can spiro RAISE BP before it begins to lower it?

[Guest guest]

I'm going to re-phrase my other question more directly before it turns into a derail about DASH and sodium:I've been on spiro for a week.I eat no more than 800mg/sodium per day.Since starting the spiro, my home BP average has gone from 142/92 to 168/106, the highest I have ever seen.My nephrologist is advising me to increase the spiro tomorrow and I'm a little scared.So, can anybody answer the question - is it normal for spiro to make BP higher before it starts to lower it?And if we want to talk sodium - can 800 mg be too high of an intake if one is especially sensitive?Thanks.-msmith1928Nulliparous female, 46, 5'3", 120 lbs, polymenorrhea, hyperinsulinemia, hereditary fructose intolerance, lactose intolerance, probable gluten intolerance. Current meds are spiro 12.5mg/dday, potassium 20MEQ/day, singulair 10mg, norethindrone .35mg to regulate polymenorrhea, cyclobenzaprine 5-10mg when needed, fexofenadine 180mg as needed. Low sodium, fructose- and grain-free diet. Known drug allergies include PCN, sulfa, tetracycline.1cm left adrenal nodule, supine aldosterone 28.5/renin 0.2, potassium <2.9 (when not taking supplements), 25mg spiro caused gynecomastia and polymenorrhea. AVS showed right adrenal overproduces aldo; unable to sample left; proceeding as if my hyperaldosteronism is bilateral.

[Guest guest]

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I'm going to re-phrase my other question more directly before it turns into a derail about DASH and sodium:I've been on spiro for a week.I eat no more than 800mg/sodium per day.Since starting the spiro, my home BP average has gone from 142/92 to 168/106, the highest I have ever seen.My nephrologist is advising me to increase the spiro tomorrow and I'm a little scared.So, can anybody answer the question - is it normal for spiro to make BP higher before it starts to lower it?And if we want to talk sodium - can 800 mg be too high of an intake if one is especially sensitive?Thanks.-msmith1928Nulliparous female, 46, 5'3", 120 lbs, polymenorrhea, hyperinsulinemia, hereditary fructose intolerance, lactose intolerance, probable gluten intolerance. Current meds are spiro 12.5mg/dday, potassium 20MEQ/day, singulair 10mg, norethindrone .35mg to regulate polymenorrhea, cyclobenzaprine 5-10mg when

needed, fexofenadine 180mg as needed. Low sodium, fructose- and grain-free diet. Known drug allergies include PCN, sulfa, tetracycline.1cm left adrenal nodule, supine aldosterone 28.5/renin 0.2, potassium <2.9 (when not taking supplements), 25mg spiro caused gynecomastia and polymenorrhea. AVS showed right adrenal overproduces aldo; unable to sample left; proceeding as if my hyperaldosteronism is bilateral.

[Guest guest]

Please tell me what test to ask for next time. All my doctor seems to be

checking is my BP and K.

>

> > I'm going to re-phrase my other question more directly before it turns into

a derail about DASH and sodium:

> >

> >

> > I've been on spiro for a week.

> > I eat no more than 800mg/sodium per day.

> > Since starting the spiro, my home BP average has gone from 142/92 to

168/106, the highest I have ever seen.

> > My nephrologist is advising me to increase the spiro tomorrow and I'm a

little scared.

> >

> > So, can anybody answer the question - is it normal for spiro to make BP

higher before it starts to lower it?

> >

> > And if we want to talk sodium - can 800 mg be too high of an intake if one

is especially sensitive?

> >

> > Thanks.

> >

> > -msmith1928

> > Nulliparous female, 46, 5'3 " , 120 lbs, polymenorrhea, hyperinsulinemia,

hereditary fructose intolerance, lactose intolerance, probable gluten

intolerance. Current meds are spiro 12.5mg/dday, potassium 20MEQ/day, singulair

10mg, norethindrone .35mg to regulate polymenorrhea, cyclobenzaprine 5-10mg when

needed, fexofenadine 180mg as needed. Low sodium, fructose- and grain-free diet.

Known drug allergies include PCN, sulfa, tetracycline.

> > 1cm left adrenal nodule, supine aldosterone 28.5/renin 0.2, potassium <2.9

(when not taking supplements), 25mg spiro caused gynecomastia and polymenorrhea.

AVS showed right adrenal overproduces aldo; unable to sample left; proceeding as

if my hyperaldosteronism is bilateral.

> >

>

[Guest guest]

, that's exactly what I'm starting to wonder!

I mean... I know I have high aldo, low renin, low K, HTN, and a right adrenal

that's overproducing aldo. But I'm beginning to wonder if there's some other

issue that's being missed, and the hyperaldo is secondary, and the HTN is

tertiary.

But from what little I know about it, I think most causes of secondary hyperaldo

are kidney related, and I think I've had all that checked out.

> >

> > > I'm going to re-phrase my other question more directly before it turns

into a derail about DASH and sodium:

> > >

> > >

> > > I've been on spiro for a week.

> > > I eat no more than 800mg/sodium per day.

> > > Since starting the spiro, my home BP average has gone from 142/92 to

168/106, the highest I have ever seen.

> > > My nephrologist is advising me to increase the spiro tomorrow and I'm a

little scared.

> > >

> > > So, can anybody answer the question - is it normal for spiro to make BP

higher before it starts to lower it?

> > >

> > > And if we want to talk sodium - can 800 mg be too high of an intake if one

is especially sensitive?

> > >

> > > Thanks.

> > >

> > > -msmith1928

> > > Nulliparous female, 46, 5'3 " , 120 lbs, polymenorrhea, hyperinsulinemia,

hereditary fructose intolerance, lactose intolerance, probable gluten

intolerance. Current meds are spiro 12.5mg/dday, potassium 20MEQ/day, singulair

10mg, norethindrone .35mg to regulate polymenorrhea, cyclobenzaprine 5-10mg when

needed, fexofenadine 180mg as needed. Low sodium, fructose- and grain-free diet.

Known drug allergies include PCN, sulfa, tetracycline.

> > > 1cm left adrenal nodule, supine aldosterone 28.5/renin 0.2, potassium <2.9

(when not taking supplements), 25mg spiro caused gynecomastia and polymenorrhea.

AVS showed right adrenal overproduces aldo; unable to sample left; proceeding as

if my hyperaldosteronism is bilateral.

> > >

> >

>