Latest News As of June 2005

June 13, 2005

LDN Conference a Success: The First Annual LDN Conference, which was

held in NYC at the New York Academy of Sciences, June 11, 2005, was

a success. Some 85 enthusiastic participants heard Dr. Bihari's

keynote message, as well as five panels of researchers, doctors,

pharmacists, and LDN advocates. Next year's conference is planned

for Washington, D.C. Click on the POST-CONFERENCE UPDATE on the

website's home page for more information on the conferences.

Crohn's Study Successful; Large-Scale Trial Planned: Dr. Jill ,

Professor of Gastroenterology at Penn State's Hershey Medical

Center, recently completed an open-label, pilot feasibility study

using low-dose naltrexone in Crohn's disease. As reported previously

on this website, her pilot study began in November 2003. With her

permission, it was reported at the LDN Conference that she was very

pleased with the results of the study, and has submitted an

application to the NIH to conduct a larger placebo-controlled trial.

If it were to happen, it would be the first scientific clinical

trial using LDN to be accomplished at a US medical center.

First Book on LDN Published: Anne Boyle Bradley's new book, " Up

the Creek with a Paddle: Beat MS and Many Autoimmune Disorders with

Low Dose Naltrexone (LDN) " , has the distinction of being the very

first published book devoted to the subject of LDN. The book details

Bradley's own story of how she stumbled across LDN as a treatment

for her husband's MS, and her activities as an LDN activist since.

Bradley was a featured panelist at the First Annual LDN Conference.

Her book is available from Amazon and other major booksellers.

NEJM Article Provides Proof of Principle for LDN: A recent article

in the New England Journal of Medicine ( " Sargramostim for Active

Crohn's Disease " , May 26, 2005) counters a major hurdle to LDN's

acceptance—the unproven (but widely held) idea that autoimmune

diseases are related to an over-aggressive, overactive immune

system. The NEJM article describes the effect on patients with

Crohn's Disease of Granulocyte-Macrophage Colony Stimulating Factor,

an injectable substance that is recognized as a stimulant to the

endogenous immune system in the intestinal tract. Patients treated

in the study experienced a beneficial effect. This article

establishes " proof of principle " that stimulating the immune system—

as LDN does—can be beneficial for autoimmune disease.

June 13, 2005

I love it guys!! Check this out .. I haev a friend who has a sister that used to

work on the Oprah show .. she is going to help me with this .. I will send her

the book tomorrow .. Thanks for everything guys .. you are wonderful! I wanted

to talk to you both but I didn't want to get in your way either .. it was a busy

day ... next time! if anything punches you .. speak up!

Dear Dianne,

I am hoping that you will remember me. I sent each of your staff a letter in

February 2004 with regard to the work of Dr Bernard Bihari, in New York City. I

want to thank you for your response dated April 2004. I completely understand

that Ms Winfrey must receive numerous letters each week soliciting support for

experimental AIDS medications. That is not my intention. We have the funds and a

trial is about to happen in Mali. Since I last wrote much has happened. I will

try to explain briefly but concisely.

I befriended my kids kindergarten teacher, Rosemary Konde. She is about 55, fun

and very smart. I instantly loved talking to her and she said that she enjoyed

my stories. So I emailed her nightly to tell her my story, and when I was done,

I compiled my emails into a manuscript and sent it to a publishing house. The

first publishing house that received it, loved it and ran with it and now I have

a book called " Up the Creek with a Paddle " . I am sending you a copy because I

want you to read it. The Oprah chapter starts at the end of page 134.

Dianne, although my book is personal, this is not and never has been about me.

The fact is that Dr Bihari has discovered something worthy of a Nobel Prize. He

has changed the lives of thousands for the better and the snowball is getting

bigger and bigger everyday. He has linked all illnesses with a disturbed immune

system, ranging from psoriasis to AIDS and found a common factor. They all have

low endorphins. He can boost this hormone nightly and make the immune system

function properly. His results have stood the test of time and testimony. The

drug is cheap with no side effects. I know it sounds crazy but my husband has

Primary Progressive MS and my uncle has Parkinsons and come September they will

be 3 years on LDN (Low Dose Naltrexone) .. and stable. They have not progressed.

They have not experienced even one brand new symptom in 3 years. There are

thousands of similar stories. People have been taking this drug for 20 years

Dianne. My book humanizes the drug and so far has been greatly appreciated by

everyone who has read it because at last there is hope. Chronic degenerative

illnesses can at least be treated, not cured but stopped from getting worse.

Please check Oprah's website. Many people have written to you about LDN. Many

people have also written to you about Bradley. I attended the world's first

LDN conference on June 11th in Manhattan. I was the final speaker and could have

spoke all night. Doctors from all over the world traveled to share their

staggering results. The drug, Naltrexone, is FDA approved and used for treating

heroin addicts at 50mg. But low Dose Naltrexone at 3 to 4.5mg is not medically

recognized for treating disturbed immune systems. Any physician can prescribe it

off label as it is listed in the PDR but it needs the scientific recognition of

the medical community via a large scale clinical trial and that is about to

happen.

It is about to happen in Mali!! I am so excited about this I can hardly contain

myself. The potential this drug holds for HIV and AIDS in countries like Africa

is mind blowing and it is all about to happen. I am not exaggerating when I tell

you, history is being written.

Seyni Nafo is wonderful young guy with an ambition to bring LDN to his homeland,

Mali. He has succeeded in speaking with the President who has agreed to pay for

a trial .. so he is setting it all up. He has the protocol in place ready for

the ethics committee. The trial will consist of 150 people ... 3 groups of 50 ..

HIV patients with good CD4 count will get LDN, then a group with AIDS will get

the standards AIDS medications, then a group with AIDS get the standard AIDS

medications plus LDN. By the end of July 2005 funding should be in place and

this trial will begin. The trial will take 12 months. When LDN proves to make a

statistical difference the world will wake up because the impact LDN can have on

HIV and AIDS is mind blowing. The trial costs 263000 US dollars and if they

produced LDN locally it would cost less than 10 US dollars per patient per year.

I am deadly, deadly, deadly excited about Mali. You see according to Dr Bihari's

20 years of results on HIV and AIDS, LDN prevents HIV developing into AIDS and

it is a simple pill taken nightly. Imagine the implications!!

This is my desire Dianne. I want Oprah to interview Dr Bihari. That is all. The

entire audience could be filled with people willing to testify on his behalf. He

is in his mid seventies and very humble with a wonderful sense of humor. He

wants nothing other than LDN to be scientifically recognized so that it can

reach the masses.

I realize the double edged sword. It sums up how messed up our system really is.

If LDN gets medical recognition it will probably cost 10 times more than it does

now, but if that is the price we have to pay, then that is the price I am

willing to pay to get the drug to all who need it. To increase the price is just

wrong, plain and simple, but the makers feel they deserve to make money and

because LDN is cheap and already FDA approved I predict that is how they will do

it. The health industry is a big one ... but that does not make it right.

I sincerely hope you will give this matter the attention it deserves and needs.

All the very Best

Bradley

Email ... mboylebradley@...

Phone .. 201 612 6864

Address 135 Millington Drive

Midland Park

New Jersey 07432

USA

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From: edit3737 <dgluck@...>

Date: Mon Jun 13 08:51:19 CDT 2005

low dose naltrexone

Subject: [low dose naltrexone] Latest News As of June 2005