Re: Vitamin D deficiency and Hyperaldosteronism

[Guest guest]

I take 5,000 IU of Vitamin D3. I

increased it until my number was good.

You are not getting enough sunshine. See information at the http://www.vitamindcouncil.org/

Val

From: hyperaldosteronism

[mailto:hyperaldosteronism ] On Behalf Of airlinerg

I am deficient in Vitamin D as my value is 20 and should be

30 to 80.

Do I

need to take a vitamin D supplement in addition to Eplerenone?

What

about Calcium and Magnesium supplementation?

What

effect will this have on my blood pressure and hyperaldosteronism.

I am

always thirsty and always urinating.

I read some articles related to this issue but I do not

understand them.

Vitamin D deficiency in primary aldosteronism

http://www.thefreelibrary.com/Vitamin+D+deficiency+in+primary+aldosteronism*-a0144298842

and

Aldosteronism

& Vitamin D Deficiency

<

/div>

http://www.livestrong.com/article/167327-aldosteronism-vitamin-d-deficiency/

[Guest guest]

DASH for calcium and see whAt your dr recommends for u for vit DTiped sad Send form miiPhone ;-)May your pressure be low!CE Grim MDSpecializing in DifficultHypertension

I am deficient in Vitamin D as my value is 20 and should be 30 to 80. Do I need to take a vitamin D supplement in addition to Eplerenone? What about Calcium and Magnesium supplementation?What effect will this have on my blood pressure and hyperaldosteronism.I am always thirsty and always urinating.I read some articles related to this issue but I do not understand them.Vitamin D deficiency in primary aldosteronismhttp://www.thefreelibrary.com/Vitamin+D+deficiency+in+primary+aldosteronism*-a0144298842and Aldosteronism & Vitamin D

Deficiencyhttp://www.livestrong.com/article/167327-aldosteronism-vitamin-d-deficiency/Can you please advise?

[Guest guest]

My guess is that vit d does not interfer with channels. More likely a salt load. But can only know in u by repeating the experiment until it seems clear that it is a problem in you. Tiped sad Send form miiPhone ;-)May your pressure be low!CE Grim MDSpecializing in DifficultHypertension

WARNING on VITAMIN D & CCB:

While I was on HTN medications and the most effective one was CCB amlodipine, I started to take 1000 IU of vit D daily. After few weeks my doc noticed my BP was out of control. After few more weeks and contacting a specialist we discovered that vit D was interfering with calcium channels and hence blocking the effects of CCB amlodipine. I stopped 1000 IU D and went back to previous bp results and contented myself with the much lower amounts in other multi-vitamin tablets.

Max.

I take 5,000 IU of Vitamin D3. I increased it until my number was good. You are not getting enough sunshine. See information at the http://www.vitamindcouncil.org/

Val

From: hyperaldosteronism [mailto:hyperaldosteronism ] On Behalf Of airlinerg

I am deficient in Vitamin D as my value is 20 and should be 30 to 80.

Do I need to take a vitamin D supplement in addition to Eplerenone?

What about Calcium and Magnesium supplementation?

What effect will this have on my blood pressure and hyperaldosteronism.

I am always thirsty and always urinating.

[Guest guest]

Vitamin D and drug interactions:

Several medications can interact with vitamin D. Check with your medical provider before you add vitamin D supplements to your diet if you are taking any medications, especially:

Anti-seizure medications, such as phenobarbital (Luminal), primidone (Mysoline) or valproic acid (Depakene, Depakote)

Calcium-channel blockers, such as Cardizem (diltiazem) and Norvasc (amlodipine)

Corticosteroids, such as prednisone

Older cholesterol-lowering medications that interfere with fat metabolism, such as cholestyramine (Questran)

Thiazide diuretics, such as Diuril (chlorothiazide) and Enduron (methyclothiazide), which could cause high calcium levels

X en ica l or(listat) (over-the-counter known as Alli)

Ref: Vitamin D and Menopause

[Guest guest]

Amlo isn't a drug that is sold in the USA.

