Guest guest Posted January 9, 2009 Report Share Posted January 9, 2009 Hi , Where did you read info about Probotics? It sounds interesting, I love yogurt, would like to find out more about it. Take Care, ________________________________ To: Stillsdisease Sent: Friday, January 9, 2009 7:11:58 PM Subject: Probiotics Question Hey gang, Has anyone tried probiotics for Still's? I've been reading some interesting stuff on their effect on autoimmune disorders, particularly lowering CRP and lessening cytokine response. Probiotics are the " good " bacteria found in yoghurt, miso, fermented drinks, etc.; you can also buy probiotic supplements, although they aren't regulated like a med. in Maine Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 10, 2009 Report Share Posted January 10, 2009 Hi , I have access to a quite a few research databases and try to keep up on the latest studies. I'm sort of twiddling my thumbs here waiting for the FDA to approve Tocilizumab (I'm on prednisone, MTX, and Kineret right now but still flaring). I'll cut and paste below something worth reading. in Maine This was in World Journal of Gastroenterology, April 2008: >>>>Probiotic bacteria, defined as living microorganisms that have beneficial effects on human health, have mostly been studied in the prevention and treatment of different gastrointestinal diseases and allergies. Probiotic products, however, are usually consumed by the general, healthy population but not much is known what kind of effects they have on the immune system in healthy adults. It is not clear how probiotics exert their health effects, but one of the most probable action mechanisms is the modulation of immune responses via the gut's mucosal immune system. This study investigated the immunomodulatory effects of probiotics bacteria in healthy adults. It was found that probiotics have an anti-inflammatory potential seen as a decrease in serum CRP levels and as a reduction in bacteria-induced production of proinflammatory cytokines in peripheral blood mononuclear cells. Understanding of the specific immunomodulatory effects of probiotics may help in designing future probiotics for targeted purposes. As the effects in the present study were investigated in healthy adults, the real impact of probiotics on inflammatory variables warrants further evaluation during inflammatory processes and in individuals suffering from various types of inflammatory or autoimmune diseases.<<<<< ### This research was carried out in collaboration with University of Helsinki (Finland), Valio Research Centre (Finland), and the National Public Health Institute (Finland). Part of the study was funded by the Academy of Finland. Reference: Kekkonen RA, Lummela N, Karjalainen H, Latvala S, Tynkkynen S, Järvenpää S, Kautiainen H, Julkunen I, Vapaatalo H, Korpela R. Probiotic intervention has strain-specific anti-inflammatory effects in healthy adults. World J Gastroenterol 2008; 14(13): 2029-2036 http://www.wjgnet.com/1007-9327/14/2029.aspCorrespondence to: Riitta Korpela PhD, Assistant Professor, University of Helsinki, Institute of Biomedicine, Pharmacology, PO Box 63, 00014 University of Helsinki, Finland. riitta.korpela@... Telephone: +358-10-3813026 Fax: +358-10-3813019 > > Hi , > > Where did you read info about Probotics? It sounds interesting, I love yogurt, would like to find out more about it. > > Take Care, > > > > > > ________________________________ > > To: Stillsdisease > Sent: Friday, January 9, 2009 7:11:58 PM > Subject: Probiotics Question > > > Hey gang, > Has anyone tried probiotics for Still's? I've been reading some > interesting stuff on their effect on autoimmune disorders, > particularly lowering CRP and lessening cytokine response. > > Probiotics are the " good " bacteria found in yoghurt, miso, fermented > drinks, etc.; you can also buy probiotic supplements, although they > aren't regulated like a med. > in Maine > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 10, 2009 Report Share Posted January 10, 2009 Hi , Thanks for the info, Last night my Rheumy stopped my Kineret, due to a severe allergic reaction. So now I am in the same boat as you are waiting on the approval of the Tocilizumab. I was on the same combo you are, except they had added Plaquenil. My medication resources are dewindling quickly, I -have multiple organ involvement also. Got B-Cell Lymphoma induced by Enbrel, they told me that was very rare. My docs are thinking of trying Cytoxan, it is a chemotherapy drug that will treat my Lymphoma, but also there have been a few studies of treating Still's with it, so