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Supine vs Upright PAC for differentiation of APA vs BAH

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I'm reading on the internet that one way to differentiate Adolsterone Producing

Adenomas vs Bilateral Adrenal Hyperplasia is to compare a supine PAC vs an

upright PAC.

The PAC after 4 hours of upright position should be 50% more than the morning

PAC taken after 8 hours of sleep.

Poor man's version, I have one upright reading from February and a supine

reading from May. Different days, different months even, and different

hypertensive meds.

Upright was ~ 36 ng/dL and Supine was ~ 39.5 ng/dL. Morning was actually

greater than afternoon which screams APA.

I will take the data with a grain of salt (har har har); but Do you guys think

I'm crazy to even compare the two? Or is the rise in upright PAC great enough

to cover for the variables?

Thanks,

Honter

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Read more about this test. I think they have to give you some other drug to do

this test.

>

> I'm reading on the internet that one way to differentiate Adolsterone

Producing Adenomas vs Bilateral Adrenal Hyperplasia is to compare a supine PAC

vs an upright PAC.

>

> The PAC after 4 hours of upright position should be 50% more than the morning

PAC taken after 8 hours of sleep.

>

> Poor man's version, I have one upright reading from February and a supine

reading from May. Different days, different months even, and different

hypertensive meds.

>

> Upright was ~ 36 ng/dL and Supine was ~ 39.5 ng/dL. Morning was actually

greater than afternoon which screams APA.

>

> I will take the data with a grain of salt (har har har); but Do you guys think

I'm crazy to even compare the two? Or is the rise in upright PAC great enough

to cover for the variables?

>

> Thanks,

> Honter

>

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Need to be done on same day and carefully timed. We gave up using it about 30 years ago. Tiped sad Send form miiPhone ;-)May your pressure be low!CE Grim MDSpecializing in DifficultHypertension

I'm reading on the internet that one way to differentiate Adolsterone Producing Adenomas vs Bilateral Adrenal Hyperplasia is to compare a supine PAC vs an upright PAC.

The PAC after 4 hours of upright position should be 50% more than the morning PAC taken after 8 hours of sleep.

Poor man's version, I have one upright reading from February and a supine reading from May. Different days, different months even, and different hypertensive meds.

Upright was ~ 36 ng/dL and Supine was ~ 39.5 ng/dL. Morning was actually greater than afternoon which screams APA.

I will take the data with a grain of salt (har har har); but Do you guys think I'm crazy to even compare the two? Or is the rise in upright PAC great enough to cover for the variables?

Thanks,

Honter

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