RE: Re: PA, insulin resistance/metabolic syndrome, and weight gain

[Guest guest]

Very rare. Aldo may stimulate salt appetite and when you eat more salt you tend to drink more sweet things and thus more sWeight. Tiped sad Send form miiPhone ;-)May your pressure be low!CE Grim MDSpecializing in DifficultHypertension

Thanks Dr. Grim! A Dr. Conn reader is a great idea

Can an adrenal tumor cause both high aldo *and* high cortisol? I haven't had my cortisol measured but am starting to think it might be a good idea.

>

> > I see a lot of posts here in which weight gain is an issue for people, and thought this was worth discussing.

> >

> > I've found a lot of medical studies proposing a link between PA and insulin resistance/metabolic syndrome. For me, the first time that something was amiss was probably sudden weight *gain* - after a lifetime of being underweight, I gained 50 pounds in one year and was diagnosed with insulin resistance, long before I ever was diagnosed with HTN or PA. (Check the Files section for "msmith1928's story" for more.)

> >

> > Via dietary changes I lost the weight really quickly and have kept it off for almost 10 years now. However, I remain really susceptible to weight gain, mostly from medications.

> >

> > I'm wondering if others with PA have had issues with weight that came on suddenly. I've seen references to the adrenals controlling sugar metabolism, such as this: http://www.umm.edu/general_surgery/lap_adrenalectomy.htm, and I'm wondering if it can be said that adrenal tumors can contribute to or cause insulin resistance?

> >

> > - msmith1928

> > 45, female, 5'3", 120 lbs, 1cm left adrenal nodule, aldosterone 42.3, renin 0.5, potassium <2.9 (when not taking supplements)

> >

> >

>

[Guest guest]

I

believe there are many studies linking IR and PA. Dr. Grim has talked about it as well. Do a PubMed and see what you find.

Val

From: hyperaldosteronism

[mailto:hyperaldosteronism ] On Behalf Of msmith_1928

>

> I see a lot of posts here in which weight gain is an issue for people, and

thought this was worth discussing.

>

> I've found a lot of medical studies proposing a link between PA and

insulin resistance/metabolic syndrome. For me, the first time that something

was amiss was probably sudden weight *gain* - after a lifetime of being

underweight, I gained 50 pounds in one year and was diagnosed with insulin

resistance, long before I ever was diagnosed with HTN or PA. (Check the Files

section for " msmith1928's story " for more.)

>

> Via dietary changes I lost the weight really quickly and have kept it off

for almost 10 years now. However, I remain really susceptible to weight gain,

mostly from medications.

>

> I'm wondering if others with PA have had issues with weight that came on

suddenly. I've seen references to the adrenals controlling sugar metabolism,

such as this: http://www.umm.edu/general_surgery/lap_adrenalectomy.htm,

and I'm wondering if it can be said that adrenal tumors can contribute to or

cause insulin resistance?

>

> - msmith1928

> 45, female, 5'3 " , 120 lbs, 1cm left adrenal nodule, aldosterone 42.3,

renin 0.5, potassium <2.9 (when not taking supplements)

>

[Guest guest]

I

believe there are many studies linking IR and PA. Dr. Grim has talked about it as well. Do a PubMed and see what you find.

Val

From: hyperaldosteronism

[mailto:hyperaldosteronism ] On Behalf Of msmith_1928

>

> I see a lot of posts here in which weight gain is an issue for people, and

thought this was worth discussing.

>

> I've found a lot of medical studies proposing a link between PA and

insulin resistance/metabolic syndrome. For me, the first time that something

was amiss was probably sudden weight *gain* - after a lifetime of being

underweight, I gained 50 pounds in one year and was diagnosed with insulin

resistance, long before I ever was diagnosed with HTN or PA. (Check the Files

section for " msmith1928's story " for more.)

>

> Via dietary changes I lost the weight really quickly and have kept it off

for almost 10 years now. However, I remain really susceptible to weight gain,

mostly from medications.

>

> I'm wondering if others with PA have had issues with weight that came on

suddenly. I've seen references to the adrenals controlling sugar metabolism,

such as this: http://www.umm.edu/general_surgery/lap_adrenalectomy.htm,

and I'm wondering if it can be said that adrenal tumors can contribute to or

cause insulin resistance?

>

> - msmith1928

> 45, female, 5'3 " , 120 lbs, 1cm left adrenal nodule, aldosterone 42.3,

renin 0.5, potassium <2.9 (when not taking supplements)

>

[Guest guest]

Taking

spiro did nothing for my resistant weight.

Getting Lyme treatment did.

I've lost 29 pounds since last June. For me, that's remarkable. Spiro and Inspra, BTW, did nothing in

terms of helping me feel better, cutting the " brittles, " etc.

