Re: High glutamate and neuronal death

September 28, 2007

I

don’t think she does, at least not in the book. Having said that I think

she is right. No idea why, just instinct, no science. Stopping L glutamine seemed

to help Tom a bit. Adding GABA was a big big wow. Stopping

Calcium was also a massive WOW for us. So my instincts say she’s probably

right. It annoys me that she’s out on a limb though. I wonder why there’s

not more dialogue with DAN!

Sara

-----Original

Message-----

From:

Autism-Biomedical-Europe

[mailto:Autism-Biomedical-Europe ] On Behalf Of Zoe

Sent: 28

September 2007

09:46

To:

Autism-Biomedical-Europe

Subject:

Re: High glutamate and neuronal death

Good point Sally. I wonder if Yasko does explain it somewhere?

Does anyone have her explanation of the DAN interpretation of the

chemistry involved?

Zoe

> > > >

> > > > Hi Peta,

> > > >

> > > > Amy Yasko is really keen about reducing glutamates and

> > supplementing

> > > > a small amount of Gaba.

> > > >

> > > > As well as avoiding overly glutamate foods this also means

NOT

> > > > supplementing L-gluatime or using alpha keto glutarates

etc.

I

> > > > can't find a good summary on-line - I'll paste what I could

find

> > > > below. We were supplementing l-glutamine a lot before and

were

> > slow

> > > > to reduce and then remove it - but Eddie's glutamine/gaba

have

> > > > actually balanced out. So while we were supplementing he

was

low

> > and

> > > > when we stopped he improved. The more I learn the more I

like

> > Yasko -

> > > > it is doing great things for Eddie.

> > > >

> > > > Best wishes,

> > > > Sandy

> > > >

> > > > http://forums. <http://forums. about.com/ n/pfx/forum. aspx?

> > <http://forums.about.com/n/pfx/forum.aspx?>>

> > > about.com/n/ pfx/forum. aspx?

> > > > nav=printDiscussion & webtag=ab- autism & tid= 4426

> > > > COPIED from this link ....

> > > > FYI, Here is some of what Dr Amy Yasko says about glutamate

> > in " The

> > > > Puzzle of Autism: Putting it all Together " : (pgs 8-9)

> > > >

> > > > " Glutamate is the main excitatory neurotransmitter in

the

body.

> > It is

> > > > essential for learning and for both short-term and

long-term

> > memory.

> > > > It is also the precursor to the inhibitory

neurotransmitter,

GABA.

> > > > GABA is a calming neurotransmitter and is essential for

speech.

> > GABA

> > > > neurons damp the propagation of sounds so that a

distinction

can

> > be

> > > > made between the onset of a sound and background

noise....Problems

> > > > occur if the normal process of regulation of glutamate

> > malfunctions

> > > > and if toxic levels of this excitatory neurotransmitter

build up

> > in

> > > > the synaptic junctions.

> > > > The balance between glutamate and GABA is like a seesaw.

Under

> > normal

> > > > conditions, when the glutamate side gets too high, the GABA

side

> > of

> > > > the seesaw will increase and decrease the glutamate. Under

normal

> > > > functioning conditions, excess levels of the excitotoxin

glutamate

> > > > will convert to GABA. There seems to be a

" disconnect " in

this

> > > > process for autistic children so that the excitatory

> > > > neurotransmission is high (stims) and the calming

> > neurotransmission

> > > > is low (lack of speech). When conditions occur that throw

off this

> > > > delicate balance, then high levels of glutamate can

accumulate

> > while

> > > > the levels of GABA remain exceedingly low. This would

create

a

> > > > situation that would require decreasing the glutamate

levels, and

> > > > increasing the GABA levels in order to restore balance.

Chronic

> > viral

> > > > infection may be related to this disconnect between

glutamate and

> > > > GABA. "

> > > >

> > > > " Over seven years ago, Dr Blaylock described

the

pathway

> > of

> > > > excitotoxin damage and the role it plays in neurological

damage

> > > > brilliantly in his landmark book on excitotoxins. He

spelled

out

> > > > specifically how and why MSG, hydrolyzed vegetable protein,

> > aspartame

> > > > and related compounds have been proven to cause death of

neurons

> > > > beyond any reasonable doubt. More recently, this concept of

> > > > excitotoxin damage has been found to pertain to autism.

> > Excitotoxins

> > > > are neurotransmitters such as glutamate or aspartate

> > > > that can excite the nerves to death when their levels are

not

> > > > regulated properly. Foods or supplements that contain

excitotoxins

> > > > include MSG, glutamic acid, glutamine, Nutra Sweet,

aspartate,

> > > > aspartame and cysteine. Mercury and aluminum can trigger

glutamate

> > > > release. Minimizing glutatmate is a differentiating factor

in our

> > > > protocol and has helped many autistic children

significantly. "

> > > >

> > >

> >

> > ----------------------------------------------------------

-------

> >

> > No virus found in this incoming message.

> > Checked by AVG Free Edition.

> > Version: 7.5.488 / Virus Database: 269.13.30/1030 - Release

Date: 25/09/2007 08:02

> >

>

September 28, 2007

Hi Sara,

Thank you so much, it does help in a way to know that there is

" disagreement " between them about it's use, that spells caution. We

tried it for just under two weeks, we had some increase in seizures

together with increased thirst and wee and strong ketone breath, got

scared and stopped. It is very difficult to determine if this was the

cause as son's seizures are very hard to manage and very unpredictable

with ups and downs all the time.

His glutamic acid was high at 222 (ref range 101-308) and his

glutamine much lower at 389 (ref range 208-612) on the amino acid blood

spot test. I wondered if this in anyway indicated that he has got

difficulty in converting glutamic acid to glutamine ?!!!

emily x

> >

> > Hi Peta,

> >

> > Amy Yasko is really keen about reducing glutamates and supplementing

> > a small amount of Gaba.

> >

> > As well as avoiding overly glutamate foods this also means NOT

> > supplementing L-gluatime or using alpha keto glutarates etc. I

> > can't find a good summary on-line - I'll paste what I could find

> > below. We were supplementing l-glutamine a lot before and were slow

> > to reduce and then remove it - but Eddie's glutamine/gaba have

> > actually balanced out. So while we were supplementing he was low and

> > when we stopped he improved. The more I learn the more I like Yasko

-

> > it is doing great things for Eddie.

> >

> > Best wishes,

> > Sandy

> >

> > http://forums. <http://forums.about.com/n/pfx/forum.aspx?>

> about.com/n/pfx/forum.aspx?

> > nav=printDiscussion & webtag=ab-autism & tid=4426

> > COPIED from this link ....

> > FYI, Here is some of what Dr Amy Yasko says about glutamate in " The

> > Puzzle of Autism: Putting it all Together " : (pgs 8-9)

> >

> > " Glutamate is the main excitatory neurotransmitter in the body. It

is

> > essential for learning and for both short-term and long-term memory.

> > It is also the precursor to the inhibitory neurotransmitter, GABA.

> > GABA is a calming neurotransmitter and is essential for speech. GABA

> > neurons damp the propagation of sounds so that a distinction can be

> > made between the onset of a sound and background noise....Problems

> > occur if the normal process of regulation of glutamate malfunctions

> > and if toxic levels of this excitatory neurotransmitter build up in

> > the synaptic junctions.

> > The balance between glutamate and GABA is like a seesaw. Under

normal

> > conditions, when the glutamate side gets too high, the GABA side of

> > the seesaw will increase and decrease the glutamate. Under normal

> > functioning conditions, excess levels of the excitotoxin glutamate

> > will convert to GABA. There seems to be a " disconnect " in this

> > process for autistic children so that the excitatory

> > neurotransmission is high (stims) and the calming neurotransmission

> > is low (lack of speech). When conditions occur that throw off this

> > delicate balance, then high levels of glutamate can accumulate while

> > the levels of GABA remain exceedingly low. This would create a

> > situation that would require decreasing the glutamate levels, and

> > increasing the GABA levels in order to restore balance. Chronic

viral

> > infection may be related to this disconnect between glutamate and

> > GABA. "

> >

> > " Over seven years ago, Dr Blaylock described the pathway of

> > excitotoxin damage and the role it plays in neurological damage

> > brilliantly in his landmark book on excitotoxins. He spelled out

> > specifically how and why MSG, hydrolyzed vegetable protein,

aspartame

> > and related compounds have been proven to cause death of neurons

> > beyond any reasonable doubt. More recently, this concept of

> > excitotoxin damage has been found to pertain to autism. Excitotoxins

> > are neurotransmitters such as glutamate or aspartate

> > that can excite the nerves to death when their levels are not

> > regulated properly. Foods or supplements that contain excitotoxins

> > include MSG, glutamic acid, glutamine, Nutra Sweet, aspartate,

> > aspartame and cysteine. Mercury and aluminum can trigger glutamate

> > release. Minimizing glutatmate is a differentiating factor in our

> > protocol and has helped many autistic children significantly. "

> >

>

September 28, 2007

Hmmm.....if that quote was taken straight from Yaskos book, then it

says very clearly to me that she thinks her colleagues do not

understand the chemistry of what happens if glutamine is given as a

supplement.

She seems to be saying that glutamine would act as an excitotoxin

and therefore should not be given as a supplement.

It seems there is a dispute over this issue - one DAN Practitioner

has been quoted as saying L Glutamine does not affect glutamate

levels (but no explanation of this).

Lots of confusion amongst listmates (including myself) - can anyone

explain the two schools of thought here?

I have a murky memory of reading that glutamine doesnt get as far as

the brain (which is where an excitotoxin would affect, right?)

because it is all used up by the gut? I could be totally off the

wall here - am sure someone will know?

