Re: High glutamate and neuronal death

[Guest guest]

Who provide the test,

and what is " the name " of the test...

Geir Flatabø

2007/9/25, peta3366 :

hi we had a glutamate toxicity test and the upper level is 35.Charlie's is 104 and my dr said the results are really horrible.

Anything over 100 means neuronal death. It's to do with the micrgliaand he is not converting glutamte to Gaba. So more drugs and trying toavoid high glutamte foods. Is there anything in the files about this? I

have looked but couldn't find it. God I'm pissed off with everything inhis body not working - still if all else fails Beachy Head is on ourdoorstep!Thanks for your helpPetaDISCLAIMER

No information contained in this post is to be construed as medical advice. If you need medical advice, please seek it from a suitably qualified practitioner.

[Guest guest]

Peta, have TACA or ARI gto any files, this is mentioned in the new

Jepson Book.

Lara x

>

> hi we had a glutamate toxicity test and the upper level is 35.

> Charlie's is 104 and my dr said the results are really horrible.

> Anything over 100 means neuronal death. It's to do with the micrglia

> and he is not converting glutamte to Gaba. So more drugs and trying to

> avoid high glutamte foods. Is there anything in the files about this? I

> have looked but couldn't find it. God I'm pissed off with everything in

> his body not working - still if all else fails Beachy Head is on our

> doorstep!

> Thanks for your help

> Peta

>

[Guest guest]

Peta,

I have read that grape seed extract and Idbenone help block glutamates.

Re: High glutamate and neuronal death

Who provide the test,

and what is "the name" of the test...

Geir Flatabø

2007/9/25, peta3366 <peta3366yahoo (DOT) co.uk>: hi we had a glutamate toxicity test and the upper level is 35.Charlie's is 104 and my dr said the results are really horrible. Anything over 100 means neuronal death. It's to do with the micrgliaand he is not converting glutamte to Gaba. So more drugs and trying toavoid high glutamte foods. Is there anything in the files about this? I have looked but couldn't find it. God I'm pissed off with everything inhis body not working - still if all else fails Beachy Head is on ourdoorstep!Thanks for your helpPetaDISCLAIMER No information contained in this post is to be construed as medical advice. If you need medical advice, please seek it from a suitably qualified practitioner.

[Guest guest]

I read that magnesium is wasted in the urine if sugar metabolism problematic. You need B6 and magnesium to convert the glutamate to GABA. Maybe you can concentrate on the sugar issue first and the GABA might come by itself. I know when I had a terrific problem with a frozen shoulder my GP told me to pump in Mg but when we got the blood tests back I was extremely deficient. I couldn't figure out why until I got to this glucose metabolism issue.

Just an idea....

High glutamate and neuronal death

hi we had a glutamate toxicity test and the upper level is 35. Charlie's is 104 and my dr said the results are really horrible. Anything over 100 means neuronal death. It's to do with the micrglia and he is not converting glutamte to Gaba. So more drugs and trying to avoid high glutamte foods. Is there anything in the files about this? I have looked but couldn't find it. God I'm pissed off with everything in his body not working - still if all else fails Beachy Head is on our doorstep!Thanks for your helpPeta

[Guest guest]

" You need B6 and magnesium to convert the glutamate to GABA "

hi , this is new to me, could you post some more info on this?

studies?

tia

natasa

>

> I read that magnesium is wasted in the urine if sugar metabolism

problematic. You need B6 and magnesium to convert the glutamate to GABA.

Maybe you can concentrate on the sugar issue first and the GABA might

come by itself. I know when I had a terrific problem with a frozen

shoulder my GP told me to pump in Mg but when we got the blood tests

back I was extremely deficient. I couldn't figure out why until I got to

this glucose metabolism issue.

>

> Just an idea....

> High glutamate and neuronal

death

>

>

> hi we had a glutamate toxicity test and the upper level is 35.

> Charlie's is 104 and my dr said the results are really horrible.

> Anything over 100 means neuronal death. It's to do with the micrglia

> and he is not converting glutamte to Gaba. So more drugs and trying

to

> avoid high glutamte foods. Is there anything in the files about

this? I

> have looked but couldn't find it. God I'm pissed off with everything

in

> his body not working - still if all else fails Beachy Head is on our

> doorstep!

> Thanks for your help

> Peta

>

[Guest guest]

Natasa, I did a lot of work on glutamates some time back and the B6/mag stands out in my mind but having done a quick search I can I only find the B6 connection but not the Mg.

There is a well-known study of B6/mag having a very calming effect on ADHD children. I put it down to GABA.

Hmm When I have a moment I'll have a look again.

High glutamate and neuronaldeath>>> hi we had a glutamate toxicity test and the upper level is 35.> Charlie's is 104 and my dr said the results are really horrible.> Anything over 100 means neuronal death. It's to do with the micrglia> and he is not converting glutamte to Gaba. So more drugs and tryingto> avoid high glutamte foods. Is there anything in the files aboutthis? I> have looked but couldn't find it. God I'm pissed off with everythingin> his body not working - still if all else fails Beachy Head is on our> doorstep!> Thanks for your help> Peta>

[Guest guest]

Hi Peta,

Amy Yasko is really keen about reducing glutamates and supplementing

a small amount of Gaba.

As well as avoiding overly glutamate foods this also means NOT

supplementing L-gluatime or using alpha keto glutarates etc. I

can't find a good summary on-line - I'll paste what I could find

below. We were supplementing l-glutamine a lot before and were slow

to reduce and then remove it - but Eddie's glutamine/gaba have

actually balanced out. So while we were supplementing he was low and

when we stopped he improved. The more I learn the more I like Yasko -

it is doing great things for Eddie.

Best wishes,

Sandy

http://forums.about.com/n/pfx/forum.aspx?

nav=printDiscussion & webtag=ab-autism & tid=4426

COPIED from this link ....

FYI, Here is some of what Dr Amy Yasko says about glutamate in " The

Puzzle of Autism: Putting it all Together " : (pgs 8-9)

" Glutamate is the main excitatory neurotransmitter in the body. It is

essential for learning and for both short-term and long-term memory.

It is also the precursor to the inhibitory neurotransmitter, GABA.

GABA is a calming neurotransmitter and is essential for speech. GABA

neurons damp the propagation of sounds so that a distinction can be

made between the onset of a sound and background noise....Problems

occur if the normal process of regulation of glutamate malfunctions

and if toxic levels of this excitatory neurotransmitter build up in

the synaptic junctions.

The balance between glutamate and GABA is like a seesaw. Under normal

conditions, when the glutamate side gets too high, the GABA side of

the seesaw will increase and decrease the glutamate. Under normal

functioning conditions, excess levels of the excitotoxin glutamate

will convert to GABA. There seems to be a " disconnect " in this

process for autistic children so that the excitatory

neurotransmission is high (stims) and the calming neurotransmission

is low (lack of speech). When conditions occur that throw off this

delicate balance, then high levels of glutamate can accumulate while

the levels of GABA remain exceedingly low. This would create a

situation that would require decreasing the glutamate levels, and

increasing the GABA levels in order to restore balance. Chronic viral

infection may be related to this disconnect between glutamate and

GABA. "

" Over seven years ago, Dr Blaylock described the pathway of

excitotoxin damage and the role it plays in neurological damage

brilliantly in his landmark book on excitotoxins. He spelled out

specifically how and why MSG, hydrolyzed vegetable protein, aspartame

and related compounds have been proven to cause death of neurons

beyond any reasonable doubt. More recently, this concept of

excitotoxin damage has been found to pertain to autism. Excitotoxins

are neurotransmitters such as glutamate or aspartate

that can excite the nerves to death when their levels are not

regulated properly. Foods or supplements that contain excitotoxins

include MSG, glutamic acid, glutamine, Nutra Sweet, aspartate,

aspartame and cysteine. Mercury and aluminum can trigger glutamate

release. Minimizing glutatmate is a differentiating factor in our

protocol and has helped many autistic children significantly. "

[Guest guest]

Hi we are with Bradstreet's clinic who ordered the test ( urine) and

it's through Neuroscience www.NeuroRelief.com- or www.Pharmasan.com.

i haven't looked at the sites.