F, Lyme

disease 24.5 years before diagnosis, hypothyroid, hyperparathyroid, PA, BC, on

Inspra 75 mg, several antibiotics.

Val

From: hyperaldosteronism

[mailto:hyperaldosteronism ] On Behalf Of msmith_1928

Thanks Val, I've already done that, but would really be

interested in hearing the real-life experiences of others on this forum.

I've heard a few stories about weight *gain* after diagnosis, either after

starting meds or after adrenalectomy, and that is the last thing I am hoping

for! I'm hopeful that treating the PA will help treat the IR, but I haven't

seen much evidence of this.

- msmith1928

45, female, 5'3 " , 120 lbs, 1cm left adrenal nodule, aldosterone 42.3,

renin 0.5, potassium <2.9 (when not taking supplements); 25mg spiro caused

gynecomastia

[Guest guest]

The IR goes away if it is due to aldo and low K and they go away.Same for spiro I recall.Still if you eat too much and don't have enough exercise and the wrong genes you get IR then type 2 DM and maybe even need insulin.CE Grim MDThanks Val, I've already done that, but would really be interested in hearing the real-life experiences of others on this forum.I've heard a few stories about weight *gain* after diagnosis, either after starting meds or after adrenalectomy, and that is the last thing I am hoping for! I'm hopeful that treating the PA will help treat the IR, but I haven't seen much evidence of this.- msmith192845, female, 5'3", 120 lbs, 1cm left adrenal nodule, aldosterone 42.3, renin 0.5, potassium <2.9 (when not taking supplements); 25mg spiro caused gynecomastia> >> > I see a lot of posts here in which weight gain is an issue for people, and> thought this was worth discussing.> > > > I've found a lot of medical studies proposing a link between PA and> insulin resistance/metabolic syndrome. For me, the first time that something> was amiss was probably sudden weight *gain* - after a lifetime of being> underweight, I gained 50 pounds in one year and was diagnosed with insulin> resistance, long before I ever was diagnosed with HTN or PA. (Check the> Files section for "msmith1928's story" for more.)> > > > Via dietary changes I lost the weight really quickly and have kept it off> for almost 10 years now. However, I remain really susceptible to weight> gain, mostly from medications.> > > > I'm wondering if others with PA have had issues with weight that came on> suddenly. I've seen references to the adrenals controlling sugar metabolism,> such as this: http://www.umm.edu/general_surgery/lap_adrenalectomy.htm, and> I'm wondering if it can be said that adrenal tumors can contribute to or> cause insulin resistance?> > > > - msmith1928> > 45, female, 5'3", 120 lbs, 1cm left adrenal nodule, aldosterone 42.3,> renin 0.5, potassium <2.9 (when not taking supplements)> >>

[Guest guest]

It is called the Evolution of Primary Aldosteronism in our files.Dr. Grim, could you clarify what you mean by "your review"? Is it something I can find in the Files section here, or do I need to track it down on PubMed? Thanks.> > >> > > I see a lot of posts here in which weight gain is an issue for > > people, and thought this was worth discussing.> > >> > > I've found a lot of medical studies proposing a link between PA > > and insulin resistance/metabolic syndrome. For me, the first time > > that something was amiss was probably sudden weight *gain* - after a > > lifetime of being underweight, I gained 50 pounds in one year and > > was diagnosed with insulin resistance, long before I ever was > > diagnosed with HTN or PA. (Check the Files section for "msmith1928's > > story" for more.)> > >> > > Via dietary changes I lost the weight really quickly and have kept > > it off for almost 10 years now. However, I remain really susceptible > > to weight gain, mostly from medications.> > >> > > I'm wondering if others with PA have had issues with weight that > > came on suddenly. I've seen references to the adrenals controlling > > sugar metabolism, such as this:http://www.umm.edu/general_surgery/lap_adrenalectomy.htm > > , and I'm wondering if it can be said that adrenal tumors can > > contribute to or cause insulin resistance?> > >> > > - msmith1928> > > 45, female, 5'3", 120 lbs, 1cm left adrenal nodule, aldosterone > > 42.3, renin 0.5, potassium <2.9 (when not taking supplements)> > >> >> >> >> >>

[Guest guest]

What are you taking for your lymes? I'm having trouble finding a dr that believes lymes doesn't just go away after one treatment. Thanks ValJaNelle

Taking

spiro did nothing for my resistant weight.

Getting Lyme treatment did.

I've lost 29 pounds since last June. For me, that's remarkable. Spiro and Inspra, BTW, did nothing in

terms of helping me feel better, cutting the "brittles," etc.

F, Lyme

disease 24.5 years before diagnosis, hypothyroid, hyperparathyroid, PA, BC, on

Inspra 75 mg, several antibiotics.