Thanks

Zoe

> > > > >

> > > > > Hi Peta,

> > > > >

> > > > > Amy Yasko is really keen about reducing glutamates and

> > > supplementing

> > > > > a small amount of Gaba.

> > > > >

> > > > > As well as avoiding overly glutamate foods this also means

> NOT

> > > > > supplementing L-gluatime or using alpha keto glutarates

etc.

> I

> > > > > can't find a good summary on-line - I'll paste what I

could

> find

> > > > > below. We were supplementing l-glutamine a lot before and

> were

> > > slow

> > > > > to reduce and then remove it - but Eddie's glutamine/gaba

> have

> > > > > actually balanced out. So while we were supplementing he

was

> low

> > > and

> > > > > when we stopped he improved. The more I learn the more I

like

> > > Yasko -

> > > > > it is doing great things for Eddie.

> > > > >

> > > > > Best wishes,

> > > > > Sandy

> > > > >

> > > > > http://forums. <http://forums. about.com/ n/pfx/forum.

aspx?

> > > <http://forums. <http://forums.about.com/n/pfx/forum.aspx?>

> about.com/n/pfx/forum.aspx?>>

> > > > about.com/n/ pfx/forum. aspx?

> > > > > nav=printDiscussion & webtag=ab- autism & tid= 4426

> > > > > COPIED from this link ....

> > > > > FYI, Here is some of what Dr Amy Yasko says about glutamate

> > > in " The

> > > > > Puzzle of Autism: Putting it all Together " : (pgs 8-9)

> > > > >

> > > > > " Glutamate is the main excitatory neurotransmitter in the

> body.

> > > It is

> > > > > essential for learning and for both short-term and long-

term

> > > memory.

> > > > > It is also the precursor to the inhibitory

neurotransmitter,

> GABA.

> > > > > GABA is a calming neurotransmitter and is essential for

> speech.

> > > GABA

> > > > > neurons damp the propagation of sounds so that a

distinction

> can

> > > be

> > > > > made between the onset of a sound and background

> noise....Problems

> > > > > occur if the normal process of regulation of glutamate

> > > malfunctions

> > > > > and if toxic levels of this excitatory neurotransmitter

> build up

> > > in

> > > > > the synaptic junctions.

> > > > > The balance between glutamate and GABA is like a seesaw.

> Under

> > > normal

> > > > > conditions, when the glutamate side gets too high, the

GABA

> side

> > > of

> > > > > the seesaw will increase and decrease the glutamate. Under

> normal

> > > > > functioning conditions, excess levels of the excitotoxin

> glutamate

> > > > > will convert to GABA. There seems to be a " disconnect " in

> this

> > > > > process for autistic children so that the excitatory

> > > > > neurotransmission is high (stims) and the calming

> > > neurotransmission

> > > > > is low (lack of speech). When conditions occur that throw

> off this

> > > > > delicate balance, then high levels of glutamate can

> accumulate

> > > while

> > > > > the levels of GABA remain exceedingly low. This would

create

> a

> > > > > situation that would require decreasing the glutamate

> levels, and

> > > > > increasing the GABA levels in order to restore balance.

> Chronic

> > > viral

> > > > > infection may be related to this disconnect between

> glutamate and

> > > > > GABA. "

> > > > >

> > > > > " Over seven years ago, Dr Blaylock described the

> pathway

> > > of

> > > > > excitotoxin damage and the role it plays in neurological

> damage

> > > > > brilliantly in his landmark book on excitotoxins. He

spelled

> out

> > > > > specifically how and why MSG, hydrolyzed vegetable protein,

> > > aspartame

> > > > > and related compounds have been proven to cause death of

> neurons

> > > > > beyond any reasonable doubt. More recently, this concept of

> > > > > excitotoxin damage has been found to pertain to autism.

> > > Excitotoxins

> > > > > are neurotransmitters such as glutamate or aspartate

> > > > > that can excite the nerves to death when their levels are

not

> > > > > regulated properly. Foods or supplements that contain

> excitotoxins

> > > > > include MSG, glutamic acid, glutamine, Nutra Sweet,

> aspartate,

> > > > > aspartame and cysteine. Mercury and aluminum can trigger

> glutamate

> > > > > release. Minimizing glutatmate is a differentiating factor

> in our

> > > > > protocol and has helped many autistic children

> significantly. "

> > > > >

> > > >

> > >

> > > ----------------------------------------------------------

> -------

> > >

> > > No virus found in this incoming message.

> > > Checked by AVG Free Edition.

> > > Version: 7.5.488 / Virus Database: 269.13.30/1030 - Release

> Date: 25/09/2007 08:02

> > >

> >

>

September 28, 2007

Hi Sara,

Me again pestering! What was the reason you used GABA and why do you

think stopping calcium helped? Sorry this is not coming out right

(tryin to figure out what I'm asking), how does the calcium fit into all

of this?

emily

> > > > >

> > > > > Hi Peta,

> > > > >

> > > > > Amy Yasko is really keen about reducing glutamates and

> > > supplementing

> > > > > a small amount of Gaba.

> > > > >

> > > > > As well as avoiding overly glutamate foods this also means

> NOT

> > > > > supplementing L-gluatime or using alpha keto glutarates etc.

> I

> > > > > can't find a good summary on-line - I'll paste what I could

> find

> > > > > below. We were supplementing l-glutamine a lot before and

> were

> > > slow

> > > > > to reduce and then remove it - but Eddie's glutamine/gaba

> have

> > > > > actually balanced out. So while we were supplementing he was

> low

> > > and

> > > > > when we stopped he improved. The more I learn the more I like

> > > Yasko -

> > > > > it is doing great things for Eddie.

> > > > >

> > > > > Best wishes,

> > > > > Sandy

> > > > >

> > > > > http://forums. <http://forums. about.com/ n/pfx/forum. aspx?

> > > <http://forums. <http://forums.about.com/n/pfx/forum.aspx?>

> about.com/n/pfx/forum.aspx?>>

> > > > about.com/n/ pfx/forum. aspx?

> > > > > nav=printDiscussion & webtag=ab- autism & tid= 4426

> > > > > COPIED from this link ....

> > > > > FYI, Here is some of what Dr Amy Yasko says about glutamate

> > > in " The

> > > > > Puzzle of Autism: Putting it all Together " : (pgs 8-9)

> > > > >

> > > > > " Glutamate is the main excitatory neurotransmitter in the

> body.

> > > It is

> > > > > essential for learning and for both short-term and long-term

> > > memory.

> > > > > It is also the precursor to the inhibitory neurotransmitter,

> GABA.

> > > > > GABA is a calming neurotransmitter and is essential for

> speech.

> > > GABA

> > > > > neurons damp the propagation of sounds so that a distinction

> can

> > > be

> > > > > made between the onset of a sound and background

> noise....Problems

> > > > > occur if the normal process of regulation of glutamate

> > > malfunctions

> > > > > and if toxic levels of this excitatory neurotransmitter

> build up

> > > in

> > > > > the synaptic junctions.

> > > > > The balance between glutamate and GABA is like a seesaw.

> Under

> > > normal

> > > > > conditions, when the glutamate side gets too high, the GABA

> side

> > > of

> > > > > the seesaw will increase and decrease the glutamate. Under

> normal

> > > > > functioning conditions, excess levels of the excitotoxin

> glutamate

> > > > > will convert to GABA. There seems to be a " disconnect " in

> this

> > > > > process for autistic children so that the excitatory

> > > > > neurotransmission is high (stims) and the calming

> > > neurotransmission

> > > > > is low (lack of speech). When conditions occur that throw

> off this

> > > > > delicate balance, then high levels of glutamate can

> accumulate

> > > while

> > > > > the levels of GABA remain exceedingly low. This would create

> a

> > > > > situation that would require decreasing the glutamate

> levels, and

> > > > > increasing the GABA levels in order to restore balance.

> Chronic

> > > viral

> > > > > infection may be related to this disconnect between

> glutamate and

> > > > > GABA. "

> > > > >

> > > > > " Over seven years ago, Dr Blaylock described the

> pathway

> > > of

> > > > > excitotoxin damage and the role it plays in neurological

> damage

> > > > > brilliantly in his landmark book on excitotoxins. He spelled

> out

> > > > > specifically how and why MSG, hydrolyzed vegetable protein,

> > > aspartame

> > > > > and related compounds have been proven to cause death of

> neurons

> > > > > beyond any reasonable doubt. More recently, this concept of

> > > > > excitotoxin damage has been found to pertain to autism.

> > > Excitotoxins

> > > > > are neurotransmitters such as glutamate or aspartate

> > > > > that can excite the nerves to death when their levels are not

> > > > > regulated properly. Foods or supplements that contain

> excitotoxins

> > > > > include MSG, glutamic acid, glutamine, Nutra Sweet,

> aspartate,

> > > > > aspartame and cysteine. Mercury and aluminum can trigger

> glutamate

> > > > > release. Minimizing glutatmate is a differentiating factor

> in our

> > > > > protocol and has helped many autistic children

> significantly. "

> > > > >

> > > >

> > >

> > > ----------------------------------------------------------

> -------

> > >

> > > No virus found in this incoming message.

> > > Checked by AVG Free Edition.

> > > Version: 7.5.488 / Virus Database: 269.13.30/1030 - Release

> Date: 25/09/2007 08:02

> > >

> >

>

September 28, 2007

L Glutamine was one of the better supplements we used with .

It was reccomended to me here yonks ago and alongside enzymes really contributed to his gut healing, he did fantastically well for yrs, didn't use it as an all the time thing but certainly helped in settling things down at the start.

Didn't see any behaviours from using it, if anything his behaviour imporved considerably from being free of pain.