Peta

-- In Autism-Biomedical-Europe , " Geir Flatabø "

wrote:

>

> Who provide the test,

> and what is " the name " of the test...

>

> Geir Flatabø

>

>

> 2007/9/25, peta3366 :

> >

> > hi we had a glutamate toxicity test and the upper level is 35.

> > Charlie's is 104 and my dr said the results are really horrible.

> > Anything over 100 means neuronal death. It's to do with the

micrglia

> > and he is not converting glutamte to Gaba. So more drugs and

trying to

> > avoid high glutamte foods. Is there anything in the files about

this? I

> > have looked but couldn't find it. God I'm pissed off with

everything in

> > his body not working - still if all else fails Beachy Head is on

our

> > doorstep!

> > Thanks for your help

> > Peta

> >

> >

> >

> > DISCLAIMER

> > No information contained in this post is to be construed as

medical

> > advice. If you need medical advice, please seek it from a

suitably qualified

> > practitioner.

> >

> >

[Guest guest]

Thanks Lara

What do you mean?

Peta--

- In Autism-Biomedical-Europe , " Lara "

wrote:

>

> Peta, have TACA or ARI gto any files, this is mentioned in the new

> Jepson Book.

>

> Lara x

>

>

>

>

> >

> > hi we had a glutamate toxicity test and the upper level is 35.

> > Charlie's is 104 and my dr said the results are really horrible.

> > Anything over 100 means neuronal death. It's to do with the

micrglia

> > and he is not converting glutamte to Gaba. So more drugs and

trying to

> > avoid high glutamte foods. Is there anything in the files about

this? I

> > have looked but couldn't find it. God I'm pissed off with

everything in

> > his body not working - still if all else fails Beachy Head is on

our

> > doorstep!

> > Thanks for your help

> > Peta

> >

>

[Guest guest]

Thanks we supplement magnesium and B6 and we recently did a sulphate

test which was normal. We also give lots of epsom salts. We are low

sugar - all he has is a bit of honey on bread. I don't bake with any

sugar.

Peta-

-- In Autism-Biomedical-Europe , " JULIE GRIFFITHS "

wrote:

>

> I read that magnesium is wasted in the urine if sugar metabolism

problematic. You need B6 and magnesium to convert the glutamate to

GABA. Maybe you can concentrate on the sugar issue first and the GABA

might come by itself. I know when I had a terrific problem with a

frozen shoulder my GP told me to pump in Mg but when we got the blood

tests back I was extremely deficient. I couldn't figure out why until

I got to this glucose metabolism issue.

>

> Just an idea....

> High glutamate and neuronal

death

>

>

> hi we had a glutamate toxicity test and the upper level is 35.

> Charlie's is 104 and my dr said the results are really horrible.

> Anything over 100 means neuronal death. It's to do with the

micrglia

> and he is not converting glutamte to Gaba. So more drugs and

trying to

> avoid high glutamte foods. Is there anything in the files about

this? I

> have looked but couldn't find it. God I'm pissed off with

everything in

> his body not working - still if all else fails Beachy Head is on

our

> doorstep!

> Thanks for your help

> Peta

>

[Guest guest]

Thanks Sandy that's very interesting. When we tried to supplement

Gaba he did very strange mouthing which stopped when we stopped the

Gaba. Our dr has advised campral which converts glutamate to gaba.

Another choice was rilutek but that is $900 per month!

I am very strict with his diet - definitely no additives.

Peta

>

> Hi Peta,

>

> Amy Yasko is really keen about reducing glutamates and

supplementing

> a small amount of Gaba.

>

> As well as avoiding overly glutamate foods this also means NOT

> supplementing L-gluatime or using alpha keto glutarates etc. I

> can't find a good summary on-line - I'll paste what I could find

> below. We were supplementing l-glutamine a lot before and were

slow

> to reduce and then remove it - but Eddie's glutamine/gaba have

> actually balanced out. So while we were supplementing he was low

and

> when we stopped he improved. The more I learn the more I like

Yasko -

> it is doing great things for Eddie.

>

> Best wishes,

> Sandy

>

> http://forums.about.com/n/pfx/forum.aspx?

> nav=printDiscussion & webtag=ab-autism & tid=4426

> COPIED from this link ....

> FYI, Here is some of what Dr Amy Yasko says about glutamate in " The

> Puzzle of Autism: Putting it all Together " : (pgs 8-9)

>

> " Glutamate is the main excitatory neurotransmitter in the body. It

is

> essential for learning and for both short-term and long-term

memory.

> It is also the precursor to the inhibitory neurotransmitter, GABA.

> GABA is a calming neurotransmitter and is essential for speech.

GABA

> neurons damp the propagation of sounds so that a distinction can be

> made between the onset of a sound and background noise....Problems

> occur if the normal process of regulation of glutamate malfunctions

> and if toxic levels of this excitatory neurotransmitter build up in

> the synaptic junctions.

> The balance between glutamate and GABA is like a seesaw. Under

normal

> conditions, when the glutamate side gets too high, the GABA side of

> the seesaw will increase and decrease the glutamate. Under normal

> functioning conditions, excess levels of the excitotoxin glutamate

> will convert to GABA. There seems to be a " disconnect " in this

> process for autistic children so that the excitatory

> neurotransmission is high (stims) and the calming neurotransmission

> is low (lack of speech). When conditions occur that throw off this

> delicate balance, then high levels of glutamate can accumulate

while

> the levels of GABA remain exceedingly low. This would create a

> situation that would require decreasing the glutamate levels, and

> increasing the GABA levels in order to restore balance. Chronic

viral

> infection may be related to this disconnect between glutamate and

> GABA. "

>

> " Over seven years ago, Dr Blaylock described the pathway of

> excitotoxin damage and the role it plays in neurological damage

> brilliantly in his landmark book on excitotoxins. He spelled out

> specifically how and why MSG, hydrolyzed vegetable protein,

aspartame

> and related compounds have been proven to cause death of neurons

> beyond any reasonable doubt. More recently, this concept of

> excitotoxin damage has been found to pertain to autism.

Excitotoxins

> are neurotransmitters such as glutamate or aspartate

> that can excite the nerves to death when their levels are not

> regulated properly. Foods or supplements that contain excitotoxins

> include MSG, glutamic acid, glutamine, Nutra Sweet, aspartate,

> aspartame and cysteine. Mercury and aluminum can trigger glutamate

> release. Minimizing glutatmate is a differentiating factor in our

> protocol and has helped many autistic children significantly. "

>

[Guest guest]

Just butting in. L-Glutamine was recommended for DS I asked Loreneabout it glutamine affecting/increasing the glutamate levels, she saidthat it doesn't. I'm confused about this is anyone able to clarify orpoint me to any reading material!

