RE: How long/what dosage for spironolactone to start working?

[Guest guest]

You and i are the same age for 2 days anyway. Spiro worked dramatically

after 2 doses for me, but i went years with severe HTN (160/120) and I was on

5 at once when i started it. what was your

potassium? and did they stop the HCTZ? No one ever looked or

checked for Conns until a cardio did in late 2010

43 yo male PA-C with PA

>Hello All

>

>I've been battling HTN since I was 28. Over the years, one drug after another

failed to provide long term control. Finally multiple drugs have failed. I never

had a doctor who thought to test me for any secondary cause. I'm now 43.

>

>5 years ago I had back surgery to remove a benign tumor from my spine that was

causing back pain. During the workup for that, a lesion was seen on my left

adrenal gland.

>

>Now, in the last year, I've been getting more and more curious about Conns as

my bp continues to go higher. My primary ran a 24-hour urine at my urging which

showed aldosterone of 24 which was above their lab normal of 21. No renin was

done.

>

>My primary sent me for a CT to check on the tumor. It is a 2cm lesion

consistent with adenoma, per the report.

>Medications up to this point were Micardis 80mg, Clonidine .2 3times/day, HCTZ

12.5/day

>Bp is running generally in the mid 160s/ low 100s with occasions where it will

shoot up a lot higher.

>

>I finally saw an Endocrinologist who ran the ARR test (because I insisted) and

my Aldosterone was 13.4 vs a Renin of .1. The blood was drawn around 10:30am

fasting. No medications were stopped or changed. It seems this is a normal Aldo

but the ratio of some 134:1 would seem a positive result. The endo did not seem

interested in pursuing treatment for me or doing additional testing.

>

>I've also seen a nephrologist recently who suspected Conn's and put me on

spironolactone 25mg/day and increased my hctz to 50mg/day. There seems to be a

slight benefit since adding the spiro (it's been two weeks) but not a lot. I

called the docs office about increasing the spiro but they've put me on

amlodipine 10mg instead which I just started today.

>

>For those of you on spironolactone, how long did it take to work and at what

dosage?

>

>I've got another appointment with a different endo in early June so I'm hoping

for the best.

>

>Thank you for this great site. It is a wonderful resource.

>

>

[Guest guest]

Very similar to my situation...in my case:

Micardis=totally useless

HCTZ was killing me so switched to less damaginf Indapamide

Norvasc does some lowering of bp helping Spiro

after 7 years of drug combos finally Spiro 100 mg/d normalized my PA BP

Clonidine is useless

with ARR =134 if doc says u r no PA then change your doc..or ask Trump to check his medical credentials!

4-6 weeks for Spiro to fully normalize BP is normal.,,but may need increase it

Max.

61M L adenoma by NP59 scan. High aldos not low renin. med combo #75={Spiro=100, Amlo=10, Indap=2.5, Ramip=5, Metf=1000, Prav=40, Feno=67, K.Cl=120 mEq}{sideEffects: gynecodynia, dry legs skin}{K=4.5}{not DASHing but low-salt diet}

|||Hello All||I've been battling HTN since I was 28. Over the years, one|drug after another failed to provide long term control.|Finally multiple drugs have failed. I never had a doctor who|thought to test me for any secondary cause. I'm now 43.||5 years ago I had back surgery to remove a benign tumor from|my spine that was causing back pain. During the workup for|that, a lesion was seen on my left adrenal gland.||Now, in the last year, I've been getting more and more curious|about Conns as my bp continues to go higher. My primary ran a|24-hour urine at my urging which showed aldosterone of 24|which was above their lab normal of 21. No renin was done.||My primary sent me for a CT to check on the tumor. It is a 2cm|lesion consistent with adenoma, per the report. Medications up|to this point were Micardis 80mg, Clonidine .2 3times/day,|HCTZ 12.5/day Bp is running generally in the mid 160s/ low|100s with occasions where it will shoot up a lot higher.||I finally saw an Endocrinologist who ran the ARR test (because|I insisted) and my Aldosterone was 13.4 vs a Renin of .1. The|blood was drawn around 10:30am fasting. No medications were|stopped or changed. It seems this is a normal Aldo but the|ratio of some 134:1 would seem a positive result. The endo did|not seem interested in pursuing treatment for me or doing|additional testing.||I've also seen a nephrologist recently who suspected Conn's|and put me on spironolactone 25mg/day and increased my hctz to|50mg/day. There seems to be a slight benefit since adding the|spiro (it's been two weeks) but not a lot. I called the docs|office about increasing the spiro but they've put me on|amlodipine 10mg instead which I just started today.||For those of you on spironolactone, how long did it take to|work and at what dosage?||I've got another appointment with a different endo in early|June so I'm hoping for the best.||Thank you for this great site. It is a wonderful resource.||

[Guest guest]

Somebody

should get serious about pursuing treatment because running a BP of 160 for

years is going to be very harmful.

What about your potassium (K)?

Val

On Mon May 16th, 2011 10:47 PM CDT johnster999

wrote:

>Hello All

>

>I've been battling HTN since I was 28. Over the years, one drug after another

failed to provide long term control. Finally multiple drugs have failed. I

never had a doctor who thought to test me for any secondary cause. I'm now 43.

>

>5 years ago I had back surgery to remove a benign tumor from my spine that

was causing back pain. During the workup for that, a lesion was seen on my left

adrenal gland.

>

>Now, in the last year, I've been getting more and more curious about Conns

as my bp continues to go higher. My primary ran a 24-hour urine at my urging

which showed aldosterone of 24 which was above their lab normal of 21. No renin

was done.

>

>My primary sent me for a CT to check on the tumor. It is a 2cm lesion

consistent with adenoma, per the report.

>Medications up to this point were Micardis 80mg, Clonidine .2 3times/day, HCTZ

12.5/day

>Bp is running generally in the mid 160s/ low 100s with occasions where it

will shoot up a lot higher.

>

>I finally saw an Endocrinologist who ran the ARR test (because I insisted)

and my Aldosterone was 13.4 vs a Renin of .1. The blood was drawn around

10:30am fasting. No medications were stopped or changed. It seems this is a

normal Aldo but the ratio of some 134:1 would seem a positive result. The endo

did not seem interested in pursuing treatment for me or doing additional

testing.

>

>I've also seen a nephrologist recently who suspected Conn's and put me on

spironolactone 25mg/day and increased my hctz to 50mg/day. There seems to be a

slight benefit since adding the spiro (it's been two weeks) but not a lot. I

called the docs office about increasing the spiro but they've put me on

amlodipine 10mg instead which I just started today.

>

>For those of you on spironolactone, how long did it take to work and at

what dosage?

>

>I've got another appointment with a different endo in early June so I'm hoping

for the best.

>

>Thank you for this great site. It is a wonderful resource.

>

>

[Guest guest]

Hi.

For me around 10 days and it worked.

However you really need to check the bravo study on the documents part of this

group.

The secret is not much the spiro, the " secret " is to Dash, you need to change

your diet.

Basically that study says this:

We got a bounch of patients we let them eat as much salt as they wanted, and

gave them spiro, even with SUPER HIGH doses of spiro their Blood pressure was

VERY HIGH.

So spiro with high doses of salt does nothing.

Then they grabbed the same patients and restricted their sodium intake, ( they

lowered the amount of salt they used ), all of them had to lower their dose of

spiro, because it was working so good, some did not even need the spiro at the

end.

