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We almost Never give both an ACE and and ARB in US. Which diuretic are you on?Then it's strange, since both this groups seem working for me. My renin plasma activity is 0.36.To: hyperaldosteronism Sent: Sat, February 5, 2011 8:33:33 PMSubject: RE: Re: 39 yr old WM with HTN slightly low K and no adrenal mass OOPS! sorry, Dr Grim said rennin, I confused rennin with cortisol: about ACE & A2RB not working. Max.61M L adenoma NP59 Spiro=100, Amlo=10, Indap=2.5, Ramip=5, Metf=1000, Prav=40, Feno=67, K.cl=120 mEq>Dr. Grim explained that using ACE or A2RB you try to block cortisol that PA patient already does not have and hence aldo/cortisol ratio goes up causing bp goes up. I didn't read that and it's a point! My aldo is low and my cortisol is high. So, we are different!

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