>>I think you'd end up more confused at the Yasko site I certainly do LOL but there are clever peeps who understand it.

Mandi x

[Guest guest]

Just butting in. L-Glutamine was recommended for DS I asked Loreneabout it glutamine affecting/increasing the glutamate levels, she saidthat it doesn't. I'm confused about this is anyone able to clarify orpoint me to any reading material!

>>I think you'd end up more confused at the Yasko site I certainly do LOL but there are clever peeps who understand it.

Mandi x

[Guest guest]

Hi,

Just butting in. L-Glutamine was recommended for DS I asked Lorene

about it glutamine affecting/increasing the glutamate levels, she said

that it doesn't. I'm confused about this is anyone able to clarify or

point me to any reading material!

thanks,

emily

>

> Hi Peta,

>

> Amy Yasko is really keen about reducing glutamates and supplementing

> a small amount of Gaba.

>

> As well as avoiding overly glutamate foods this also means NOT

> supplementing L-gluatime or using alpha keto glutarates etc. I

> can't find a good summary on-line - I'll paste what I could find

> below. We were supplementing l-glutamine a lot before and were slow

> to reduce and then remove it - but Eddie's glutamine/gaba have

> actually balanced out. So while we were supplementing he was low and

> when we stopped he improved. The more I learn the more I like Yasko -

> it is doing great things for Eddie.

>

> Best wishes,

> Sandy

>

> http://forums.about.com/n/pfx/forum.aspx?

> nav=printDiscussion & webtag=ab-autism & tid=4426

> COPIED from this link ....

> FYI, Here is some of what Dr Amy Yasko says about glutamate in " The

> Puzzle of Autism: Putting it all Together " : (pgs 8-9)

>

> " Glutamate is the main excitatory neurotransmitter in the body. It is

> essential for learning and for both short-term and long-term memory.

> It is also the precursor to the inhibitory neurotransmitter, GABA.

> GABA is a calming neurotransmitter and is essential for speech. GABA

> neurons damp the propagation of sounds so that a distinction can be

> made between the onset of a sound and background noise....Problems

> occur if the normal process of regulation of glutamate malfunctions

> and if toxic levels of this excitatory neurotransmitter build up in

> the synaptic junctions.

> The balance between glutamate and GABA is like a seesaw. Under normal

> conditions, when the glutamate side gets too high, the GABA side of

> the seesaw will increase and decrease the glutamate. Under normal

> functioning conditions, excess levels of the excitotoxin glutamate

> will convert to GABA. There seems to be a " disconnect " in this

> process for autistic children so that the excitatory

> neurotransmission is high (stims) and the calming neurotransmission

> is low (lack of speech). When conditions occur that throw off this

> delicate balance, then high levels of glutamate can accumulate while

> the levels of GABA remain exceedingly low. This would create a

> situation that would require decreasing the glutamate levels, and

> increasing the GABA levels in order to restore balance. Chronic viral

> infection may be related to this disconnect between glutamate and

> GABA. "

>

> " Over seven years ago, Dr Blaylock described the pathway of

> excitotoxin damage and the role it plays in neurological damage

> brilliantly in his landmark book on excitotoxins. He spelled out

> specifically how and why MSG, hydrolyzed vegetable protein, aspartame

> and related compounds have been proven to cause death of neurons

> beyond any reasonable doubt. More recently, this concept of

> excitotoxin damage has been found to pertain to autism. Excitotoxins

> are neurotransmitters such as glutamate or aspartate

> that can excite the nerves to death when their levels are not

> regulated properly. Foods or supplements that contain excitotoxins

> include MSG, glutamic acid, glutamine, Nutra Sweet, aspartate,

> aspartame and cysteine. Mercury and aluminum can trigger glutamate

> release. Minimizing glutatmate is a differentiating factor in our

> protocol and has helped many autistic children significantly. "

>

[Guest guest]

Hi

,

In

Yasko’s book ‘the puzzle of autism’ she says ‘Excitotoxins

will continue to damage more nerves and wreak more havoc in the body if they

are not addressed…This is an area where we encounter disagreement with

some of our colleagues (she means DAN! here I assume)…Due to a basic lack

of understanding about the involved chemistry, we find that glutamic acid,

glutamine, etc are still being included in supplement regimes for their

potential gastro-intestinal benefits, while their documented potential for contributing

to the proven neurotoxic effects are being ignored.”

Don’t

know if that helps but basically it says to me that DAN! doctors

and Yasko disagree on this.

Sara

-----Original

Message-----

From: Autism-Biomedical-Europe

[mailto:Autism-Biomedical-Europe ] On Behalf Of Scorer

Sent: 27

September 2007

22:44

To:

Autism-Biomedical-Europe

Subject:

Re: High glutamate and neuronal death

Hi,

Just butting in. L-Glutamine was recommended for DS I asked Lorene

about it glutamine affecting/increasing the glutamate levels, she said

that it doesn't. I'm confused about this is anyone able to clarify or

point me to any reading material!

thanks,

emily

>

> Hi Peta,

>

> Amy Yasko is really keen about reducing glutamates and supplementing

> a small amount of Gaba.

>

> As well as avoiding overly glutamate foods this also means NOT

> supplementing L-gluatime or using alpha keto glutarates etc. I

> can't find a good summary on-line - I'll paste what I could find

> below. We were supplementing l-glutamine a lot before and were slow

> to reduce and then remove it - but Eddie's glutamine/gaba have

> actually balanced out. So while we were supplementing he was low and

> when we stopped he improved. The more I learn the more I like Yasko -

> it is doing great things for Eddie.

>

> Best wishes,

> Sandy

>

> http://forums.about.com/n/pfx/forum.aspx?

> nav=printDiscussion & webtag=ab-autism & tid=4426

> COPIED from this link ....

> FYI, Here is some of what Dr Amy Yasko says about glutamate in " The

> Puzzle of Autism: Putting it all Together " : (pgs 8-9)

>

> " Glutamate is the main excitatory neurotransmitter in the body. It is

> essential for learning and for both short-term and long-term memory.

> It is also the precursor to the inhibitory neurotransmitter, GABA.

> GABA is a calming neurotransmitter and is essential for speech. GABA

> neurons damp the propagation of sounds so that a distinction can be

> made between the onset of a sound and background noise....Problems

> occur if the normal process of regulation of glutamate malfunctions

> and if toxic levels of this excitatory neurotransmitter build up in

> the synaptic junctions.

