Guest guest Posted December 17, 2010 Report Share Posted December 17, 2010 DX is bi-lateral adrenal hyperplasia, hyperaldosteronism. A little over a year ago I started having extremely painful muscle cramps, usually, but not limited to, calf muscles at night. Since then I have had a number of tests, all negative or inclusive. EMG, Ultrasound, MRI, & more. Ruled out circulation, nerve pinch, (I have severe spinal stenosis) etc. I can control the muscle spasms by taking Mg, slow release from Jigsaw, at about double the label dose (yeah, it stimulates the gut, but not so much that I cannot live with that problem). My nephrologist prescribed Eplenerone, but so far the insurance has denied coverage. In preparing to carefully make the switch, We dropped Cozaar, but not Coreg or Spironolactone, which was increased from 75 mg/day to 100 mg/day. My blood pressure is always 115 +/-5 over 75 +/- 5. Sorry, this is a lot of background to get around to the question. Why do I have to take high doses of Mg to prevent crippling, painful muscle cramps? Is it safe to do so over a long period? Mg combines with Ca, am I depleting Ca with large Mg dose? What causes this Mg depletion, if that is what is happening? Thanks for your attention to my question. dk Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 17, 2010 Report Share Posted December 17, 2010 i also experience muscle cramps,my lower extremities the legs of my muscle becomes hard and it is so painful.i experience it early morning,evening and when i swim.i just put liniments and i stretched my extremities even painful, to alleviate the pain.Subject: Mg loss? -To: hyperaldosteronism Date: Friday, 17 December, 2010, 9:26 PM DX is bi-lateral adrenal hyperplasia, hyperaldosteronism. A little over a year ago I started having extremely painful muscle cramps, usually, but not limited to, calf muscles at night. Since then I have had a number of tests, all negative or inclusive. EMG, Ultrasound, MRI, & more. Ruled out circulation, nerve pinch, (I have severe spinal stenosis) etc. I can control the muscle spasms by taking Mg, slow release from Jigsaw, at about double the label dose (yeah, it stimulates the gut, but not so much that I cannot live with that problem). My nephrologist prescribed Eplenerone, but so far the insurance has denied coverage. In preparing to carefully make the switch, We dropped Cozaar, but not Coreg or Spironolactone, which was increased from 75 mg/day to 100 mg/day. My blood pressure is always 115 +/-5 over 75 +/- 5. Sorry, this is a lot of background to get around to the question. Why do I have to take high doses of Mg to prevent crippling, painful muscle cramps? Is it safe to do so over a long period? Mg combines with Ca, am I depleting Ca with large Mg dose? What causes this Mg depletion, if that is what is happening? Thanks for your attention to my question. dk Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 17, 2010 Report Share Posted December 17, 2010 sometimes they say that u don't use your muscle all the time that's why you encounter pain.lack of exercise.massage the painful part of the muscle.some also say apply hot compress on the pain part to alleviate the pain.Some people say cold weather worsened the pain.Subject: Mg loss? -To: hyperaldosteronism Date: Friday, 17 December, 2010, 9:26 PM DX is bi-lateral adrenal hyperplasia, hyperaldosteronism. A little over a year ago I started having extremely painful muscle cramps, usually, but not limited to, calf muscles at night. Since then I have had a number of tests, all negative or inclusive. EMG, Ultrasound, MRI, & more. Ruled out circulation, nerve pinch, (I have severe spinal stenosis) etc. I can control the muscle spasms by taking Mg, slow release from Jigsaw, at about double the label dose (yeah, it stimulates the gut, but not so much that I cannot live with that problem). My nephrologist prescribed Eplenerone, but so far the insurance has denied coverage. In preparing to carefully make the switch, We dropped Cozaar, but not Coreg or Spironolactone, which was increased from 75 mg/day to 100 mg/day. My blood pressure is always 115 +/-5 over 75 +/- 5. Sorry, this is a lot of background to get around to the question. Why do I have to take high doses of Mg to prevent crippling, painful muscle cramps? Is it safe to do so over a long period? Mg combines with Ca, am I depleting Ca with large Mg dose? What causes this Mg depletion, if that is what is happening? Thanks for your