Vitamin D prevents many cancers

[Guest guest]

D.I.N.O.M.I.T. An acronym for the model of cancer development " stages " . Each

letter represents a " stage " in the development of Cancer. The beginning

stage...The Letter " D " ... stands for: Disjunction, or loss of intercellular

communication.

Doctors stated: You can remember how to prevent the " D " stage from happening by

adequate levels of " Vitamin D " . Think about this...they are saying Many Cancers

can be PREVENTED just with vitamin D. They are saying, That being LOW on D is

the FIRST step to developing cancer. wow.

To read an article:

http://www.eurekalert.org/pub_releases/2009-05/uoc--nms052009.php

(I also copied it below for you)

You can also do a youtube search for Dinomit (pronounced Dynomite) and find a

video on it by the doctor who wrote the article.

New model suggests role of low vitamin D in cancer development

In studying the preventive effects of vitamin D, researchers at the s

Cancer Center at the University of California, San Diego, have proposed a new

model of cancer development that hinges on a loss of cancer cells' ability to

stick together. The model, dubbed DINOMIT, differs substantially from the

current model of cancer development, which suggests genetic mutations as the

earliest driving forces behind cancer.

" The first event in cancer is loss of communication among cells due to, among

other things, low vitamin D and calcium levels, " said epidemiologist Cedric

Garland, DrPH, professor of family and preventive medicine at the UC San Diego

School of Medicine, who led the work. " In this new model, we propose that this

loss may play a key role in cancer by disrupting the communication between cells

that is essential to healthy cell turnover, allowing more aggressive cancer

cells to take over. "

Reporting online May 22, 2009 in the ls of Epidemiology, Garland suggests

that such cellular disruption could account for the earliest stages of many

cancers. He said that previous theories linking vitamin D to certain cancers

have been tested and confirmed in more than 200 epidemiological studies, and

understanding of its physiological basis stems from more than 2,500 laboratory

studies.

" Competition and natural selection among disjoined cells within a tissue

compartment, such as might occur in the breast's terminal ductal lobular unit,

for example, are the engine of cancer, " Garland said. " The DINOMIT model

provides new avenues for preventing and improving the success of cancer

treatment. "

Garland went on to explain that each letter in DINOMIT stands for a different

phase of cancer development. " D " stands for disjunction, or loss of

intercellular communication; " I, " for initiation, where genetic mutations begin

to play a role; " N " for natural selection of the fastest-reproducing cancer

cells; " O " for overgrowth of cells; " M " for metastasis, when cancer cells

migrate to other tissues, where cancer can kill; " I " refers to involution, and

" T " for transition, both dormant states that may occur in cancer and potentially

be driven by replacing vitamin D.

While there is not yet definitive scientific proof, Garland suggests that much

of the evolutionary process in cancer could be arrested at the outset by

maintaining vitamin D adequacy. " Vitamin D may halt the first stage of the

cancer process by re-establishing intercellular junctions in malignancies having

an intact vitamin D receptor, " he said.

According to Garland, other scientists have found that the cells adhere to one

another in tissue with adequate vitamin D, acting as mature epithelial cells.

Without enough vitamin D, they may lose this stickiness along with their

identity as differentiated cells, and revert to a stem cell-like state.

Garland said that diet and supplements can restore appropriate vitamin D levels,

and perhaps help in preventing cancer development. " Vitamin D levels can be

increased by modest supplementation with vitamin D3 in the range of 2000

IU/day, " he noted.

The researchers noted that many studies show an apparent beneficial effect of

vitamin D and calcium on cancer risk and survival of patients with breast,

colorectal and prostate cancer. However, there are some studies that have not

found such benefit, especially when taking smoking, alcohol and viruses into

account. While more research needs to be done, Garland recommends that

individuals should have their vitamin D level tested during an annual check up.

Garland and his colleagues have published epidemiological studies about the

potential preventive effects of vitamin D for some two decades. Last year, his

team showed an association between deficiency in sunlight exposure, low vitamin

D and breast cancer. In previous work, they showed associations between

increased levels of vitamin D3 or markers of vitamin D and a lower risk for

breast, colon, ovarian and kidney cancers.

###

Other authors on the study include D. Gorham, Sharif B. Mohr and C.

Garland, UC San Diego.

The s UCSD Cancer Center is one of the nation's 41 National Cancer

Institute-designated Comprehensive Cancer Centers, combining research, clinical

care and community outreach to advance the prevention, treatment and cure of

cancer. For more information, visit http://health.ucsd.edu/cancer