> The balance between glutamate and GABA is like a seesaw. Under normal

> conditions, when the glutamate side gets too high, the GABA side of

> the seesaw will increase and decrease the glutamate. Under normal

> functioning conditions, excess levels of the excitotoxin glutamate

> will convert to GABA. There seems to be a " disconnect " in this

> process for autistic children so that the excitatory

> neurotransmission is high (stims) and the calming neurotransmission

> is low (lack of speech). When conditions occur that throw off this

> delicate balance, then high levels of glutamate can accumulate while

> the levels of GABA remain exceedingly low. This would create a

> situation that would require decreasing the glutamate levels, and

> increasing the GABA levels in order to restore balance. Chronic viral

> infection may be related to this disconnect between glutamate and

> GABA. "

>

> " Over seven years ago, Dr Blaylock described the pathway of

> excitotoxin damage and the role it plays in neurological damage

> brilliantly in his landmark book on excitotoxins. He spelled out

> specifically how and why MSG, hydrolyzed vegetable protein, aspartame

> and related compounds have been proven to cause death of neurons

> beyond any reasonable doubt. More recently, this concept of

> excitotoxin damage has been found to pertain to autism. Excitotoxins

> are neurotransmitters such as glutamate or aspartate

> that can excite the nerves to death when their levels are not

> regulated properly. Foods or supplements that contain excitotoxins

> include MSG, glutamic acid, glutamine, Nutra Sweet, aspartate,

> aspartame and cysteine. Mercury and aluminum can trigger glutamate

> release. Minimizing glutatmate is a differentiating factor in our

> protocol and has helped many autistic children significantly. "

>

[Guest guest]

Hi

,

In

Yasko’s book ‘the puzzle of autism’ she says ‘Excitotoxins

will continue to damage more nerves and wreak more havoc in the body if they

are not addressed…This is an area where we encounter disagreement with

some of our colleagues (she means DAN! here I assume)…Due to a basic lack

of understanding about the involved chemistry, we find that glutamic acid,

glutamine, etc are still being included in supplement regimes for their

potential gastro-intestinal benefits, while their documented potential for contributing

to the proven neurotoxic effects are being ignored.”

Don’t

know if that helps but basically it says to me that DAN! doctors

and Yasko disagree on this.

Sara

-----Original

Message-----

From: Autism-Biomedical-Europe

[mailto:Autism-Biomedical-Europe ] On Behalf Of Scorer

Sent: 27

September 2007

22:44

To:

Autism-Biomedical-Europe

Subject:

Re: High glutamate and neuronal death

Hi,

Just butting in. L-Glutamine was recommended for DS I asked Lorene

about it glutamine affecting/increasing the glutamate levels, she said

that it doesn't. I'm confused about this is anyone able to clarify or

point me to any reading material!

thanks,

emily

>

> Hi Peta,

>

> Amy Yasko is really keen about reducing glutamates and supplementing

> a small amount of Gaba.

>

> As well as avoiding overly glutamate foods this also means NOT

> supplementing L-gluatime or using alpha keto glutarates etc. I

> can't find a good summary on-line - I'll paste what I could find

> below. We were supplementing l-glutamine a lot before and were slow

> to reduce and then remove it - but Eddie's glutamine/gaba have

> actually balanced out. So while we were supplementing he was low and

> when we stopped he improved. The more I learn the more I like Yasko -

> it is doing great things for Eddie.

>

> Best wishes,

> Sandy

>

> http://forums.about.com/n/pfx/forum.aspx?

> nav=printDiscussion & webtag=ab-autism & tid=4426

> COPIED from this link ....

> FYI, Here is some of what Dr Amy Yasko says about glutamate in " The

> Puzzle of Autism: Putting it all Together " : (pgs 8-9)

>

> " Glutamate is the main excitatory neurotransmitter in the body. It is

> essential for learning and for both short-term and long-term memory.

> It is also the precursor to the inhibitory neurotransmitter, GABA.

> GABA is a calming neurotransmitter and is essential for speech. GABA

> neurons damp the propagation of sounds so that a distinction can be

> made between the onset of a sound and background noise....Problems

> occur if the normal process of regulation of glutamate malfunctions

> and if toxic levels of this excitatory neurotransmitter build up in

> the synaptic junctions.

> The balance between glutamate and GABA is like a seesaw. Under normal

> conditions, when the glutamate side gets too high, the GABA side of

> the seesaw will increase and decrease the glutamate. Under normal

> functioning conditions, excess levels of the excitotoxin glutamate

> will convert to GABA. There seems to be a " disconnect " in this

> process for autistic children so that the excitatory

> neurotransmission is high (stims) and the calming neurotransmission

> is low (lack of speech). When conditions occur that throw off this

> delicate balance, then high levels of glutamate can accumulate while

> the levels of GABA remain exceedingly low. This would create a

> situation that would require decreasing the glutamate levels, and

> increasing the GABA levels in order to restore balance. Chronic viral

> infection may be related to this disconnect between glutamate and

> GABA. "

>

> " Over seven years ago, Dr Blaylock described the pathway of

> excitotoxin damage and the role it plays in neurological damage

> brilliantly in his landmark book on excitotoxins. He spelled out

> specifically how and why MSG, hydrolyzed vegetable protein, aspartame

> and related compounds have been proven to cause death of neurons

> beyond any reasonable doubt. More recently, this concept of

> excitotoxin damage has been found to pertain to autism. Excitotoxins

> are neurotransmitters such as glutamate or aspartate

> that can excite the nerves to death when their levels are not

> regulated properly. Foods or supplements that contain excitotoxins

> include MSG, glutamic acid, glutamine, Nutra Sweet, aspartate,

> aspartame and cysteine. Mercury and aluminum can trigger glutamate

> release. Minimizing glutatmate is a differentiating factor in our

> protocol and has helped many autistic children significantly. "

>

[Guest guest]

One of the causes that I am considering for Edith's prolonged " seizures "

earlier in the year is a chinese meal full of MSG which we had (some

time) before. The time lag was quite considerable so this may not be

right. Also I gave Edith some free stuff from the conference called

Mindlinks which contains glutamine as well as probiotics. I felt that

this was making her seizures worse and gave it away. I don't know as in

know in hard fact that there is a connection.There felt like one but it

could be co-incidence. The most likely explanation which doctors seem to

be settling on is a infection causing a sub-acute encephalitis which is

going away.

The glutamine shouldn't matter because it should be changed in the body

but the research I posted a few days ago suggested that part of autism

might be a genetic difficulty in changing glutamine from an excitatory

to an inhibitory neurotransmitter. Natasa said the difficulty might not

be genetic but functional (ie environmentally caused, I guess) but in

practice the effect would be the same.

However I've never heard of the test and the possibility that it is a

big load of nonsense should be considered before doing anything drastic.

xx Sally

Sass and Rem wrote:

>

> Hi ,

>

> In Yasko’s book ‘the puzzle of autism’ she says ‘Excitotoxins will

> continue to damage more nerves and wreak more havoc in the body if

> they are not addressed…This is an area where we encounter disagreement

> with some of our colleagues (she means DAN! here I assume)…Due to a

> basic lack of understanding about the involved chemistry, we find that

> glutamic acid, glutamine, etc are still being included in supplement

> regimes for their potential gastro-intestinal benefits, while their

> documented potential for contributing to the proven neurotoxic effects

> are being ignored.”

>

> Don’t know if that helps but basically it says to me that DAN! doctors

> and Yasko disagree on this.

>

> Sara

>

> * [Autism-Biomedical- Europe] Re: High glutamate and neuronal

> death

>

>

> Hi,

>

> Just butting in. L-Glutamine was recommended for DS I asked Lorene

> about it glutamine affecting/increasin g the glutamate levels, she said

> that it doesn't. I'm confused about this is anyone able to clarify or

> point me to any reading material!

>

> thanks,

>

> emily

>

>

> >

> > Hi Peta,

> >

> > Amy Yasko is really keen about reducing glutamates and supplementing

> > a small amount of Gaba.