attention to my question. dk Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 17, 2010 Report Share Posted December 17, 2010 they say apply DASH.see a nutritionist.Subject: Mg loss? -To: hyperaldosteronism Date: Friday, 17 December, 2010, 9:26 PM DX is bi-lateral adrenal hyperplasia, hyperaldosteronism. A little over a year ago I started having extremely painful muscle cramps, usually, but not limited to, calf muscles at night. Since then I have had a number of tests, all negative or inclusive. EMG, Ultrasound, MRI, & more. Ruled out circulation, nerve pinch, (I have severe spinal stenosis) etc. I can control the muscle spasms by taking Mg, slow release from Jigsaw, at about double the label dose (yeah, it stimulates the gut, but not so much that I cannot live with that problem). My nephrologist prescribed Eplenerone, but so far the insurance has denied coverage. In preparing to carefully make the switch, We dropped Cozaar, but not Coreg or Spironolactone, which was increased from 75 mg/day to 100 mg/day. My blood pressure is always 115 +/-5 over 75 +/- 5. Sorry, this is a lot of background to get around to the question. Why do I have to take high doses of Mg to prevent crippling, painful muscle cramps? Is it safe to do so over a long period? Mg combines with Ca, am I depleting Ca with large Mg dose? What causes this Mg depletion, if that is what is happening? Thanks for your attention to my question. dk Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 17, 2010 Report Share Posted December 17, 2010 Is it true guys that if aldosterone worsened,the blood vessels of my heart and it's muscle of the heart will become thick?this is what my Dr. Solimen told me. Subject: Mg loss? -To: hyperaldosteronism Date: Friday, 17 December, 2010, 9:26 PM DX is bi-lateral adrenal hyperplasia, hyperaldosteronism. A little over a year ago I started having extremely painful muscle cramps, usually, but not limited to, calf muscles at night. Since then I have had a number of tests, all negative or inclusive. EMG, Ultrasound, MRI, & more. Ruled out circulation, nerve pinch, (I have severe spinal stenosis) etc. I can control the muscle spasms by taking Mg, slow release from Jigsaw, at about double the label dose (yeah, it stimulates the gut, but not so much that I cannot live with that problem). My nephrologist prescribed Eplenerone, but so far the insurance has denied coverage. In preparing to carefully make the switch, We dropped Cozaar, but not Coreg or Spironolactone, which was increased from 75 mg/day to 100 mg/day. My blood pressure is always 115 +/-5 over 75 +/- 5. Sorry, this is a lot of background to get around to the question. Why do I have to take high doses of Mg to prevent crippling, painful muscle cramps? Is it safe to do so over a long period? Mg combines with Ca, am I depleting Ca with large Mg dose? What causes this Mg depletion, if that is what is happening? Thanks for your attention to my question. dk Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 17, 2010 Report Share Posted December 17, 2010 No you can DASH and take spiro.Coreg will not do much either. Well will cramp your pocketbook.CE Grim MDDX is bi-lateral adrenal hyperplasia, hyperaldosteronism.A little over a year ago I started having extremely painful muscle cramps, usually, but not limited to, calf muscles at night.Since then I have had a number of tests, all negative or inclusive. EMG, Ultrasound, MRI, & more. Ruled out circulation, nerve pinch, (I have severe spinal stenosis) etc.I can control the muscle spasms by taking Mg, slow release from Jigsaw, at about double the label dose (yeah, it stimulates the gut, but not so much that I cannot live with that problem).My nephrologist prescribed Eplenerone, but so far the insurance has denied coverage. In preparing to carefully make the switch, We dropped Cozaar, but not Coreg or Spironolactone, which was increased from 75 mg/day to 100 mg/day.My blood pressure is always 115 +/-5 over 75 +/- 5.Sorry, this is a lot of background to get around to the question.Why do I have to take high doses of Mg to prevent crippling, painful muscle cramps? Is it safe to do so over a long period? Mg combines with Ca, am I depleting Ca with large Mg dose? What causes this Mg depletion, if that is what is happening?Thanks for your attention to my question.dk Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 17, 2010 Report Share Posted December 17, 2010 YesIs it true guys that if aldosterone