So really, Unless you start lowering your sodium intake, Spiro could do nothing

at all, or take weeks or months to start.

My personal experience is that I started at 50mgs of spiro, and dashing, now

that dashing is easier and harder, I'm at 6.25mg of spiro and my BP is LOW, very

low.

So really regarless of tests and anything take your spiro and diet, you will do

much better even if you do not have PA.

your body can't raise your BP without you having sodium inside.

Good luck !

o.

>

> Hello All

>

> I've been battling HTN since I was 28. Over the years, one drug after another

failed to provide long term control. Finally multiple drugs have failed. I never

had a doctor who thought to test me for any secondary cause. I'm now 43.

>

> 5 years ago I had back surgery to remove a benign tumor from my spine that was

causing back pain. During the workup for that, a lesion was seen on my left

adrenal gland.

>

> Now, in the last year, I've been getting more and more curious about Conns as

my bp continues to go higher. My primary ran a 24-hour urine at my urging which

showed aldosterone of 24 which was above their lab normal of 21. No renin was

done.

>

> My primary sent me for a CT to check on the tumor. It is a 2cm lesion

consistent with adenoma, per the report.

> Medications up to this point were Micardis 80mg, Clonidine .2 3times/day, HCTZ

12.5/day

> Bp is running generally in the mid 160s/ low 100s with occasions where it will

shoot up a lot higher.

>

> I finally saw an Endocrinologist who ran the ARR test (because I insisted) and

my Aldosterone was 13.4 vs a Renin of .1. The blood was drawn around 10:30am

fasting. No medications were stopped or changed. It seems this is a normal Aldo

but the ratio of some 134:1 would seem a positive result. The endo did not seem

interested in pursuing treatment for me or doing additional testing.

>

> I've also seen a nephrologist recently who suspected Conn's and put me on

spironolactone 25mg/day and increased my hctz to 50mg/day. There seems to be a

slight benefit since adding the spiro (it's been two weeks) but not a lot. I

called the docs office about increasing the spiro but they've put me on

amlodipine 10mg instead which I just started today.

>

> For those of you on spironolactone, how long did it take to work and at what

dosage?

>

> I've got another appointment with a different endo in early June so I'm hoping

for the best.

>

> Thank you for this great site. It is a wonderful resource.

>

[Guest guest]

True,

assuming the HTN is a result of PA.

Val

From: hyperaldosteronism

[mailto:hyperaldosteronism ] On Behalf Of Clarence Grim

AS Dr. G says no salt no hypertension.

CE

Grim MD

On

May 17, 2011, at 2:29 AM, oS wrote:

For me around 10 days and it worked.

However you really need to check the bravo study on the documents part of this

group.

The secret is not much the spiro, the " secret " is to Dash, you need

to change your diet.

Basically that study says this:

We got a bounch of patients we let them eat as much salt as they wanted, and

gave them spiro, even with SUPER HIGH doses of spiro their Blood pressure was

VERY HIGH.

So spiro with high doses of salt does nothing.

Then they grabbed the same patients and restricted their sodium intake, ( they

lowered the amount of salt they used ), all of them had to lower their dose of

spiro, because it was working so good, some did not even need the spiro at the

end.

So really, Unless you start lowering your sodium intake, Spiro could do nothing

at all, or take weeks or months to start.

My personal experience is that I started at 50mgs of spiro, and dashing, now

that dashing is easier and harder, I'm at 6.25mg of spiro and my BP is LOW,

very low.

So really regarless of tests and anything take your spiro and diet, you will do

much better even if you do not have PA.

your body can't raise your BP without you having sodium inside.

Good luck !

o.

[Guest guest]

Hello!

I just wanted to let you know I saw results with Spiro immediately.

I am on 100mg in the morning and 50 mg in the evening. Prior to this

I was on Dyazide (water pill) for hand and feet swelling. After the

second time in the hospital for low K, high HTN the doctor told me

to stop taking that immediately. I wasn't happy with that but I did

it and now since joining this group I am wondering if that

contributed to my problems.

Hope that helps.

Kellie

Female – Age 41

– Height: 5’5”

– Weight since HTN and Low K at all time high of 190.Treated for

HTN from age

18-32 when it suddenly dropped. Started HCTZ for swelling in

04’. Have not

tested positive for PA however the treatment of Spiro is keeping

both HTN and K

in check. No tumor on adrenal gland. Insulin

resistant-Hypoglycemic-No testing

of AVS. Meds: 100 mg of spiro in the morning and 50 mg in the

evening.

Xanax: .5 mg three times a day. DASHING

MRI revealed benign tumor in left eye socket

Hello All

I've been battling HTN since I was 28. Over the years, one

drug after another failed to provide long term control.

Finally multiple drugs have failed. I never had a doctor

who thought to test me for any secondary cause. I'm now

43.

5 years ago I had back surgery to remove a benign tumor

from my spine that was causing back pain. During the

workup for that, a lesion was seen on my left adrenal

gland.

Now, in the last year, I've been getting more and more

curious about Conns as my bp continues to go higher. My

primary ran a 24-hour urine at my urging which showed

aldosterone of 24 which was above their lab normal of 21.

No renin was done.

My primary sent me for a CT to check on the tumor. It is a

2cm lesion consistent with adenoma, per the report.

Medications up to this point were Micardis 80mg, Clonidine

..2 3times/day, HCTZ 12.5/day

Bp is running generally in the mid 160s/ low 100s with

occasions where it will shoot up a lot higher.

I finally saw an Endocrinologist who ran the ARR test

(because I insisted) and my Aldosterone was 13.4 vs a

Renin of .1. The blood was drawn around 10:30am fasting.

No medications were stopped or changed. It seems this is a

normal Aldo but the ratio of some 134:1 would seem a

positive result. The endo did not seem interested in

pursuing treatment for me or doing additional testing.

I've also seen a nephrologist recently who suspected

Conn's and put me on spironolactone 25mg/day and increased

my hctz to 50mg/day. There seems to be a slight benefit

since adding the spiro (it's been two weeks) but not a

lot. I called the docs office about increasing the spiro

but they've put me on amlodipine 10mg instead which I just

started today.

For those of you on spironolactone, how long did it take

to work and at what dosage?

I've got another appointment with a different endo in

early June so I'm hoping for the best.

Thank you for this great site. It is a wonderful resource.

[Guest guest]

I'd say that's a pretty good guess that the dyazide added to your problems. It

contains HCTZ, which is notorious for lowering K.

I took HCTZ for 3 or 4 years, and had constant problems with hands and feet

swelling during that time. I stopped taking it when my PA diagnosis was just

starting - within 2 weeks I had dropped almost 10 pounds in salt/water weight

and have not had any issues with swollen hands and feet since.

My K is still low all the time though, even with the horse pills

> >

> > Hello All

> >

> > I've been battling HTN since I was 28. Over the years, one drug after

> > another failed to provide long term control. Finally multiple drugs

> > have failed. I never had a doctor who thought to test me for any

> > secondary cause. I'm now 43.

> >

> > 5 years ago I had back surgery to remove a benign tumor from my spine

> > that was causing back pain. During the workup for that, a lesion was

> > seen on my left adrenal gland.

