New guidelines for post-surgical nausea and vomiting

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New guidelines for nausea and vomiting

http://www.news-medical.net/?id=20545

After five years of reviewing the latest research findings, a panel

of experts led by a Duke University Medical Center anesthesiologist

has developed new guidelines to help physicians reduce the

occurrence of nausea and vomiting in patients after surgery.

Despite decades of advances in surgical techniques and improved

anesthetic agents, one out of three patients still experiences

postoperative nausea and vomiting, said Duke anesthesiologist Tong

J. Gan, M.D., leader of the panel that developed the guidelines.

Such conditions not only can lead to patient dissatisfaction, but

also can lengthen hospital stays and prolong recovery, he said.

Gan presented the new guidelines, one set for adults and one for

children, on Monday, Oct. 16, at the annual scientific meeting of

the American Society of Anesthesiologists, in Chicago. The panel,

which included anesthesiologists, surgeons, pharmacists, nurse

anesthetists and biostatisticians, was commissioned and supported by

the Society of Ambulatory Anesthesia.

The guidelines incorporate the use of new drugs, known as

antiemetics, which patients receive prior to surgery to prevent

nausea and vomiting. The researchers also found that combining

different classes of antiemetics added to their effectiveness.

The guidelines also provide new information that should help

physicians identify which patients are at the greatest risk for

nausea and vomiting and therefore should receive antiemetics prior

to surgery.

" The results of more than 250 trials of antiemetics have been

published since the last guidelines were developed five years ago, "

Gan said. " The new guidelines incorporate much of this new

information and provide physicians with up-to-date strategies for

preventing and treating postoperative nausea and vomiting. "

Children are twice as likely as adults to develop postoperative

nausea and vomiting, Gan said, and the panel developed a simple four-

point scoring system for identifying those children at highest risk.

The four factors are: when a surgical procedure lasts more than 30

minutes; when children are three years of age or older; when there

is a family history of postoperative nausea and vomiting; and when

the surgery is to correct strabismus, or crossed eyes.

" If one of these risk factors is present, then there is a 10 percent

chance of postoperative nausea and vomiting, " Gan said. " Each

additional factor adds another 20 percent chance, meaning that a

child with all four would be at a 70 percent risk. Since the

previous guidelines were developed, there have been a number of

effective antiemetics approved for use in children, and we would

recommend that children identified as being at high risk should be

given a combination of these drugs. "

For adults, the factors that elevate risk include being female,

being a nonsmoker and having a family history of motion sickness or

postoperative nausea and vomiting. Also, long surgeries, or those

that use nitrous oxide as an agent of general anesthesia, increase

risk, Gan said, as does the use of opioids to control pain after

surgery.

The panel concluded that being obese does not increase a patient's

chances of suffering from nausea and vomiting, as was previously

thought, Gan said. Additionally, giving patients 100 percent oxygen

during surgery -- a common preventive strategy -- does not appear to

be effective in controlling nausea and vomiting.

The research team also looked at nontraditional preventive methods.

" We have seen more support among the medical community for the use

of acupuncture before and during surgery to control postoperative

nausea and vomiting, " said Gan, who recently conducted a study which

found that the ancient Chinese practice is effective for managing

the disorder in women undergoing major breast surgery.

[link] " However, we also found that hypnosis before surgery was not

effective as a preventive measure. "

According to Gan, postoperative nausea and vomiting does not receive

enough attention from the medical community.

" There are more than 35 million surgical procedures performed each

year in the United States, so this is an extremely important health

care issue, " Gan said. " It is also an issue that most physicians do

not take seriously enough; they see it as a short-term nuisance that

will soon pass. However, studies have shown that nausea and vomiting

after surgery is the major factor influencing whether or not

patients are satisfied with their surgery. "

The issue is also important for patients who go home in the

afternoon after having surgery in the morning.

" More than 70 percent of all surgeries in the United States are

performed as day cases, and the persistence of nausea and vomiting

symptoms beyond discharge after surgery pose a great challenge to

both patients and their physicians, " Gan said. " So it is important

to consider postoperative nausea and vomiting before surgery and

have an effective strategy to manage it. "

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