>>We also used L-Glutamine years ago with Sam, can't say I saw anything good or bad in partticular because nothiing much was working before HNI - BUT when we first started on them, HNI contained Peptizyde contained L-Glutamine! It was removed after about 6 months because some were seeing hyperactivity and the L-Glutamine was considered the culprit by parents.

For behaviours almost always come with a gut problem.

There doesn't seem to be a hard and fast rule with much of this, or certainly not with my kid, since re-introducing Vit D his bowels are slowly getting better, Why

>>>because Vitamin D does all sorts of wonderful things, helping against virus is one and helping calciu transport is another - both of which I think has issues with . There is a great site about it all I think this is the one

http://www.vitamindcouncil.com/

Mandi x

September 28, 2007

Hi it sometimes seems to me that Yasko and DAN are not working

together which is sad. I think saying DAN dr's don't do this or

address that isn't right because the term DAN is an umbrella under

which there are good and not so good Dr's. I think we should try to

gain knowledge from all sources and question, question, question. I

haven't personally looked into Yasko because it sounds so damn

complicated but I'm sure that good DAN dr's and I'm sure Yasko as

well are open to new research. Those who stand still are not really

good dr's otherwise all our kids would be cured.

Just a thought!

Peta

- In Autism-Biomedical-Europe , " Sass and Rem " <Moroza-

@...> wrote:

>

> Hi ,

> In Yasko's book 'the puzzle of autism' she says 'Excitotoxins will

> continue to damage more nerves and wreak more havoc in the body if

they

> are not addressed.This is an area where we encounter disagreement

with

> some of our colleagues (she means DAN! here I assume).Due to a basic

> lack of understanding about the involved chemistry, we find that

> glutamic acid, glutamine, etc are still being included in supplement

> regimes for their potential gastro-intestinal benefits, while their

> documented potential for contributing to the proven neurotoxic

effects

> are being ignored. "

> Don't know if that helps but basically it says to me that DAN!

doctors

> and Yasko disagree on this.

> Sara

>

> Re: High glutamate and neuronal

> death

>

> Hi,

>

> Just butting in. L-Glutamine was recommended for DS I asked Lorene

> about it glutamine affecting/increasing the glutamate levels, she

said

> that it doesn't. I'm confused about this is anyone able to clarify

or

> point me to any reading material!

>

> thanks,

>

> emily

>

> >

> > Hi Peta,

> >

> > Amy Yasko is really keen about reducing glutamates and

supplementing

> > a small amount of Gaba.

> >

> > As well as avoiding overly glutamate foods this also means NOT

> > supplementing L-gluatime or using alpha keto glutarates etc. I

> > can't find a good summary on-line - I'll paste what I could find

> > below. We were supplementing l-glutamine a lot before and were

slow

> > to reduce and then remove it - but Eddie's glutamine/gaba have

> > actually balanced out. So while we were supplementing he was low

and

> > when we stopped he improved. The more I learn the more I like

Yasko -

> > it is doing great things for Eddie.

> >

> > Best wishes,

> > Sandy

> >

> > http://forums. <http://forums.about.com/n/pfx/forum.aspx?>

> about.com/n/pfx/forum.aspx?

> > nav=printDiscussion & webtag=ab-autism & tid=4426

> > COPIED from this link ....

> > FYI, Here is some of what Dr Amy Yasko says about glutamate

in " The

> > Puzzle of Autism: Putting it all Together " : (pgs 8-9)

> >

> > " Glutamate is the main excitatory neurotransmitter in the body.

It is

> > essential for learning and for both short-term and long-term

memory.

> > It is also the precursor to the inhibitory neurotransmitter, GABA.

> > GABA is a calming neurotransmitter and is essential for speech.

GABA

> > neurons damp the propagation of sounds so that a distinction can

be

> > made between the onset of a sound and background noise....Problems

> > occur if the normal process of regulation of glutamate

malfunctions

> > and if toxic levels of this excitatory neurotransmitter build up

in

> > the synaptic junctions.

> > The balance between glutamate and GABA is like a seesaw. Under

normal

> > conditions, when the glutamate side gets too high, the GABA side

of

> > the seesaw will increase and decrease the glutamate. Under normal

> > functioning conditions, excess levels of the excitotoxin glutamate

> > will convert to GABA. There seems to be a " disconnect " in this

> > process for autistic children so that the excitatory

> > neurotransmission is high (stims) and the calming

neurotransmission

> > is low (lack of speech). When conditions occur that throw off this

> > delicate balance, then high levels of glutamate can accumulate

while

> > the levels of GABA remain exceedingly low. This would create a

> > situation that would require decreasing the glutamate levels, and

> > increasing the GABA levels in order to restore balance. Chronic

viral

> > infection may be related to this disconnect between glutamate and

> > GABA. "

> >

> > " Over seven years ago, Dr Blaylock described the pathway

of

> > excitotoxin damage and the role it plays in neurological damage

> > brilliantly in his landmark book on excitotoxins. He spelled out

> > specifically how and why MSG, hydrolyzed vegetable protein,

aspartame

> > and related compounds have been proven to cause death of neurons

> > beyond any reasonable doubt. More recently, this concept of

> > excitotoxin damage has been found to pertain to autism.

Excitotoxins

> > are neurotransmitters such as glutamate or aspartate

> > that can excite the nerves to death when their levels are not

> > regulated properly. Foods or supplements that contain excitotoxins

> > include MSG, glutamic acid, glutamine, Nutra Sweet, aspartate,

> > aspartame and cysteine. Mercury and aluminum can trigger glutamate

> > release. Minimizing glutatmate is a differentiating factor in our

> > protocol and has helped many autistic children significantly. "

> >

>

September 28, 2007

Hello

,

I’m

probably the worst person in the world to explain this with my very

unscientific brain so I’ll copy a bit of Yasko’s book again…

“Glutamate

has six different types of receptors to which it can bind in the brain. One of

these receptors, the NMDA receptor, is tied to calcium transport as its mode of

action. In the case of the NMDA receptors, the release of excess glutamate

triggers an inflammatory cascade that results in the death of neurons by the

major influx of calcium into the nerve until it results in neural cell death. Normal

levels of calcium result in normal neuron functioning. However, excessive

levels of calcium make it impossible for the neuron to rest; the neuron continues

to fire without stopping causing the release of inflammatory mediators, the

release of more glutamate, thus resulting in more calcium influx. The high

intracellular levels of calcium also lead to high levels of nitric oxide and peroxynitrite,

causing damage to the energy producing apparatus of the cells. Magnesium (a

second part of Dr. Rimland’s protocol) is able to modulate the calcium

flow, as is zinc. However zinc is a double-edged sword as it is also able to

activate glutamate release via the non-NMDA glutamate receptors.”

On

the Vit k yahoo forum they also talk about calcium

dysfunction. I have no idea if they are talking about the same thing though. The

vit k people talk about the body being unable to

process calcium and storing it in the soft tissue where it is toxic (I think,

please correct me more scientific people). If you read their papers, vitamin k2

will help with this badly stored calcium, again better for you to read their

explanation than for me to try to repeat it.

In

Tom’s case, we just tried GABA after starting to read Yasko’s book

and it made a big difference to his language. We gave him a very big dose by

mistake which I should be ashamed of but we saw a very big difference.

Although

Tom was improving on biomed, there was something

about him that was getting worse. I would look back at old videos and see that

he was gaining language and skills but he had lost some cheerfulness and

playfulness. Calcium was one of the first supplements we had put him on and we

did a test of removing it and putting it back in a couple of times, 2 week on,

2 weeks off, 2 weeks on 2 weeks off. We saw that he was happier and more

playful without it and, even more obviously, I saw that the calcium was causing

jerky movements in his arms – the kind of involuntary movements babies

make. I realised then that they had been there before and at the time of

diagnosis and had all but disappeared when we took him off milk. They had

probably returned when we started him on calcium. He doesn’t have them

now.

Hope that helps. I would never think you were pestering.

SARA

-----Original

Message-----

From: Autism-Biomedical-Europe [mailto:Autism-Biomedical-Europe ] On Behalf Of

Scorer

Sent: 28

September 2007

13:25

To: Autism-Biomedical-Europe

Subject:

Re: High glutamate and neuronal death

Hi Sara,

Me again pestering! What was the reason you used GABA and why do you

think stopping calcium helped? Sorry this is not coming out right

(tryin to figure out what I'm asking), how does the calcium fit into all

of this?

emily

> > > > >

> > > > > Hi Peta,

> > > > >

> > > > > Amy Yasko is really keen about reducing glutamates and

> > > supplementing

> > > > > a small amount of Gaba.

> > > > >

> > > > > As well as avoiding overly glutamate foods this also

means

> NOT

> > > > > supplementing L-gluatime or using alpha keto

glutarates etc.

> I

> > > > > can't find a good summary on-line - I'll paste what I

could

> find

> > > > > below. We were supplementing l-glutamine a lot before

and

> were

> > > slow

> > > > > to reduce and then remove it - but Eddie's

glutamine/gaba

> have

> > > > > actually balanced out. So while we were supplementing

he was

> low

> > > and

> > > > > when we stopped he improved. The more I learn the more

I like

> > > Yasko -

> > > > > it is doing great things for Eddie.

> > > > >

> > > > > Best wishes,

> > > > > Sandy

> > > > >

> > > > > http://forums. <http://forums. about.com/ n/pfx/forum. aspx?

> > > <http://forums. <http://forums.about.com/n/pfx/forum.aspx?>

> about.com/n/pfx/forum.aspx?>>

> > > > about.com/n/ pfx/forum. aspx?

> > > > > nav=printDiscussion & webtag=ab- autism & tid=

4426

> > > > > COPIED from this link ....