> >

> > Now, in the last year, I've been getting more and more curious about

> > Conns as my bp continues to go higher. My primary ran a 24-hour urine

> > at my urging which showed aldosterone of 24 which was above their lab

> > normal of 21. No renin was done.

> >

> > My primary sent me for a CT to check on the tumor. It is a 2cm lesion

> > consistent with adenoma, per the report.

> > Medications up to this point were Micardis 80mg, Clonidine .2

> > 3times/day, HCTZ 12.5/day

> > Bp is running generally in the mid 160s/ low 100s with occasions where

> > it will shoot up a lot higher.

> >

> > I finally saw an Endocrinologist who ran the ARR test (because I

> > insisted) and my Aldosterone was 13.4 vs a Renin of .1. The blood was

> > drawn around 10:30am fasting. No medications were stopped or changed.

> > It seems this is a normal Aldo but the ratio of some 134:1 would seem

> > a positive result. The endo did not seem interested in pursuing

> > treatment for me or doing additional testing.

> >

> > I've also seen a nephrologist recently who suspected Conn's and put me

> > on spironolactone 25mg/day and increased my hctz to 50mg/day. There

> > seems to be a slight benefit since adding the spiro (it's been two

> > weeks) but not a lot. I called the docs office about increasing the

> > spiro but they've put me on amlodipine 10mg instead which I just

> > started today.

> >

> > For those of you on spironolactone, how long did it take to work and

> > at what dosage?

> >

> > I've got another appointment with a different endo in early June so

> > I'm hoping for the best.

> >

> > Thank you for this great site. It is a wonderful resource.

> >

> >

>

[Guest guest]

Stopping Dyazide helped lot I suspect what meds were you on when feet were swelling. Tiped sad Send form miiPhone ;-)May your pressure be low!CE Grim MDSpecializing in DifficultHypertension

Hello!

I just wanted to let you know I saw results with Spiro immediately.

I am on 100mg in the morning and 50 mg in the evening. Prior to this

I was on Dyazide (water pill) for hand and feet swelling. After the

second time in the hospital for low K, high HTN the doctor told me

to stop taking that immediately. I wasn't happy with that but I did

it and now since joining this group I am wondering if that

contributed to my problems.

Hope that helps.

Kellie

Female – Age 41

– Height: 5’5â€

– Weight since HTN and Low K at all time high of 190.Treated for

HTN from age

18-32 when it suddenly dropped. Started HCTZ for swelling in

04’. Have not

tested positive for PA however the treatment of Spiro is keeping

both HTN and K

in check. No tumor on adrenal gland. Insulin

resistant-Hypoglycemic-No testing

of AVS. Meds: 100 mg of spiro in the morning and 50 mg in the

evening.

Xanax: .5 mg three times a day. DASHING

MRI revealed benign tumor in left eye socket

Hello All

I've been battling HTN since I was 28. Over the years, one

drug after another failed to provide long term control.

Finally multiple drugs have failed. I never had a doctor

who thought to test me for any secondary cause. I'm now

43.

5 years ago I had back surgery to remove a benign tumor

from my spine that was causing back pain. During the

workup for that, a lesion was seen on my left adrenal

gland.

Now, in the last year, I've been getting more and more

curious about Conns as my bp continues to go higher. My

primary ran a 24-hour urine at my urging which showed

aldosterone of 24 which was above their lab normal of 21.

No renin was done.

My primary sent me for a CT to check on the tumor. It is a

2cm lesion consistent with adenoma, per the report.

Medications up to this point were Micardis 80mg, Clonidine

..2 3times/day, HCTZ 12.5/day

Bp is running generally in the mid 160s/ low 100s with

occasions where it will shoot up a lot higher.

I finally saw an Endocrinologist who ran the ARR test

(because I insisted) and my Aldosterone was 13.4 vs a

Renin of .1. The blood was drawn around 10:30am fasting.

No medications were stopped or changed. It seems this is a

normal Aldo but the ratio of some 134:1 would seem a

positive result. The endo did not seem interested in

pursuing treatment for me or doing additional testing.

I've also seen a nephrologist recently who suspected

Conn's and put me on spironolactone 25mg/day and increased

my hctz to 50mg/day. There seems to be a slight benefit

since adding the spiro (it's been two weeks) but not a

lot. I called the docs office about increasing the spiro

but they've put me on amlodipine 10mg instead which I just

started today.

For those of you on spironolactone, how long did it take

to work and at what dosage?

I've got another appointment with a different endo in

early June so I'm hoping for the best.

Thank you for this great site. It is a wonderful resource.

[Guest guest]

You need to DASH MORE Tiped sad Send form miiPhone ;-)May your pressure be low!CE Grim MDSpecializing in DifficultHypertension

I'd say that's a pretty good guess that the dyazide added to your problems. It contains HCTZ, which is notorious for lowering K.

I took HCTZ for 3 or 4 years, and had constant problems with hands and feet swelling during that time. I stopped taking it when my PA diagnosis was just starting - within 2 weeks I had dropped almost 10 pounds in salt/water weight and have not had any issues with swollen hands and feet since.

My K is still low all the time though, even with the horse pills

> >

> > Hello All

> >

> > I've been battling HTN since I was 28. Over the years, one drug after

> > another failed to provide long term control. Finally multiple drugs

> > have failed. I never had a doctor who thought to test me for any

> > secondary cause. I'm now 43.

> >

> > 5 years ago I had back surgery to remove a benign tumor from my spine

> > that was causing back pain. During the workup for that, a lesion was

> > seen on my left adrenal gland.

> >

> > Now, in the last year, I've been getting more and more curious about

> > Conns as my bp continues to go higher. My primary ran a 24-hour urine

> > at my urging which showed aldosterone of 24 which was above their lab

> > normal of 21. No renin was done.

> >

> > My primary sent me for a CT to check on the tumor. It is a 2cm lesion

> > consistent with adenoma, per the report.

> > Medications up to this point were Micardis 80mg, Clonidine .2

> > 3times/day, HCTZ 12.5/day

> > Bp is running generally in the mid 160s/ low 100s with occasions where

> > it will shoot up a lot higher.

> >

> > I finally saw an Endocrinologist who ran the ARR test (because I

> > insisted) and my Aldosterone was 13.4 vs a Renin of .1. The blood was

> > drawn around 10:30am fasting. No medications were stopped or changed.

> > It seems this is a normal Aldo but the ratio of some 134:1 would seem

> > a positive result. The endo did not seem interested in pursuing

> > treatment for me or doing additional testing.

> >

> > I've also seen a nephrologist recently who suspected Conn's and put me

> > on spironolactone 25mg/day and increased my hctz to 50mg/day. There

> > seems to be a slight benefit since adding the spiro (it's been two

> > weeks) but not a lot. I called the docs office about increasing the

> > spiro but they've put me on amlodipine 10mg instead which I just

> > started today.

> >

> > For those of you on spironolactone, how long did it take to work and

> > at what dosage?

> >

> > I've got another appointment with a different endo in early June so

> > I'm hoping for the best.

> >

> > Thank you for this great site. It is a wonderful resource.

> >

> >

>

[Guest guest]

You need to DASH MORE Tiped sad Send form miiPhone ;-)May your pressure be low!CE Grim MDSpecializing in DifficultHypertension

I'd say that's a pretty good guess that the dyazide added to your problems. It contains HCTZ, which is notorious for lowering K.

