Re: Re: Neuropathy

[Guest guest]

Yeah and what I do not get is the fact I feel like I have high blood pressure when eating higher salt but it shows normal or only slightly elevated. I mean I'm having strong pounding heartbeat, extreme chest pressure, short of breath,etc.

Re: Neuropathy

Yes I get tremors, usually only on the right side. They can get quite severe at times. > > > >> > > > Many have pains cramps in hands legs and feet. Tell us more about > > > the> > > > neuropathy please. BS K been low?> > > >> > > > Tiped sad Send form mi> > > > iPhone ;-)> > > >> > > > May your pressure be low!> > > >> > > > CE Grim MD> > > > Specializing in Difficult> > > > Hypertension> > > >> > > > On Mar 21, 2010, at 4:54 PM, Zhen C

[Guest guest]

It sounds like you have autonomic neuropathy with sympathetic excess. I'm looking for a relationship to Conn's with autonomic dysfunction. I think that with fluids overload, the nervous system performs poorly at managing blood pressure through postural changes etc. Were you anxious the whole time you were painting? You need to avoid the cigarettes. They damage the vascular sensitivity to vasodilators such as NO. The resulting endothelial dysfunction causes hypertension, erectile dysfunction, and coronary artery disease. To: hyperaldosteronism Sent: Fri, March 26, 2010 6:29:00 PMSubject: Re: Re: Neuropathy

First time was : 140/80 PULSE:110Yes, what I don't understand is I checked it again 1/2 hour after the above and bp was:150/76 PULSE: 89I know I sound stupid doing this but: I then tried having a square of chocolate, (to see what my bp was when I had the hard heart pounding)I'd also had cigarette, after I'd eaten chocolate, straight away could feel heart pounding fast and hard. Checked my bp and it was:113/70 PULSE: 107 ?? Why has it changed so much, don't get it. This morning I hadn't had anything wrong, was painting my lounge, kept getting very hot flushes, sweating, fast heart rate and headache, which got worse when I was stretching arm up to paint the top of the walls. Sent using BlackBerry® from OrangeFrom: " Stone" <astone312@suddenlin k.net>

Date: Fri, 26 Mar 2010 17:13:52 -0500To: <hyperaldosteronism@ yahoogroups. com>Subject: Re: [hyperaldosteronism ] Re: Neuropathy

you said after eating you felt your back ache.....I just finished salt loading and now my back is worse too in the same tender spot in left mid back. That is weird.

[hyperaldosteronism ] Re: Neuropathy

Yes I get tremors, usually only on the right side. They can get quite severe at times. > > > >> > > > Many have pains cramps in hands legs and feet. Tell us more about > > > the> > > > neuropathy please. BS K been low?> > > >> > > > Tiped sad Send form mi> > > > iPhone ;-)> > > >> > > > May your pressure be low!> > > >> > > > CE Grim MD> > > > Specializing in Difficult> > > > Hypertension> > > >> > > > On Mar 21, 2010, at 4:54 PM, Zhen C

[Guest guest]

Yes, well I thought chocolate was the worst for me as like you I have those horrible scary symptoms, when my heart rate is elevated but bp low normal.What else are you eating? To get your salt? Its also important to avoid fat on dash so that must contribute to the symptoms combined with salt? Are you eating anything high fat like cheese? Pheo's react to cheese, soy, beer, avacardos, bananas, yeast, cured meats, coffee, tea,chocolate and other tyraine foods...but without the chocolate my bp was high but pulse a bit lower. Maybe its to do with stimulants raising metabolism caffine or tyraine..god knows..!!I know if I just sat here and drank water I'd swell up and I would really ruff... very high, ears ring etc etc Sent using BlackBerry® from OrangeDate: Fri, 26 Mar 2010 17:46:49 -0500To: <hyperaldosteronism >Subject: Re: Re: Neuropathy Yeah and what I do not get is the fact I feel like I have high blood pressure when eating higher salt but it shows normal or only slightly elevated. I mean I'm having strong pounding heartbeat, extreme chest pressure, short of breath,etc. Re: Neuropathy Yes I get tremors, usually only on the right side. They can get quite severe at times. > > > >> > > > Many have pains cramps in hands legs and feet. Tell us more about > > > the> > > > neuropathy please. BS K been low?> > > >> > > > Tiped sad Send form mi> > > > iPhone ;-)> > > >> > > > May your pressure be low!> > > >> > > > CE Grim MD> > > > Specializing in Difficult> > > > Hypertension> > > >> > > > On Mar 21, 2010, at 4:54 PM, Zhen C

[Guest guest]