Val

From: hyperaldosteronism

[mailto:hyperaldosteronism ] On Behalf Of msmith_1928

Thanks Val, I've already done that, but would really be

interested in hearing the real-life experiences of others on this forum.

I've heard a few stories about weight *gain* after diagnosis, either after

starting meds or after adrenalectomy, and that is the last thing I am hoping

for! I'm hopeful that treating the PA will help treat the IR, but I haven't

seen much evidence of this.

- msmith1928

45, female, 5'3", 120 lbs, 1cm left adrenal nodule, aldosterone 42.3,

renin 0.5, potassium <2.9 (when not taking supplements); 25mg spiro caused

gynecomastia

[Guest guest]

When I was on the three month course of antibiotics, for lymes, I lost weight so easily.

Taking

spiro did nothing for my resistant weight.

Getting Lyme treatment did.

I've lost 29 pounds since last June. For me, that's remarkable. Spiro and Inspra, BTW, did nothing in

terms of helping me feel better, cutting the "brittles," etc.

F, Lyme

disease 24.5 years before diagnosis, hypothyroid, hyperparathyroid, PA, BC, on

Inspra 75 mg, several antibiotics.

Val

From: hyperaldosteronism

[mailto:hyperaldosteronism ] On Behalf Of msmith_1928

Thanks Val, I've already done that, but would really be

interested in hearing the real-life experiences of others on this forum.

I've heard a few stories about weight *gain* after diagnosis, either after

starting meds or after adrenalectomy, and that is the last thing I am hoping

for! I'm hopeful that treating the PA will help treat the IR, but I haven't

seen much evidence of this.

- msmith1928

45, female, 5'3", 120 lbs, 1cm left adrenal nodule, aldosterone 42.3,

renin 0.5, potassium <2.9 (when not taking supplements); 25mg spiro caused

gynecomastia

[Guest guest]

Hmm wonder if it they killed bugs that normally break down fat in GI tract.Maybe your team has a new wt loss treatment.CE Grim MDWhen I was on the three month course of antibiotics, for lymes, I lost weight so easily. Taking spiro did nothing for my resistant weight. Getting Lyme treatment did. I've lost 29 pounds since last June. For me, that's remarkable. Spiro and Inspra, BTW, did nothing in terms of helping me feel better, cutting the "brittles," etc. F, Lyme disease 24.5 years before diagnosis, hypothyroid, hyperparathyroid, PA, BC, on Inspra 75 mg, several antibiotics. Val From: hyperaldosteronism [mailto:hyperaldosteronism ] On Behalf Of msmith_1928Thanks Val, I've already done that, but would really be interested in hearing the real-life experiences of others on this forum.I've heard a few stories about weight *gain* after diagnosis, either after starting meds or after adrenalectomy, and that is the last thing I am hoping for! I'm hopeful that treating the PA will help treat the IR, but I haven't seen much evidence of this.- msmith192845, female, 5'3", 120 lbs, 1cm left adrenal nodule, aldosterone 42.3, renin 0.5, potassium <2.9 (when not taking supplements); 25mg spiro caused gynecomastia

[Guest guest]

Assuming one was at least doxycycline it is known for stomach issues and

decreasing appetite. it could be as simple as that.

>When I was on the three month course of antibiotics, for lymes, I lost weight

so easily.

>

>

>

>

>

>> Taking spiro did nothing for my resistant weight. Getting Lyme treatment

did. I've lost 29 pounds since last June. For me, that's remarkable. Spiro

and Inspra, BTW, did nothing in terms of helping me feel better, cutting the

" brittles, " etc.

>>

>>

>>

>> F, Lyme disease 24.5 years before diagnosis, hypothyroid, hyperparathyroid,

PA, BC, on Inspra 75 mg, several antibiotics.

>>

>>

>>

>> Val

>>

>>

>>

>> From: hyperaldosteronism

[mailto:hyperaldosteronism ] On Behalf Of msmith_1928

>>

>>

>> Thanks Val, I've already done that, but would really be interested in hearing

the real-life experiences of others on this forum.

>>

>> I've heard a few stories about weight *gain* after diagnosis, either after

starting meds or after adrenalectomy, and that is the last thing I am hoping

for! I'm hopeful that treating the PA will help treat the IR, but I haven't seen

much evidence of this.