I took HCTZ for 3 or 4 years, and had constant problems with hands and feet swelling during that time. I stopped taking it when my PA diagnosis was just starting - within 2 weeks I had dropped almost 10 pounds in salt/water weight and have not had any issues with swollen hands and feet since.

My K is still low all the time though, even with the horse pills

> >

> > Hello All

> >

> > I've been battling HTN since I was 28. Over the years, one drug after

> > another failed to provide long term control. Finally multiple drugs

> > have failed. I never had a doctor who thought to test me for any

> > secondary cause. I'm now 43.

> >

> > 5 years ago I had back surgery to remove a benign tumor from my spine

> > that was causing back pain. During the workup for that, a lesion was

> > seen on my left adrenal gland.

> >

> > Now, in the last year, I've been getting more and more curious about

> > Conns as my bp continues to go higher. My primary ran a 24-hour urine

> > at my urging which showed aldosterone of 24 which was above their lab

> > normal of 21. No renin was done.

> >

> > My primary sent me for a CT to check on the tumor. It is a 2cm lesion

> > consistent with adenoma, per the report.

> > Medications up to this point were Micardis 80mg, Clonidine .2

> > 3times/day, HCTZ 12.5/day

> > Bp is running generally in the mid 160s/ low 100s with occasions where

> > it will shoot up a lot higher.

> >

> > I finally saw an Endocrinologist who ran the ARR test (because I

> > insisted) and my Aldosterone was 13.4 vs a Renin of .1. The blood was

> > drawn around 10:30am fasting. No medications were stopped or changed.

> > It seems this is a normal Aldo but the ratio of some 134:1 would seem

> > a positive result. The endo did not seem interested in pursuing

> > treatment for me or doing additional testing.

> >

> > I've also seen a nephrologist recently who suspected Conn's and put me

> > on spironolactone 25mg/day and increased my hctz to 50mg/day. There

> > seems to be a slight benefit since adding the spiro (it's been two

> > weeks) but not a lot. I called the docs office about increasing the

> > spiro but they've put me on amlodipine 10mg instead which I just

> > started today.

> >

> > For those of you on spironolactone, how long did it take to work and

> > at what dosage?

> >

> > I've got another appointment with a different endo in early June so

> > I'm hoping for the best.

> >

> > Thank you for this great site. It is a wonderful resource.

> >

> >

>

[Guest guest]

Sorry Dr G, forgot my sig to remind you which one of the 500+ I am Can't DASH

more because the high-K foods are all the ones that make me violently ill

(causing even further lowered K).

What I need is to have the darned adenoma removed!

- msmith1928

45, female, 5'3 " , 120 lbs, 1cm left adrenal nodule, supine aldosterone

28.5/renin 0.2, potassium <2.9 (when not taking supplements); 25mg spiro caused

gynecomastia; no HTN meds; current meds are 20MEQ K 3x/day, singulair 10mg,

norethindrone .35mg, cyclobenzaprine 5-10mg when needed, fexofenadine 180mg when

needed; low sodium, fructose- and grain-free diet

> > > >

> > > > Hello All

> > > >

> > > > I've been battling HTN since I was 28. Over the years, one drug after

> > > > another failed to provide long term control. Finally multiple drugs

> > > > have failed. I never had a doctor who thought to test me for any

> > > > secondary cause. I'm now 43.

> > > >

> > > > 5 years ago I had back surgery to remove a benign tumor from my spine

> > > > that was causing back pain. During the workup for that, a lesion was

> > > > seen on my left adrenal gland.

> > > >

> > > > Now, in the last year, I've been getting more and more curious about

> > > > Conns as my bp continues to go higher. My primary ran a 24-hour urine

> > > > at my urging which showed aldosterone of 24 which was above their lab

> > > > normal of 21. No renin was done.

> > > >

> > > > My primary sent me for a CT to check on the tumor. It is a 2cm lesion

> > > > consistent with adenoma, per the report.

> > > > Medications up to this point were Micardis 80mg, Clonidine .2

> > > > 3times/day, HCTZ 12.5/day

> > > > Bp is running generally in the mid 160s/ low 100s with occasions where

> > > > it will shoot up a lot higher.

> > > >

> > > > I finally saw an Endocrinologist who ran the ARR test (because I

> > > > insisted) and my Aldosterone was 13.4 vs a Renin of .1. The blood was

> > > > drawn around 10:30am fasting. No medications were stopped or changed.

> > > > It seems this is a normal Aldo but the ratio of some 134:1 would seem

> > > > a positive result. The endo did not seem interested in pursuing

> > > > treatment for me or doing additional testing.

> > > >

> > > > I've also seen a nephrologist recently who suspected Conn's and put me

> > > > on spironolactone 25mg/day and increased my hctz to 50mg/day. There

> > > > seems to be a slight benefit since adding the spiro (it's been two

> > > > weeks) but not a lot. I called the docs office about increasing the

> > > > spiro but they've put me on amlodipine 10mg instead which I just

> > > > started today.

> > > >

> > > > For those of you on spironolactone, how long did it take to work and

> > > > at what dosage?

> > > >

> > > > I've got another appointment with a different endo in early June so

> > > > I'm hoping for the best.

> > > >

> > > > Thank you for this great site. It is a wonderful resource.

> > > >

> > > >

> > >

> >

> >

>

[Guest guest]

Sorry Dr G, forgot my sig to remind you which one of the 500+ I am Can't DASH

more because the high-K foods are all the ones that make me violently ill

(causing even further lowered K).

What I need is to have the darned adenoma removed!

- msmith1928

45, female, 5'3 " , 120 lbs, 1cm left adrenal nodule, supine aldosterone

28.5/renin 0.2, potassium <2.9 (when not taking supplements); 25mg spiro caused

gynecomastia; no HTN meds; current meds are 20MEQ K 3x/day, singulair 10mg,

norethindrone .35mg, cyclobenzaprine 5-10mg when needed, fexofenadine 180mg when

needed; low sodium, fructose- and grain-free diet

> > > >

> > > > Hello All

> > > >

> > > > I've been battling HTN since I was 28. Over the years, one drug after

> > > > another failed to provide long term control. Finally multiple drugs

> > > > have failed. I never had a doctor who thought to test me for any

> > > > secondary cause. I'm now 43.

> > > >

> > > > 5 years ago I had back surgery to remove a benign tumor from my spine

> > > > that was causing back pain. During the workup for that, a lesion was

> > > > seen on my left adrenal gland.

> > > >

> > > > Now, in the last year, I've been getting more and more curious about

> > > > Conns as my bp continues to go higher. My primary ran a 24-hour urine

> > > > at my urging which showed aldosterone of 24 which was above their lab

> > > > normal of 21. No renin was done.

> > > >

> > > > My primary sent me for a CT to check on the tumor. It is a 2cm lesion

> > > > consistent with adenoma, per the report.

> > > > Medications up to this point were Micardis 80mg, Clonidine .2

> > > > 3times/day, HCTZ 12.5/day

> > > > Bp is running generally in the mid 160s/ low 100s with occasions where

> > > > it will shoot up a lot higher.

> > > >

> > > > I finally saw an Endocrinologist who ran the ARR test (because I

> > > > insisted) and my Aldosterone was 13.4 vs a Renin of .1. The blood was

> > > > drawn around 10:30am fasting. No medications were stopped or changed.