I know smoking is so stupid but iam giving up whilst in hospital next week. Its been such a fight to get there and follow strict diet, I couldn't do it all at once.I don't smoke a lot.No, not the whole time I painted from 8.30am til 1pm but the firs 2 hours I got very hot, headache, anxious, flushed took. Top off so hot left vest on then got cold put it back on...I wonder if it was when I was reaching up as I have a spasm in my neck and it was going tight and causing problems (I've just stuck to the main bulk of walls, I can reach up..I always swell up in hot shower too or bath..a bit strange!?!Sent using BlackBerry® from OrangeDate: Fri, 26 Mar 2010 15:59:32 -0700 (PDT)To: <hyperaldosteronism >Subject: Re: Re: Neuropathy It sounds like you have autonomic neuropathy with sympathetic excess. I'm looking for a relationship to Conn's with autonomic dysfunction. I think that with fluids overload, the nervous system performs poorly at managing blood pressure through postural changes etc. Were you anxious the whole time you were painting? You need to avoid the cigarettes. They damage the vascular sensitivity to vasodilators such as NO. The resulting endothelial dysfunction causes hypertension, erectile dysfunction, and coronary artery disease. From: "moseleymandhotmail (DOT) co.uk" <moseleymandhotmail (DOT) co.uk>To: hyperaldosteronism Sent: Fri, March 26, 2010 6:29:00 PMSubject: Re: Re: Neuropathy First time was : 140/80 PULSE:110Yes, what I don't understand is I checked it again 1/2 hour after the above and bp was:150/76 PULSE: 89I know I sound stupid doing this but: I then tried having a square of chocolate, (to see what my bp was when I had the hard heart pounding)I'd also had cigarette, after I'd eaten chocolate, straight away could feel heart pounding fast and hard. Checked my bp and it was:113/70 PULSE: 107 ?? Why has it changed so much, don't get it. This morning I hadn't had anything wrong, was painting my lounge, kept getting very hot flushes, sweating, fast heart rate and headache, which got worse when I was stretching arm up to paint the top of the walls. Sent using BlackBerry® from OrangeFrom: " Stone" <astone312@suddenlin k.net>Date: Fri, 26 Mar 2010 17:13:52 -0500To: <hyperaldosteronism@ yahoogroups. com>Subject: Re: [hyperaldosteronism ] Re: Neuropathy you said after eating you felt your back ache.....I just finished salt loading and now my back is worse too in the same tender spot in left mid back. That is weird. [hyperaldosteronism ] Re: Neuropathy Yes I get tremors, usually only on the right side. They can get quite severe at times. > > > >> > > > Many have pains cramps in hands legs and feet. Tell us more about > > > the> > > > neuropathy please. BS K been low?> > > >> > > > Tiped sad Send form mi> > > > iPhone ;-)> > > >> > > > May your pressure be low!> > > >> > > > CE Grim MD> > > > Specializing in Difficult> > > > Hypertension> > > >> > > > On Mar 21, 2010, at 4:54 PM, Zhen C

[Guest guest]

I went very tiered suddenly aswell, moody, row with my sister over nothing...I did do a lot of painting but I felt fatigued painting isn't that strenuous is it..Sent using BlackBerry® from OrangeDate: Fri, 26 Mar 2010 15:59:32 -0700 (PDT)To: <hyperaldosteronism >Subject: Re: Re: Neuropathy It sounds like you have autonomic neuropathy with sympathetic excess. I'm looking for a relationship to Conn's with autonomic dysfunction. I think that with fluids overload, the nervous system performs poorly at managing blood pressure through postural changes etc. Were you anxious the whole time you were painting? You need to avoid the cigarettes. They damage the vascular sensitivity to vasodilators such as NO. The resulting endothelial dysfunction causes hypertension, erectile dysfunction, and coronary artery disease. From: "moseleymandhotmail (DOT) co.uk" <moseleymandhotmail (DOT) co.uk>To: hyperaldosteronism Sent: Fri, March 26, 2010 6:29:00 PMSubject: Re: Re: Neuropathy First time was : 140/80 PULSE:110Yes, what I don't understand is I checked it again 1/2 hour after the above and bp was:150/76 PULSE: 89I know I sound stupid doing this but: I then tried having a square of chocolate, (to see what my bp was when I had the hard heart pounding)I'd also had cigarette, after I'd eaten chocolate, straight away could feel heart pounding fast and hard. Checked my bp and it was:113/70 PULSE: 107 ?? Why has it changed so much, don't get it. This morning I hadn't had anything wrong, was painting my lounge, kept getting very hot flushes, sweating, fast heart rate and headache, which got worse when I was stretching arm up to paint the top of the walls. Sent using BlackBerry® from OrangeFrom: " Stone" <astone312@suddenlin k.net>Date: Fri, 26 Mar 2010 17:13:52 -0500To: <hyperaldosteronism@ yahoogroups. com>Subject: Re: [hyperaldosteronism ] Re: Neuropathy you said after eating you felt your back ache.....I just finished salt loading and now my back is worse too in the same tender spot in left mid back. That is weird. [hyperaldosteronism ] Re: Neuropathy Yes I get tremors, usually only on the right side. They can get quite severe at times. > > > >> > > > Many have pains cramps in hands legs and feet. Tell us more about > > > the> > > > neuropathy please. BS K been low?> > > >> > > > Tiped sad Send form mi> > > > iPhone ;-)> > > >> > > > May your pressure be low!> > > >> > > > CE Grim MD> > > > Specializing in Difficult> > > > Hypertension> > > >> > > > On Mar 21, 2010, at 4:54 PM, Zhen C

[Guest guest]

Guess you could try a cig and choc every 4-6 hours to see the longer term effect for let us know what happens. In gen smoking increases BP AND brings on heart attack and stroke 20 years sooner. MAybe choc will counteract the smoking but I would mot bet your life on it. Tiped sad Send form miiPhone ;-)May your pressure be low!CE Grim MDSpecializing in DifficultHypertension

First time was : 140/80 PULSE:110Yes, what I don't understand is I checked it again 1/2 hour after the above and bp was:150/76 PULSE: 89I know I sound stupid doing this but: I then tried having a square of chocolate, (to see what my bp was when I had the hard heart pounding)I'd also had cigarette, after I'd eaten chocolate, straight away could feel heart pounding fast and hard. Checked my bp and it was:113/70 PULSE: 107 ?? Why has it changed so much, don't get it. This morning I hadn't had anything wrong, was painting my lounge, kept getting very hot flushes, sweating, fast heart rate and headache, which got worse when I was stretching arm up to paint the top of the walls. Sent using BlackBerry® from OrangeFrom: " Stone" <astone312suddenlink (DOT) net>

Date: Fri, 26 Mar 2010 17:13:52 -0500To: <hyperaldosteronism >Subject: Re: Re: Neuropathy

you said after eating you felt your back ache.....I just finished salt loading and now my back is worse too in the same tender spot in left mid back. That is weird.