worsened,the blood vessels of my heart and it's muscle of the heart will become thick?this is what my Dr. Solimen told me. Subject: Mg loss? -To: hyperaldosteronism Date: Friday, 17 December, 2010, 9:26 PM DX is bi-lateral adrenal hyperplasia, hyperaldosteronism.A little over a year ago I started having extremely painful muscle cramps, usually, but not limited to, calf muscles at night.Since then I have had a number of tests, all negative or inclusive. EMG, Ultrasound, MRI, & more. Ruled out circulation, nerve pinch, (I have severe spinal stenosis) etc.I can control the muscle spasms by taking Mg, slow release from Jigsaw, at about double the label dose (yeah, it stimulates the gut, but not so much that I cannot live with that problem).My nephrologist prescribed Eplenerone, but so far the insurance has denied coverage. In preparing to carefully make the switch, We dropped Cozaar, but not Coreg or Spironolactone, which was increased from 75 mg/day to 100 mg/day.My blood pressure is always 115 +/-5 over 75 +/- 5.Sorry, this is a lot of background to get around to the question.Why do I have to take high doses of Mg to prevent crippling, painful muscle cramps? Is it safe to do so over a long period? Mg combines with Ca, am I depleting Ca with large Mg dose? What causes this Mg depletion, if that is what is happening?Thanks for your attention to my question.dk Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 17, 2010 Report Share Posted December 17, 2010 DASH dammit DASHCE Grim MDi also experience muscle cramps,my lower extremities the legs of my muscle becomes hard and it is so painful.i experience it early morning,evening and when i swim.i just put liniments and i stretched my extremities even painful, to alleviate the pain.Subject: Mg loss? -To: hyperaldosteronism Date: Friday, 17 December, 2010, 9:26 PM DX is bi-lateral adrenal hyperplasia, hyperaldosteronism.A little over a year ago I started having extremely painful muscle cramps, usually, but not limited to, calf muscles at night.Since then I have had a number of tests, all negative or inclusive. EMG, Ultrasound, MRI, & more. Ruled out circulation, nerve pinch, (I have severe spinal stenosis) etc.I can control the muscle spasms by taking Mg, slow release from Jigsaw, at about double the label dose (yeah, it stimulates the gut, but not so much that I cannot live with that problem).My nephrologist prescribed Eplenerone, but so far the insurance has denied coverage. In preparing to carefully make the switch, We dropped Cozaar, but not Coreg or Spironolactone, which was increased from 75 mg/day to 100 mg/day.My blood pressure is always 115 +/-5 over 75 +/- 5.Sorry, this is a lot of background to get around to the question.Why do I have to take high doses of Mg to prevent crippling, painful muscle cramps? Is it safe to do so over a long period? Mg combines with Ca, am I depleting Ca with large Mg dose? What causes this Mg depletion, if that is what is happening?Thanks for your attention to my question.dk Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 17, 2010 Report Share Posted December 17, 2010 I can recommend Mg from Jigsaw Health, (Google it, only available online). It is slow release, so minimum gut stimulation. If I take 4 tablets every 8 hours, I don't have the cramps. It's just I worry about what is ACTUALLY going on. I also work out daily in the pool with a group and trainer. thanks for the reply, dk > > > Subject: Mg loss? - > To: hyperaldosteronism > Date: Friday, 17 December, 2010, 9:26 PM > > > > > > > > Â > > > > > > > > > > DX is bi-lateral adrenal hyperplasia, hyperaldosteronism. > > > > A little over a year ago I started having extremely painful muscle cramps, usually, but not limited to, calf muscles at night. > > > > Since then I have had a number of tests, all negative or inclusive. EMG, Ultrasound, MRI, & more. Ruled out circulation, nerve pinch, (I have severe spinal stenosis) etc. > > > > I can control the muscle spasms by taking Mg, slow release from Jigsaw, at about double the label dose (yeah, it stimulates the gut, but not so much that I cannot live with that problem). > > > > My nephrologist prescribed Eplenerone, but so far the insurance has denied coverage. In preparing to carefully make the switch, We dropped Cozaar, but not Coreg or Spironolactone, which was increased from 75 mg/day to 100 mg/day. > > > > My blood pressure is always 115 +/-5 over 75 +/- 5. > > > > Sorry, this is a lot of background to