Phrenic nerve involvement in CMT

[Guest guest]

Dear ers,

I have just scanned the National Library of Medicine for " CMT Phrenic

Nerve involvement " . Below is the latest research from last October

2005. There are only 14 abstracts listed, dating as far back as April

1987 - that's almost 20 years now. ~ Gretchen

Tenn Med. 2005 Oct;98(10):495-7.

Phrenic nerve involvement in Charcot-Marie-Tooth disease.

Abboud L, El SF, Takubo T, Byrd RP Jr, Roy TM.

H. Quillen Veterans Affairs Medical Center, Mountain Home, TN

37684-4000, USA.

Diaphragmatic weakness in Charcot-Marie-Tooth (CMT) disease may be

more common than generally acknowledged. Recognizing diaphragmatic

weakness in a patient with CMT is important since recognition of this

process may help explain the symptoms of breathlessness and

orthopnea, as well as the development of hypercarbia. Although most

patients with CMT have a normal lifespan, the subset of patients with

diaphragmatic weakness may be at a higher risk of pulmonary morbidity

and early mortality. Elevation of one or both hemidiaphragms on chest

roentgenogram should raise the suspicion of diaphragmatic dysfunction

and prompt further investigation.

[Guest guest]

Ugh!

Thanks for finding this

Larry