> >

> > As well as avoiding overly glutamate foods this also means NOT

> > supplementing L-gluatime or using alpha keto glutarates etc. I

> > can't find a good summary on-line - I'll paste what I could find

> > below. We were supplementing l-glutamine a lot before and were slow

> > to reduce and then remove it - but Eddie's glutamine/gaba have

> > actually balanced out. So while we were supplementing he was low and

> > when we stopped he improved. The more I learn the more I like Yasko -

> > it is doing great things for Eddie.

> >

> > Best wishes,

> > Sandy

> >

> > http://forums. about.com/ n/pfx/forum. aspx?

> <http://forums.about.com/n/pfx/forum.aspx?>

> > nav=printDiscussion & webtag=ab- autism & tid= 4426

> > COPIED from this link ....

> > FYI, Here is some of what Dr Amy Yasko says about glutamate in " The

> > Puzzle of Autism: Putting it all Together " : (pgs 8-9)

> >

> > " Glutamate is the main excitatory neurotransmitter in the body. It is

> > essential for learning and for both short-term and long-term memory.

> > It is also the precursor to the inhibitory neurotransmitter, GABA.

> > GABA is a calming neurotransmitter and is essential for speech. GABA

> > neurons damp the propagation of sounds so that a distinction can be

> > made between the onset of a sound and background noise....Problems

> > occur if the normal process of regulation of glutamate malfunctions

> > and if toxic levels of this excitatory neurotransmitter build up in

> > the synaptic junctions.

> > The balance between glutamate and GABA is like a seesaw. Under normal

> > conditions, when the glutamate side gets too high, the GABA side of

> > the seesaw will increase and decrease the glutamate. Under normal

> > functioning conditions, excess levels of the excitotoxin glutamate

> > will convert to GABA. There seems to be a " disconnect " in this

> > process for autistic children so that the excitatory

> > neurotransmission is high (stims) and the calming neurotransmission

> > is low (lack of speech). When conditions occur that throw off this

> > delicate balance, then high levels of glutamate can accumulate while

> > the levels of GABA remain exceedingly low. This would create a

> > situation that would require decreasing the glutamate levels, and

> > increasing the GABA levels in order to restore balance. Chronic viral

> > infection may be related to this disconnect between glutamate and

> > GABA. "

> >

> > " Over seven years ago, Dr Blaylock described the pathway of

> > excitotoxin damage and the role it plays in neurological damage

> > brilliantly in his landmark book on excitotoxins. He spelled out

> > specifically how and why MSG, hydrolyzed vegetable protein, aspartame

> > and related compounds have been proven to cause death of neurons

> > beyond any reasonable doubt. More recently, this concept of

> > excitotoxin damage has been found to pertain to autism. Excitotoxins

> > are neurotransmitters such as glutamate or aspartate

> > that can excite the nerves to death when their levels are not

> > regulated properly. Foods or supplements that contain excitotoxins

> > include MSG, glutamic acid, glutamine, Nutra Sweet, aspartate,

> > aspartame and cysteine. Mercury and aluminum can trigger glutamate

> > release. Minimizing glutatmate is a differentiating factor in our

> > protocol and has helped many autistic children significantly. "

> >

>

>

> ------------------------------------------------------------------------

>

> No virus found in this incoming message.

> Checked by AVG Free Edition.

> Version: 7.5.488 / Virus Database: 269.13.30/1030 - Release Date: 25/09/2007

08:02

>

[Guest guest]

One of the causes that I am considering for Edith's prolonged " seizures "

earlier in the year is a chinese meal full of MSG which we had (some

time) before. The time lag was quite considerable so this may not be

right. Also I gave Edith some free stuff from the conference called

Mindlinks which contains glutamine as well as probiotics. I felt that

this was making her seizures worse and gave it away. I don't know as in

know in hard fact that there is a connection.There felt like one but it

could be co-incidence. The most likely explanation which doctors seem to

be settling on is a infection causing a sub-acute encephalitis which is

going away.

The glutamine shouldn't matter because it should be changed in the body

but the research I posted a few days ago suggested that part of autism

might be a genetic difficulty in changing glutamine from an excitatory

to an inhibitory neurotransmitter. Natasa said the difficulty might not

be genetic but functional (ie environmentally caused, I guess) but in

practice the effect would be the same.

However I've never heard of the test and the possibility that it is a

big load of nonsense should be considered before doing anything drastic.

xx Sally

Sass and Rem wrote:

>

> Hi ,

>

> In Yasko’s book ‘the puzzle of autism’ she says ‘Excitotoxins will

> continue to damage more nerves and wreak more havoc in the body if

> they are not addressed…This is an area where we encounter disagreement

> with some of our colleagues (she means DAN! here I assume)…Due to a

> basic lack of understanding about the involved chemistry, we find that

> glutamic acid, glutamine, etc are still being included in supplement

> regimes for their potential gastro-intestinal benefits, while their

> documented potential for contributing to the proven neurotoxic effects

> are being ignored.”

>

> Don’t know if that helps but basically it says to me that DAN! doctors

> and Yasko disagree on this.

>

> Sara

>

> * [Autism-Biomedical- Europe] Re: High glutamate and neuronal

> death

>

>

> Hi,

>

> Just butting in. L-Glutamine was recommended for DS I asked Lorene

> about it glutamine affecting/increasin g the glutamate levels, she said

> that it doesn't. I'm confused about this is anyone able to clarify or

> point me to any reading material!

>

> thanks,

>

> emily

>

>

> >

> > Hi Peta,

> >

> > Amy Yasko is really keen about reducing glutamates and supplementing

> > a small amount of Gaba.

> >

> > As well as avoiding overly glutamate foods this also means NOT

> > supplementing L-gluatime or using alpha keto glutarates etc. I

> > can't find a good summary on-line - I'll paste what I could find

> > below. We were supplementing l-glutamine a lot before and were slow

> > to reduce and then remove it - but Eddie's glutamine/gaba have

> > actually balanced out. So while we were supplementing he was low and

> > when we stopped he improved. The more I learn the more I like Yasko -

> > it is doing great things for Eddie.

> >

> > Best wishes,

> > Sandy

> >

> > http://forums. about.com/ n/pfx/forum. aspx?

> <http://forums.about.com/n/pfx/forum.aspx?>

> > nav=printDiscussion & webtag=ab- autism & tid= 4426

> > COPIED from this link ....

> > FYI, Here is some of what Dr Amy Yasko says about glutamate in " The

> > Puzzle of Autism: Putting it all Together " : (pgs 8-9)

> >

> > " Glutamate is the main excitatory neurotransmitter in the body. It is

> > essential for learning and for both short-term and long-term memory.

> > It is also the precursor to the inhibitory neurotransmitter, GABA.

> > GABA is a calming neurotransmitter and is essential for speech. GABA

> > neurons damp the propagation of sounds so that a distinction can be

> > made between the onset of a sound and background noise....Problems

> > occur if the normal process of regulation of glutamate malfunctions

> > and if toxic levels of this excitatory neurotransmitter build up in

> > the synaptic junctions.