get around to the question. > > > > Why do I have to take high doses of Mg to prevent crippling, painful muscle cramps? Is it safe to do so over a long period? Mg combines with Ca, am I depleting Ca with large Mg dose? What causes this Mg depletion, if that is what is happening? > > > > Thanks for your attention to my question. > > > > dk > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 17, 2010 Report Share Posted December 17, 2010 I thought that might have been a factor, I had open heart surgery in '08. This started about 3 months later. But since then I have re-developed those muscles with daily hour-long work-out in pool. dk > > > Subject: Mg loss? - > To: hyperaldosteronism > Date: Friday, 17 December, 2010, 9:26 PM > > > > > > > > Â > > > > > > > > > > DX is bi-lateral adrenal hyperplasia, hyperaldosteronism. > > > > A little over a year ago I started having extremely painful muscle cramps, usually, but not limited to, calf muscles at night. > > > > Since then I have had a number of tests, all negative or inclusive. EMG, Ultrasound, MRI, & more. Ruled out circulation, nerve pinch, (I have severe spinal stenosis) etc. > > > > I can control the muscle spasms by taking Mg, slow release from Jigsaw, at about double the label dose (yeah, it stimulates the gut, but not so much that I cannot live with that problem). > > > > My nephrologist prescribed Eplenerone, but so far the insurance has denied coverage. In preparing to carefully make the switch, We dropped Cozaar, but not Coreg or Spironolactone, which was increased from 75 mg/day to 100 mg/day. > > > > My blood pressure is always 115 +/-5 over 75 +/- 5. > > > > Sorry, this is a lot of background to get around to the question. > > > > Why do I have to take high doses of Mg to prevent crippling, painful muscle cramps? Is it safe to do so over a long period? Mg combines with Ca, am I depleting Ca with large Mg dose? What causes this Mg depletion, if that is what is happening? > > > > Thanks for your attention to my question. > > > > dk > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 17, 2010 Report Share Posted December 17, 2010 Dr. Grim, Thanks for your quick reply. I have been DASHing for a couple of months now, based on learning from your posts in this group, with no apparent changes. Still, I wonder about damage from high Mg intake. Any ideas? dk > > > > > > Subject: Mg loss? - > > To: hyperaldosteronism > > Date: Friday, 17 December, 2010, 9:26 PM > > > > > > DX is bi-lateral adrenal hyperplasia, hyperaldosteronism. > > > > A little over a year ago I started having extremely painful muscle > > cramps, usually, but not limited to, calf muscles at night. > > > > Since then I have had a number of tests, all negative or inclusive. > > EMG, Ultrasound, MRI, & more. Ruled out circulation, nerve pinch, (I > > have severe spinal stenosis) etc. > > > > I can control the muscle spasms by taking Mg, slow release from > > Jigsaw, at about double the label dose (yeah, it stimulates the gut, > > but not so much that I cannot live with that problem). > > > > My nephrologist prescribed Eplenerone, but so far the insurance has > > denied coverage. In preparing to carefully make the switch, We > > dropped Cozaar, but not Coreg or Spironolactone, which was increased > > from 75 mg/day to 100 mg/day. > > > > My blood pressure is always 115 +/-5 over 75 +/- 5. > > > > Sorry, this is a lot of background to get around to the question. > > > > Why do I have to take high doses of Mg to prevent crippling, painful > > muscle cramps? Is it safe to do so over a long period? Mg combines > > with Ca, am I depleting Ca with large Mg dose? What causes this Mg > > depletion, if that is what is happening? > > > > Thanks for your attention to my question. > > > > dk > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 17, 2010 Report Share Posted December 17, 2010 Must have been true for me, all studies showed enlarged heart walls for years, then the open heart surgery... dk > > > Subject: Mg loss? - > To: hyperaldosteronism > Date: Friday, 17 December, 2010, 9:26 PM > > > > > > > > Â > > > > > > > > > > DX is bi-lateral adrenal hyperplasia, hyperaldosteronism. > > > > A little over a year ago I started having extremely painful muscle cramps, usually, but not limited to, calf muscles at night. > > > > Since then I have had a number of tests, all negative or inclusive. EMG, Ultrasound, MRI, & more. Ruled out circulation, nerve pinch, (I have severe spinal