Guest guest Posted April 10, 2001 Report Share Posted April 10, 2001 i think this is a very interesting concept of trying a cancer medicaction for chronic lyme infection....i wonder if this has been done? lyme can cause cancer...wonder if there is a connection her to Novantrone? hhhmmm cheryl In a message dated 4/10/01 9:34:25 AM, larryy@... writes: << To All, Has anyone been given Novantrone infusions? If so, what results? I've included an abstract confirming what was suspected in the etiology of Lyme, i.e. the cetes hiding in the T cell and B cells. Novantrone is a chemotherapy that kills T cells and B cells. I postulate that if the T cells and B cells containing the cetes are killed the cetes are either killed with the T cells and B cells or they are released to be killed by the abx. Please post any experience with Novantrone or any impute. Thanks. Larry NV NOVANTRONE is given intravenously using a procedure called an intravenous (IV) infusion. An IV infusion of NOVANTRONE is given once every 3 months through a needle inserted into a vein in your hand or arm. IV infusion with NOVANTRONE takes a short time to deliver- only 5 to 15 minutes. NOVANTRONE should be given under the supervision of a doctor experienced in using NOVANTRONE or similar drugs. It is usually given in the hospital or doctor's office, but it can also be given in a special infusion center or even at home. Borrelia burgdorferi recovered from infected mammal cells (3/01). Dorward and Larson in the March 2001 issue of Infection and Immunity demonstrate that Bb spirochetes can adhere to mouse lymphocytes and that Bb spirochetes with affinity for mouse lymphocytes can establish disseminated infections in mice. This is the first study to demonstrate the attraction of Bb to mammalian lymphocytes in vivo. The recovery of viable spirochetes in this study from mouse B and T cells indicates that the spirochetes and the lymphocytic cells are in intimate contact with one another in the mammal. While previous work demonstrated that Bb spirochetes could target, adhrere to, and invade primary human B and T lymphocytes in vitro, the exact nature of the in vivo spirochete-lymphocytes interactions could not be demonstrated by electron microscopy in this study; the same lymphocyte preparations from the spleen and blood of infected mice did however produce active spirochetal cultures. The authors speculate that visualization may not have been possible due to a low number of spirochetes per ml. This study supports the suggestion that cellular tropism and lymphocytic-Bb interactions may be mechanisms of persistent infection and disease pathogenesis in the mammalian host. Welcome to Easy Reference: Send a blank email message to: -Unsubscribe - Unsubscribe from the list -Digest - Switch your subscription to a digest format -Normal - Switch your subscription to normal Please send messages not related to Lyme disease (this includes humor and information about other diseases) to -Offtopic The archives can be accessed at The chat room is always open! /chat Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 10, 2001 Report Share Posted April 10, 2001 I did hear of a case of someone who had lyme for many years, developed cancer, was given chemo, and was cured on both diseases. I asked my doctor about it and she said she was following a case where her patient had cancer and was receiving chemo. She would know in a few months. Irene Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 14, 2005 Report Share Posted June 14, 2005 You are in Diseases & Conditions. Choose a TopicAll ConditionsADD/ADHDAllergiesAlzheimer'sArthritisAsthmaBack PainBipolar DisorderBreast CancerCancerCholesterol ManagementDentalDepressionDiabetesEpilepsyEye HealthHeart DiseaseHepatitisHIV/AIDSHypertensionMen's ConditionsMental HealthMigraines/HeadachesMultiple SclerosisOsteoporosisParkinson'sSexual ConditionsSkin & BeautyStrokeWeight ControlWomen's Conditions Heart, Leukemia Warning for MS Drug Novantrone Heart Risks May Be Higher for Multiple Sclerosis Patients With Heart Problems By Miranda HittiWebMD Medical News Reviewed By Brunilda Nazario, MDon Wednesday, May 25, 2005 May 25, 2005 -- The FDA is warning doctors and multiple sclerosis (MS) patients about the risk of heart failure and leukemia from the MS drug Novantrone. Patients may be more vulnerable if they have a history of heart disease or heart problems. Screening for heart failure should be done prior to starting treatment with Novantrone and prior to all doses administered, says the drug's maker, Serono. Patients with heart failure should not receive Novantrone, the company says. A Serono letter to doctors about Novantrone is posted on the FDA's web site. The letter includes a revised warning label, which has what the FDA calls "additional" and "supplemental" information about heart and leukemia risks. About Novantrone Novantrone is used to reduce neurological disability and/or the frequency of clinical relapses in patients with several types of MS, says Serono. Those conditions are secondary (chronic) progressive MS, progressive-relapsing MS, or worsening relapsing-remitting MS. Novantrone is not indicated for patients with primary progressive MS, says Serono. Heart Risks "Diminished cardiac function may occur early on in treatment with Novantrone," says Serono's letter, citing postmarketing reports. "Congestive heart failure, potentially fatal, may occur either during therapy with Novantrone or months to years after termination of therapy," says the revised label. It also says all patients should be carefully assessed for cardiac signs and symptoms -- such as shortness of breath, extreme fatigue with exertion, and leg swelling -- prior to the start of Novantrone therapy. The label says heart risks may be higher in patients taking Novantrone who have current or past heart disease, those who have had (or are getting) radiation therapy to the chest, those who have previously taken cancer-fighting drugs that can affect the heart -- such as anthracyclines or anthracenediones -- and those who are also taking other drugs that could cause heart damage. Page: 1 | 2 Next: Risk of Treatment-Related Leukemia Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 11, 2006 Report Share Posted March 11, 2006 Artie is right about the Novantrone…it is considered chemotherapy. They wanted me to try it but after doing my homework, I decided against it. And then I found LDN---Yeaaaah! Bob Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 19, 2006 Report Share Posted March 19, 2006 I decided not to do the Novantrone also because when I read up on it I didn't like what I read...so I went back to the Copaxone and LDN and I am doing fine with them together...Bob <bob@...> wrote: Artie is right about the Novantrone…it is considered chemotherapy. They wanted me to try it but after doing my homework, I decided against it. And then I found LDN---Yeaaaah! Bob Relax. virus scanning helps detect nasty viruses! Quote Link to comment Share on other sites More sharing options...
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