>

> Yes I have PA due to left adenoma based on Scintiscan. It appears from the

published research that Amlo also has Aldo lowering effects in addition to other

beneficial effects as published. Otherwise, I was planning to ask my doc to get

me off Amlo as well as Indapamide. So still I am not sure what to do and

appreciate all suggestions.

>

> Max.

>

>

>

> Max u are on a very low dose of Spiro if u have PA. The goal is to control BP

with DASH and Spiro/eplerenone. Usually do not need other meds.

>

[Guest guest]

Amlo is 4th generation CCB and I found many good reported studies on its

function.

|

|Amlo isn't a drug that is sold in the USA.

|

[Guest guest]

Did find it is Norvasc or Amlodipine.

>

> Amlo is 4th generation CCB and I found many good reported studies on its

> function.

>

> |

> |Amlo isn't a drug that is sold in the USA.

> |

>

[Guest guest]

Another 4th generation CCB is Lacidipine...is that available in USA? I don't

know where it is found.

|

|

|Did find it is Norvasc or Amlodipine.

|

[Guest guest]

AmlodipineTiped sad Send form miiPhone ;-)May your pressure be low!CE Grim MDSpecializing in DifficultHypertension

Amlo is 4th generation CCB and I found many good reported studies on its

function.

|

|Amlo isn't a drug that is sold in the USA.

|

[Guest guest]

I recommend as few drugs as possible. Well and DASHING Tiped sad Send form miiPhone ;-)May your pressure be low!CE Grim MDSpecializing in DifficultHypertension

Amlo isn't a drug that is sold in the USA.

>

> Yes I have PA due to left adenoma based on Scintiscan. It appears from the published research that Amlo also has Aldo lowering effects in addition to other beneficial effects as published. Otherwise, I was planning to ask my doc to get me off Amlo as well as Indapamide. So still I am not sure what to do and appreciate all suggestions.

>

> Max.

>

>

>

> Max u are on a very low dose of Spiro if u have PA. The goal is to control BP with DASH and Spiro/eplerenone. Usually do not need other meds.

>

[Guest guest]

Dr. Grim and others:I wish you would stop giving abbreviations and spell out what you have to say, because we do not all know what the abbreviations mean.What is MCB?In the future, please spell everything out.> > >> > > > > > WARNING on VITAMIN D & CCB:> > > > > > While I was on HTN medications and the most effective one was CCB> > > amlodipine, I started to take 1000 IU of vit D daily. After few weeks my doc> > > noticed my BP was out of control. After few more weeks and contacting a> > > specialist we discovered that vit D was interfering with calcium channels> > > and hence blocking the effects of CCB amlodipine. I stopped 1000 IU D and> > > went back to previous bp results and contented myself with the much lower> > > amounts in other multi-vitamin tablets.> > > > > > Max.> > > > > > > I take 5,000 IU of Vitamin D3. I increased it until my number was good. You> > > are not getting enough sunshine. See information at the> > > http://www.vitamindcouncil.org/> > > > > > Val> > > > > > From: hyperaldosteronism > > > [mailto:hyperaldosteronism ] On Behalf Of airlinerg> > > > > > > > > I am deficient in Vitamin D as my value is 20 and should be 30 to 80. > > > > > > Do I need to take a vitamin D supplement in addition to Eplerenone? > > > > > > What about Calcium and Magnesium supplementation?> > > > > > What effect will this have on my blood pressure and hyperaldosteronism.> > > > > > I am always thirsty and always urinating.> > >> >>

[Guest guest]

We have an extensive list of abbreviations which will help learn this new language. MCB mineralocorticoid blocker. Tiped sad Send form miiPhone ;-)May your pressure be low!CE Grim MDSpecializing in DifficultHypertension