stenosis) etc. > > > > I can control the muscle spasms by taking Mg, slow release from Jigsaw, at about double the label dose (yeah, it stimulates the gut, but not so much that I cannot live with that problem). > > > > My nephrologist prescribed Eplenerone, but so far the insurance has denied coverage. In preparing to carefully make the switch, We dropped Cozaar, but not Coreg or Spironolactone, which was increased from 75 mg/day to 100 mg/day. > > > > My blood pressure is always 115 +/-5 over 75 +/- 5. > > > > Sorry, this is a lot of background to get around to the question. > > > > Why do I have to take high doses of Mg to prevent crippling, painful muscle cramps? Is it safe to do so over a long period? Mg combines with Ca, am I depleting Ca with large Mg dose? What causes this Mg depletion, if that is what is happening? > > > > Thanks for your attention to my question. > > > > dk > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 17, 2010 Report Share Posted December 17, 2010 Spirinolactone has controlled the HyperAldo for about 25 years. Right now the change to Eplenerone is to resolve the growing painful breasts. (I am glad we are kind of anonymous here) dk > > > DX is bi-lateral adrenal hyperplasia, hyperaldosteronism. > > > > A little over a year ago I started having extremely painful muscle > > cramps, usually, but not limited to, calf muscles at night. > > > > Since then I have had a number of tests, all negative or inclusive. > > EMG, Ultrasound, MRI, & more. Ruled out circulation, nerve pinch, (I > > have severe spinal stenosis) etc. > > > > I can control the muscle spasms by taking Mg, slow release from > > Jigsaw, at about double the label dose (yeah, it stimulates the gut, > > but not so much that I cannot live with that problem). > > > > My nephrologist prescribed Eplenerone, but so far the insurance has > > denied coverage. In preparing to carefully make the switch, We > > dropped Cozaar, but not Coreg or Spironolactone, which was increased > > from 75 mg/day to 100 mg/day. > > > > My blood pressure is always 115 +/-5 over 75 +/- 5. > > > > Sorry, this is a lot of background to get around to the question. > > > > Why do I have to take high doses of Mg to prevent crippling, painful > > muscle cramps? Is it safe to do so over a long period? Mg combines > > with Ca, am I depleting Ca with large Mg dose? What causes this Mg > > depletion, if that is what is happening? > > > > Thanks for your attention to my question. > > > > dk > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 17, 2010 Report Share Posted December 17, 2010 GranPaSmurf, I'm not a doctor or even a medical person, but I have some amateur perspective on a few of your questions You asked why you're losing magnesium -- that's another effect of aldosterone. Even though I have none of the other markers for low magnesium (e.g. alcoholism), when I was admitted to the hospital with dangerously low potassium and a cerebral hemorrhage, I also had extremely low magnesium. If you Google aldosterone magnesium, you'll immediately see a bunch of articles on a direct connection between the two. Low magnesium also impairs one's ability to hold onto potassium. In fact, magnesium has been shown to reduce aldosterone secretion in rat adrenal tissue. I don't recall whether that was healthy rat adrenal tissue or aldosteronistic rat adrenal tissue. But regardless of that, some doctors have always said that throwing potassium pills at hypokalemia without adding magnesium was an exercise in flushing potassium down the drain. Generally speaking, taking magnesium is GOOD for your calcium metabolism, not a threat to it. Some researchers believe the reason America has so much osteoporosis has nothing to do with low calcium intake. The US has high calcium intake -- far too much, some researchers say -- compared to much of the world with stronger bones than us. Our problem with bone hardness is low magnesium intake, which also contributes to our type 2 diabetes and " metabolic syndrome, " a form of pre-diabetes that includes hypertension, insulin resistance, and unhealthy blood-fat profiles. Magnesium is the overlooked bone-hardener and getting enough of it is crucial to the proper housekeeping of calcium. Groups in the U.S. that live in our few areas with magnesium-rich, calcium-poor tap water have significantly lower prevalence of many of our common health problems like heart attack, stroke, osteoporosis, and others. And when