> > > > > FYI, Here is some of what Dr Amy Yasko says about

glutamate

> > > in " The

> > > > > Puzzle of Autism: Putting it all Together " : (pgs

8-9)

> > > > >

> > > > > " Glutamate is the main excitatory

neurotransmitter in the

> body.

> > > It is

> > > > > essential for learning and for both short-term and

long-term

> > > memory.

> > > > > It is also the precursor to the inhibitory

neurotransmitter,

> GABA.

> > > > > GABA is a calming neurotransmitter and is essential

for

> speech.

> > > GABA

> > > > > neurons damp the propagation of sounds so that a

distinction

> can

> > > be

> > > > > made between the onset of a sound and background

> noise....Problems

> > > > > occur if the normal process of regulation of glutamate

> > > malfunctions

> > > > > and if toxic levels of this excitatory

neurotransmitter

> build up

> > > in

> > > > > the synaptic junctions.

> > > > > The balance between glutamate and GABA is like a

seesaw.

> Under

> > > normal

> > > > > conditions, when the glutamate side gets too high, the

GABA

> side

> > > of

> > > > > the seesaw will increase and decrease the glutamate.

Under

> normal

> > > > > functioning conditions, excess levels of the

excitotoxin

> glutamate

> > > > > will convert to GABA. There seems to be a

" disconnect " in

> this

> > > > > process for autistic children so that the excitatory

> > > > > neurotransmission is high (stims) and the calming

> > > neurotransmission

> > > > > is low (lack of speech). When conditions occur that

throw

> off this

> > > > > delicate balance, then high levels of glutamate can

> accumulate

> > > while

> > > > > the levels of GABA remain exceedingly low. This would

create

> a

> > > > > situation that would require decreasing the glutamate

> levels, and

> > > > > increasing the GABA levels in order to restore

balance.

> Chronic

> > > viral

> > > > > infection may be related to this disconnect between

> glutamate and

> > > > > GABA. "

> > > > >

> > > > > " Over seven years ago, Dr Blaylock

described the

> pathway

> > > of

> > > > > excitotoxin damage and the role it plays in

neurological

> damage

> > > > > brilliantly in his landmark book on excitotoxins. He

spelled

> out

> > > > > specifically how and why MSG, hydrolyzed vegetable

protein,

> > > aspartame

> > > > > and related compounds have been proven to cause death

of

> neurons

> > > > > beyond any reasonable doubt. More recently, this

concept of

> > > > > excitotoxin damage has been found to pertain to

autism.

> > > Excitotoxins

> > > > > are neurotransmitters such as glutamate or aspartate

> > > > > that can excite the nerves to death when their levels

are not

> > > > > regulated properly. Foods or supplements that contain

> excitotoxins

> > > > > include MSG, glutamic acid, glutamine, Nutra Sweet,

> aspartate,

> > > > > aspartame and cysteine. Mercury and aluminum can

trigger

> glutamate

> > > > > release. Minimizing glutatmate is a differentiating

factor

> in our

> > > > > protocol and has helped many autistic children

> significantly. "

> > > > >

> > > >

> > >

> > > ----------------------------------------------------------

> -------

> > >

> > > No virus found in this incoming message.

> > > Checked by AVG Free Edition.

> > > Version: 7.5.488 / Virus Database: 269.13.30/1030 - Release

> Date: 25/09/2007 08:02

> > >

> >

>

September 28, 2007

Which vitamin D do you use, Mandi .. We are currently doing only the arctic CLO from NN, but Im am not sure there is enough vitamin D in it ??

>>>We have the SNP that means we have to go lightly on the lipids so we use dry D3 Twinlabs combo Allergy A (10,000ius) & D (400iu's) and the HHC D3 which is tabs and 1,000iu's, he gets a Kirkman CLO once or twice per week also.

The Vitamin K list recommend Green Pastures CLO thats much higher A & D than the others and with Butter oil for the Vitamin K2 also but its scarey expensive and won't let you order it from outside the US.

Mandi x

September 28, 2007

Katy is not very verbal,can tell you what she wants,no conversation,and understands most speech.Maybe the make didn't agree with her ,it is Source naturals.I'm glad Tom had such good results from taking it.I'll probably try it again in the future.

>>>Sharion Sam didn't seem to do well on it the first time out but we are doing it again now for 3 weeks and he is doing well.

I have been revisiting my supplement museum and thats happening with a few other things as well, spooky, maybe since we have the Folapro in now he cna handle things he had a hard time with before - who knows, at the moment I am scared to rock the boat just in case LOL

Mandi x

September 28, 2007

Hi Sara

Does that mean if your child has high glutamate levels then you

shouldn't supplement calcium?

Peta-

-- In Autism-Biomedical-Europe , " Sass and Rem "

wrote:

>

> Hello ,

> I'm probably the worst person in the world to explain this with my

very

> unscientific brain so I'll copy a bit of Yasko's book again…

> " Glutamate has six different types of receptors to which it can

bind in

> the brain. One of these receptors, the NMDA receptor, is tied to

calcium

> transport as its mode of action. In the case of the NMDA receptors,

the

> release of excess glutamate triggers an inflammatory cascade that

> results in the death of neurons by the major influx of calcium into

the

> nerve until it results in neural cell death. Normal levels of

calcium

> result in normal neuron functioning. However, excessive levels of

> calcium make it impossible for the neuron to rest; the neuron

continues

> to fire without stopping causing the release of inflammatory

mediators,

> the release of more glutamate, thus resulting in more calcium

influx.

> The high intracellular levels of calcium also lead to high levels of

> nitric oxide and peroxynitrite, causing damage to the energy

producing

> apparatus of the cells. Magnesium (a second part of Dr. Rimland's

> protocol) is able to modulate the calcium flow, as is zinc. However

zinc

> is a double-edged sword as it is also able to activate glutamate

release

> via the non-NMDA glutamate receptors. "

> On the Vit k yahoo forum they also talk about calcium dysfunction. I

> have no idea if they are talking about the same thing though. The

vit k

> people talk about the body being unable to process calcium and

storing

> it in the soft tissue where it is toxic (I think, please correct me

more

> scientific people). If you read their papers, vitamin k2 will help

with

> this badly stored calcium, again better for you to read their

> explanation than for me to try to repeat it.

>

> In Tom's case, we just tried GABA after starting to read Yasko's

book

> and it made a big difference to his language. We gave him a very big

> dose by mistake which I should be ashamed of but we saw a very big

> difference.

> Although Tom was improving on biomed, there was something about him

that

> was getting worse. I would look back at old videos and see that he

was

> gaining language and skills but he had lost some cheerfulness and

> playfulness. Calcium was one of the first supplements we had put

him on

> and we did a test of removing it and putting it back in a couple of

> times, 2 week on, 2 weeks off, 2 weeks on 2 weeks off. We saw that

he

> was happier and more playful without it and, even more obviously, I

saw

> that the calcium was causing jerky movements in his arms – the kind

of

> involuntary movements babies make. I realised then that they had

been

> there before and at the time of diagnosis and had all but

disappeared

> when we took him off milk. They had probably returned when we

started

> him on calcium. He doesn't have them now.

> Hope that helps. I would never think you were pestering.

> SARA

>

> Re: High glutamate and neuronal

> death

>

> Hi Sara,

>

> Me again pestering! What was the reason you used GABA and why do you

> think stopping calcium helped? Sorry this is not coming out right

> (tryin to figure out what I'm asking), how does the calcium fit

into all

> of this?

>

> emily

>

> > > > > >

> > > > > > Hi Peta,

> > > > > >

> > > > > > Amy Yasko is really keen about reducing glutamates and

> > > > supplementing

> > > > > > a small amount of Gaba.

> > > > > >

> > > > > > As well as avoiding overly glutamate foods this also means

> > NOT

> > > > > > supplementing L-gluatime or using alpha keto glutarates

etc.

> > I

> > > > > > can't find a good summary on-line - I'll paste what I

could

> > find

> > > > > > below. We were supplementing l-glutamine a lot before and

> > were

> > > > slow

> > > > > > to reduce and then remove it - but Eddie's glutamine/gaba

> > have

> > > > > > actually balanced out. So while we were supplementing he

was

> > low

> > > > and

> > > > > > when we stopped he improved. The more I learn the more I

like

> > > > Yasko -

> > > > > > it is doing great things for Eddie.

> > > > > >

> > > > > > Best wishes,

> > > > > > Sandy

> > > > > >

> > > > > > http://forums. <http://forums. about.com/ n/pfx/forum.

aspx?

> > > > <http://forums. <http://forums.

> <http://forums.about.com/n/pfx/forum.aspx?>

about.com/n/pfx/forum.aspx?>

> > about.com/n/pfx/forum.aspx?>>

> > > > > about.com/n/ pfx/forum. aspx?

> > > > > > nav=printDiscussion & webtag=ab- autism & tid= 4426

> > > > > > COPIED from this link ....

> > > > > > FYI, Here is some of what Dr Amy Yasko says about

glutamate

> > > > in " The

> > > > > > Puzzle of Autism: Putting it all Together " : (pgs 8-9)

> > > > > >

> > > > > > " Glutamate is the main excitatory neurotransmitter in the

> > body.

> > > > It is

> > > > > > essential for learning and for both short-term and long-

term

> > > > memory.

> > > > > > It is also the precursor to the inhibitory

neurotransmitter,

> > GABA.

> > > > > > GABA is a calming neurotransmitter and is essential for

> > speech.

> > > > GABA

> > > > > > neurons damp the propagation of sounds so that a

distinction

> > can

> > > > be

> > > > > > made between the onset of a sound and background

> > noise....Problems

> > > > > > occur if the normal process of regulation of glutamate

> > > > malfunctions

> > > > > > and if toxic levels of this excitatory neurotransmitter

> > build up

> > > > in

> > > > > > the synaptic junctions.