>>

>> - msmith1928

>> 45, female, 5'3 " , 120 lbs, 1cm left adrenal nodule, aldosterone 42.3, renin

0.5, potassium <2.9 (when not taking supplements); 25mg spiro caused

gynecomastia

>>

>>

>>

>>

[Guest guest]

I'll bring that up. I found a new primary care and see him 9 march. I saw him when he was on call and he was brilliant. I left a message with Dr Jim Poole. The endo in Houston that you recommended. Here's hoping they call back! thanks forthe info. My plan is to ask Dr Ninan (gp) to do labsRenin, Aldo , K and thyroid? Then I would have current labs for Dr Poole. I need to get on a proper computer and write up a tagline and history for this group. I had adrenalectomy about 5 years ago and am now experiencing symptoms again. The AVS wasn't able to get a good reading on the right. The adrenal I still have. My BP was so bad during AVS that they had to give up. I don't have any current labs because the endo I saw said- I'm not sure you even had an adrenalectomy since they don't do it laproscopic. Also if I had it then all symptoms go away after surgery so I must just have high BP. I won't be going back there. I blew off symptoms because I had so many other health issues like breast cancer. So I thought the BP, sudden change in cholesterol, fatigue, confusion, irritability etc etc were just due to the can ER and RAI've had 9 surgeries in about 7 years so I'm looking for a trade in.

Hmm wonder if it they killed bugs that normally break down fat in GI tract.Maybe your team has a new wt loss treatment.CE Grim MDWhen I was on the three month course of antibiotics, for lymes, I lost weight so easily. Taking spiro did nothing for my resistant weight. Getting Lyme treatment did. I've lost 29 pounds since last June. For me, that's remarkable. Spiro and Inspra, BTW, did nothing in terms of helping me feel better, cutting the "brittles," etc. F, Lyme disease 24.5 years before diagnosis, hypothyroid, hyperparathyroid, PA, BC, on Inspra 75 mg, several antibiotics. Val From: hyperaldosteronism [mailto:hyperaldosteronism ] On Behalf Of msmith_1928Thanks Val, I've already done that, but would really be interested in hearing the real-life experiences of others on this forum.I've heard a few stories about weight *gain* after diagnosis, either after starting meds or after adrenalectomy, and that is the last thing I am hoping for! I'm hopeful that treating the PA will help treat the IR, but I haven't seen much evidence of this.- msmith192845, female, 5'3", 120 lbs, 1cm left adrenal nodule, aldosterone 42.3, renin 0.5, potassium <2.9 (when not taking supplements); 25mg spiro caused gynecomastia

[Guest guest]

I have adrenal tumor, very low renin, low aldo and high cortisol and I am also diabetic.So, I am an example. When I started eplerenone and dropped many other BP medications, my sugar is much better now (changed from 150 in the morning to 120 in average). I also dropped two diabetes medications. But I am not sure whether it's DASH, droppind bad for me medications or eplerenone, what caused this effect.

Natalia Kamneva 66 Russian F

with 1.5 cm adrenal adenoma, HTN and low renin , low aldosteron and high

cortisol, K=3.4; diabetic.

To: hyperaldosteronism Sent: Sun, February 27, 2011 11:28:28 AMSubject: Re: PA, insulin resistance/metabolic syndrome, and weight gain

Thanks Dr. Grim! A Dr. Conn reader is a great idea

Can an adrenal tumor cause both high aldo *and* high cortisol? I haven't had my cortisol measured but am starting to think it might be a good idea.

>

> > I see a lot of posts here in which weight gain is an issue for people, and thought this was worth discussing.

> >

> > I've found a lot of medical studies proposing a link between PA and insulin resistance/metabolic syndrome. For me, the first time that something was amiss was probably sudden weight *gain* - after a lifetime of being underweight, I gained 50 pounds in one year and was diagnosed with insulin resistance, long before I ever was diagnosed with HTN or PA. (Check the Files section for "msmith1928's story" for more.)

> >

> > Via dietary changes I lost the weight really quickly and have kept it off for almost 10 years now. However, I remain really susceptible to weight gain, mostly from medications.

> >

> > I'm wondering if others with PA have had issues with weight that came on suddenly. I've seen references to the adrenals controlling sugar metabolism, such as this: http://www.umm.edu/general_surgery/lap_adrenalectomy.htm, and I'm wondering if it can be said that adrenal tumors can contribute to or cause insulin resistance?

> >

> > - msmith1928

> > 45, female, 5'3", 120 lbs, 1cm left adrenal nodule, aldosterone 42.3, renin 0.5, potassium <2.9 (when not taking supplements)

> >

> >

>

[Guest guest]