Dr. Grim and others:I wish you would stop giving abbreviations and spell out what you have to say, because we do not all know what the abbreviations mean.What is MCB?In the future, please spell everything out.> > >> > > > > > WARNING on VITAMIN D & CCB:> > > > > > While I was on HTN medications and the most effective one was CCB> > > amlodipine, I started to take 1000 IU of vit D daily. After few weeks my doc> > > noticed my BP was out of control. After few more weeks and contacting a> > > specialist we discovered that vit D was interfering with calcium channels> >

> and hence blocking the effects of CCB amlodipine. I stopped 1000 IU D and> > > went back to previous bp results and contented myself with the much lower> > > amounts in other multi-vitamin tablets.> > > > > > Max.> > > > > > > I take 5,000 IU of Vitamin D3. I increased it until my number was good. You> > > are not getting enough sunshine. See information at the> > > http://www.vitamindcouncil.org/> > > > > > Val> > > > > > From: hyperaldosteronism > > > [mailto:hyperaldosteronism ] On Behalf Of airlinerg> > > > > > > > > I am deficient in Vitamin D as my value is 20 and should be 30 to 80. > > > > > > Do I need to take a vitamin D supplement in addition to Eplerenone? > > > > > > What

about Calcium and Magnesium supplementation?> > > > > > What effect will this have on my blood pressure and hyperaldosteronism.> > > > > > I am always thirsty and always urinating.> > >> >>

[Guest guest]

Would be good to see data in man. Tiped sad Send form mildiPhone ;-)May your pressure be low!CE Grim MDSpecializing in DifficultHypertension

Calcium Channel Blockers

:: En Español (Spanish Version)

Page Navigation Calcium and Vitamin D —Possible Decreased Action of Drug Ginkgo Biloba —Possible Decreased Action of Drug Naringen (a Citrus Bioflavonoid)—May Necessitate Reduction of Drug Dosage

Calcium channel–blockers are used to treat :: hypertension , :: angina , :: heart arrhythmias , and other heart-related conditions.

Examples of drugs in this family include:

Amlodipine (Norvasc)

Bepridil hydrochloride (Vascor)

Diltiazem (Cardizem, Cardizem CD, Cardizem SR, Dilacor XR, Tiamate, Tiazac)

Felodipine (Plendil)

Isradipine (DynaCirc, DynaCirc CR)

Nicardipine hydrochloride (Cardene, Cardene SR)

Nifedipine (Procardia, Procardia XL, Adalat, Adalat CC)

Nimodipine (Nimotop)

Nisoldipine (Sular)

Verapamil (Calan, Calan SR, Covera-HS, Isoptin, Isoptin SR, Verelan)

:: Calcium and :: Vitamin D

Possible Decreased Action of Drug

Taking calcium and vitamin D supplements might interfere with some of the effects of calcium channel-blockers. 1-7

My guess is that vit d does not interfer with channels. More likely a salt load. But can only know in u by repeating the experiment until it seems clear that it is a problem in you.

[Guest guest]

In my experience, most of them don't know anything. Hyperaldosteronism is just a word, and they have never treated a patient with it. When you say Dash Diet or low salt diet, they shrug their shoulders and say maybe.That is the sad state of our medical system - 5 minutes to explain to your doctor your symptoms, and then they try to treat the symptoms and they never get to the cause.So Dr. Grim, I would appreciate it if you'd stop telling me to ask my doctor. I have several of them, and I always ask them before posting on here, and if they knew the answer and it was correct, I would not be asking on here.You answer every question I ask with: "Ask your doctor and DASH"Stop telling me that once and for all. I am smart enough not to be told more than once and I am already aware of these things. If you don't have anything additional to add to my questions, please do not answer them. I'll leave it for the other members of this group.>> based on my doc, I say: Even your dr may not know! [better to see a PhD specialist at your university or university hospital]> > Only your dr knows for sure.>

[Guest guest]

Most Dr have treated patients with Hyperaldosteronism

just not in the right way. At least 10% of those with high blood pressure have

Hyperaldosteronism.