> > > > > > The balance between glutamate and GABA is like a seesaw.

> > Under

> > > > normal

> > > > > > conditions, when the glutamate side gets too high, the

GABA

> > side

> > > > of

> > > > > > the seesaw will increase and decrease the glutamate. Under

> > normal

> > > > > > functioning conditions, excess levels of the excitotoxin

> > glutamate

> > > > > > will convert to GABA. There seems to be a " disconnect " in

> > this

> > > > > > process for autistic children so that the excitatory

> > > > > > neurotransmission is high (stims) and the calming

> > > > neurotransmission

> > > > > > is low (lack of speech). When conditions occur that throw

> > off this

> > > > > > delicate balance, then high levels of glutamate can

> > accumulate

> > > > while

> > > > > > the levels of GABA remain exceedingly low. This would

create

> > a

> > > > > > situation that would require decreasing the glutamate

> > levels, and

> > > > > > increasing the GABA levels in order to restore balance.

> > Chronic

> > > > viral

> > > > > > infection may be related to this disconnect between

> > glutamate and

> > > > > > GABA. "

> > > > > >

> > > > > > " Over seven years ago, Dr Blaylock described the

> > pathway

> > > > of

> > > > > > excitotoxin damage and the role it plays in neurological

> > damage

> > > > > > brilliantly in his landmark book on excitotoxins. He

spelled

> > out

> > > > > > specifically how and why MSG, hydrolyzed vegetable

protein,

> > > > aspartame

> > > > > > and related compounds have been proven to cause death of

> > neurons

> > > > > > beyond any reasonable doubt. More recently, this concept

of

> > > > > > excitotoxin damage has been found to pertain to autism.

> > > > Excitotoxins

> > > > > > are neurotransmitters such as glutamate or aspartate

> > > > > > that can excite the nerves to death when their levels are

not

> > > > > > regulated properly. Foods or supplements that contain

> > excitotoxins

> > > > > > include MSG, glutamic acid, glutamine, Nutra Sweet,

> > aspartate,

> > > > > > aspartame and cysteine. Mercury and aluminum can trigger

> > glutamate

> > > > > > release. Minimizing glutatmate is a differentiating factor

> > in our

> > > > > > protocol and has helped many autistic children

> > significantly. "

> > > > > >

> > > > >

> > > >

> > > > ----------------------------------------------------------

> > -------

> > > >

> > > > No virus found in this incoming message.

> > > > Checked by AVG Free Edition.

> > > > Version: 7.5.488 / Virus Database: 269.13.30/1030 - Release

> > Date: 25/09/2007 08:02

> > > >

> > >

> >

>

September 28, 2007

-Vicky and listmates,

What dosage of L.Glutamine did you give ?I have started Katy on

this over the last 2 weeks ,we are now up to 2 gms divided

throughout the day.We haven't seen anything bad as yet,in fact seems

to have a bit more energy and does not look so sallow ,also has more

focus.Our homeopath recommended it as Katy was constantly looking

for food.

After taking Gaba ,Katy seems to get a bloated tummy and does not

focus so well,not as keen on talking.Wondered if anyone else had

this reaction.

Sharon .

-- In Autism-Biomedical-Europe , MaddiganV@... wrote:

>

> L Glutamine was one of the better supplements we used with .

> It was reccomended to me here yonks ago and alongside enzymes

really

> contributed to his gut healing, he did fantastically well for yrs,

didn't use it

> as an all the time thing but certainly helped in settling things

down at the

> start.

> Didn't see any behaviours from using it, if anything his

behaviour

> imporved considerably from being free of pain.

> For behaviours almost always come with a gut problem.

> There doesn't seem to be a hard and fast rule with much of this,

or

> certainly not with my kid, since re-introducing Vit D his bowels

are slowly getting

> better, Why?

> I'm hoping to figure this all out before he is collecting his

pension. I'm

> not keen on any Dr or nutritionist saying something is an

absolute, in as much

> as must do a certain diet or won't use a certain supplement across

the board

> for every child. Just my very non scientific observations.

> Vicky

>

September 28, 2007

Not

a clue, sorry Peta. I know so little. I didn’t

even know you could test for high glutamate levels! All I can say as a mum is,

if you recognise those jerky movements that Tom had in your own child, then

read up on the Vit k group stuff and give your child

a trial on and off calcium perhaps???

Sara

-----Original

Message-----

From:

Autism-Biomedical-Europe

[mailto:Autism-Biomedical-Europe ] On Behalf Of peta3366

Sent: 28 September 2007 16:49

To:

Autism-Biomedical-Europe

Subject:

Re: High glutamate and neuronal death

Hi Sara

Does that mean if your child has high glutamate levels then you

shouldn't supplement calcium?

Peta-

-- In Autism-Biomedical-Europe ,

" Sass and Rem "

wrote:

>

> Hello ,

> I'm probably the worst person in the world to explain this with my

very

> unscientific brain so I'll copy a bit of Yasko's book again…

> " Glutamate has six different types of receptors to which it can

bind in

> the brain. One of these receptors, the NMDA receptor, is tied to

calcium

> transport as its mode of action. In the case of the NMDA receptors,

the

> release of excess glutamate triggers an inflammatory cascade that

> results in the death of neurons by the major influx of calcium into

the

> nerve until it results in neural cell death. Normal levels of

calcium

> result in normal neuron functioning. However, excessive levels of

> calcium make it impossible for the neuron to rest; the neuron

continues

> to fire without stopping causing the release of inflammatory

mediators,

> the release of more glutamate, thus resulting in more calcium

influx.

> The high intracellular levels of calcium also lead to high levels of

> nitric oxide and peroxynitrite, causing damage to the energy

producing

> apparatus of the cells. Magnesium (a second part of Dr. Rimland's

> protocol) is able to modulate the calcium flow, as is zinc. However

zinc

> is a double-edged sword as it is also able to activate glutamate

release

> via the non-NMDA glutamate receptors. "

> On the Vit k yahoo forum they also talk about calcium dysfunction. I

> have no idea if they are talking about the same thing though. The

vit k

> people talk about the body being unable to process calcium and

storing

> it in the soft tissue where it is toxic (I think, please correct me

more

> scientific people). If you read their papers, vitamin k2 will help

with

> this badly stored calcium, again better for you to read their

> explanation than for me to try to repeat it.

>

> In Tom's case, we just tried GABA after starting to read Yasko's

book

> and it made a big difference to his language. We gave him a very big

> dose by mistake which I should be ashamed of but we saw a very big

> difference.

> Although Tom was improving on biomed, there was something about him

that

> was getting worse. I would look back at old videos and see that he

was

> gaining language and skills but he had lost some cheerfulness and

> playfulness. Calcium was one of the first supplements we had put

him on

> and we did a test of removing it and putting it back in a couple of

> times, 2 week on, 2 weeks off, 2 weeks on 2 weeks off. We saw that

he

> was happier and more playful without it and, even more obviously, I

saw

> that the calcium was causing jerky movements in his arms – the kind

of

> involuntary movements babies make. I realised then that they had

been

> there before and at the time of diagnosis and had all but

disappeared

> when we took him off milk. They had probably returned when we

started

> him on calcium. He doesn't have them now.

> Hope that helps. I would never think you were pestering.

> SARA

>

> Re: High glutamate and neuronal

> death

>

> Hi Sara,

>

> Me again pestering! What was the reason you used GABA and why do you

> think stopping calcium helped? Sorry this is not coming out right

> (tryin to figure out what I'm asking), how does the calcium fit

into all

> of this?

>

> emily

>

> > > > > >

> > > > > > Hi Peta,

> > > > > >

> > > > > > Amy Yasko is really keen about reducing

glutamates and

> > > > supplementing

> > > > > > a small amount of Gaba.

> > > > > >

> > > > > > As well as avoiding overly glutamate foods this

also means

> > NOT

> > > > > > supplementing L-gluatime or using alpha keto

glutarates

etc.

> > I

> > > > > > can't find a good summary on-line - I'll paste what

I

could

> > find

> > > > > > below. We were supplementing l-glutamine a lot

before and

> > were

> > > > slow

> > > > > > to reduce and then remove it - but Eddie's

glutamine/gaba

> > have

> > > > > > actually balanced out. So while we were

supplementing he

was

> > low

> > > > and

> > > > > > when we stopped he improved. The more I learn the

more I

like

> > > > Yasko -

> > > > > > it is doing great things for Eddie.

> > > > > >

> > > > > > Best wishes,

> > > > > > Sandy

> > > > > >

> > > > > > http://forums. <http://forums. about.com/ n/pfx/forum.

aspx?

> > > > <http://forums. <http://forums.

> <http://forums.about.com/n/pfx/forum.aspx?>

about.com/n/pfx/forum.aspx?>

> > about.com/n/pfx/forum.aspx?>>

> > > > > about.com/n/ pfx/forum. aspx?

> > > > > > nav=printDiscussion & webtag=ab-

autism & tid= 4426

> > > > > > COPIED from this link ....

> > > > > > FYI, Here is some of what Dr Amy Yasko says about

glutamate

> > > > in " The

> > > > > > Puzzle of Autism: Putting it all Together " :

(pgs 8-9)

> > > > > >

> > > > > > " Glutamate is the main excitatory

neurotransmitter in the

> > body.

> > > > It is

> > > > > > essential for learning and for both short-term

and long-

term

> > > > memory.

> > > > > > It is also the precursor to the inhibitory

neurotransmitter,

> > GABA.

> > > > > > GABA is a calming neurotransmitter and is

essential for

> > speech.