You have an adrenal bump (we dont know if it is fat or muscle or what) and are likely eating a lot of salt that suppresses renin and aldo or have AME or Liddle's syndrome.The spiro response suggests one of the last 2 as would not work just with excess salt.We need to get you to a good Dr. who can help.CE Grim MDI have adrenal tumor, very low renin, low aldo and high cortisol and I am also diabetic.So, I am an example. When I started eplerenone and dropped many other BP medications, my sugar is much better now (changed from 150 in the morning to 120 in average). I also dropped two diabetes medications. But I am not sure whether it's DASH, droppind bad for me medications or eplerenone, what caused this effect. Natalia Kamneva 66 Russian F with 1.5 cm adrenal adenoma, HTN and low renin , low aldosteron and high cortisol, K=3.4; diabetic.To: hyperaldosteronism Sent: Sun, February 27, 2011 11:28:28 AMSubject: Re: PA, insulin resistance/metabolic syndrome, and weight gain Thanks Dr. Grim! A Dr. Conn reader is a great idea :)Can an adrenal tumor cause both high aldo *and* high cortisol? I haven't had my cortisol measured but am starting to think it might be a good idea.> > > I see a lot of posts here in which weight gain is an issue for people, and thought this was worth discussing.> > > > I've found a lot of medical studies proposing a link between PA and insulin resistance/metabolic syndrome. For me, the first time that something was amiss was probably sudden weight *gain* - after a lifetime of being underweight, I gained 50 pounds in one year and was diagnosed with insulin resistance, long before I ever was diagnosed with HTN or PA. (Check the Files section for "msmith1928's story" for more.)> > > > Via dietary changes I lost the weight really quickly and have kept it off for almost 10 years now. However, I remain really susceptible to weight gain, mostly from medications.> > > > I'm wondering if others with PA have had issues with weight that came on suddenly. I've seen references to the adrenals controlling sugar metabolism, such as this:http://www.umm.edu/general_surgery/lap_adrenalectomy.htm, and I'm wondering if it can be said that adrenal tumors can contribute to or cause insulin resistance?> > > > - msmith1928> > 45, female, 5'3", 120 lbs, 1cm left adrenal nodule, aldosterone 42.3, renin 0.5, potassium <2.9 (when not taking supplements)> > > >>

[Guest guest]

Right

now, I'm on IV Rocephin, Septra DS and IV Zithromycin and some supplements.  I was doing really well and except for

fractured sleep, was feeling normal on most days   from

November - mid January.  In January, I underwent

a nine-hour breast cancer surgery.  It

destroyed my innards and bladder (a relapse of symptoms).  That's when the IV Zith was added.  It stopped the stomach pain in two days.  I won't be on that too long and hopefully,

will recover quickly.  I have another

surgery in April.

BTW,

your doctor is horribly misinformed; misinformed enough to kill you. 

Val

From: hyperaldosteronism

[mailto:hyperaldosteronism ] On Behalf Of Txsgreen

What

are you taking for your lymes? I'm having trouble finding a dr that believes

lymes doesn't just go away after one treatment. Thanks Val

JaNelle

Taking spiro did nothing for my resistant

weight. Getting Lyme treatment did. I've lost 29 pounds since last

June. For me, that's remarkable. Spiro and Inspra, BTW, did nothing

in terms of helping me feel better, cutting the " brittles, " etc.

F, Lyme disease 24.5 years before diagnosis,

hypothyroid, hyperparathyroid, PA, BC, on Inspra 75 mg, several antibiotics.

From: hyperaldosteronism

[mailto:hyperaldosteronism ] On Behalf Of msmith_1928

Thanks Val, I've already done that, but would really be interested in

hearing the real-life experiences of others on this forum.

I've heard a few stories about weight *gain* after diagnosis, either after

starting meds or after adrenalectomy, and that is the last thing I am hoping

for! I'm hopeful that treating the PA will help treat the IR, but I haven't

seen much evidence of this.

- msmith1928

45, female, 5'3 " , 120 lbs, 1cm left adrenal nodule, aldosterone 42.3,

renin 0.5, potassium <2.9 (when not taking supplements); 25mg spiro caused

gynecomastia

[Guest guest]

I was

on doxycycline at first for about five weeks. 

I gained another ten pounds.  Go

figure.  I'm surprised you got

three-months.  How long from infection to

treatment?  The longer the time period,

the more difficult it is to treat Lyme. 

I eventually expect to get off Inspra.

Val

From: hyperaldosteronism

[mailto:hyperaldosteronism ] On Behalf Of Txsgreen

When I was on the three month course of antibiotics, for

lymes, I lost weight so easily.

[Guest guest]

I

gained 10 pounds in five weeks on doxy.

Val

From: hyperaldosteronism

[mailto:hyperaldosteronism ] On Behalf Of Bingham

Assuming one was at least doxycycline it is known for

stomach issues and decreasing appetite. it could be as simple as that.

>When I was on the three month course of antibiotics, for lymes, I lost

weight so easily.

[Guest guest]

So it wasn't one of the antibiotics or it was? Was that one they used first? Which ones did you LOSE weight on? Maybe you're on to something good....or just healthy now that they got to the issue

>When I was on the three month course of antibiotics, for lymes, I lost

weight so easily.

[Guest guest]

My

weight loss, the first ever since I got sick, began when I went on IV

Rocephin.  Say what you want about

eataholic disease, it is reasonable that metabolism can be affected, probably by

multitudes of factors, most unknown. 