> > > > It seems this is a normal Aldo but the ratio of some 134:1 would seem

> > > > a positive result. The endo did not seem interested in pursuing

> > > > treatment for me or doing additional testing.

> > > >

> > > > I've also seen a nephrologist recently who suspected Conn's and put me

> > > > on spironolactone 25mg/day and increased my hctz to 50mg/day. There

> > > > seems to be a slight benefit since adding the spiro (it's been two

> > > > weeks) but not a lot. I called the docs office about increasing the

> > > > spiro but they've put me on amlodipine 10mg instead which I just

> > > > started today.

> > > >

> > > > For those of you on spironolactone, how long did it take to work and

> > > > at what dosage?

> > > >

> > > > I've got another appointment with a different endo in early June so

> > > > I'm hoping for the best.

> > > >

> > > > Thank you for this great site. It is a wonderful resource.

> > > >

> > > >

> > >

> >

> >

>

[Guest guest]

Dyazide = HCTZ + Triamterene

HCTZ = the killer drug

Triamterene = 30% potency of Spiro

Based on my understanding Ltd.

Max.

Hello!I just wanted to let you know I saw results with Spiro immediately. I am on 100mg in the morning and 50 mg in the evening. Prior to this I was on Dyazide (water pill) for hand and feet swelling. After the second time in the hospital for low K, high HTN the doctor told me to stop taking that immediately. I wasn't happy with that but I did it and now since joining this group I am wondering if that contributed to my problems.Hope that helps.Kellie

Female – Age 41 – Height: 5’5” – Weight since HTN and Low K at all time high of 190.Treated for HTN from age 18-32 when it suddenly dropped. Started HCTZ for swelling in 04’. Have not tested positive for PA however the treatment of Spiro is keeping both HTN and K in check. No tumor on adrenal gland. Insulin resistant-Hypoglycemic-No testing of AVS. Meds: 100 mg of spiro in the morning and 50 mg in the evening. Xanax: .5 mg three times a day. DASHINGMRI revealed benign tumor in left eye socket

[Guest guest]

Dyazide = HCTZ + Triamterene

HCTZ = the killer drug

Triamterene = 30% potency of Spiro

Based on my understanding Ltd.

Max.

Hello!I just wanted to let you know I saw results with Spiro immediately. I am on 100mg in the morning and 50 mg in the evening. Prior to this I was on Dyazide (water pill) for hand and feet swelling. After the second time in the hospital for low K, high HTN the doctor told me to stop taking that immediately. I wasn't happy with that but I did it and now since joining this group I am wondering if that contributed to my problems.Hope that helps.Kellie

Female – Age 41 – Height: 5’5” – Weight since HTN and Low K at all time high of 190.Treated for HTN from age 18-32 when it suddenly dropped. Started HCTZ for swelling in 04’. Have not tested positive for PA however the treatment of Spiro is keeping both HTN and K in check. No tumor on adrenal gland. Insulin resistant-Hypoglycemic-No testing of AVS. Meds: 100 mg of spiro in the morning and 50 mg in the evening. Xanax: .5 mg three times a day. DASHINGMRI revealed benign tumor in left eye socket

[Guest guest]

So now I can't help but wonder if I never took HCTZ if I would be in

this boat!! I try to tell myself that wasn't the cause since i

suffered high HTN starting at age 19 and horrible migraines through

my 30's before I even took the HCTZ.

Unlike you though I gained 10+ pounds after quitting HCTZ; however,

I don't have the swelling of the hands and feet anymore probably due

to cutting out the salt.

I'd say that's a pretty good guess that the dyazide added

to your problems. It contains HCTZ, which is notorious for

lowering K.

I took HCTZ for 3 or 4 years, and had constant problems

with hands and feet swelling during that time. I stopped

taking it when my PA diagnosis was just starting - within

2 weeks I had dropped almost 10 pounds in salt/water

weight and have not had any issues with swollen hands and

feet since.

My K is still low all the time though, even with the horse

pills

> >

> > Hello All

> >

> > I've been battling HTN since I was 28. Over the

years, one drug after

> > another failed to provide long term control.

Finally multiple drugs

> > have failed. I never had a doctor who thought to

test me for any

> > secondary cause. I'm now 43.

> >

> > 5 years ago I had back surgery to remove a

benign tumor from my spine

> > that was causing back pain. During the workup

for that, a lesion was

> > seen on my left adrenal gland.

> >

> > Now, in the last year, I've been getting more

and more curious about

> > Conns as my bp continues to go higher. My

primary ran a 24-hour urine

> > at my urging which showed aldosterone of 24

which was above their lab

> > normal of 21. No renin was done.

> >

> > My primary sent me for a CT to check on the

tumor. It is a 2cm lesion

> > consistent with adenoma, per the report.

> > Medications up to this point were Micardis 80mg,

Clonidine .2

> > 3times/day, HCTZ 12.5/day

> > Bp is running generally in the mid 160s/ low

100s with occasions where

> > it will shoot up a lot higher.

> >

> > I finally saw an Endocrinologist who ran the ARR

test (because I

> > insisted) and my Aldosterone was 13.4 vs a Renin

of .1. The blood was

> > drawn around 10:30am fasting. No medications

were stopped or changed.

> > It seems this is a normal Aldo but the ratio of

some 134:1 would seem

> > a positive result. The endo did not seem

interested in pursuing

> > treatment for me or doing additional testing.

> >

> > I've also seen a nephrologist recently who

suspected Conn's and put me

> > on spironolactone 25mg/day and increased my hctz

to 50mg/day. There

> > seems to be a slight benefit since adding the

spiro (it's been two

> > weeks) but not a lot. I called the docs office

about increasing the

> > spiro but they've put me on amlodipine 10mg

instead which I just

> > started today.

> >

> > For those of you on spironolactone, how long did

it take to work and

> > at what dosage?

> >

> > I've got another appointment with a different

endo in early June so

> > I'm hoping for the best.

> >

> > Thank you for this great site. It is a wonderful

resource.

> >

> >

>

[Guest guest]

I was on no medications when the hands and feet started swelling.

That was after my blood pressure dropped for now reason after having

high HTN from age 19-32.  The swelling started about 2 years after

that.

 

Stopping Dyazide helped lot I suspect what meds were

you on when feet were swelling. 

Tiped sad Send form mi

iPhone ;-)

May your pressure be low!

CE Grim MD

Specializing in Difficult

Hypertension

On May 17, 2011, at 6:27 PM, Kellie

wrote:

 

Hello!

I just wanted to let you know I saw results with

Spiro immediately.  I am on 100mg in the morning and

50 mg in the evening. Prior to this I was on Dyazide

(water pill) for hand and feet swelling. After the

second time in the hospital for low K, high HTN the

doctor told me to stop taking that immediately. I

wasn't happy with that but I did it and now since

joining this group I am wondering if that

contributed to my problems.

Hope that helps.

Kellie

Female

– Age 41 – Height: 5’5†– Weight since HTN and Low

K at all time high of 190.Treated for HTN from age

18-32 when it suddenly dropped. Started HCTZ for

swelling in 04’. Have not tested positive for PA

however the treatment of Spiro is keeping both HTN

and K in check. No tumor on adrenal gland. Insulin

resistant-Hypoglycemic-No testing of AVS. Meds: 

100 mg of spiro in the morning and 50 mg in the

evening. Xanax: .5 mg three times a day.  DASHING

MRI revealed benign tumor in left eye socket

 

Hello All

I've been battling HTN since I was 28. Over the

years, one drug after another failed to provide

long term control. Finally multiple drugs have

failed. I never had a doctor who thought to test

me for any secondary cause. I'm now 43.