Finland, with naturally magnesium-poor tap water, got its entire food industry to replace regular table salt with sodium-poorer, magnesium-rich salt, they managed to transform the country from heart-attack capital into a public health success story. However, those results have eroded as more processed food from the rest of the EU, with its ordinary table salt, have increasingly come to dominate the Finnish table. The exception to magnesium's benefits begin when you take enough to be getting diarrhea. At that point, it is sucking minerals out of your body through the gut. There are topical products misleadingly called " magnesium oil " that you can use to absorb magnesium directly through the skin. They are actually just water-based gels supersaturated with magnesium salts. I wonder how those would affect your cramping muscles. And of course you can dump a whole bag of Epsom salt into the bathtub and sit for a soak. My wife and I often do that. Or maybe for absorption purposes, it would be better (more concentrated) just to soak your feet in warm water in a plastic dish-washing basin with as much Epsom salt (magnesium sulfate) as you can get to dissolve in it. Since magnesium is such an important part of your life, you might be interested in the book " The Magnesium Factor, " by Mildred Selig, M.D. and a nutritionist co-author. It is a summary for us laypeople of much of the best mainstream medical research about magnesium. I have discovered that caffeine is worse for me than it is for most people. It further depletes the minerals I have trouble holding on to. Although I love it and nowadays drink only about one soda-can's worth a day, I have learned there is also a possibility it is affecting my adrenal hormones to increase aldosterone while suppressing some other ones. (I'm not saying that is the effect in most people.) For years when young, I drank easily ten times that daily amount of caffeine, or more, and may have brought about some adrenal adaptation. Swimming is a good thing on balance, of course. But swimming in treated pools always made me extremely thirsty in my youth. I learned later that swimming is another of those things that can suck both water and minerals out of your body through the skin while increasing your internal Cl levels. That might be having some effect on your cramps, I don't know. Forewarned is forearmed, and maybe you could devise some measures based on what times of day you swim to counteract such effects. Alden Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 17, 2010 Report Share Posted December 17, 2010 Or you can DASH-a high Mg eating plan. Healthier and cheaper I suspect.CE GrimI can recommend Mg from Jigsaw Health, (Google it, only available online). It is slow release, so minimum gut stimulation. If I take 4 tablets every 8 hours, I don't have the cramps. It's just I worry about what is ACTUALLY going on. I also work out daily in the pool with a group and trainer.thanks for the reply,dk> > > Subject: Mg loss? -> To: hyperaldosteronism > Date: Friday, 17 December, 2010, 9:26 PM> > > > > > > > Â > > > > > > > > > > DX is bi-lateral adrenal hyperplasia, hyperaldosteronism.> > > > A little over a year ago I started having extremely painful muscle cramps, usually, but not limited to, calf muscles at night.> > > > Since then I have had a number of tests, all negative or inclusive. EMG, Ultrasound, MRI, & more. Ruled out circulation, nerve pinch, (I have severe spinal stenosis) etc.> > > > I can control the muscle spasms by taking Mg, slow release from Jigsaw, at about double the label dose (yeah, it stimulates the gut, but not so much that I cannot live with that problem).> > > > My nephrologist prescribed Eplenerone, but so far the insurance has denied coverage. In preparing to carefully make the switch, We dropped Cozaar, but not Coreg or Spironolactone, which was increased from 75 mg/day to 100 mg/day.> > > > My blood pressure is always 115 +/-5 over 75 +/- 5.> > > > Sorry, this is a lot of background to get around to the question.> > > > Why do I have to take high doses of Mg to prevent crippling, painful muscle cramps? Is it safe to do so over a long period? Mg combines with Ca, am I depleting Ca with large Mg dose? What causes this Mg depletion, if that is what is happening?> > > > Thanks for your attention to my question.> > > > dk> Quote Link to comment Share on other sites More sharing options...
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