Re: Neuropathy

Yes I get tremors, usually only on the right side. They can get quite severe at times. >> When I had my worst attack, after going on prozac one day. > > I'd also given up on my diet (eating chocolate biscuits and drinking coffee) along with sudden shock of my sister being beaten up..> > I think the prozac had a bad affect on me, my skin was very itchy, my jaw was locking and felt lie I was going into a dark tunnel...> > The night after I took

[Guest guest]

You only swell if you drink water AND eat too much salt for your body. How much is too much? Enough to make BP GOEUP and body swell. Tiped sad Send form miiPhone ;-)May your pressure be low!CE Grim MDSpecializing in DifficultHypertension

Yes, well I thought chocolate was the worst for me as like you I have those horrible scary symptoms, when my heart rate is elevated but bp low normal.What else are you eating? To get your salt? Its also important to avoid fat on dash so that must contribute to the symptoms combined with salt? Are you eating anything high fat like cheese? Pheo's react to cheese, soy, beer, avacardos, bananas, yeast, cured meats, coffee, tea,chocolate and other tyraine foods...but without the chocolate my bp was high but pulse a bit lower. Maybe its to do with stimulants raising metabolism caffine or tyraine..god knows..!!I know if I just sat here and drank water I'd swell up and I would really ruff... very high, ears ring etc etc Sent using BlackBerry® from OrangeFrom: " Stone" <astone312suddenlink (DOT) net>

Date: Fri, 26 Mar 2010 17:46:49 -0500To: <hyperaldosteronism >Subject: Re: Re: Neuropathy

Yeah and what I do not get is the fact I feel like I have high blood pressure when eating higher salt but it shows normal or only slightly elevated. I mean I'm having strong pounding heartbeat, extreme chest pressure, short of breath,etc.

Re: Re: Neuropathy

Not your thyroid would be both hands more likely.

CE Grim MD

[Guest guest]

That is the reason I ask my patients to write down what the Bp is before the measire it and then measure it. They find out they cannot tell by the way they feel. Tiped sad Send form miiPhone ;-)May your pressure be low!CE Grim MDSpecializing in DifficultHypertension

Yeah and what I do not get is the fact I feel like I have high blood pressure when eating higher salt but it shows normal or only slightly elevated. I mean I'm having strong pounding heartbeat, extreme chest pressure, short of breath,etc.

Re: Neuropathy

Yes I get tremors, usually only on the right side. They can get quite severe at times. >> When I had my worst attack, after going on prozac one day. > > I'd also given up on my diet (eating chocolate biscuits and drinking coffee) along with sudden shock of my sister being beaten up..> > I think the prozac had a bad affect on me, my skin was very itchy, my jaw was locking and felt lie I was going into a dark tunnel...> > The night after I took prozac, I jumped up in the night 3am my heart was beating hard avery fast, my head felt like it was going to explode with headache, I was manic, my face, neck, arm leg went into spasm,> My bp was 145/90 (went to a and e)> > After this event ..I was very pale, skin was clamy and strange feeling, I was just laying starring in a trance at home. continued to tremble for a week, had dioreah for a week, had lost 1/2 a stone instantly, couldn't smoke my heart would pound so much, was jumping up every time I tried to sleep, gasping for air.> > This was all after giving up on diet and trying take prozac and stress.> > Has anyone else suffered trembling hands....with like a buzz going through body?> > This also sounds like a Pheochromocytoma from what I've been reading. So. I just wondered if any one has trembling hands from PA.> > I was still working for the nhs, went into to see my boss and couldn't hold a pen for my hands shaking so much..> > > > Sent using BlackBerry® from Orange> > -----Original Message-----> > Date: Tue, 23 Mar 2010 00:31:41 > To: <hyperaldosteronism >>

[Guest guest]

You can always be comforted by the fact that smoking cures lung cancer. It dies when you do. Tiped sad Send form miiPhone ;-)May your pressure be low!CE Grim MDSpecializing in DifficultHypertension

I know smoking is so stupid but iam giving up whilst in hospital next week. Its been such a fight to get there and follow strict diet, I couldn't do it all at once.I don't smoke a lot.No, not the whole time I painted from 8.30am til 1pm but the firs 2 hours I got very hot, headache, anxious, flushed took. Top off so hot left vest on then got cold put it back on...I wonder if it was when I was reaching up as I have a spasm in my neck and it was going tight and causing problems (I've just stuck to the main bulk of walls, I can reach up..I always swell up in hot shower too or bath..a bit strange!?!Sent using BlackBerry® from OrangeFrom: Zhen Chu <zhenchuymail>

Date: Fri, 26 Mar 2010 15:59:32 -0700 (PDT)To: <hyperaldosteronism >Subject: Re: Re: Neuropathy

It sounds like you have autonomic neuropathy with sympathetic excess. I'm looking for a relationship to Conn's with autonomic dysfunction. I think that with fluids overload, the nervous system performs poorly at managing blood pressure through postural changes etc. Were you anxious the whole time you were painting? You need to avoid the cigarettes. They damage the vascular sensitivity to vasodilators such as NO. The resulting endothelial dysfunction causes hypertension, erectile dysfunction, and coronary artery disease. From: "moseleymandhotmail (DOT) co.uk" <moseleymandhotmail (DOT) co.uk>To: hyperaldosteronism Sent: Fri, March 26, 2010 6:29:00 PMSubject: Re: Re: Neuropathy

First time was : 140/80 PULSE:110Yes, what I don't understand is I checked it again 1/2 hour after the above and bp was:150/76 PULSE: 89I know I sound stupid doing this but: I then tried having a square of chocolate, (to see what my bp was when I had the hard heart pounding)I'd also had cigarette, after I'd eaten chocolate, straight away could feel heart pounding fast and hard. Checked my bp and it was:113/70 PULSE: 107 ?? Why has it changed so much, don't get it. This morning I hadn't had anything wrong, was painting my lounge, kept getting very hot flushes, sweating, fast heart rate and headache, which got worse when I was stretching arm up to paint the top of the walls. Sent using BlackBerry® from OrangeFrom: " Stone" <astone312@suddenlin k.net>

Date: Fri, 26 Mar 2010 17:13:52 -0500To: <hyperaldosteronism@ yahoogroups. com>Subject: Re: [hyperaldosteronism ] Re: Neuropathy

you said after eating you felt your back ache.....I just finished salt loading and now my back is worse too in the same tender spot in left mid back. That is weird.

Re: [hyperaldosteronism ] Re: Neuropathy

Not your thyroid would be both hands more likely.