5 years ago I had back surgery to remove a

benign tumor from my spine that was causing back

pain. During the workup for that, a lesion was

seen on my left adrenal gland.

Now, in the last year, I've been getting more

and more curious about Conns as my bp continues

to go higher. My primary ran a 24-hour urine at

my urging which showed aldosterone of 24 which

was above their lab normal of 21. No renin was

done.

My primary sent me for a CT to check on the

tumor. It is a 2cm lesion consistent with

adenoma, per the report.

Medications up to this point were Micardis 80mg,

Clonidine .2 3times/day, HCTZ 12.5/day

Bp is running generally in the mid 160s/ low

100s with occasions where it will shoot up a lot

higher.

I finally saw an Endocrinologist who ran the ARR

test (because I insisted) and my Aldosterone was

13.4 vs a Renin of .1. The blood was drawn

around 10:30am fasting. No medications were

stopped or changed. It seems this is a normal

Aldo but the ratio of some 134:1 would seem a

positive result. The endo did not seem

interested in pursuing treatment for me or doing

additional testing.

I've also seen a nephrologist recently who

suspected Conn's and put me on spironolactone

25mg/day and increased my hctz to 50mg/day.

There seems to be a slight benefit since adding

the spiro (it's been two weeks) but not a lot. I

called the docs office about increasing the

spiro but they've put me on amlodipine 10mg

instead which I just started today.

For those of you on spironolactone, how long did

it take to work and at what dosage?

I've got another appointment with a different

endo in early June so I'm hoping for the best.

Thank you for this great site. It is a wonderful

resource.

[Guest guest]

Wish I had known that back then!

Dyazide = HCTZ +

Triamterene

HCTZ = the killer drug

Triamterene = 30% potency

of Spiro

Based on my understanding

Ltd.

Max.

Hello!

I just wanted to let you know I saw results with Spiro

immediately. I am on 100mg in the morning and 50 mg in

the evening. Prior to this I was on Dyazide (water pill)

for hand and feet swelling. After the second time in the

hospital for low K, high HTN the doctor told me to stop

taking that immediately. I wasn't happy with that but I

did it and now since joining this group I am wondering if

that contributed to my problems.

Hope that helps.

Kellie

Female

– Age 41 – Height: 5’5” – Weight since HTN and Low K

at all time high of 190.Treated for HTN from age 18-32

when it suddenly dropped. Started HCTZ for swelling in

04’. Have not tested positive for PA however the

treatment of Spiro is keeping both HTN and K in check.

No tumor on adrenal gland. Insulin

resistant-Hypoglycemic-No testing of AVS. Meds: 100

mg of spiro in the morning and 50 mg in the evening.

Xanax: .5 mg three times a day. DASHING

MRI revealed benign tumor in left eye socket

[Guest guest]

Hi Val

My K is running about 3.0 to 3.2 on 8 meq supplements 3 times daily.

Over the last few years I've had a variety of unspecific symptoms I now realize

were probably low K. Aches in the chest, weird sensations in the hands and

feet,twitching eyelids, etc.

>

> >Hello All

> >

> >I've been battling HTN since I was 28. Over the years, one drug after

> another failed to provide long term control. Finally multiple drugs have

> failed. I never had a doctor who thought to test me for any secondary cause.

> I'm now 43.

> >

> >5 years ago I had back surgery to remove a benign tumor from my spine that

> was causing back pain. During the workup for that, a lesion was seen on my

> left adrenal gland.

> >

> >Now, in the last year, I've been getting more and more curious about Conns

> as my bp continues to go higher. My primary ran a 24-hour urine at my urging

> which showed aldosterone of 24 which was above their lab normal of 21. No

> renin was done.

> >

> >My primary sent me for a CT to check on the tumor. It is a 2cm lesion

> consistent with adenoma, per the report.

> >Medications up to this point were Micardis 80mg, Clonidine .2 3times/day,

> HCTZ 12.5/day

> >Bp is running generally in the mid 160s/ low 100s with occasions where it

> will shoot up a lot higher.

> >

> >I finally saw an Endocrinologist who ran the ARR test (because I insisted)

> and my Aldosterone was 13.4 vs a Renin of .1. The blood was drawn around

> 10:30am fasting. No medications were stopped or changed. It seems this is a

> normal Aldo but the ratio of some 134:1 would seem a positive result. The

> endo did not seem interested in pursuing treatment for me or doing

> additional testing.

> >

> >I've also seen a nephrologist recently who suspected Conn's and put me on

> spironolactone 25mg/day and increased my hctz to 50mg/day. There seems to be

> a slight benefit since adding the spiro (it's been two weeks) but not a lot.

> I called the docs office about increasing the spiro but they've put me on

> amlodipine 10mg instead which I just started today.

> >

> >For those of you on spironolactone, how long did it take to work and at

> what dosage?

> >

> >I've got another appointment with a different endo in early June so I'm

> hoping for the best.

> >

> >Thank you for this great site. It is a wonderful resource.

> >

> >

>

[Guest guest]

First u want to know if surgery will help. Tiped sad Send form miiPhone ;-)May your pressure be low!CE Grim MDSpecializing in DifficultHypertension

Sorry Dr G, forgot my sig to remind you which one of the 500+ I am Can't DASH more because the high-K foods are all the ones that make me violently ill (causing even further lowered K).

What I need is to have the darned adenoma removed!

- msmith1928

45, female, 5'3", 120 lbs, 1cm left adrenal nodule, supine aldosterone 28.5/renin 0.2, potassium <2.9 (when not taking supplements); 25mg spiro caused gynecomastia; no HTN meds; current meds are 20MEQ K 3x/day, singulair 10mg, norethindrone .35mg, cyclobenzaprine 5-10mg when needed, fexofenadine 180mg when needed; low sodium, fructose- and grain-free diet

> > > >

> > > > Hello All

> > > >

> > > > I've been battling HTN since I was 28. Over the years, one drug after

> > > > another failed to provide long term control. Finally multiple drugs

> > > > have failed. I never had a doctor who thought to test me for any

> > > > secondary cause. I'm now 43.

> > > >

> > > > 5 years ago I had back surgery to remove a benign tumor from my spine

> > > > that was causing back pain. During the workup for that, a lesion was

> > > > seen on my left adrenal gland.

> > > >

> > > > Now, in the last year, I've been getting more and more curious about

> > > > Conns as my bp continues to go higher. My primary ran a 24-hour urine

> > > > at my urging which showed aldosterone of 24 which was above their lab

> > > > normal of 21. No renin was done.

> > > >

> > > > My primary sent me for a CT to check on the tumor. It is a 2cm lesion

> > > > consistent with adenoma, per the report.

> > > > Medications up to this point were Micardis 80mg, Clonidine .2

> > > > 3times/day, HCTZ 12.5/day

> > > > Bp is running generally in the mid 160s/ low 100s with occasions where

> > > > it will shoot up a lot higher.

> > > >

> > > > I finally saw an Endocrinologist who ran the ARR test (because I

> > > > insisted) and my Aldosterone was 13.4 vs a Renin of .1. The blood was

> > > > drawn around 10:30am fasting. No medications were stopped or changed.