> >

> > based on my doc, I say: Even your dr may not know! [better to see a

> PhD specialist at your university or university hospital]

> >

> > Only your dr knows for sure.

> >

>

[Guest guest]

So, do you suppose sunshine

would do the same thing?

Val

From: hyperaldosteronism

[mailto:hyperaldosteronism ] On Behalf Of StudyCircle

WARNING on VITAMIN

D & CCB:

While I was on HTN medications and the most effective one was CCB

amlodipine, I started to take 1000 IU of vit D daily. After few weeks my

doc noticed my BP was out of control. After few more weeks and contacting a

specialist we discovered that vit D was interfering with calcium channels and

hence blocking the effects of CCB amlodipine. I stopped 1000 IU D and went back

to previous bp results and contented myself with the much lower amounts in

other multi-vitamin tablets.

Max.

I take 5,000 IU of Vitamin D3. I increased it until my

number was good. You are not getting enough sunshine. See

information at the http://www.vitamindcouncil.org/

Val

From:

hyperaldosteronism [mailto:hyperaldosteronism ] On

Behalf Of airlinerg

I am deficient in Vitamin D as my value is 20 and should be 30 to 80.

Do

I need to take a vitamin D supplement in addition to Eplerenone?

What

about Calcium and Magnesium supplementation?

What

effect will this have on my blood pressure and hyperaldosteronism.

I

am always thirsty and always urinating.

[Guest guest]

I don't believe anything but

spiro or Inspra will stop the left ventricular damage of hyperaldo.

Val

From: hyperaldosteronism

[mailto:hyperaldosteronism ] On Behalf Of StudyCircle

Yes I have PA due to left adenoma based on Scintiscan. It

appears from the published research that Amlo also has Aldo lowering effects in

addition to other beneficial effects as published. Otherwise, I was planning to

ask my doc to get me off Amlo as well as Indapamide. So still I am not sure

what to do and appreciate all suggestions.

Max.

Max

u are on a very low dose of Spiro if u have PA. The goal is to control BP with

DASH and Spiro/eplerenone. Usually do not need other meds.

[Guest guest]

Damn! I did not look for sunshine effects in those published research about vit D+CCB. I have to review them again.

Max.

So, do you suppose sunshine would do the same thing?

Val

[Guest guest]

Here is a nice research on Sunshine, VitaminD, and CVD:

The "Sunshine Deficit" and Cardiovascular Disease

So, do you suppose sunshine would do the same thing?

Val

[Guest guest]

And DASHING. NO salt no HTN NO LVHTiped sad Send form miiPhone ;-)May your pressure be low!CE Grim MDSpecializing in DifficultHypertension

I don't believe anything but

spiro or Inspra will stop the left ventricular damage of hyperaldo.

Val

From: hyperaldosteronism

[mailto:hyperaldosteronism ] On Behalf Of StudyCircle

Yes I have PA due to left adenoma based on Scintiscan. It

appears from the published research that Amlo also has Aldo lowering effects in

addition to other beneficial effects as published. Otherwise, I was planning to

ask my doc to get me off Amlo as well as Indapamide. So still I am not sure

what to do and appreciate all suggestions.

Max.

Max

u are on a very low dose of Spiro if u have PA. The goal is to control BP with

DASH and Spiro/eplerenone. Usually do not need other meds.

[Guest guest]

I tend to think a decent vitamin

D level is advantageous, but enough sunshine for most is not attainable. The Vitamin D Council has lots of

research in one location. If

Vitamin D increases BP, you would know it if you take a daily reading and

average it over a few days. Lyme

treatment has dropped my med level by 75%.

I didn't notice any increase with Vitamin D. My Lyme doc has me on 5,000 IU and that

gives me a perfect number. It

varies between 53 and 76.