I might get to kill 2 birds with one stone. Thanks again for the info, if you find anything else interesting send it my way. I have alot of access to medical journals, I will send any interesting material I find your way also. Take care, ________________________________ To: Stillsdisease Sent: Saturday, January 10, 2009 2:07:32 AM Subject: Re: Probiotics Question Hi , I have access to a quite a few research databases and try to keep up on the latest studies. I'm sort of twiddling my thumbs here waiting for the FDA to approve Tocilizumab (I'm on prednisone, MTX, and Kineret right now but still flaring). I'll cut and paste below something worth reading. in Maine This was in World Journal of Gastroenterology, April 2008: >>>>Probiotic bacteria, defined as living microorganisms that have beneficial effects on human health, have mostly been studied in the prevention and treatment of different gastrointestinal diseases and allergies. Probiotic products, however, are usually consumed by the general, healthy population but not much is known what kind of effects they have on the immune system in healthy adults. It is not clear how probiotics exert their health effects, but one of the most probable action mechanisms is the modulation of immune responses via the gut's mucosal immune system. This study investigated the immunomodulatory effects of probiotics bacteria in healthy adults. It was found that probiotics have an anti-inflammatory potential seen as a decrease in serum CRP levels and as a reduction in bacteria-induced production of proinflammatory cytokines in peripheral blood mononuclear cells. Understanding of the specific immunomodulatory effects of probiotics may help in designing future probiotics for targeted purposes. As the effects in the present study were investigated in healthy adults, the real impact of probiotics on inflammatory variables warrants further evaluation during inflammatory processes and in individuals suffering from various types of inflammatory or autoimmune diseases.<<< << ### This research was carried out in collaboration with University of Helsinki (Finland), Valio Research Centre (Finland), and the National Public Health Institute (Finland). Part of the study was funded by the Academy of Finland. Reference: Kekkonen RA, Lummela N, Karjalainen H, Latvala S, Tynkkynen S, Järvenpää S, Kautiainen H, Julkunen I, Vapaatalo H, Korpela R. Probiotic intervention has strain-specific anti-inflammatory effects in healthy adults. World J Gastroenterol 2008; 14(13): 2029-2036 http://www.wjgnet. com/1007- 9327/14/2029. aspCorrespondenc e to: Riitta Korpela PhD, Assistant Professor, University of Helsinki, Institute of Biomedicine, Pharmacology, PO Box 63, 00014 University of Helsinki, Finland. riitta.korpela@ valio.fi Telephone: +358-10-3813026 Fax: +358-10-3813019 > > Hi , > > Where did you read info about Probotics? It sounds interesting, I love yogurt, would like to find out more about it. > > Take Care, > > > > > > ____________ _________ _________ __ > > To: Stillsdisease@ yahoogroups. com > Sent: Friday, January 9, 2009 7:11:58 PM > Subject: Probiotics Question > > > Hey gang, > Has anyone tried probiotics for Still's? I've been reading some > interesting stuff on their effect on autoimmune disorders, > particularly lowering CRP and lessening cytokine response. > > Probiotics are the " good " bacteria found in yoghurt, miso, fermented > drinks, etc.; you can also buy probiotic supplements, although they > aren't regulated like a med. > in Maine > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 10, 2009 Report Share Posted January 10, 2009 I have been eating the Activia yogurt every morning for several weeks...I was looking into that too, before my flare up in December.. Diane..42 Hey gang, Has anyone tried probiotics for Still's? I've been reading some interesting stuff on their effect on autoimmune disorders, particularly lowering CRP and lessening cytokine response. Probiotics are the " good " bacteria found in yoghurt, miso, fermented drinks, etc.; you can also buy probiotic supplements, although they aren't regulated like a med. in Maine Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 11, 2009 Report Share Posted January 11, 2009 Hi I did have probiotics in a drink form, they were very pleasant to take, but must admit I didn't find they helped at all, but that doesn't mean that it won't benefit anyone else, as we know we all react differently. Best wishes Joan U.K. Quote Link to comment Share on other sites More sharing options...
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