocol for starting LDN? Is this what Dr.

> Bihari or other knowledgeable docs are using? Please let me know.

> Thanks,

> Jim

>

>

>

>

>

>

[Guest guest]

that is what i did until i increased to 3.0 and stayed there. i did it that way because i wanted to see if i would have any side effects and i felt more comfortable doing it that way. i think dr. bihari recommends starting at 3.0 or 4.5 depending on body weight but the real important thing is wharf you feel comfortable doing and just getting started whatever that initial dose may be in the acceptable range. good luck, kathy

[low dose naltrexone] Is Gradually Increasing LDN Dose Recommended?

Hi,I have CFS, am interested in trying LDN. In prepping for an appoinment with my doc tomorrow I called a few of the "approved" pharmacies to get some information re: available dosages, fillers used, etc. Along the way, a pharmacist at Skip's told me that it is recommended (including from Dr. Bihari as far as he knew?) to gradually build toward the 4.5 nightly dose by starting at 1.5 mg for 30 days, then increasing to 3.0 mg for 30 days, then finally to the 4.5 mg after 60 days.This sounds sensible enough albeit slow (and is what I was planning on doing anyway to avoid worsening my already very disrupted sleep), but I was surprised that in all my research on various LDN sites I had never seen that specific dosage recommendation. Is anyone familiar with this specific "recommended" protocol for starting LDN? Is this what Dr. Bihari or other knowledgeable docs are using? Please let me know.Thanks,Jim

[Guest guest]

LDN is very dose critical what you are trying to achieve is the dose that boosts your immune system as much as possible. The problem is if you go about .5 MG over that dose you will suppress your immune system and that will do you more harm than the potential good LDN can do for you. It seems for about 75% of people 4.5MG is the right dose but my wife fits into the other 25% and she now uses 2.8MG for MS with great results. Most recommend starting at 3mg and moving up to 4.5 after a month and that is probably sensible advise. For a very few 3MG is too much and they have to reduce to 1.5MG. There has been lots of debates and surveys on this board trying to work out dosage based on sex, height, weight etc and as far as I can see no one has improved on try it for yourself. When my wife moved to 4.5MG after a superb result with 3MG it was a total disaster much worse than not taking LDN at all. If she had started on 4.5MG it would probably have frightened us of using it at all and missed what has been the best treatment for anything that she has ever had. This is not rocket science you just need to back of the dose if you start getting worse. Please remember this advise is based on treating MS but I would imagine you will find similar issues with CFS. All the very best.

Dave

Date: Mon, 11 Jul 2005 16:47:42 -0000 From: "naturefreak2002" <naturefreak2002@...>Subject: Is Gradually Increasing LDN Dose Recommended?Hi,I have CFS, am interested in trying LDN. In prepping for an appoinment with my doc tomorrow I called a few of the "approved" pharmacies to get some information re: available dosages, fillers used, etc. Along the way, a pharmacist at Skip's told me that it is recommended (including from Dr. Bihari as far as he knew?) to gradually build toward the 4.5 nightly dose by starting at 1.5 mg for 30 days, then increasing to 3.0 mg for 30 days, then finally to the 4.5 mg after 60 days.This sounds sensible enough albeit slow (and is what I was planning on doing anyway to avoid worsening my already very disrupted sleep), but I was surprised that in all my research on various LDN sites I had never seen that specific dosage recommendation. Is anyone familiar with this specific "recommended" protocol for starting LDN? Is this what Dr. Bihari or other knowledgeable docs are using? Please let me know.Thanks,Jim

[Guest guest]

Hi ,

I totally agree with you. I started with 4.5 mg

and had superb results. Because of stiffness

I went down - after 5 months - to 3.0 mg.

My m.s. got worse; a total disaster (worse then before ldn).

Then I began with 4.5 mg again (thank you Bren !) and

I got the good results again. The stiffness remained te same

all the time, but I can handle it.