Val

From: hyperaldosteronism

[mailto:hyperaldosteronism ] On Behalf Of Bingham

So

it wasn't one of the antibiotics or it was? Was that one they used first?

Which ones did you LOSE weight on? Maybe you're on to something good....or

just healthy now that they got to the issue

>When I was on the three month course of antibiotics, for lymes, I lost

weight so easily.

[Guest guest]

Completely agree again. And since I don't eat a lot of salt, then, probably, AME or Liddle's.

I am trying to read about about both diseases and I am trying to find a good doctor, who will believe me and then you.

Many thanks.

Natalia

To: hyperaldosteronism Cc: Clarence Grim Sent: Mon, February 28, 2011 11:14:20 PMSubject: Re: Re: PA, insulin resistance/metabolic syndrome, and weight gain

You have an adrenal bump (we dont know if it is fat or muscle or what) and are likely eating a lot of salt that suppresses renin and aldo or have AME or Liddle's syndrome.

The spiro response suggests one of the last 2 as would not work just with excess salt.

We need to get you to a good Dr. who can help.

CE Grim MD

I have adrenal tumor, very low renin, low aldo and high cortisol and I am also diabetic.So, I am an example. When I started eplerenone and dropped many other BP medications, my sugar is much better now (changed from 150 in the morning to 120 in average). I also dropped two diabetes medications. But I am not sure whether it's DASH, droppind bad for me medications or eplerenone, what caused this effect.

Natalia Kamneva 66 Russian F with 1.5 cm adrenal adenoma, HTN and low renin , low aldosteron and high cortisol, K=3.4; diabetic.

To: hyperaldosteronism Sent: Sun, February 27, 2011 11:28:28 AMSubject: Re: PA, insulin resistance/metabolic syndrome, and weight gain

Thanks Dr. Grim! A Dr. Conn reader is a great idea :)Can an adrenal tumor cause both high aldo *and* high cortisol? I haven't had my cortisol measured but am starting to think it might be a good idea.> > > I see a lot of posts here in which weight gain is an issue for people, and thought this was worth discussing.> > > > I've found a lot of medical studies proposing a link between PA and insulin resistance/metabolic syndrome. For me, the first time that something was amiss was probably sudden weight *gain*

- after a lifetime of being underweight, I gained 50 pounds in one year and was diagnosed with insulin resistance, long before I ever was diagnosed with HTN or PA. (Check the Files section for "msmith1928's story" for more.)> > > > Via dietary changes I lost the weight really quickly and have kept it off for almost 10 years now. However, I remain really susceptible to weight gain, mostly from medications.> > > > I'm wondering if others with PA have had issues with weight that came on suddenly. I've seen references to the adrenals controlling sugar metabolism, such as this:http://www.umm.edu/general_surgery/lap_adrenalectomy.htm, and I'm wondering if it can be said that adrenal tumors can contribute to or cause insulin resistance?> > > > - msmith1928> > 45, female, 5'3", 120 lbs, 1cm left adrenal nodule, aldosterone 42.3, renin 0.5, potassium <2.9 (when not taking supplements)> > > >>

[Guest guest]

That is what I do. I can train you and your current team to do this right without going to a bunch of folks you don't know and who likely don't know about AME or Liddle's.Hire me and save time and $. CE Grim MDCompletely agree again. And since I don't eat a lot of salt, then, probably, AME or Liddle's.I am trying to read about about both diseases and I am trying to find a good doctor, who will believe me and then you. Many thanks. NataliaTo: hyperaldosteronism Cc: Clarence Grim Sent: Mon, February 28, 2011 11:14:20 PMSubject: Re: Re: PA, insulin resistance/metabolic syndrome, and weight gain You have an adrenal bump (we dont know if it is fat or muscle or what) and are likely eating a lot of salt that suppresses renin and aldo or have AME or Liddle's syndrome.The spiro response suggests one of the last 2 as would not work just with excess salt.We need to get you to a good Dr. who can help.CE Grim MDI have adrenal tumor, very low renin, low aldo and high cortisol and I am also diabetic.So, I am an example. When I started eplerenone and dropped many other BP medications, my sugar is much better now (changed from 150 in the morning to 120 in average). I also dropped two diabetes medications. But I am not sure whether it's DASH, droppind bad for me medications or eplerenone, what caused this effect. Natalia Kamneva 66 Russian F with 1.5 cm adrenal adenoma, HTN and low renin , low aldosteron and high cortisol, K=3.4; diabetic.To: hyperaldosteronism Sent: Sun, February 27, 2011 11:28:28 AMSubject: Re: PA, insulin resistance/metabolic syndrome, and weight gain Thanks Dr. Grim! A Dr. Conn reader is a great idea :)Can an adrenal tumor cause both high aldo *and* high cortisol? I haven't had my cortisol measured but am starting to think it might be a good idea.> > > I see a lot of posts here in which weight gain is an issue for people, and thought this was worth discussing.> > > > I've found a lot of medical studies proposing a link between PA and insulin resistance/metabolic syndrome. For me, the first time that something was amiss was probably sudden weight *gain* - after a lifetime of being underweight, I gained 50 pounds in one year and was diagnosed with insulin resistance, long before I ever was diagnosed with HTN or PA. (Check the Files section for "msmith1928's story" for more.)> > > > Via dietary changes I lost the weight really quickly and have kept it off for almost 10 years now. However, I remain really susceptible to weight gain, mostly from medications.> > > > I'm wondering if others with PA have had issues with weight that came on suddenly. I've seen references to the adrenals controlling sugar metabolism, such as this:http://www.umm.edu/general_surgery/lap_adrenalectomy.htm, and I'm wondering if it can be said that adrenal tumors can contribute to or cause insulin resistance?> > > > - msmith1928> > 45, female, 5'3", 120 lbs, 1cm left adrenal nodule, aldosterone 42.3, renin 0.5, potassium <2.9 (when not taking supplements)> > > >>