CE Grim MD

[Guest guest]

Don't recommend wrist bands unless uless arm is thigh siZe. Have ur dr validate it on you. Be sure to keep it at heart level. 140/80 would be an unuSual BP WOTH AN AN AUTO DEVICE BOTH END IN ZERO. THIS should only happen about 1 in 100 readings. Tiped sad Send form miiPhone ;-)May your pressure be low!CE Grim MDSpecializing in DifficultHypertension

Dr.grim I was really stupid and had a sandwich, packet of crisps as in such a rush and was starvingMy bp is 140/80 and pulse 109And I ve just started feeling fast heart, anxious,backs acheing, mouth very dry, clenching jaw but not as bad as I have at other times!! I've just got a proper bp wrist band to keep an eye on bp. Sent using BlackBerry® from OrangeFrom: Clarence Grim <lowerbp2mac>

Date: Fri, 26 Mar 2010 11:13:31 -0500To: <hyperaldosteronism >Subject: Re: Re: Neuropathy

but the last one you stated was 2.94. Please go to a Yahoo or other thyroid group for these questions. Not in our area of expertise.CE Grim MDOn Mar 26, 2010, at 9:29 AM, moseleymandhotmail (DOT) co.uk wrote:I thought 0.68 was low? Along with low T4 and under T3Why would myt T3 be so low all the time? The diet I've been doing?Sent using BlackBerry® from OrangeFrom: Clarence Grim <lowerbp2mac>Date: Fri, 26 Mar 2010 08:56:30 -0500To: hyperaldosteronism <hyperaldosteronism >Subject: Re: Re: Neuropathy Looks good. Tiped sad Send form miiPhone ;-)May your pressure be low!CE Grim MDSpecializing in DifficultHypertensionOn Mar 26, 2010, at 8:47 AM, moseleymandhotmail (DOT) co.uk wrote: My tsh is always the same: 0.68(aslong as: I'm eating normal,no smoking no caffine)T3 3.5. (4-6.?)T4 13.2 - (12-22)Tested once on my low carb diet diet, just after smoked and drunk gallons of coffee TSH 2.94T4 13.4 :)Sent using BlackBerry® from OrangeFrom: Clarence Grim <lowerbp2mac>Date: Fri, 26 Mar 2010 08:23:11 -0500To: hyperaldosteronism <hyperaldosteronism >Subject: Re: Re: Neuropathy What has your TSH BEEN NTiped sad Send form miiPhone ;-)May your pressure be low!CE Grim MDSpecializing in DifficultHypertensionOn Mar 26, 2010, at 1:58 AM, moseleymandhotmail (DOT) co.uk wrote: I get tremor in both handsSent using BlackBerry® from OrangeFrom: Clarence Grim <lowerbp2mac>Date: Thu, 25 Mar 2010 19:18:16 -0500To: <hyperaldosteronism >Subject: Re: Re: Neuropathy Not your thyroid would be both hands more likely.CE Grim MDI also have had a slight trmor in my left hand on and off. I haven't had one in awhile though. I just got diagnosed as havy autoimmune thyroid so I was thinkin it could possibly be when my thyroid is going from hypo to hyper...I think I have gone back and forth. The hand also feels weaker when have the tremor. Re: Neuropathy> > Many years ago, they ran a nerve conduction velocity test and it was "normal". The NCV test doesn't check fine fiber nerves though. It's a barbaric test where they pass a knitting needle through your muscle and then tell you to flex the muscle. Ouch! They learned nothing. A nerve biopsy may have been helpful, but somehow that doc never remembered to arrange it. Other testing, such as tilt table, quantitative sensory testing, autonomic nerve sensory testing, thermography and ANSAR test shows important deficits for certain fine fiber nerves and impaired autonomic nerve function. Other fine fiber nerves were okay. So, I was just wondering if others experienced neuropathic pain or autonomic neuropathy related to PA. I noted that quite a few here have reported orthostatic intolerance, intolerance to heat and other symptoms of impaired autonomic function. There are some who write of full recovery from the surgical removal. > > Getting someone to do a blood draw carefully to get a good K wil

[Guest guest]

I can eat anything as long as salt intake is under about 325 mg a meal because over that is when I start feeling worse symptoms. I have stayed away from caffeine though too because anything that increases my pulse also makes me feel worse. I try to keep my heart as calm as possible to stop from feeling yucky...this includes exercise. I only occasionally walk my dog when feel well. I have tried to do more but feeling is uncomfortable and get easily tired.

Re: Neuropathy

Yes I get tremors, usually only on the right side. They can get quite severe at times. > > > >> > > > Many have pains cramps in hands legs and feet. Tell us more about > > > the> > > > neuropathy please. BS K been low?> > > >> > > > Tiped sad Send form mi> > > > iPhone ;-)> > > >> > > > May your pressure be low!> > > >> > > > CE Grim MD> > > > Specializing in Difficult> > > > Hypertension> > > >> > > > On Mar 21, 2010, at 4:54 PM, Zhen C

[Guest guest]

We suspect that low K may interact with the autonomic system.CE Grim MDCan you elaborate on autonomic neuropathy with sympathetic excess? I googled a bit, find much on autonomic neuropathy related to diabetes which I do not have.. not much on the sympathetic excess relationship.I had a 48 hr BP monitor in 2008 which showed that my BP dropped to my normal of 90/60 while asleep; up to 135/85ish pretty much as soon as I got up out of bed. That was two years ago so don't know if it is the same now. At that time aldo was normal and renin low; Jan '10 results show aldo high and renin normal but I was on ACE and BB then so endo wanted to repeat. I had repeat aldo/renin this week, no results yet.> >>>>>>> > > >> >>>>>>> > >>>>>> > > > Many have pains cramps in hands legs and feet. Tell > >>>>>> us more about > >>>>>>> > >>>>>> > > the> >>>>>>> > > > neuropathy please. BS K been > >>>>>> low?> >>>>>>> > > >> >>>>>>> > > > Tiped sad Send > >>>>>> form mi> >>>>>>> > > > iPhone ;-)> >>>>>>> > > > >>>>>> >> >>>>>>> > > > May your pressure be low!> >>>>>>> > > >>>>>> > >> >>>>>>> > > > CE Grim MD> >>>>>>> > > > > >>>>>> Specializing in Difficult> >>>>>>> > > > > >>>>>> Hypertension> >>>>>>> > > >> >>>>>>> > > > On Mar > >>>>>> 21, 2010, at 4:54 PM, Zhen > >>>>>> C> >>> >>> >>> >>> >>