We have to be glad we have to find out for ourselves

wich dosage fits our individual body best. Normally there is

one standard dosage (the average) but we are lucky to

have to find out ourselves. By the way: I hate doctors

(although there are plenty good ones).

Greetings, Simon (the Netherlands)

>From: " " <davidtaylor@...>

>Reply-low dose naltrexone

><low dose naltrexone >

>Subject: [low dose naltrexone] RE: Is Gradually Increasing LDN Dose

>Recommended?

>Date: Tue, 12 Jul 2005 10:36:32 +0100

>

>

>

>LDN is very dose critical what you are trying to achieve is the dose that

>boosts your immune system as much as possible. The problem is if you go

>about .5 MG over that dose you will suppress your immune system and that

>will do you more harm than the potential good LDN can do for you. It seems

>for about 75% of people 4.5MG is the right dose but my wife fits into the

>other 25% and she now uses 2.8MG for MS with great results. Most recommend

>starting at 3mg and moving up to 4.5 after a month and that is probably

>sensible advise. For a very few 3MG is too much and they have to reduce to

>1.5MG. There has been lots of debates and surveys on this board trying to

>work out dosage based on sex, height, weight etc and as far as I can see no

>one has improved on try it for yourself. When my wife moved to 4.5MG after

>a superb result with 3MG it was a total disaster much worse than not taking

>LDN at all. If she had started on 4.5MG it would probably have frightened

>us of using it at all and missed what has been the best treatment for

>anything that she has ever had. This is not rocket science you just need to

>back of the dose if you start getting worse. Please remember this advise is

>based on treating MS but I would imagine you will find similar issues with

>CFS. All the very best.

>

>Dave

>

> Date: Mon, 11 Jul 2005 16:47:42 -0000

> From: " naturefreak2002 " <naturefreak2002@...>

>Subject: Is Gradually Increasing LDN Dose Recommended?

>

>Hi,

>I have CFS, am interested in trying LDN. In prepping for an appoinment

>with my doc tomorrow I called a few of the " approved " pharmacies to get

>some information re: available dosages, fillers used, etc. Along the

>way, a pharmacist at Skip's told me that it is recommended (including

>from Dr. Bihari as far as he knew?) to gradually build toward the 4.5

>nightly dose by starting at 1.5 mg for 30 days, then increasing to 3.0

>mg for 30 days, then finally to the 4.5 mg after 60 days.

>

>This sounds sensible enough albeit slow (and is what I was planning on

>doing anyway to avoid worsening my already very disrupted sleep), but I

>was surprised that in all my research on various LDN sites I had never

>seen that specific dosage recommendation. Is anyone familiar with this

>specific " recommended " protocol for starting LDN? Is this what Dr.

>Bihari or other knowledgeable docs are using? Please let me know.

>Thanks,

>Jim

>

>

>

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[Guest guest]

Does anyone out there know what part of the immune system LDN affects?

With MS and CFS certain parts of the immune system are upregulated as

with most autoimmune disease.

[Guest guest]

I think your views on this are entirely accurate. The right dose is critical and it doesn't take alot of guesswork to know. Your body tells you right away. Very well said.

Is Gradually Increasing LDN Dose Recommended?Hi,I have CFS, am interested in trying LDN. In prepping for an appoinment with my doc tomorrow I called a few of the "approved" pharmacies to get some information re: available dosages, fillers used, etc. Along the way, a pharmacist at Skip's told me that it is recommended (including from Dr. Bihari as far as he knew?) to gradually build toward the 4.5 nightly dose by starting at 1.5 mg for 30 days, then increasing to 3.0 mg for 30 days, then finally to the 4.5 mg after 60 days.This sounds sensible enough albeit slow (and is what I was planning on doing anyway to avoid worsening my already very disrupted sleep), but I was surprised that in all my research on various LDN sites I had never seen that specific dosage recommendation. Is anyone familiar with this specific "recommended" protocol for starting LDN? Is this what Dr. Bihari or other knowledgeable docs are using? Please let me know.Thanks,Jim