[Guest guest]

Thank you for the info. I'll keep trying to get treated. I'm in Texas now so they are even less informed since it's not a 'local' illness. I find that when a dr doesn't know something they would rather belittle you than educate themselves. Well obviously not all Drs but too many of them. I've had Drs that encouraged me to learn as much about my illness as possible then you have the ones who won't even let you have a copy of your own labsBest of luck to you ,Val. That is one horrific surgery. Are you cancer free now? Radiation now? We seem to have very similar illnesses so I have an idea of what your going through. Best of luck!

Right

now, I'm on IV Rocephin, Septra DS and IV Zithromycin and some supplements. I was doing really well and except for

fractured sleep, was feeling normal on most days from

November - mid January. In January, I underwent

a nine-hour breast cancer surgery. It

destroyed my innards and bladder (a relapse of symptoms). That's when the IV Zith was added. It stopped the stomach pain in two days. I won't be on that too long and hopefully,

will recover quickly. I have another

surgery in April.

BTW,

your doctor is horribly misinformed; misinformed enough to kill you.

Val

From: hyperaldosteronism

[mailto:hyperaldosteronism ] On Behalf Of Txsgreen

What

are you taking for your lymes? I'm having trouble finding a dr that believes

lymes doesn't just go away after one treatment. Thanks Val

JaNelle

Taking spiro did nothing for my resistant

weight. Getting Lyme treatment did. I've lost 29 pounds since last

June. For me, that's remarkable. Spiro and Inspra, BTW, did nothing

in terms of helping me feel better, cutting the "brittles," etc.

F, Lyme disease 24.5 years before diagnosis,

hypothyroid, hyperparathyroid, PA, BC, on Inspra 75 mg, several antibiotics.

From: hyperaldosteronism

[mailto:hyperaldosteronism ] On Behalf Of msmith_1928

Thanks Val, I've already done that, but would really be interested in

hearing the real-life experiences of others on this forum.

I've heard a few stories about weight *gain* after diagnosis, either after

starting meds or after adrenalectomy, and that is the last thing I am hoping

for! I'm hopeful that treating the PA will help treat the IR, but I haven't

seen much evidence of this.

- msmith1928

45, female, 5'3", 120 lbs, 1cm left adrenal nodule, aldosterone 42.3,

renin 0.5, potassium <2.9 (when not taking supplements); 25mg spiro caused

gynecomastia

[Guest guest]

Lots

to read here:  http://www.ilads.org/

You

have to find a Lyme-literate MD.  Few of

the rest get it.  I'm betting if you got

good tests through IgeneX, you'd be positive.

Val

From: hyperaldosteronism

[mailto:hyperaldosteronism ] On Behalf Of Txsgreen

I think I got lymes when I was a child. Wasn't diagnosed til

mid 30's. Only found out I had it because my brothers cardiologist diagnosed

him and said he should tel his family to check. My mother and I tested and were

positive. Unfortunatly I haven't found a dr that believes long term lymes needs

treatment. They had no problem saying it's RA, chronic fatigue, fibromyalgia

etc. Though I notice I feel the best when I am on antibiotics but getting a dr

to treat lymes arghhhh

[Guest guest]

Lyme

is found in every state in the U.S. and in every foreign country.  CDC admits that the actual incidence is 10 -

12 times greater than what is reported.

I had

a bilateral with DIEP flap reconstruction.  Yes, it was an horrific surgery.  No radiation, no chemo.  It was multi-focal but the only invasive

component was a tiny 1.7 mm spot. 