[Guest guest]

Kim my Aldo was high and renin normal the first time I tested. I was on ace inhibitor also. After 2 weeks on verapamil I was retested and ny renin was low. I have since done the saline suppression test, ct and next week will have the AVS.Best wishes to u!Sent from my iPod

We suspect that low K may interact with the autonomic system.CE Grim MDCan you elaborate on autonomic neuropathy with sympathetic excess? I googled a bit, find much on autonomic neuropathy related to diabetes which I do not have.. not much on the sympathetic excess relationship.I had a 48 hr BP monitor in 2008 which showed that my BP

dropped to my normal of 90/60 while asleep; up to 135/85ish pretty much as soon as I got up out of bed. That was two years ago so don't know if it is the same now. At that time aldo was normal and renin low; Jan '10 results show aldo high and renin normal but I was on ACE and BB then so endo wanted to repeat. I had repeat aldo/renin this week, no results yet.> >>>>>>> > > >> >>>>>>> > >>>>>> > > > Many have pains cramps in hands legs and feet. Tell > >>>>>> us more about > >>>>>>> > >>>>>> > > the> >>>>>>> > > > neuropathy please. BS K been > >>>>>> low?> >>>>>>> > > >> >>>>>>> > > > Tiped sad Send > >>>>>> form mi> >>>>>>> > > > iPhone ;-)> >>>>>>> > > > >>>>>> >> >>>>>>> > > > May your pressure be low!> >>>>>>> > > >>>>>> > >> >>>>>>> > > > CE Grim MD>

>>>>>>> > > > > >>>>>> Specializing in Difficult> >>>>>>> > > > > >>>>>> Hypertension> >>>>>>> > > >> >>>>>>> > > > On Mar > >>>>>> 21, 2010, at 4:54 PM, Zhen > >>>>>> C> >>> >>> >>> >>> >>

[Guest guest]

Can someone do a PUBMED search on hypokalemia and autonomic function.As JW notes I would abandon googling for health problems and questions where you get millions of "finds" many of the ones that turn up at the top get there because the paid to get there and do a pubmed search instead.JW now that I think of this it is excellent advice. I will add to our welcome. CE Grim MDKim my Aldo was high and renin normal the first time I tested. I was on ace inhibitor also. After 2 weeks on verapamil I was retested and ny renin was low. I have since done the saline suppression test, ct and next week will have the AVS.Best wishes to u!Sent from my iPodOn Mar 27, 2010, at 2:16 PM, Clarence Grim <lowerbp2mac> wrote: We suspect that low K may interact with the autonomic system.CE Grim MDCan you elaborate on autonomic neuropathy with sympathetic excess? I googled a bit, find much on autonomic neuropathy related to diabetes which I do not have.. not much on the sympathetic excess relationship.I had a 48 hr BP monitor in 2008 which showed that my BP dropped to my normal of 90/60 while asleep; up to 135/85ish pretty much as soon as I got up out of bed. That was two years ago so don't know if it is the same now. At that time aldo was normal and renin low; Jan '10 results show aldo high and renin normal but I was on ACE and BB then so endo wanted to repeat. I had repeat aldo/renin this week, no results yet.> >>>>>>> > > >> >>>>>>> > >>>>>> > > > Many have pains cramps in hands legs and feet. Tell > >>>>>> us more about > >>>>>>> > >>>>>> > > the> >>>>>>> > > > neuropathy please. BS K been > >>>>>> low?> >>>>>>> > > >> >>>>>>> > > > Tiped sad Send > >>>>>> form mi> >>>>>>> > > > iPhone ;-)> >>>>>>> > > > >>>>>> >> >>>>>>> > > > May your pressure be low!> >>>>>>> > > >>>>>> > >> >>>>>>> > > > CE Grim MD> >>>>>>> > > > > >>>>>> Specializing in Difficult> >>>>>>> > > > > >>>>>> Hypertension> >>>>>>> > > >> >>>>>>> > > > On Mar > >>>>>> 21, 2010, at 4:54 PM, Zhen > >>>>>> C> >>> >>> >>> >>> >>

[Guest guest]

I'm still trying to find answers to this question. At one point in my illness, they did a tilt table and BP went up when changing from horizontal to vertical position. Normal would be a minimal drop and orthostatic hypotension would present with a drop in BP with head up. There is a nice collection of articles on www.ans-hrv.com concerning autonomic testing and treatment. The arteries and heart have stretch receptors that monitor blood pressure. These signal the autonomic nervous system through the vagus nerve. An illness such as viral infection or diabetes can cause lost nerve function that effects this feedback signal. If the signal is diminished, the autonomic nervous system might push BP higher in order to create a feedback signal

that satisfies the control loop. Remember too, that erect position is demanding on the nervous system to maintain adequate blood flow to the brain. I am wondering if Conn's can also cause problems in autonomic nerve function. The autonomic nervous system expects a certain amount of blood vessel compliance and a certain range of blood storage capacity. If this system if overfilled from edema, the nervous system has less control range to work with. If compliance is impaired, control effort will have less effect. Remember, Conn's damages compliance over time by causing proliferation of smooth muscle around the arteries. It also causes proliferation of heart myocytes that leads to congestive heart failure. CHF on it's own can cause secondary aldosteronism. That is to say that CHF will promote aldosterone that is outside of the normal renin/angiotenion/ACE pathway. I think to