> > The balance between glutamate and GABA is like a seesaw. Under normal

> > conditions, when the glutamate side gets too high, the GABA side of

> > the seesaw will increase and decrease the glutamate. Under normal

> > functioning conditions, excess levels of the excitotoxin glutamate

> > will convert to GABA. There seems to be a " disconnect " in this

> > process for autistic children so that the excitatory

> > neurotransmission is high (stims) and the calming neurotransmission

> > is low (lack of speech). When conditions occur that throw off this

> > delicate balance, then high levels of glutamate can accumulate while

> > the levels of GABA remain exceedingly low. This would create a

> > situation that would require decreasing the glutamate levels, and

> > increasing the GABA levels in order to restore balance. Chronic viral

> > infection may be related to this disconnect between glutamate and

> > GABA. "

> >

> > " Over seven years ago, Dr Blaylock described the pathway of

> > excitotoxin damage and the role it plays in neurological damage

> > brilliantly in his landmark book on excitotoxins. He spelled out

> > specifically how and why MSG, hydrolyzed vegetable protein, aspartame

> > and related compounds have been proven to cause death of neurons

> > beyond any reasonable doubt. More recently, this concept of

> > excitotoxin damage has been found to pertain to autism. Excitotoxins

> > are neurotransmitters such as glutamate or aspartate

> > that can excite the nerves to death when their levels are not

> > regulated properly. Foods or supplements that contain excitotoxins

> > include MSG, glutamic acid, glutamine, Nutra Sweet, aspartate,

> > aspartame and cysteine. Mercury and aluminum can trigger glutamate

> > release. Minimizing glutatmate is a differentiating factor in our

> > protocol and has helped many autistic children significantly. "

> >

>

>

> ------------------------------------------------------------------------

>

> No virus found in this incoming message.

> Checked by AVG Free Edition.

> Version: 7.5.488 / Virus Database: 269.13.30/1030 - Release Date: 25/09/2007

08:02

>

[Guest guest]

Thanks Sara, I'd wondered about this.

Margaret

> >

> > Hi Peta,

> >

> > Amy Yasko is really keen about reducing glutamates and

supplementing

> > a small amount of Gaba.

> >

> > As well as avoiding overly glutamate foods this also means NOT

> > supplementing L-gluatime or using alpha keto glutarates etc. I

> > can't find a good summary on-line - I'll paste what I could find

> > below. We were supplementing l-glutamine a lot before and were

slow

> > to reduce and then remove it - but Eddie's glutamine/gaba have

> > actually balanced out. So while we were supplementing he was low

and

> > when we stopped he improved. The more I learn the more I like

Yasko -

> > it is doing great things for Eddie.

> >

> > Best wishes,

> > Sandy

> >

> > http://forums. <http://forums.about.com/n/pfx/forum.aspx?>

> about.com/n/pfx/forum.aspx?

> > nav=printDiscussion & webtag=ab-autism & tid=4426

> > COPIED from this link ....

> > FYI, Here is some of what Dr Amy Yasko says about glutamate

in " The

> > Puzzle of Autism: Putting it all Together " : (pgs 8-9)

> >

> > " Glutamate is the main excitatory neurotransmitter in the body.

It is

> > essential for learning and for both short-term and long-term

memory.

> > It is also the precursor to the inhibitory neurotransmitter, GABA.

> > GABA is a calming neurotransmitter and is essential for speech.

GABA

> > neurons damp the propagation of sounds so that a distinction can

be

> > made between the onset of a sound and background noise....Problems

> > occur if the normal process of regulation of glutamate

malfunctions

> > and if toxic levels of this excitatory neurotransmitter build up

in

> > the synaptic junctions.

> > The balance between glutamate and GABA is like a seesaw. Under

normal

> > conditions, when the glutamate side gets too high, the GABA side

of

> > the seesaw will increase and decrease the glutamate. Under normal

> > functioning conditions, excess levels of the excitotoxin glutamate

> > will convert to GABA. There seems to be a " disconnect " in this

> > process for autistic children so that the excitatory

> > neurotransmission is high (stims) and the calming

neurotransmission

> > is low (lack of speech). When conditions occur that throw off this

> > delicate balance, then high levels of glutamate can accumulate

while

> > the levels of GABA remain exceedingly low. This would create a

> > situation that would require decreasing the glutamate levels, and

> > increasing the GABA levels in order to restore balance. Chronic

viral

> > infection may be related to this disconnect between glutamate and

> > GABA. "

> >

> > " Over seven years ago, Dr Blaylock described the pathway

of

> > excitotoxin damage and the role it plays in neurological damage

> > brilliantly in his landmark book on excitotoxins. He spelled out

> > specifically how and why MSG, hydrolyzed vegetable protein,

aspartame

> > and related compounds have been proven to cause death of neurons

> > beyond any reasonable doubt. More recently, this concept of

> > excitotoxin damage has been found to pertain to autism.

Excitotoxins

> > are neurotransmitters such as glutamate or aspartate

> > that can excite the nerves to death when their levels are not

> > regulated properly. Foods or supplements that contain excitotoxins

> > include MSG, glutamic acid, glutamine, Nutra Sweet, aspartate,

> > aspartame and cysteine. Mercury and aluminum can trigger glutamate

> > release. Minimizing glutatmate is a differentiating factor in our

> > protocol and has helped many autistic children significantly. "

> >

>

[Guest guest]

Thanks Sara, I'd wondered about this.

Margaret

> >

> > Hi Peta,

> >

> > Amy Yasko is really keen about reducing glutamates and

supplementing

> > a small amount of Gaba.

> >

> > As well as avoiding overly glutamate foods this also means NOT

> > supplementing L-gluatime or using alpha keto glutarates etc. I

> > can't find a good summary on-line - I'll paste what I could find

> > below. We were supplementing l-glutamine a lot before and were

slow

> > to reduce and then remove it - but Eddie's glutamine/gaba have

> > actually balanced out. So while we were supplementing he was low

and

> > when we stopped he improved. The more I learn the more I like

Yasko -

> > it is doing great things for Eddie.

> >

> > Best wishes,

> > Sandy

> >

> > http://forums. <http://forums.about.com/n/pfx/forum.aspx?>

> about.com/n/pfx/forum.aspx?

> > nav=printDiscussion & webtag=ab-autism & tid=4426

> > COPIED from this link ....

> > FYI, Here is some of what Dr Amy Yasko says about glutamate

in " The

> > Puzzle of Autism: Putting it all Together " : (pgs 8-9)

> >

> > " Glutamate is the main excitatory neurotransmitter in the body.

It is

> > essential for learning and for both short-term and long-term

memory.

> > It is also the precursor to the inhibitory neurotransmitter, GABA.

> > GABA is a calming neurotransmitter and is essential for speech.

GABA

> > neurons damp the propagation of sounds so that a distinction can

be

> > made between the onset of a sound and background noise....Problems

> > occur if the normal process of regulation of glutamate

malfunctions

> > and if toxic levels of this excitatory neurotransmitter build up

in

> > the synaptic junctions.

> > The balance between glutamate and GABA is like a seesaw. Under

normal

> > conditions, when the glutamate side gets too high, the GABA side

of

> > the seesaw will increase and decrease the glutamate. Under normal

> > functioning conditions, excess levels of the excitotoxin glutamate

> > will convert to GABA. There seems to be a " disconnect " in this

> > process for autistic children so that the excitatory

> > neurotransmission is high (stims) and the calming

neurotransmission

> > is low (lack of speech). When conditions occur that throw off this

> > delicate balance, then high levels of glutamate can accumulate

while

> > the levels of GABA remain exceedingly low. This would create a

> > situation that would require decreasing the glutamate levels, and

> > increasing the GABA levels in order to restore balance. Chronic

viral

> > infection may be related to this disconnect between glutamate and

> > GABA. "

> >

> > " Over seven years ago, Dr Blaylock described the pathway

of

> > excitotoxin damage and the role it plays in neurological damage

> > brilliantly in his landmark book on excitotoxins. He spelled out

> > specifically how and why MSG, hydrolyzed vegetable protein,

aspartame

> > and related compounds have been proven to cause death of neurons

> > beyond any reasonable doubt. More recently, this concept of

> > excitotoxin damage has been found to pertain to autism.