BTW, I'm getting liver tests

every two weeks. You'd be amazed

that the variance between labs. One

hospital lab had a 30% variance depending on the location.

Val

From: hyperaldosteronism

[mailto:hyperaldosteronism ] On Behalf Of StudyCircle

Here is a nice research on Sunshine, VitaminD, and CVD:

The

" Sunshine Deficit " and Cardiovascular Disease

So, do you suppose

sunshine would do the same thing?

Val

..

[Guest guest]

Hi, I don't know much about these minerals/vitamins and their effect on hyperaldosteronism, but I do know that anytime you supplement vitamin D you also want to supplement magnesium. Supplementing vitamin D alone will "eat up" all your magnesium. Vitamin D might also have the same effect on calcium but I do not know if this is true or not.I personally supplement vitamin D and magnesium but not calcium. In my opinion magnesium is of great importance in many bodily functions and lacking in our diet/food supply.Good luck to you.Sent from my iPad

My deficiency of Vitamin D may not be from diet nor from low sun exposure.I am asking these 3 questions if anybody knows the answers:1. Do I need to take a vitamin D supplement?2. How can I know if I need Calcium and Magnesium supplement?3. What effect will increasing these vitamins and minerals have on my blood pressure and hyperaldosteronism?Please reply.This article Vitamin D deficiency in primary aldosteronismhttp://www.thefreelibrary.com/Vitamin+D+deficiency+in+primary+aldosteronism*-a0144298842suggests: Of interest, the presence of vitamin D deficiency in salt-sensitive hypertension of primary aldosteronism suggests that primary aldosteronism might have a role in

inducing vitamin D deficiency. and This article Aldosteronism & Vitamin D Deficiencyhttp://www.livestrong.com/article/167327-aldosteronism-vitamin-d-deficiency/ suggests:A

study in the December 2008 "Journal of the American College of Cardiology" reported that vitamin D deficiency is prevalent in approximately 30 to 50 percent of the general population and because it is associated with the elevation of renin, angiotensin 2 and aldosterone levels it is a risk factor for hypertension and other cardiovascular dysfunctions.and There is little evidence that supports vitamin D deficiency directly causes aldosteronism. However, a case report published in the Dec. 1, 2006, "Southern Medical Journal" noted that the two conditions have occurred in an individual simultaneously. Additionally, animal studies have revealed that vitamin D increases renin levels.> > > I am deficient in Vitamin D as my value is 20 and should be 30 to 80. > > > > > > Do I need to take a vitamin D supplement in addition to Eplerenone? > > > > What about Calcium and Magnesium supplementation?> > > > What effect will this have on my blood pressure and hyperaldosteronism.> > > > I am always thirsty and always urinating.> > > > > > > > I read some articles related to this issue but I do not understand them.> > > > Vitamin D deficiency in primary aldosteronism> > > > > > http://www.thefreelibrary.com/Vitamin+D+deficiency+in+primary+aldosteronism*-a0144298842> > > > and > > > > Aldosteronism & Vitamin D Deficiency> > > > > > http://www.livestrong.com/article/167327-aldosteronism-vitamin-d-deficiency/> > > > Can you please advise?> > > > > >>

[Guest guest]

We trust opinion by must verify with data to paraphrase the great communicator-RRTiped sad Send form miiPhone ;-)May your pressure be low!CE Grim MDSpecializing in DifficultHypertension

Hi, I don't know much about these minerals/vitamins and their effect on hyperaldosteronism, but I do know that anytime you supplement vitamin D you also want to supplement magnesium. Supplementing vitamin D alone will "eat up" all your magnesium. Vitamin D might also have the same effect on calcium but I do not know if this is true or not.I personally supplement vitamin D and magnesium but not calcium. In my opinion magnesium is of great importance in many bodily functions and lacking in our diet/food supply.Good luck to you.Sent from my iPad