Dr. Grim's article about the progression of Conn's you can add a last chapter with CHF that drives the bus over the cliff, so to speak. The CHF is a consequence of untreated PA that complicates it with secondary aldosteronism. The treatment approach is still aldosterone blockade and low salt. This is deadly serious business to manage PA properly and early. It needs to be managed before there are important changes to the heart, brain white matter and other target organs. You will want to read PMID 15947892 "Effect of aldosterone and MR blockade on the brain and Kidney". I think Dr. Grim's idea of potassium playing a role is right. I looked on Pubmed for the relationship but I haven't found much there. There are a few articles but they are so old there isn't any abstract available. There is one called "Vagal Control of Heart Rate is modulated by extracellular Potassium. Pubmed ID 11130960

on Pubmed.com. Dr Grim mentions that google searching makes it difficult to find useful information. The way I use google is to search on Pubmed.com first. If there is an article that's of interest, I enter the full title into google. Often I find one of the professional services has posted the PDF full text online for free. Search on Pubmed first. Pubmed is commercial-free professional grade work. To: hyperaldosteronism Sent: Sat, March 27, 2010 1:56:05 PMSubject: Re: Neuropathy

Can you elaborate on autonomic neuropathy with sympathetic excess? I googled a bit, find much on autonomic neuropathy related to diabetes which I do not have.. not much on the sympathetic excess relationship.

I had a 48 hr BP monitor in 2008 which showed that my BP dropped to my normal of 90/60 while asleep; up to 135/85ish pretty much as soon as I got up out of bed. That was two years ago so don't know if it is the same now. At that time aldo was normal and renin low; Jan '10 results show aldo high and renin normal but I was on ACE and BB then so endo wanted to repeat. I had repeat aldo/renin this week, no results yet.

> >>>>>>> > > >

> >>>>>>>

> >>>>>> > > > Many have pains cramps in hands legs and feet. Tell

> >>>>>> us more about

> >>>>>>>

> >>>>>> > > the

> >>>>>>> > > > neuropathy please. BS K been

> >>>>>> low?

> >>>>>>> > > >

> >>>>>>> > > > Tiped sad Send

> >>>>>> form mi

> >>>>>>> > > > iPhone ;-)

> >>>>>>> > >

> >>>>>> >

> >>>>>>> > > > May your pressure be low!

> >>>>>>> >

> >>>>>> > >

> >>>>>>> > > > CE Grim MD

> >>>>>>> > > >

> >>>>>> Specializing in Difficult

> >>>>>>> > > >

> >>>>>> Hypertension

> >>>>>>> > > >

> >>>>>>> > > > On Mar

> >>>>>> 21, 2010, at 4:54 PM, Zhen

> >>>>>> C

> >>

> >>

> >>

> >>

> >

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[Guest guest]

Did you have any trouble with bloating and hypertension while on the CCB for the retest? I'm about to do the renin/aldosterone ratio. I'm not looking forward to this after finally "drying out" with Eplerenone. Best of luck with your AVS. To: "hyperaldosteronism "

<hyperaldosteronism >Sent: Sat, March 27, 2010 2:31:35 PMSubject: Re: Re: Neuropathy

Kim my Aldo was high and renin normal the first time I tested. I was on ace inhibitor also. After 2 weeks on verapamil I was retested and ny renin was low. I have since done the saline suppression test, ct and next week will have the AVS.

[Guest guest]

Thanks for your input. I have a colleague who does SNS testing and will ask him about low K.CE Grim MDI'm still trying to find answers to this question. At one point in my illness, they did a tilt table and BP went up when changing from horizontal to vertical position. Normal would be a minimal drop and orthostatic hypotension would present with a drop in BP with head up. There is a nice collection of articles on www.ans-hrv.com concerning autonomic testing and treatment. The arteries and heart have stretch receptors that monitor blood pressure. These signal the autonomic nervous system through the vagus nerve. An illness such as viral infection or diabetes can cause lost nerve function that effects this feedback signal. If the signal is diminished, the autonomic nervous system might push BP higher in order to create a feedback signal that satisfies the control loop. Remember too, that erect position is demanding on the nervous system to maintain adequate blood flow to the brain. I am wondering if Conn's can also cause problems in autonomic nerve function. The autonomic nervous system expects a certain amount of blood vessel compliance and a certain range of blood storage capacity. If this system if overfilled from edema, the nervous system has less control range to work with. If compliance is impaired, control effort will have less effect. Remember, Conn's damages compliance over time by causing proliferation of smooth muscle around the arteries. It also causes proliferation of heart myocytes that leads to congestive heart failure. CHF on it's own can cause secondary aldosteronism. That is to say that CHF will promote aldosterone that is outside of the normal renin/angiotenion/ACE pathway. I think to Dr. Grim's article about the progression of Conn's you can add a last chapter with CHF that drives the bus over the cliff, so to speak. The CHF is a consequence of untreated PA that complicates it with secondary aldosteronism. The treatment approach is still aldosterone blockade and low salt. This is deadly serious business to manage PA properly and early. It needs to be managed before there are important changes to the heart, brain white matter and other target organs. You will want to read PMID 15947892 "Effect of aldosterone and MR blockade on the brain and Kidney". I think Dr. Grim's idea of potassium playing a role is right. I looked on Pubmed for the relationship but I haven't found much there. There are a few articles but they are so old there isn't any abstract available. There is one called "Vagal Control of Heart Rate is modulated by extracellular Potassium. Pubmed ID 11130960 on Pubmed.com. Dr Grim mentions that google searching makes it difficult to find useful information. The way I use google is to search on Pubmed.com first. If there is an article that's of interest, I enter the full title into google. Often I find one of the professional services has posted the PDF full text online for free. Search on Pubmed first. Pubmed is commercial-free professional grade work. From: smkushka <smkushka>To: hyperaldosteronism Sent: Sat, March 27, 2010 1:56:05 PMSubject: Re: Neuropathy Can you elaborate on autonomic neuropathy with sympathetic excess? I googled a bit, find much on autonomic neuropathy related to diabetes which I do not have.. not much on the sympathetic excess relationship.I had a 48 hr BP monitor in 2008 which showed that my BP dropped to my normal of 90/60 while asleep; up to 135/85ish pretty much as soon as I got up out of bed. That was two years ago so don't know if it is the same now. At that time aldo was normal and renin low; Jan '10 results show aldo high and renin normal but I was on ACE and BB then so endo wanted to repeat. I had repeat aldo/renin this week, no results yet.> >>>>>>> > > >> >>>>>>> > >>>>>> > > > Many have pains cramps in hands legs and feet. Tell > >>>>>> us more about > >>>>>>> > >>>>>> > > the> >>>>>>> > > > neuropathy please. BS K been > >>>>>> low?> >>>>>>> > > >> >>>>>>> > > > Tiped sad Send > >>>>>> form mi> >>>>>>> > > > iPhone ;-)> >>>>>>> > > > >>>>>> >> >>>>>>> > > > May your pressure be low!> >>>>>>> > > >>>>>> > >> >>>>>>> > > > CE Grim MD> >>>>>>> > > > > >>>>>> Specializing in Difficult> >>>>>>> > > > > >>>>>> Hypertension> >>>>>>> > > >> >>>>>>> > > > On Mar > >>>>>> 21, 2010, at 4:54 PM, Zhen > >>>>>> C> >>> >>> >>> >>> >>