> > > > GABA

> > > > > > neurons damp the propagation of sounds so that a

distinction

> > can

> > > > be

> > > > > > made between the onset of a sound and background

> > noise....Problems

> > > > > > occur if the normal process of regulation of

glutamate

> > > > malfunctions

> > > > > > and if toxic levels of this excitatory

neurotransmitter

> > build up

> > > > in

> > > > > > the synaptic junctions.

> > > > > > The balance between glutamate and GABA is like a

seesaw.

> > Under

> > > > normal

> > > > > > conditions, when the glutamate side gets too

high, the

GABA

> > side

> > > > of

> > > > > > the seesaw will increase and decrease the

glutamate. Under

> > normal

> > > > > > functioning conditions, excess levels of the

excitotoxin

> > glutamate

> > > > > > will convert to GABA. There seems to be a

" disconnect " in

> > this

> > > > > > process for autistic children so that the

excitatory

> > > > > > neurotransmission is high (stims) and the calming

> > > > neurotransmission

> > > > > > is low (lack of speech). When conditions occur

that throw

> > off this

> > > > > > delicate balance, then high levels of glutamate

can

> > accumulate

> > > > while

> > > > > > the levels of GABA remain exceedingly low. This

would

create

> > a

> > > > > > situation that would require decreasing the

glutamate

> > levels, and

> > > > > > increasing the GABA levels in order to restore

balance.

> > Chronic

> > > > viral

> > > > > > infection may be related to this disconnect

between

> > glutamate and

> > > > > > GABA. "

> > > > > >

> > > > > > " Over seven years ago, Dr Blaylock

described the

> > pathway

> > > > of

> > > > > > excitotoxin damage and the role it plays in

neurological

> > damage

> > > > > > brilliantly in his landmark book on excitotoxins.

He

spelled

> > out

> > > > > > specifically how and why MSG, hydrolyzed

vegetable

protein,

> > > > aspartame

> > > > > > and related compounds have been proven to cause

death of

> > neurons

> > > > > > beyond any reasonable doubt. More recently, this

concept

of

> > > > > > excitotoxin damage has been found to pertain to

autism.

> > > > Excitotoxins

> > > > > > are neurotransmitters such as glutamate or

aspartate

> > > > > > that can excite the nerves to death when their

levels are

not

> > > > > > regulated properly. Foods or supplements that

contain

> > excitotoxins

> > > > > > include MSG, glutamic acid, glutamine, Nutra

Sweet,

> > aspartate,

> > > > > > aspartame and cysteine. Mercury and aluminum can

trigger

> > glutamate

> > > > > > release. Minimizing glutatmate is a

differentiating factor

> > in our

> > > > > > protocol and has helped many autistic children

> > significantly. "

> > > > > >

> > > > >

> > > >

> > > > ----------------------------------------------------------

> > -------

> > > >

> > > > No virus found in this incoming message.

> > > > Checked by AVG Free Edition.

> > > > Version: 7.5.488 / Virus Database: 269.13.30/1030 - Release

> > Date: 25/09/2007 08:02

> > > >

> > >

> >

>

September 28, 2007

Don’t

know Sharon but a while back I posted about our great

success with GABA and I remember other mums reporting negative reactions. Can’t

remember what they were now. Amazingly different reactions

though from Katy and Tom. Is Katy very verbal? I have heard that GABA is

used to restore speech in stroke victims. It really helped with Tom’s

speech. Sara

-----Original

Message-----

From: Autism-Biomedical-Europe

[mailto:Autism-Biomedical-Europe ] On Behalf Of Sharon

Sent: 28 September 2007 16:52

To:

Autism-Biomedical-Europe

Subject:

Re: High glutamate and neuronal death

-Vicky and listmates,

What dosage of L.Glutamine did you give ?I have started Katy on

this over the last 2 weeks ,we are now up to 2 gms divided

throughout the day.We haven't seen anything bad as yet,in fact seems

to have a bit more energy and does not look so sallow ,also has more

focus.Our homeopath recommended it as Katy was constantly looking

for food.

After taking Gaba ,Katy seems to get a bloated tummy and does not

focus so well,not as keen on talking.Wondered if anyone else had

this reaction.

Sharon .

-- In Autism-Biomedical-Europe ,

MaddiganV@... wrote:

>

> L Glutamine was one of the better supplements we used with .

> It was reccomended to me here yonks ago and alongside enzymes

really

> contributed to his gut healing, he did fantastically well for yrs,

didn't use it

> as an all the time thing but certainly helped in settling things

down at the

> start.

> Didn't see any behaviours from using it, if anything his

behaviour

> imporved considerably from being free of pain.

> For behaviours almost always come with a gut problem.

> There doesn't seem to be a hard and fast rule with much of this,

or

> certainly not with my kid, since re-introducing Vit D his bowels

are slowly getting

> better, Why?

> I'm hoping to figure this all out before he is collecting his

pension. I'm

> not keen on any Dr or nutritionist saying something is an

absolute, in as much

> as must do a certain diet or won't use a certain supplement across

the board

> for every child. Just my very non scientific observations.

> Vicky

>

September 28, 2007

How is Folapro indicated as being needed?

>>For us it was via Yasko Genomics testing - anybody that wants to take a look at Sam's GAR is welcome, its a big 89 page PDF file

Mandi x

September 28, 2007

Which vitamin D do you use, Mandi .. We are currently doing only the arctic CLO from NN, but Im am not sure there is enough vitamin D in it ??

Ulla, Denmark

Re: Re: High glutamate and neuronal death

In a message dated 28/09/2007 14:29:24 GMT Standard Time, MaddiganVaol writes:

L Glutamine was one of the better supplements we used with .

It was reccomended to me here yonks ago and alongside enzymes really contributed to his gut healing, he did fantastically well for yrs, didn't use it as an all the time thing but certainly helped in settling things down at the start.

Didn't see any behaviours from using it, if anything his behaviour imporved considerably from being free of pain.

>>We also used L-Glutamine years ago with Sam, can't say I saw anything good or bad in partticular because nothiing much was working before HNI - BUT when we first started on them, HNI contained Peptizyde contained L-Glutamine! It was removed after about 6 months because some were seeing hyperactivity and the L-Glutamine was considered the culprit by parents.

For behaviours almost always come with a gut problem.

There doesn't seem to be a hard and fast rule with much of this, or certainly not with my kid, since re-introducing Vit D his bowels are slowly getting better, Why

>>>because Vitamin D does all sorts of wonderful things, helping against virus is one and helping calciu transport is another - both of which I think has issues with . There is a great site about it all I think this is the one

http://www.vitamindcouncil.com/

Mandi x

September 28, 2007

Hi Sara,

Katy is not very verbal,can tell you what she wants,no

conversation,and understands most speech.

Maybe the make didn't agree with her ,it is Source naturals.

I'm glad Tom had such good results from taking it.I'll probably try

it again in the future.

Sharon.

> >

> > L Glutamine was one of the better supplements we used with .

> > It was reccomended to me here yonks ago and alongside enzymes

> really

> > contributed to his gut healing, he did fantastically well for

yrs,

> didn't use it

> > as an all the time thing but certainly helped in settling things

> down at the

> > start.

> > Didn't see any behaviours from using it, if anything his

> behaviour

> > imporved considerably from being free of pain.

> > For behaviours almost always come with a gut problem.

> > There doesn't seem to be a hard and fast rule with much of this,

> or

> > certainly not with my kid, since re-introducing Vit D his bowels

> are slowly getting

> > better, Why?

> > I'm hoping to figure this all out before he is collecting his

> pension. I'm

> > not keen on any Dr or nutritionist saying something is an

> absolute, in as much

> > as must do a certain diet or won't use a certain supplement

across

> the board

> > for every child. Just my very non scientific observations.

> > Vicky

> >

>

September 28, 2007

Thanks Sara

We did a urine test through neuro science in the States.

Peta--

- In Autism-Biomedical-Europe , " Sass and Rem " <Moroza-

@...> wrote:

>

> Not a clue, sorry Peta. I know so little. I didn't even know you

could

> test for high glutamate levels! All I can say as a mum is, if you

> recognise those jerky movements that Tom had in your own child, then

> read up on the Vit k group stuff and give your child a trial on and

off

> calcium perhaps???

> Sara

>

> Re: High glutamate and

neuronal

> > death

> >

> > Hi Sara,

> >

> > Me again pestering! What was the reason you used GABA and why do

you

> > think stopping calcium helped? Sorry this is not coming out right

> > (tryin to figure out what I'm asking), how does the calcium fit

> into all

> > of this?

> >

> > emily

> >

> > > > > > >

> > > > > > > Hi Peta,

> > > > > > >

> > > > > > > Amy Yasko is really keen about reducing glutamates and

> > > > > supplementing

> > > > > > > a small amount of Gaba.

> > > > > > >

> > > > > > > As well as avoiding overly glutamate foods this also

means

> > > NOT

> > > > > > > supplementing L-gluatime or using alpha keto glutarates

> etc.

> > > I

> > > > > > > can't find a good summary on-line - I'll paste what I

> could

> > > find

> > > > > > > below. We were supplementing l-glutamine a lot before

and

> > > were

> > > > > slow

> > > > > > > to reduce and then remove it - but Eddie's

glutamine/gaba

> > > have

> > > > > > > actually balanced out. So while we were supplementing

he

> was

> > > low

> > > > > and

> > > > > > > when we stopped he improved. The more I learn the more

I

> like

> > > > > Yasko -

> > > > > > > it is doing great things for Eddie.

> > > > > > >

> > > > > > > Best wishes,

> > > > > > > Sandy

> > > > > > >

> > > > > > > http://forums. <http://forums. about.com/ n/pfx/forum.

> aspx?

> > > > > <http://forums. <http://forums.