> > > > It seems this is a normal Aldo but the ratio of some 134:1 would seem

> > > > a positive result. The endo did not seem interested in pursuing

> > > > treatment for me or doing additional testing.

> > > >

> > > > I've also seen a nephrologist recently who suspected Conn's and put me

> > > > on spironolactone 25mg/day and increased my hctz to 50mg/day. There

> > > > seems to be a slight benefit since adding the spiro (it's been two

> > > > weeks) but not a lot. I called the docs office about increasing the

> > > > spiro but they've put me on amlodipine 10mg instead which I just

> > > > started today.

> > > >

> > > > For those of you on spironolactone, how long did it take to work and

> > > > at what dosage?

> > > >

> > > > I've got another appointment with a different endo in early June so

> > > > I'm hoping for the best.

> > > >

> > > > Thank you for this great site. It is a wonderful resource.

> > > >

> > > >

> > >

> >

> >

>

[Guest guest]

Used to be agent of choice it HTN and is still a good one once u know it K after month or so. Tiped sad Send form miiPhone ;-)May your pressure be low!CE Grim MDSpecializing in DifficultHypertension

Dyazide = HCTZ + Triamterene

HCTZ = the killer drug

Triamterene = 30% potency of Spiro

Based on my understanding Ltd.

Max.

Hello!I just wanted to let you know I saw results with Spiro immediately. I am on 100mg in the morning and 50 mg in the evening. Prior to this I was on Dyazide (water pill) for hand and feet swelling. After the second time in the hospital for low K, high HTN the doctor told me to stop taking that immediately. I wasn't happy with that but I did it and now since joining this group I am wondering if that contributed to my problems.Hope that helps.Kellie

Female – Age 41 – Height: 5’5†– Weight since HTN and Low K at all time high of 190.Treated for HTN from age 18-32 when it suddenly dropped. Started HCTZ for swelling in 04’. Have not tested positive for PA however the treatment of Spiro is keeping both HTN and K in check. No tumor on adrenal gland. Insulin resistant-Hypoglycemic-No testing of AVS. Meds: 100 mg of spiro in the morning and 50 mg in the evening. Xanax: .5 mg three times a day. DASHINGMRI revealed benign tumor in left eye socket

[Guest guest]

I know... I'm still waiting for my AVS results to come in. Waiting is hard!

> > > > > >

> > > > > > Hello All

> > > > > >

> > > > > > I've been battling HTN since I was 28. Over the years, one drug

after

> > > > > > another failed to provide long term control. Finally multiple drugs

> > > > > > have failed. I never had a doctor who thought to test me for any

> > > > > > secondary cause. I'm now 43.

> > > > > >

> > > > > > 5 years ago I had back surgery to remove a benign tumor from my

spine

> > > > > > that was causing back pain. During the workup for that, a lesion was

> > > > > > seen on my left adrenal gland.

> > > > > >

> > > > > > Now, in the last year, I've been getting more and more curious about

> > > > > > Conns as my bp continues to go higher. My primary ran a 24-hour

urine

> > > > > > at my urging which showed aldosterone of 24 which was above their

lab

> > > > > > normal of 21. No renin was done.

> > > > > >

> > > > > > My primary sent me for a CT to check on the tumor. It is a 2cm

lesion

> > > > > > consistent with adenoma, per the report.

> > > > > > Medications up to this point were Micardis 80mg, Clonidine .2

> > > > > > 3times/day, HCTZ 12.5/day

> > > > > > Bp is running generally in the mid 160s/ low 100s with occasions

where

> > > > > > it will shoot up a lot higher.

> > > > > >

> > > > > > I finally saw an Endocrinologist who ran the ARR test (because I

> > > > > > insisted) and my Aldosterone was 13.4 vs a Renin of .1. The blood

was

> > > > > > drawn around 10:30am fasting. No medications were stopped or

changed.

> > > > > > It seems this is a normal Aldo but the ratio of some 134:1 would

seem

> > > > > > a positive result. The endo did not seem interested in pursuing

> > > > > > treatment for me or doing additional testing.

> > > > > >

> > > > > > I've also seen a nephrologist recently who suspected Conn's and put

me

> > > > > > on spironolactone 25mg/day and increased my hctz to 50mg/day. There

> > > > > > seems to be a slight benefit since adding the spiro (it's been two

> > > > > > weeks) but not a lot. I called the docs office about increasing the

> > > > > > spiro but they've put me on amlodipine 10mg instead which I just

> > > > > > started today.

> > > > > >

> > > > > > For those of you on spironolactone, how long did it take to work and

> > > > > > at what dosage?

> > > > > >

> > > > > > I've got another appointment with a different endo in early June so

> > > > > > I'm hoping for the best.

> > > > > >

> > > > > > Thank you for this great site. It is a wonderful resource.

> > > > > >

> > > > > >

> > > > >

> > > >

> > > >

> > >

> >

> >

>

[Guest guest]

You

have PA. Are you DASHING? Considering AVS? 25 mg spiro is hardly anything. Unless you getting that aldosterone

blocked, you will have heart/kidney damage. If I remember correctly, amlodipine

will not stop the left ventricular thickening.

Val

From: hyperaldosteronism

[mailto:hyperaldosteronism ] On Behalf Of johnster999

Hi Val

My K is running about 3.0 to 3.2 on 8 meq supplements 3 times daily.

Over the last few years I've had a variety of unspecific symptoms I now realize

were probably low K. Aches in the chest, weird sensations in the hands and

feet,twitching eyelids, etc.

>

> >Hello All

> >

> >I've been battling HTN since I was 28. Over the years, one drug after

> another failed to provide long term control. Finally multiple drugs have

> failed. I never had a doctor who thought to test me for any secondary

cause.

> I'm now 43.

> >

> >5 years ago I had back surgery to remove a benign tumor from my spine

that

> was causing back pain. During the workup for that, a lesion was seen on my

> left adrenal gland.

> >

> >Now, in the last year, I've been getting more and more curious about

Conns

> as my bp continues to go higher. My primary ran a 24-hour urine at my

urging

> which showed aldosterone of 24 which was above their lab normal of 21. No

> renin was done.

> >

> >My primary sent me for a CT to check on the tumor. It is a 2cm lesion

> consistent with adenoma, per the report.

> >Medications up to this point were Micardis 80mg, Clonidine .2

3times/day,

> HCTZ 12.5/day

> >Bp is running generally in the mid 160s/ low 100s with occasions where

it

> will shoot up a lot higher.

> >

> >I finally saw an Endocrinologist who ran the ARR test (because I

insisted)

> and my Aldosterone was 13.4 vs a Renin of .1. The blood was drawn around

> 10:30am fasting. No medications were stopped or changed. It seems this is

a

> normal Aldo but the ratio of some 134:1 would seem a positive result. The

> endo did not seem interested in pursuing treatment for me or doing

> additional testing.

> >

> >I've also seen a nephrologist recently who suspected Conn's and put me

on

> spironolactone 25mg/day and increased my hctz to 50mg/day. There seems to

be

> a slight benefit since adding the spiro (it's been two weeks) but not a

lot.

> I called the docs office about increasing the spiro but they've put me on

> amlodipine 10mg instead which I just started today.

> >

> >For those of you on spironolactone, how long did it take to work and

at

> what dosage?