[Guest guest]

Vicki: always give us the numbers and normals for your renins and aldos as Low normal renin is not normal if aldo is high.CE Grim MDDid you have any trouble with bloating and hypertension while on the CCB for the retest? I'm about to do the renin/aldosterone ratio. I'm not looking forward to this after finally "drying out" with Eplerenone. Best of luck with your AVS. From: Vicki Ritchie <vritchie147>To: "hyperaldosteronism " <hyperaldosteronism >Sent: Sat, March 27, 2010 2:31:35 PMSubject: Re: Re: Neuropathy Kim my Aldo was high and renin normal the first time I tested. I was on ace inhibitor also. After 2 weeks on verapamil I was retested and ny renin was low. I have since done the saline suppression test, ct and next week will have the AVS.

[Guest guest]

Do you think this is what my facial spasm, neck, arm,leg etc maybe then?I just wanted to say thanks to everyone trying to help me. I'm sorry I've gone on so much this past month. I go in the metabolic unit tomorrow so ill come and post my results end of the weeks testing.Hopefully ill get some big clues or the answers to my puzzle.TcMandySent using BlackBerry® from OrangeDate: Sun, 28 Mar 2010 01:29:17 -0500To: <hyperaldosteronism >Subject: Re: Re: Neuropathy Vicki: always give us the numbers and normals for your renins and aldos as Low normal renin is not normal if aldo is high.CE Grim MDDid you have any trouble with bloating and hypertension while on the CCB for the retest? I'm about to do the renin/aldosterone ratio. I'm not looking forward to this after finally "drying out" with Eplerenone. Best of luck with your AVS. From: Vicki Ritchie <vritchie147>To: "hyperaldosteronism " <hyperaldosteronism >Sent: Sat, March 27, 2010 2:31:35 PMSubject: Re: Re: Neuropathy Kim my Aldo was high and renin normal the first time I tested. I was on ace inhibitor also. After 2 weeks on verapamil I was retested and ny renin was low. I have since done the saline suppression test, ct and next week will have the AVS.

[Guest guest]

My bp was high for a week to a week and a half after starting verapomil. I also had a bad headache. I am still on it and doing pretty well. Sent from my iPod

Did you have any trouble with bloating and hypertension while on the CCB for the retest? I'm about to do the renin/aldosterone ratio. I'm not looking forward to this after finally "drying out" with Eplerenone. Best of luck with your AVS. From: Vicki Ritchie <vritchie147>To: "hyperaldosteronism "

<hyperaldosteronism >Sent: Sat, March 27, 2010 2:31:35 PMSubject: Re: Re: Neuropathy

Kim my Aldo was high and renin normal the first time I tested. I was on ace inhibitor also. After 2 weeks on verapamil I was retested and ny renin was low. I have since done the saline suppression test, ct and next week will have the AVS.

[Guest guest]

Some on CCBs have headaches get better others worse. Did it help the HAs?My bp was high for a week to a week and a half after starting verapomil. I also had a bad headache. I am still on it and doing pretty well. Sent from my iPodOn Mar 28, 2010, at 12:52 AM, Zhen Chu <zhenchuymail> wrote: Did you have any trouble with bloating and hypertension while on the CCB for the retest? I'm about to do the renin/aldosterone ratio. I'm not looking forward to this after finally "drying out" with Eplerenone. Best of luck with your AVS. From: Vicki Ritchie <vritchie147>To: "hyperaldosteronism " <hyperaldosteronism >Sent: Sat, March 27, 2010 2:31:35 PMSubject: Re: Re: Neuropathy Kim my Aldo was high and renin normal the first time I tested. I was on ace inhibitor also. After 2 weeks on verapamil I was retested and ny renin was low. I have since done the saline suppression test, ct and next week will have the AVS.

[Guest guest]

Right. But little data collected on this. CE Grim MDOn Mar 28, 2010, at 8:37 AM, Francis Bill SUSPECTED PA wrote:It would seem that PA changes at least two electrolytes in our system. It would seem that electrolytes are what makes our system carry nerve electricity. If this is true then our nervous system is going to be impaired. > > > >>>>>>> > > >> > > >>>>>>>> > > >>>>>> > > > Many have pains cramps in hands legs and feet. Tell> > > >>>>>> us more about> > > >>>>>>>> > > >>>>>> > > the> > > >>>>>>> > > > neuropathy please. BS K been> > > >>>>>> low?> > > >>>>>>> > > >> > > >>>>>>> > > > Tiped sad Send> > > >>>>>> form mi> > > >>>>>>> > > > iPhone ;-)> > > >>>>>>> > >> > > >>>>>> >> > > >>>>>>> > > > May your pressure be low!> > > >>>>>>> >> > > >>>>>> > >> > > >>>>>>> > > > CE Grim MD> > > >>>>>>> > > >> > > >>>>>> Specializing in Difficult> > > >>>>>>> > > >> > > >>>>>> Hypertension> > > >>>>>>> > > >> > > >>>>>>> > > > On Mar> > > >>>>>> 21, 2010, at 4:54 PM, Zhen> > > >>>>>> C> > > >>> > > >>> > > >>> > > >>> > > >> > >> >> >> >> >> >>