> > <http://forums. <http://forums.about.com/n/pfx/forum.aspx?>

> about.com/n/pfx/forum.aspx?>

> > > about.com/n/pfx/forum.aspx?>>

> > > > > > about.com/n/ pfx/forum. aspx?

> > > > > > > nav=printDiscussion & webtag=ab- autism & tid= 4426

> > > > > > > COPIED from this link ....

> > > > > > > FYI, Here is some of what Dr Amy Yasko says about

> glutamate

> > > > > in " The

> > > > > > > Puzzle of Autism: Putting it all Together " : (pgs 8-9)

> > > > > > >

> > > > > > > " Glutamate is the main excitatory neurotransmitter in

the

> > > body.

> > > > > It is

> > > > > > > essential for learning and for both short-term and long-

> term

> > > > > memory.

> > > > > > > It is also the precursor to the inhibitory

> neurotransmitter,

> > > GABA.

> > > > > > > GABA is a calming neurotransmitter and is essential for

> > > speech.

> > > > > GABA

> > > > > > > neurons damp the propagation of sounds so that a

> distinction

> > > can

> > > > > be

> > > > > > > made between the onset of a sound and background

> > > noise....Problems

> > > > > > > occur if the normal process of regulation of glutamate

> > > > > malfunctions

> > > > > > > and if toxic levels of this excitatory neurotransmitter

> > > build up

> > > > > in

> > > > > > > the synaptic junctions.

> > > > > > > The balance between glutamate and GABA is like a seesaw.

> > > Under

> > > > > normal

> > > > > > > conditions, when the glutamate side gets too high, the

> GABA

> > > side

> > > > > of

> > > > > > > the seesaw will increase and decrease the glutamate.

Under

> > > normal

> > > > > > > functioning conditions, excess levels of the excitotoxin

> > > glutamate

> > > > > > > will convert to GABA. There seems to be a " disconnect "

in

> > > this

> > > > > > > process for autistic children so that the excitatory

> > > > > > > neurotransmission is high (stims) and the calming

> > > > > neurotransmission

> > > > > > > is low (lack of speech). When conditions occur that

throw

> > > off this

> > > > > > > delicate balance, then high levels of glutamate can

> > > accumulate

> > > > > while

> > > > > > > the levels of GABA remain exceedingly low. This would

> create

> > > a

> > > > > > > situation that would require decreasing the glutamate

> > > levels, and

> > > > > > > increasing the GABA levels in order to restore balance.

> > > Chronic

> > > > > viral

> > > > > > > infection may be related to this disconnect between

> > > glutamate and

> > > > > > > GABA. "

> > > > > > >

> > > > > > > " Over seven years ago, Dr Blaylock described the

> > > pathway

> > > > > of

> > > > > > > excitotoxin damage and the role it plays in neurological

> > > damage

> > > > > > > brilliantly in his landmark book on excitotoxins. He

> spelled

> > > out

> > > > > > > specifically how and why MSG, hydrolyzed vegetable

> protein,

> > > > > aspartame

> > > > > > > and related compounds have been proven to cause death of

> > > neurons

> > > > > > > beyond any reasonable doubt. More recently, this

concept

> of

> > > > > > > excitotoxin damage has been found to pertain to autism.

> > > > > Excitotoxins

> > > > > > > are neurotransmitters such as glutamate or aspartate

> > > > > > > that can excite the nerves to death when their levels

are

> not

> > > > > > > regulated properly. Foods or supplements that contain

> > > excitotoxins

> > > > > > > include MSG, glutamic acid, glutamine, Nutra Sweet,

> > > aspartate,

> > > > > > > aspartame and cysteine. Mercury and aluminum can trigger

> > > glutamate

> > > > > > > release. Minimizing glutatmate is a differentiating

factor

> > > in our

> > > > > > > protocol and has helped many autistic children

> > > significantly. "

> > > > > > >

> > > > > >

> > > > >

> > > > > ----------------------------------------------------------

> > > -------

> > > > >

> > > > > No virus found in this incoming message.

> > > > > Checked by AVG Free Edition.

> > > > > Version: 7.5.488 / Virus Database: 269.13.30/1030 - Release

> > > Date: 25/09/2007 08:02

> > > > >

> > > >

> > >

> >

>

September 28, 2007

How is Folapro indicated as being needed?

sheesh, i can't keep up with all these supplements.

anyone let me know, much appreciated.

>

> In a message dated 28/09/2007 19:26:39 GMT Standard Time,

> bill.molineux@... writes:

>

> Katy is not very verbal,can tell you what she wants,no

> conversation,conversation,<WBR>and unders

> Maybe the make didn't agree with her ,it is Source naturals.

>

> I'm glad Tom had such good results from taking it.I'll probably

try

> it again in the future.

>

> >>>Sharion Sam didn't seem to do well on it the first time out

but we are

> doing it again now for 3 weeks and he is doing well.

>

> I have been revisiting my supplement museum and thats happening

with a few

> other things as well, spooky, maybe since we have the Folapro in

now he cna

> handle things he had a hard time with before - who knows, at the

moment I am

> scared to rock the boat just in case LOL

>

> Mandi x

>

September 28, 2007

Hi Mandi,

Great that Sam is doing so well on Yasko !I looked into this ,we did

her SNP's but I was struggling with getting her to tolerate the

basic Step one supplements so I left it alone.

We have stuck with LOD for two years and she is now tolerating some

more supplements she could not handle before Mag citrate and also

small amounts of B.complex vits ,Epsom Salts baths ,also sulphur

foods such as cabbage and brocolli,also taking other stuff. We are

also doing sequential homeopathy and she is receiving lots of

support through this.

I'll likely try the gaba again as I have such a big tub of it !

Think I'm going to get me and Bill taking the stuff she can't

handle ,maybe next year we'll both do the full marathon ! LOL!!

Sharon.

..

>

> In a message dated 28/09/2007 19:26:39 GMT Standard Time,

> bill.molineux@... writes:

>

> Katy is not very verbal,can tell you what she wants,no

> conversation,conversation,<WBR>and unders

> Maybe the make didn't agree with her ,it is Source naturals.

>

> I'm glad Tom had such good results from taking it.I'll probably

try

> it again in the future.

>

> >>>Sharion Sam didn't seem to do well on it the first time out

but we are

> doing it again now for 3 weeks and he is doing well.

>

> I have been revisiting my supplement museum and thats happening

with a few

> other things as well, spooky, maybe since we have the Folapro in

now he cna

> handle things he had a hard time with before - who knows, at the

moment I am

> scared to rock the boat just in case LOL

>

> Mandi x

>

September 29, 2007

Hi Sara,

Thank you so much for sharing all of this, and copying Yasko's

explanation, you're a star!

From what you've said, am I correct that you are still not giving Tom

any calcium and that he is is also casein free? How else does he get

the calcium his body might need for bones, teeth etc.?

I think that doing a trial of on and off calcium may be something to

consider here and I will also go back and look at the vit K forum.

emily xx

> > > > > >

> > > > > > Hi Peta,

> > > > > >

> > > > > > Amy Yasko is really keen about reducing glutamates and

> > > > supplementing

> > > > > > a small amount of Gaba.

> > > > > >

> > > > > > As well as avoiding overly glutamate foods this also means

> > NOT

> > > > > > supplementing L-gluatime or using alpha keto glutarates etc.

> > I

> > > > > > can't find a good summary on-line - I'll paste what I could

> > find

> > > > > > below. We were supplementing l-glutamine a lot before and

> > were

> > > > slow

> > > > > > to reduce and then remove it - but Eddie's glutamine/gaba

> > have

> > > > > > actually balanced out. So while we were supplementing he was

> > low

> > > > and

> > > > > > when we stopped he improved. The more I learn the more I

like

> > > > Yasko -

> > > > > > it is doing great things for Eddie.

> > > > > >

> > > > > > Best wishes,

> > > > > > Sandy

> > > > > >

> > > > > > http://forums. <http://forums. about.com/ n/pfx/forum. aspx?

> > > > <http://forums. <http://forums.

> <http://forums.about.com/n/pfx/forum.aspx?>

about.com/n/pfx/forum.aspx?>

> > about.com/n/pfx/forum.aspx?>>

> > > > > about.com/n/ pfx/forum. aspx?

> > > > > > nav=printDiscussion & webtag=ab- autism & tid= 4426

> > > > > > COPIED from this link ....

> > > > > > FYI, Here is some of what Dr Amy Yasko says about glutamate

> > > > in " The

> > > > > > Puzzle of Autism: Putting it all Together " : (pgs 8-9)

> > > > > >

> > > > > > " Glutamate is the main excitatory neurotransmitter in the

> > body.

> > > > It is

> > > > > > essential for learning and for both short-term and long-term

> > > > memory.

> > > > > > It is also the precursor to the inhibitory neurotransmitter,

> > GABA.

> > > > > > GABA is a calming neurotransmitter and is essential for

> > speech.

> > > > GABA

> > > > > > neurons damp the propagation of sounds so that a distinction

> > can

> > > > be

> > > > > > made between the onset of a sound and background

> > noise....Problems

> > > > > > occur if the normal process of regulation of glutamate

> > > > malfunctions

> > > > > > and if toxic levels of this excitatory neurotransmitter

> > build up

> > > > in

> > > > > > the synaptic junctions.

> > > > > > The balance between glutamate and GABA is like a seesaw.