Excitotoxins

> > are neurotransmitters such as glutamate or aspartate

> > that can excite the nerves to death when their levels are not

> > regulated properly. Foods or supplements that contain excitotoxins

> > include MSG, glutamic acid, glutamine, Nutra Sweet, aspartate,

> > aspartame and cysteine. Mercury and aluminum can trigger glutamate

> > release. Minimizing glutatmate is a differentiating factor in our

> > protocol and has helped many autistic children significantly. "

> >

>

[Guest guest]

suggests that there might be more too it perhaps -- not very likely

that Dan doctors have a " basic lack understanding about the involved

chemistry " . They are after all doctors. More likely they disagree about

the involved chemistry and its likely operations. Denigrating one's

opponents while not explaining either point of view is rather

unimpressive, I think

Sally

mcollins2001uk wrote:

>

> Thanks Sara, I'd wondered about this.

> Margaret

>

>

> > >

> > > Hi Peta,

> > >

> > > Amy Yasko is really keen about reducing glutamates and

> supplementing

> > > a small amount of Gaba.

> > >

> > > As well as avoiding overly glutamate foods this also means NOT

> > > supplementing L-gluatime or using alpha keto glutarates etc. I

> > > can't find a good summary on-line - I'll paste what I could find

> > > below. We were supplementing l-glutamine a lot before and were

> slow

> > > to reduce and then remove it - but Eddie's glutamine/gaba have

> > > actually balanced out. So while we were supplementing he was low

> and

> > > when we stopped he improved. The more I learn the more I like

> Yasko -

> > > it is doing great things for Eddie.

> > >

> > > Best wishes,

> > > Sandy

> > >

> > > http://forums. <http://forums. about.com/ n/pfx/forum. aspx?

> <http://forums.about.com/n/pfx/forum.aspx?>>

> > about.com/n/ pfx/forum. aspx?

> > > nav=printDiscussion & webtag=ab- autism & tid= 4426

> > > COPIED from this link ....

> > > FYI, Here is some of what Dr Amy Yasko says about glutamate

> in " The

> > > Puzzle of Autism: Putting it all Together " : (pgs 8-9)

> > >

> > > " Glutamate is the main excitatory neurotransmitter in the body.

> It is

> > > essential for learning and for both short-term and long-term

> memory.

> > > It is also the precursor to the inhibitory neurotransmitter, GABA.

> > > GABA is a calming neurotransmitter and is essential for speech.

> GABA

> > > neurons damp the propagation of sounds so that a distinction can

> be

> > > made between the onset of a sound and background noise....Problems

> > > occur if the normal process of regulation of glutamate

> malfunctions

> > > and if toxic levels of this excitatory neurotransmitter build up

> in

> > > the synaptic junctions.

> > > The balance between glutamate and GABA is like a seesaw. Under

> normal

> > > conditions, when the glutamate side gets too high, the GABA side

> of

> > > the seesaw will increase and decrease the glutamate. Under normal

> > > functioning conditions, excess levels of the excitotoxin glutamate

> > > will convert to GABA. There seems to be a " disconnect " in this

> > > process for autistic children so that the excitatory

> > > neurotransmission is high (stims) and the calming

> neurotransmission

> > > is low (lack of speech). When conditions occur that throw off this

> > > delicate balance, then high levels of glutamate can accumulate

> while

> > > the levels of GABA remain exceedingly low. This would create a

> > > situation that would require decreasing the glutamate levels, and

> > > increasing the GABA levels in order to restore balance. Chronic

> viral

> > > infection may be related to this disconnect between glutamate and

> > > GABA. "

> > >

> > > " Over seven years ago, Dr Blaylock described the pathway

> of

> > > excitotoxin damage and the role it plays in neurological damage

> > > brilliantly in his landmark book on excitotoxins. He spelled out

> > > specifically how and why MSG, hydrolyzed vegetable protein,

> aspartame

> > > and related compounds have been proven to cause death of neurons

> > > beyond any reasonable doubt. More recently, this concept of

> > > excitotoxin damage has been found to pertain to autism.

> Excitotoxins

> > > are neurotransmitters such as glutamate or aspartate

> > > that can excite the nerves to death when their levels are not

> > > regulated properly. Foods or supplements that contain excitotoxins

> > > include MSG, glutamic acid, glutamine, Nutra Sweet, aspartate,

> > > aspartame and cysteine. Mercury and aluminum can trigger glutamate

> > > release. Minimizing glutatmate is a differentiating factor in our

> > > protocol and has helped many autistic children significantly. "

> > >

> >

>

>

> ------------------------------------------------------------------------

>

> No virus found in this incoming message.

> Checked by AVG Free Edition.

> Version: 7.5.488 / Virus Database: 269.13.30/1030 - Release Date: 25/09/2007

08:02

>

[Guest guest]

suggests that there might be more too it perhaps -- not very likely

that Dan doctors have a " basic lack understanding about the involved

chemistry " . They are after all doctors. More likely they disagree about

the involved chemistry and its likely operations. Denigrating one's

opponents while not explaining either point of view is rather

unimpressive, I think

Sally

mcollins2001uk wrote:

>

> Thanks Sara, I'd wondered about this.

> Margaret

>

>

> > >

> > > Hi Peta,

> > >

> > > Amy Yasko is really keen about reducing glutamates and

> supplementing

> > > a small amount of Gaba.

> > >

> > > As well as avoiding overly glutamate foods this also means NOT

> > > supplementing L-gluatime or using alpha keto glutarates etc. I

> > > can't find a good summary on-line - I'll paste what I could find

> > > below. We were supplementing l-glutamine a lot before and were

> slow

> > > to reduce and then remove it - but Eddie's glutamine/gaba have

> > > actually balanced out. So while we were supplementing he was low

> and

> > > when we stopped he improved. The more I learn the more I like

> Yasko -

> > > it is doing great things for Eddie.

> > >

> > > Best wishes,

> > > Sandy

> > >

> > > http://forums. <http://forums. about.com/ n/pfx/forum. aspx?

> <http://forums.about.com/n/pfx/forum.aspx?>>

> > about.com/n/ pfx/forum. aspx?

> > > nav=printDiscussion & webtag=ab- autism & tid= 4426

> > > COPIED from this link ....

> > > FYI, Here is some of what Dr Amy Yasko says about glutamate

> in " The

> > > Puzzle of Autism: Putting it all Together " : (pgs 8-9)

> > >

> > > " Glutamate is the main excitatory neurotransmitter in the body.

> It is

> > > essential for learning and for both short-term and long-term

> memory.

> > > It is also the precursor to the inhibitory neurotransmitter, GABA.

> > > GABA is a calming neurotransmitter and is essential for speech.

> GABA

> > > neurons damp the propagation of sounds so that a distinction can

> be

> > > made between the onset of a sound and background noise....Problems

> > > occur if the normal process of regulation of glutamate

> malfunctions

> > > and if toxic levels of this excitatory neurotransmitter build up

> in

> > > the synaptic junctions.