[Guest guest]

Here is how you can do it at home or the Dr office as a screen. Have someone take your BP 3 times or more after lying on the bed for at least 5 min.Then stand up at the edge of the bed with your BP arm supported on something so that the cuff is at your heart level. This is very important taking it with the arm hanging down will miss the fall.Take BP each minute for 1, 2, 3, 4, and 5 min. Time it so the systolic reading is taken as close to each minute as possible. This means you need to start inflation about 30 sec before the minute reading.After this flex up and down on your toes slowly for 1 minute and recheck BP. Send us results.We need a section to describe how to do this and some questions about SNS symptoms. I think someone is working on this but I am not keeping track of who is doing what and we need someone to do this. Volunteers?CE Grim MDOn Mar 28, 2010, at 9:10 AM, Francis Bill SUSPECTED PA wrote:Some on here may also have Postural Orthostatic Tachycardia Syndrome.One of the ED Dr. thought I should have the tilt table test done. It is something they don't do at the local VA. Would have to go to Boston VA a three hour drive. My main Dr doesn't think it would show any thing.> > > >>>>>>> > > >> > > >>>>>>>> > > >>>>>> > > > Many have pains cramps in hands legs and feet. Tell> > > >>>>>> us more about> > > >>>>>>>> > > >>>>>> > > the> > > >>>>>>> > > > neuropathy please. BS K been> > > >>>>>> low?> > > >>>>>>> > > >> > > >>>>>>> > > > Tiped sad Send> > > >>>>>> form mi> > > >>>>>>> > > > iPhone ;-)> > > >>>>>>> > >> > > >>>>>> >> > > >>>>>>> > > > May your pressure be low!> > > >>>>>>> >> > > >>>>>> > >> > > >>>>>>> > > > CE Grim MD> > > >>>>>>> > > >> > > >>>>>> Specializing in Difficult> > > >>>>>>> > > >> > > >>>>>> Hypertension> > > >>>>>>> > > >> > > >>>>>>> > > > On Mar> > > >>>>>> 21, 2010, at 4:54 PM, Zhen> > > >>>>>> C> > > >>> > > >>> > > >>> > > >>> > > >> > >> >> >> >> >> >>

[Guest guest]

I've been given Cardizem and told to adjust the dose (increase as I go along) while I drop the usual meds. I've had Cardizem before. It raises blood sugar some. I've had Procardia XL years ago and I had terrible headache from that. It added forty points to blood sugars too. Fortunately, this experiment will only take a few weeks. To: hyperaldosteronism Sent: Sun, March 28, 2010 11:46:07 AMSubject: Re: Re: Neuropathy

Some on CCBs have headaches get better others worse. Did it help the HAs?My bp was high for a week to a week and a half after starting verapomil. I also had a bad headache. I am still on it and doing pretty well. Sent from my iPodOn Mar 28, 2010, at 12:52 AM, Zhen Chu

<zhenchuymail (DOT) com> wrote: Did you have any trouble with bloating and hypertension while on the CCB for the retest? I'm about to do the renin/aldosterone ratio. I'm not looking forward to this after finally "drying out" with Eplerenone. Best of luck with your AVS. From: Vicki Ritchie <vritchie147>To: "hyperaldosteronism @yahoogroups. com" <hyperaldosteronism@ yahoogroups. com>Sent: Sat, March 27, 2010 2:31:35 PMSubject: Re: [hyperaldosteronism ] Re: Neuropathy Kim my Aldo was high and renin normal the first time I tested. I was on ace inhibitor also. After 2 weeks on verapamil I was retested and ny renin was low. I have since done the saline suppression

test, ct and next week will have the AVS.

[Guest guest]

If you have any say in the choice of testing, you can learn the most by having the ANSAR test. This test is less subject to interpretation and impressions than a tilt table test. You can find an explanation at http://www.ans-hrv.com/introduction.htm . They have some excellent powerpoint explanations about the autonomic nervous system and this test method. There is also an exe file that is a slide show presentation. The ANSAR test system combines the classical nervous system challenges into on fifteen minute test. For instance, response to deep breathing, 15/30 ratio, valsalva maneuver, postural change from seated to standing are all examined. Blood pressure is

measured throughout the test. Heart rate variability is measured continuously and the power spectrum of the heart beat period is calculated using wavelet transform. Since the autonomic nervous system function will be seen in the instant to instant heart beat interval, the response of the ANS is examined directly for each of these challenges. Frequency domain analysis of the heart r-r interval allows the function of the sympathetic and parasympathetic nervous system to be observed for each of these challenges. This gives much greater insight to ANS issues than watching BP rise or crash from standing or head up tilt. It replaces impressions with hard numbers. Response to medications can be compared - medications alter ANS function. This test is superior to other tests because the mathematical calculations in the wavelet transform are synchronized to the respiratory rate. There are other ANS

measurement systems, but they don't synchronize the measurements to the respiratory rate. The respiratory rate is a key input to the ANS, because volume in the chest varies as you inhale or exhale. The ANS compensates for this variation in chest volume in real time through the vegus nerve activity. When ANS function deteriorates, heart rate variation in response to respiration are diminished. This is comparatively difficult to quantify in a tilt table exam. To: hyperaldosteronism Sent: Sun, March 28, 2010 10:10:46 AMSubject: Re: Neuropathy

Some on here may also have Postural Orthostatic Tachycardia Syndrome.

One of the ED Dr. thought I should have the tilt table test done. It is something they don't do at the local VA. Would have to go to Boston VA a three hour drive. My main Dr doesn't think it would show any thing.