> >

> >I've got another appointment with a different endo in early June so

I'm

> hoping for the best.

> >

> >Thank you for this great site. It is a wonderful resource.

> >

> >

>

[Guest guest]

Swelling means u were eating more salt than you could get rid of. BCPs?Tiped sad Send form miiPhone ;-)May your pressure be low!CE Grim MDSpecializing in DifficultHypertension

I was on no medications when the hands and feet started swelling.

That was after my blood pressure dropped for now reason after having

high HTN from age 19-32. The swelling started about 2 years after

that.

Stopping Dyazide helped lot I suspect what meds were

you on when feet were swelling.

Tiped sad Send form mi

iPhone ;-)

May your pressure be low!

CE Grim MD

Specializing in Difficult

Hypertension

On May 17, 2011, at 6:27 PM, Kellie

wrote:

Hello!

I just wanted to let you know I saw results with

Spiro immediately. I am on 100mg in the morning and

50 mg in the evening. Prior to this I was on Dyazide

(water pill) for hand and feet swelling. After the

second time in the hospital for low K, high HTN the

doctor told me to stop taking that immediately. I

wasn't happy with that but I did it and now since

joining this group I am wondering if that

contributed to my problems.

Hope that helps.

Kellie

Female

– Age 41 – Height: 5’5†– Weight since HTN and Low

K at all time high of 190.Treated for HTN from age

18-32 when it suddenly dropped. Started HCTZ for

swelling in 04’. Have not tested positive for PA

however the treatment of Spiro is keeping both HTN

and K in check. No tumor on adrenal gland. Insulin

resistant-Hypoglycemic-No testing of AVS. Meds:

100 mg of spiro in the morning and 50 mg in the

evening. Xanax: .5 mg three times a day. DASHING

MRI revealed benign tumor in left eye socket

Hello All

I've been battling HTN since I was 28. Over the

years, one drug after another failed to provide

long term control. Finally multiple drugs have

failed. I never had a doctor who thought to test

me for any secondary cause. I'm now 43.

5 years ago I had back surgery to remove a

benign tumor from my spine that was causing back

pain. During the workup for that, a lesion was

seen on my left adrenal gland.

Now, in the last year, I've been getting more

and more curious about Conns as my bp continues

to go higher. My primary ran a 24-hour urine at

my urging which showed aldosterone of 24 which

was above their lab normal of 21. No renin was

done.

My primary sent me for a CT to check on the

tumor. It is a 2cm lesion consistent with

adenoma, per the report.

Medications up to this point were Micardis 80mg,

Clonidine .2 3times/day, HCTZ 12.5/day

Bp is running generally in the mid 160s/ low

100s with occasions where it will shoot up a lot

higher.

I finally saw an Endocrinologist who ran the ARR

test (because I insisted) and my Aldosterone was

13.4 vs a Renin of .1. The blood was drawn

around 10:30am fasting. No medications were

stopped or changed. It seems this is a normal

Aldo but the ratio of some 134:1 would seem a

positive result. The endo did not seem

interested in pursuing treatment for me or doing

additional testing.

I've also seen a nephrologist recently who

suspected Conn's and put me on spironolactone

25mg/day and increased my hctz to 50mg/day.

There seems to be a slight benefit since adding

the spiro (it's been two weeks) but not a lot. I

called the docs office about increasing the

spiro but they've put me on amlodipine 10mg

instead which I just started today.

For those of you on spironolactone, how long did

it take to work and at what dosage?

I've got another appointment with a different

endo in early June so I'm hoping for the best.

Thank you for this great site. It is a wonderful

resource.

[Guest guest]

Well it is also the best drug we have to prevent stroke etc in run of the mill HTN. Tiped sad Send form miiPhone ;-)May your pressure be low!CE Grim MDSpecializing in DifficultHypertension

Wish I had known that back then!

Dyazide = HCTZ +

Triamterene

HCTZ = the killer drug

Triamterene = 30% potency

of Spiro

Based on my understanding

Ltd.

Max.

Hello!

I just wanted to let you know I saw results with Spiro

immediately. I am on 100mg in the morning and 50 mg in

the evening. Prior to this I was on Dyazide (water pill)

for hand and feet swelling. After the second time in the

hospital for low K, high HTN the doctor told me to stop

taking that immediately. I wasn't happy with that but I

did it and now since joining this group I am wondering if

that contributed to my problems.

Hope that helps.

Kellie

Female

– Age 41 – Height: 5’5†– Weight since HTN and Low K

at all time high of 190.Treated for HTN from age 18-32

when it suddenly dropped. Started HCTZ for swelling in

04’. Have not tested positive for PA however the

treatment of Spiro is keeping both HTN and K in check.

No tumor on adrenal gland. Insulin

resistant-Hypoglycemic-No testing of AVS. Meds: 100

mg of spiro in the morning and 50 mg in the evening.

Xanax: .5 mg three times a day. DASHING

MRI revealed benign tumor in left eye socket

[Guest guest]

8 mEq is nothing you need to DASH WHICH will give you About 120 mM1 cup of low NA V8 will give you ~1000 KTiped sad Send form miiPhone ;-)May your pressure be low!CE Grim MDSpecializing in DifficultHypertension

Hi Val

My K is running about 3.0 to 3.2 on 8 meq supplements 3 times daily.

Over the last few years I've had a variety of unspecific symptoms I now realize were probably low K. Aches in the chest, weird sensations in the hands and feet,twitching eyelids, etc.

>

> >Hello All

> >

> >I've been battling HTN since I was 28. Over the years, one drug after

> another failed to provide long term control. Finally multiple drugs have

> failed. I never had a doctor who thought to test me for any secondary cause.

> I'm now 43.

> >

> >5 years ago I had back surgery to remove a benign tumor from my spine that

> was causing back pain. During the workup for that, a lesion was seen on my

> left adrenal gland.

> >

> >Now, in the last year, I've been getting more and more curious about Conns

> as my bp continues to go higher. My primary ran a 24-hour urine at my urging

> which showed aldosterone of 24 which was above their lab normal of 21. No

> renin was done.

> >

> >My primary sent me for a CT to check on the tumor. It is a 2cm lesion

> consistent with adenoma, per the report.

> >Medications up to this point were Micardis 80mg, Clonidine .2 3times/day,

> HCTZ 12.5/day

> >Bp is running generally in the mid 160s/ low 100s with occasions where it

> will shoot up a lot higher.

> >

> >I finally saw an Endocrinologist who ran the ARR test (because I insisted)

> and my Aldosterone was 13.4 vs a Renin of .1. The blood was drawn around

> 10:30am fasting. No medications were stopped or changed. It seems this is a

> normal Aldo but the ratio of some 134:1 would seem a positive result. The

> endo did not seem interested in pursuing treatment for me or doing

> additional testing.

> >

> >I've also seen a nephrologist recently who suspected Conn's and put me on

> spironolactone 25mg/day and increased my hctz to 50mg/day. There seems to be

> a slight benefit since adding the spiro (it's been two weeks) but not a lot.

> I called the docs office about increasing the spiro but they've put me on

> amlodipine 10mg instead which I just started today.

> >

> >For those of you on spironolactone, how long did it take to work and at

> what dosage?

> >

> >I've got another appointment with a different endo in early June so I'm

> hoping for the best.

> >

> >Thank you for this great site. It is a wonderful resource.

> >

> >

>