> > Under

> > > > normal

> > > > > > conditions, when the glutamate side gets too high, the GABA

> > side

> > > > of

> > > > > > the seesaw will increase and decrease the glutamate. Under

> > normal

> > > > > > functioning conditions, excess levels of the excitotoxin

> > glutamate

> > > > > > will convert to GABA. There seems to be a " disconnect " in

> > this

> > > > > > process for autistic children so that the excitatory

> > > > > > neurotransmission is high (stims) and the calming

> > > > neurotransmission

> > > > > > is low (lack of speech). When conditions occur that throw

> > off this

> > > > > > delicate balance, then high levels of glutamate can

> > accumulate

> > > > while

> > > > > > the levels of GABA remain exceedingly low. This would create

> > a

> > > > > > situation that would require decreasing the glutamate

> > levels, and

> > > > > > increasing the GABA levels in order to restore balance.

> > Chronic

> > > > viral

> > > > > > infection may be related to this disconnect between

> > glutamate and

> > > > > > GABA. "

> > > > > >

> > > > > > " Over seven years ago, Dr Blaylock described the

> > pathway

> > > > of

> > > > > > excitotoxin damage and the role it plays in neurological

> > damage

> > > > > > brilliantly in his landmark book on excitotoxins. He spelled

> > out

> > > > > > specifically how and why MSG, hydrolyzed vegetable protein,

> > > > aspartame

> > > > > > and related compounds have been proven to cause death of

> > neurons

> > > > > > beyond any reasonable doubt. More recently, this concept of

> > > > > > excitotoxin damage has been found to pertain to autism.

> > > > Excitotoxins

> > > > > > are neurotransmitters such as glutamate or aspartate

> > > > > > that can excite the nerves to death when their levels are

not

> > > > > > regulated properly. Foods or supplements that contain

> > excitotoxins

> > > > > > include MSG, glutamic acid, glutamine, Nutra Sweet,

> > aspartate,

> > > > > > aspartame and cysteine. Mercury and aluminum can trigger

> > glutamate

> > > > > > release. Minimizing glutatmate is a differentiating factor

> > in our

> > > > > > protocol and has helped many autistic children

> > significantly. "

> > > > > >

> > > > >

> > > >

> > > > ----------------------------------------------------------

> > -------

> > > >

> > > > No virus found in this incoming message.

> > > > Checked by AVG Free Edition.

> > > > Version: 7.5.488 / Virus Database: 269.13.30/1030 - Release

> > Date: 25/09/2007 08:02

> > > >

> > >

> >

>

September 29, 2007

Sorry, I'm totally lost here. Are you saying giving glutamine is good or that it's bad? have just started recently, seemed good at first, not so sure now???? Anyone had similar experiences?

>>it all depends on the indivdual child, good for some, not for others

Mandi x

September 29, 2007

Sorry, I'm totally lost here. Are you saying giving glutamine is good or that it's bad? have just started recently, seemed good at first, not so sure now???? Anyone had similar experiences?

September 30, 2007

It’s

very confusing. We’re saying that some people say it’s very good

and some people say it’s very bad. DAN! practitioners

tend to like it whereas Yasko doesn’t. SARA

-----Original

Message-----

From: Autism-Biomedical-Europe

[mailto:Autism-Biomedical-Europe ] On Behalf Of

Sent: 30 September 2007 01:05

To:

Autism-Biomedical-Europe

Subject:

Re: High glutamate and neuronal death

Sorry, I'm totally lost here. Are

you saying giving glutamine is good or that it's bad? have just started

recently, seemed good at first, not so sure now???? Anyone had similar

experiences?

September 30, 2007

For

a long time we didn’t give him calcium and he was casein free. I was a bit worried and that’s why we

kept trialling him on and off calcium but he kept reacting badly to it. I think

it might say in the vit k files that they use up what’s

been stored badly when you start vit k2 (don’t quote me on this). anyway

it was a toxin for his body.

Now

though he has some sheep’s yoghurt. Can’t say any of the old

calcium reactions and he takes a lot of K2. not

sure if all is rosy but he looks ok.

SARA

-----Original

Message-----

From:

Autism-Biomedical-Europe

[mailto:Autism-Biomedical-Europe ] On Behalf Of Scorer

Sent: 29 September 2007 15:14

To:

Autism-Biomedical-Europe

Subject:

Re: High glutamate and neuronal death

Hi Sara,

Thank you so much for sharing all of this, and copying Yasko's

explanation, you're a star!

From what you've said, am I correct that you are still not giving Tom

any calcium and that he is is also casein free? How else does he get

the calcium his body might need for bones, teeth etc.?

I think that doing a trial of on and off calcium may be something to

consider here and I will also go back and look at the vit K forum.

emily xx

> > > > > >

> > > > > > Hi Peta,

> > > > > >

> > > > > > Amy Yasko is really keen about reducing

glutamates and

> > > > supplementing

> > > > > > a small amount of Gaba.

> > > > > >

> > > > > > As well as avoiding overly glutamate foods this

also means

> > NOT

> > > > > > supplementing L-gluatime or using alpha keto

glutarates etc.

> > I

> > > > > > can't find a good summary on-line - I'll paste

what I could

> > find

> > > > > > below. We were supplementing l-glutamine a lot

before and

> > were

> > > > slow

> > > > > > to reduce and then remove it - but Eddie's

glutamine/gaba

> > have

> > > > > > actually balanced out. So while we were

supplementing he was

> > low

> > > > and

> > > > > > when we stopped he improved. The more I learn the

more I

like

> > > > Yasko -

> > > > > > it is doing great things for Eddie.

> > > > > >

> > > > > > Best wishes,

> > > > > > Sandy

> > > > > >

> > > > > > http://forums. <http://forums. about.com/ n/pfx/forum. aspx?

> > > > <http://forums. <http://forums.

> <http://forums.about.com/n/pfx/forum.aspx?>

about.com/n/pfx/forum.aspx?>

> > about.com/n/pfx/forum.aspx?>>

> > > > > about.com/n/ pfx/forum. aspx?

> > > > > > nav=printDiscussion & webtag=ab-

autism & tid= 4426

> > > > > > COPIED from this link ....

> > > > > > FYI, Here is some of what Dr Amy Yasko says about

glutamate

> > > > in " The

> > > > > > Puzzle of Autism: Putting it all Together " :

(pgs 8-9)

> > > > > >

> > > > > > " Glutamate is the main excitatory

neurotransmitter in the

> > body.

> > > > It is

> > > > > > essential for learning and for both short-term

and long-term

> > > > memory.

> > > > > > It is also the precursor to the inhibitory

neurotransmitter,

> > GABA.

> > > > > > GABA is a calming neurotransmitter and is

essential for

> > speech.

> > > > GABA

> > > > > > neurons damp the propagation of sounds so that a

distinction

> > can

> > > > be

> > > > > > made between the onset of a sound and background

> > noise....Problems

> > > > > > occur if the normal process of regulation of

glutamate

> > > > malfunctions

> > > > > > and if toxic levels of this excitatory

neurotransmitter

> > build up

> > > > in

> > > > > > the synaptic junctions.

> > > > > > The balance between glutamate and GABA is like a

seesaw.

> > Under

> > > > normal

> > > > > > conditions, when the glutamate side gets too

high, the GABA

> > side

> > > > of

> > > > > > the seesaw will increase and decrease the

glutamate. Under

> > normal

> > > > > > functioning conditions, excess levels of the

excitotoxin

> > glutamate

> > > > > > will convert to GABA. There seems to be a

" disconnect " in

> > this

> > > > > > process for autistic children so that the

excitatory

> > > > > > neurotransmission is high (stims) and the calming

> > > > neurotransmission

> > > > > > is low (lack of speech). When conditions occur

that throw

> > off this

> > > > > > delicate balance, then high levels of glutamate

can

> > accumulate

> > > > while

> > > > > > the levels of GABA remain exceedingly low. This

would create

> > a

> > > > > > situation that would require decreasing the

glutamate

> > levels, and

> > > > > > increasing the GABA levels in order to restore

balance.

> > Chronic

> > > > viral

> > > > > > infection may be related to this disconnect

between

> > glutamate and

> > > > > > GABA. "

> > > > > >

> > > > > > " Over seven years ago, Dr Blaylock

described the

> > pathway

> > > > of

> > > > > > excitotoxin damage and the role it plays in

neurological

> > damage

> > > > > > brilliantly in his landmark book on excitotoxins.

He spelled

> > out

> > > > > > specifically how and why MSG, hydrolyzed vegetable

protein,

> > > > aspartame

> > > > > > and related compounds have been proven to cause

death of

> > neurons

> > > > > > beyond any reasonable doubt. More recently, this

concept of

> > > > > > excitotoxin damage has been found to pertain to

autism.

> > > > Excitotoxins

> > > > > > are neurotransmitters such as glutamate or

aspartate

> > > > > > that can excite the nerves to death when their

levels are

not

> > > > > > regulated properly. Foods or supplements that

contain

> > excitotoxins

> > > > > > include MSG, glutamic acid, glutamine, Nutra

Sweet,

> > aspartate,

> > > > > > aspartame and cysteine. Mercury and aluminum can

trigger

> > glutamate

> > > > > > release. Minimizing glutatmate is a

differentiating factor

> > in our

> > > > > > protocol and has helped many autistic children

> > significantly. "

> > > > > >

> > > > >

> > > >

> > > > ----------------------------------------------------------

> > -------

> > > >

> > > > No virus found in this incoming message.

> > > > Checked by AVG Free Edition.

> > > > Version: 7.5.488 / Virus Database: 269.13.30/1030 - Release

> > Date: 25/09/2007 08:02

> > > >

> > >

> >

>

September 30, 2007

Hello All

AFAIK glutamate causes brain cells to be hyperactive. These cells then

burn out so the excitoxin in the glutamate literally excites cells to

death.

There are some books around on excitoxins.

HTH anyone who was confused

is (who avoids MSG as it contains glutamate and limits mushrooms

for the same reason)

Sign In

Re: High glutamate and neuronal death

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