My deficiency of Vitamin D may not be from diet nor from low sun exposure.I am asking these 3 questions if anybody knows the answers:1. Do I need to take a vitamin D supplement?2. How can I know if I need Calcium and Magnesium supplement?3. What effect will increasing these vitamins and minerals have on my blood pressure and hyperaldosteronism?Please reply.This article Vitamin D deficiency in primary aldosteronismhttp://www.thefreelibrary.com/Vitamin+D+deficiency+in+primary+aldosteronism*-a0144298842suggests: Of interest, the presence of vitamin D deficiency in salt-sensitive hypertension of primary aldosteronism suggests that primary aldosteronism might have a role in

inducing vitamin D deficiency. and This article Aldosteronism & Vitamin D Deficiencyhttp://www.livestrong.com/article/167327-aldosteronism-vitamin-d-deficiency/ suggests:A

study in the December 2008 "Journal of the American College of Cardiology" reported that vitamin D deficiency is prevalent in approximately 30 to 50 percent of the general population and because it is associated with the elevation of renin, angiotensin 2 and aldosterone levels it is a risk factor for hypertension and other cardiovascular dysfunctions.and There is little evidence that supports vitamin D deficiency directly causes aldosteronism. However, a case report published in the Dec. 1, 2006, "Southern Medical Journal" noted that the two conditions have occurred in an individual simultaneously. Additionally, animal studies have revealed that vitamin D increases renin levels.> > > I am deficient in Vitamin D as my value is 20 and should be 30 to 80. > > > > > > Do I need to take a vitamin D supplement in addition to Eplerenone? > > > > What about Calcium and Magnesium supplementation?> > > > What effect will this have on my blood pressure and hyperaldosteronism.> > > > I am always thirsty and always urinating.> > > > > > > > I read some articles related to this issue but I do not understand them.> > > > Vitamin D deficiency in primary aldosteronism> > > > > > http://www.thefreelibrary.com/Vitamin+D+deficiency+in+primary+aldosteronism*-a0144298842> > > > and > > > > Aldosteronism & Vitamin D Deficiency> > > > > > http://www.livestrong.com/article/167327-aldosteronism-vitamin-d-deficiency/> > > > Can you please advise?> > > > > >>

[Guest guest]

calcium and vit.D acts together. from abbie

I tend to think a decent vitamin

D level is advantageous, but enough sunshine for most is not attainable. The Vitamin D Council has lots of

research in one location. If

Vitamin D increases BP, you would know it if you take a daily reading and

average it over a few days. Lyme

treatment has dropped my med level by 75%.

I didn't notice any increase with Vitamin D. My Lyme doc has me on 5,000 IU and that

gives me a perfect number. It

varies between 53 and 76. BTW, I'm getting liver tests

every two weeks. You'd be amazed

that the variance between labs. One

hospital lab had a 30% variance depending on the location. Val From: hyperaldosteronism

[mailto:hyperaldosteronism ] On Behalf Of StudyCircle

Here is a nice research on Sunshine, VitaminD, and CVD:

The

"Sunshine Deficit" and Cardiovascular Disease

So, do you suppose

sunshine would do the same thing? Val

..

[Guest guest]

is it really true max and Dr. Grim that amlodipine can also lower the hyperaldosterone? from abbie

I don't believe anything but

spiro or Inspra will stop the left ventricular damage of hyperaldo. Val From: hyperaldosteronism

[mailto:hyperaldosteronism ] On Behalf Of StudyCircle

Yes I have PA due to left adenoma based on Scintiscan. It

appears from the published research that Amlo also has Aldo lowering effects in

addition to other beneficial effects as published. Otherwise, I was planning to

ask my doc to get me off Amlo as well as Indapamide. So still I am not sure

what to do and appreciate all suggestions.

Max.

Max

u are on a very low dose of Spiro if u have PA. The goal is to control BP with

DASH and Spiro/eplerenone. Usually do not need other meds.