> > > The balance between glutamate and GABA is like a seesaw. Under

> normal

> > > conditions, when the glutamate side gets too high, the GABA side

> of

> > > the seesaw will increase and decrease the glutamate. Under normal

> > > functioning conditions, excess levels of the excitotoxin glutamate

> > > will convert to GABA. There seems to be a " disconnect " in this

> > > process for autistic children so that the excitatory

> > > neurotransmission is high (stims) and the calming

> neurotransmission

> > > is low (lack of speech). When conditions occur that throw off this

> > > delicate balance, then high levels of glutamate can accumulate

> while

> > > the levels of GABA remain exceedingly low. This would create a

> > > situation that would require decreasing the glutamate levels, and

> > > increasing the GABA levels in order to restore balance. Chronic

> viral

> > > infection may be related to this disconnect between glutamate and

> > > GABA. "

> > >

> > > " Over seven years ago, Dr Blaylock described the pathway

> of

> > > excitotoxin damage and the role it plays in neurological damage

> > > brilliantly in his landmark book on excitotoxins. He spelled out

> > > specifically how and why MSG, hydrolyzed vegetable protein,

> aspartame

> > > and related compounds have been proven to cause death of neurons

> > > beyond any reasonable doubt. More recently, this concept of

> > > excitotoxin damage has been found to pertain to autism.

> Excitotoxins

> > > are neurotransmitters such as glutamate or aspartate

> > > that can excite the nerves to death when their levels are not

> > > regulated properly. Foods or supplements that contain excitotoxins

> > > include MSG, glutamic acid, glutamine, Nutra Sweet, aspartate,

> > > aspartame and cysteine. Mercury and aluminum can trigger glutamate

> > > release. Minimizing glutatmate is a differentiating factor in our

> > > protocol and has helped many autistic children significantly. "

> > >

> >

>

>

> ------------------------------------------------------------------------

>

> No virus found in this incoming message.

> Checked by AVG Free Edition.

> Version: 7.5.488 / Virus Database: 269.13.30/1030 - Release Date: 25/09/2007

08:02

>

[Guest guest]

Good point Sally. I wonder if Yasko does explain it somewhere?

Does anyone have her explanation of the DAN interpretation of the

chemistry involved?

Zoe

> > > >

> > > > Hi Peta,

> > > >

> > > > Amy Yasko is really keen about reducing glutamates and

> > supplementing

> > > > a small amount of Gaba.

> > > >

> > > > As well as avoiding overly glutamate foods this also means

NOT

> > > > supplementing L-gluatime or using alpha keto glutarates etc.

I

> > > > can't find a good summary on-line - I'll paste what I could

find

> > > > below. We were supplementing l-glutamine a lot before and

were

> > slow

> > > > to reduce and then remove it - but Eddie's glutamine/gaba

have

> > > > actually balanced out. So while we were supplementing he was

low

> > and

> > > > when we stopped he improved. The more I learn the more I like

> > Yasko -

> > > > it is doing great things for Eddie.

> > > >

> > > > Best wishes,

> > > > Sandy

> > > >

> > > > http://forums. <http://forums. about.com/ n/pfx/forum. aspx?

> > <http://forums.about.com/n/pfx/forum.aspx?>>

> > > about.com/n/ pfx/forum. aspx?

> > > > nav=printDiscussion & webtag=ab- autism & tid= 4426

> > > > COPIED from this link ....

> > > > FYI, Here is some of what Dr Amy Yasko says about glutamate

> > in " The

> > > > Puzzle of Autism: Putting it all Together " : (pgs 8-9)

> > > >

> > > > " Glutamate is the main excitatory neurotransmitter in the

body.

> > It is

> > > > essential for learning and for both short-term and long-term

> > memory.

> > > > It is also the precursor to the inhibitory neurotransmitter,

GABA.

> > > > GABA is a calming neurotransmitter and is essential for

speech.

> > GABA

> > > > neurons damp the propagation of sounds so that a distinction

can

> > be

> > > > made between the onset of a sound and background

noise....Problems

> > > > occur if the normal process of regulation of glutamate

> > malfunctions

> > > > and if toxic levels of this excitatory neurotransmitter

build up

> > in

> > > > the synaptic junctions.

> > > > The balance between glutamate and GABA is like a seesaw.

Under

> > normal

> > > > conditions, when the glutamate side gets too high, the GABA

side

> > of

> > > > the seesaw will increase and decrease the glutamate. Under

normal

> > > > functioning conditions, excess levels of the excitotoxin

glutamate

> > > > will convert to GABA. There seems to be a " disconnect " in

this

> > > > process for autistic children so that the excitatory

> > > > neurotransmission is high (stims) and the calming

> > neurotransmission

> > > > is low (lack of speech). When conditions occur that throw

off this

> > > > delicate balance, then high levels of glutamate can

accumulate

> > while

> > > > the levels of GABA remain exceedingly low. This would create

a

> > > > situation that would require decreasing the glutamate

levels, and

> > > > increasing the GABA levels in order to restore balance.

Chronic

> > viral

> > > > infection may be related to this disconnect between

glutamate and

> > > > GABA. "

> > > >

> > > > " Over seven years ago, Dr Blaylock described the

pathway

> > of

> > > > excitotoxin damage and the role it plays in neurological

damage

> > > > brilliantly in his landmark book on excitotoxins. He spelled

out

> > > > specifically how and why MSG, hydrolyzed vegetable protein,

> > aspartame

> > > > and related compounds have been proven to cause death of

neurons

> > > > beyond any reasonable doubt. More recently, this concept of

> > > > excitotoxin damage has been found to pertain to autism.

> > Excitotoxins

> > > > are neurotransmitters such as glutamate or aspartate

> > > > that can excite the nerves to death when their levels are not

> > > > regulated properly. Foods or supplements that contain

excitotoxins

> > > > include MSG, glutamic acid, glutamine, Nutra Sweet,

aspartate,

> > > > aspartame and cysteine. Mercury and aluminum can trigger

glutamate

> > > > release. Minimizing glutatmate is a differentiating factor

in our

> > > > protocol and has helped many autistic children

significantly. "

> > > >

> > >

> >

> >

> > -----------------------------------------------------------------

-------

> >

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Date: 25/09/2007 08:02

> >

>

[Guest guest]

L Glutamine was one of the better supplements we used with .

It was reccomended to me here yonks ago and alongside enzymes really contributed to his gut healing, he did fantastically well for yrs, didn't use it as an all the time thing but certainly helped in settling things down at the start.

Didn't see any behaviours from using it, if anything his behaviour imporved considerably from being free of pain.

For behaviours almost always come with a gut problem.

There doesn't seem to be a hard and fast rule with much of this, or certainly not with my kid, since re-introducing Vit D his bowels are slowly getting better, Why?

I'm hoping to figure this all out before he is collecting his pension. I'm not keen on any Dr or nutritionist saying something is an absolute, in as much as must do a certain diet or won't use a certain supplement across the board for every child. Just my very non scientific observations.

Vicky

[Guest guest]

Hi Mandi

Interested to know what they say and who says it??

Zoe

>

> You should hear what DAN's say about Yasko...............and

Yasko 'absorbs'

> scientific studies on a daily basis, not that I think she has

everything

> right

>

> Mandi x

>