Val

From: hyperaldosteronism

[mailto:hyperaldosteronism ] On Behalf Of Txsgreen

Thank

you for the info. I'll keep trying to get treated. I'm in Texas now so they are

even less informed since it's not a 'local' illness. I find that when a dr

doesn't know something they would rather belittle you than educate themselves.

Well obviously not all Drs but too many of them. I've had Drs that encouraged

me to learn as much about my illness as possible then you have the ones who

won't even let you have a copy of your own labs

Best

of luck to you ,Val. That is one horrific surgery. Are you cancer free now?

Radiation now? We seem to have very similar illnesses so I have an idea of what

your going through. Best of luck!

Right now, I'm on IV Rocephin, Septra DS and IV

Zithromycin and some supplements. I was doing really well and except for

fractured sleep, was feeling normal on most days from November -

mid January. In January, I underwent a nine-hour breast cancer

surgery. It destroyed my innards and bladder (a relapse of

symptoms). That's when the IV Zith was added. It stopped the

stomach pain in two days. I won't be on that too long and hopefully, will

recover quickly. I have another surgery in April.

BTW, your doctor is horribly misinformed; misinformed

enough to kill you.

[Guest guest]

I am trying to find a doctor who will listen to your recommendations. After that I will definitely hire you.

To: hyperaldosteronism Cc: Clarence Grim Sent: Tue, March 1, 2011 8:57:24 PMSubject: Re: Re: PA, insulin resistance/metabolic syndrome, and weight gain

That is what I do. I can train you and your current team to do this right without going to a bunch of folks you don't know and who likely don't know about AME or Liddle's.

Hire me and save time and $.

CE Grim MD

Completely agree again. And since I don't eat a lot of salt, then, probably, AME or Liddle's.

I am trying to read about about both diseases and I am trying to find a good doctor, who will believe me and then you.

Many thanks.

Natalia

To: hyperaldosteronism Cc: Clarence Grim Sent: Mon, February 28, 2011 11:14:20

PMSubject: Re: Re: PA, insulin resistance/metabolic syndrome, and weight gain

You have an adrenal bump (we dont know if it is fat or muscle or what) and are likely eating a lot of salt that suppresses renin and aldo or have AME or Liddle's syndrome.

The spiro response suggests one of the last 2 as would not work just with excess salt.

We need to get you to a good Dr. who can help.

CE Grim MD

I have adrenal tumor, very low renin, low aldo and high cortisol and I am also diabetic.So, I am an example. When I started eplerenone and dropped many other BP medications, my sugar is much better now (changed from 150 in the morning to 120 in average). I also dropped two diabetes medications. But I am not sure whether it's DASH, droppind bad for me medications or eplerenone, what caused this effect.

Natalia Kamneva 66 Russian F with 1.5 cm adrenal adenoma, HTN and low renin , low aldosteron and high cortisol, K=3.4; diabetic.

To: hyperaldosteronism Sent: Sun, February 27, 2011 11:28:28 AMSubject: Re: PA, insulin resistance/metabolic syndrome, and weight gain

Thanks Dr. Grim! A Dr. Conn reader is a great idea :)Can an adrenal tumor cause both high aldo *and* high cortisol? I haven't had my cortisol measured but am starting to think it might be a good idea.> > > I see a lot of posts here in which weight gain is an issue for people, and thought this was worth discussing.> > > > I've found a lot of medical studies proposing a link between PA and insulin resistance/metabolic syndrome. For me, the first time that something was amiss was probably sudden weight *gain*

- after a lifetime of being underweight, I gained 50 pounds in one year and was diagnosed with insulin resistance, long before I ever was diagnosed with HTN or PA. (Check the Files section for "msmith1928's story" for more.)> > > > Via dietary changes I lost the weight really quickly and have kept it off for almost 10 years now. However, I remain really susceptible to weight gain, mostly from medications.> > > > I'm wondering if others with PA have had issues with weight that came on suddenly. I've seen references to the adrenals controlling sugar metabolism, such as this:http://www.umm.edu/general_surgery/lap_adrenalectomy.htm, and I'm wondering if it can be said that adrenal tumors can contribute to or cause insulin resistance?> > > > - msmith1928> > 45, female, 5'3", 120 lbs, 1cm left adrenal nodule, aldosterone 42.3, renin 0.5, potassium <2.9 (when not taking supplements)> > > >>

[Guest guest]

Thank

you, Natalia.

Val

From: hyperaldosteronism

[mailto:hyperaldosteronism ] On Behalf Of Natalia Kamneva

I

sincerely wish you good luck!!!!! Be healthy!!!

Natalia

Lyme is found in every state

in the U.S. and in every foreign country. CDC admits that the actual

incidence is 10 - 12 times greater than what is reported.

I had a bilateral with DIEP flap reconstruction.

Yes, it was an horrific surgery. No radiation, no chemo. It

was multi-focal but the only invasive component was a tiny 1.7 mm spot.

Val