spontaneous mutations

February 26, 2006

I am the first/ only in my family to show signs of CMT. Mom had 6

borthers and sisters and none of my cousins are affected. Dad had a

brother and none of his children are affected. I'm the special

one .

I started questing and blaming myself with my neurologist, saying

maybe it was working too hard or having a baby. He stopped me and

reminded me that CMT is coded into my genes. I cannot control the

progression. I can be careful, and do all that I can to prevent

injury and fatigue, but I cannot control my future. I cannot

internalize responsiblity for my symptoms. It was a good reminder.

I had Athena come out 2 weeks ago and maybe those results will give

me some insights for management and cause, though I think I may be

one of those spontanious mutations.

So much of the medical world is still a mystery.

Take care,

Lenka

March 16, 2007

Heard Couric last night on the news mention something about this.

I think maybe it was this study.http://www.newsday.com/news/health/ny-hsauti0316,0,6024589.story?coll=ny-leadhealthnews-headlines

In this new study, published Friday in Science, Sebat,

Wigler and their colleagues found that 10 percent of the 195 autistic patients they studied had evidence of tiny spontaneous chromosomal mutations -- each with a different gene involved. Ultimately, Sebat said he believes this could help some parents who are seeking to have more children but fearful that they will take another genetic hit with their next child.

A spontaneous mutation means it is not inherited.

In blood samples from the autistic patients and an equal number of

unaffected siblings and parents, 10 percent of them had spontaneous genetic mutations compared with 1 percent of those in a control group. In families with more than one autistic child, there were very few of these spontaneous chromosomal rearrangements. It's akin to a reshuffling of the chromosomes.

But what was most surprising is that all of the mutations appeared at

different places along the genome, suggesting, as Sebat said, "that there are so many possible places where you can get a hit."

The end result of these genetic mutations is that these children have

impaired social interactions, difficulty communicating, restricted interests and language deficits.

March 16, 2007

Robin,

Since Thimerosal is a mutagen and teratogen and

Thimerosal-preserved preparations have been

being injected into, applied to, otherwise taken

by, men and women, including pregnant women, for

several decades, I would question the understanding

of reality of anyone who attempts to pass off the

genetic mutations found as " spontaneous. "

This is an implicit admission that " its genetic "

is a hypothesis that is NOT supported by the facts

as well as a " hypothesis " designed to give cover

to the healthcare establishment for the major

causative factor, knowing mercury poisoning, that

appears to be the major underlying cause for the

overal harm to the public health.

In addition to Thimerosal, Bisphenol A, PCBs,

PBBs, and dioxins are but a few of the chemicals

we are being exposed to that may induce genetic

mutations.

Hopefully, we understand that calling these

mutations " spontaneous " is but another indirect

attempt to exonerate the healthcare establishment's

knowing mercury poisoning of us all by Thimerosal

(49.55% mercury by weight) and related organic (e.g.,

phenylmercury acetate, boprate, and nitrate) and

inorganic (e.g., Calomel [mercurous chloride])

MERCURY compounds for more than a century.

Respectfully,

Dr. King

http://www.dr-king.com

PS: For those interested in the history of

flu vaccination recommendations, I have

attached a " pdf " version of the April 2002

discussion of influenza vaccination

recommendations and the erratum file.

Those who read this will note that flu

shots were being routinely recommended

for pregnant women by some OBs long

before the CDC took action to officially

recommend pregnant women be vaccinated

in 2002.

+++++++++++++++++++++++++++++++++++

At 05:02 3/16/07 -0700, Robin@... wrote:

>

>Heard Couric last night on the news mention

>something about this. I think maybe it was this study.

>

>http://www.newsday.com/news/health/ny-hsauti0316,0,6024589.story?coll=ny-le

adhealthnews-headlines

>

>In this new study, published Friday in Science,

> Sebat, Wigler and their colleagues

>found that 10 percent of the 195 autistic patients

>they studied had evidence of tiny spontaneous

>chromosomal mutations -- each with a different gene

>involved. Ultimately, Sebat said he believes this

>could help some parents who are seeking to have

>more children but fearful that they will take

>another genetic hit with their next child.

>

>A spontaneous mutation means it is not inherited.

>

>In blood samples from the autistic patients and

>an equal number of unaffected siblings and parents,

>10 percent of them had spontaneous genetic mutations

>compared with 1 percent of those in a control group.

>In families with more than one autistic child,

>there were very few of these spontaneous chromosomal

>rearrangements. It's akin to a reshuffling of the

>chromosomes.

>

>But what was most surprising is that all of the

>mutations appeared at different places along the

>genome, suggesting, as Sebat said, " that there

>are so many possible places where you can get a hit. "

>

>The end result of these genetic mutations is that

>these children have impaired social interactions,

>difficulty communicating, restricted interests and

>language deficits.

><snip>

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<H1>Erratum: Vol. 51, No. RR-3</FONT></H1>

<P>The <I>MMWR Recommendations and Reports</I>, " <A=20

=

href=3D " http://www.cdc.gov/mmwr/preview/mmwrhtml/rr5103a1.htm " >Prevention=

=20

and Control of Influenza: Recommendations of the Advisory =

Committee on=20

Immunization Practices</A>, " published on April 12, 2002, =

contained an=20

inconsistency in the recommended timing of vaccination of target =

groups.=20

In the section, " Vaccination in October and November, " persons at=20

increased risk for influenza-related complications (e.g., persons =

aged=20

<U> & gt;</U>65 years and persons aged 6 months--64 years with =

high-risk=20

medical conditions) and health-care workers were recommended for=20

vaccination in October. In addition, children aged 6 months to =

& lt;9 years=20

receiving influenza vaccine for the first time need a booster dose =

<U> & gt;</U>1 month after the first dose and, thus, also were =

recommended=20

to be vaccinated in October or earlier. However, in the section, =

" Timing=20

of Organized Vaccination Campaigns, " household contacts of persons =

at high=20

risk were also included among those recommended to begin =

vaccination in=20

October, but children aged & lt;9 years receiving vaccine for the =

first=20

time were not discussed. </P>

<P>To clarify, vaccination of the following groups should begin in =

October, regardless of the setting in which a person receives =

vaccination:=20

</P>

<UL>

<LI>persons at increased risk for influenza-related =

complications=20

(persons aged <U> & gt;</U>65 years, persons aged 6 months--64 =

years with=20

certain medical conditions, and healthy children aged 6--23 =

months);*=20

<LI>health-care workers;=20

<LI>household contacts of persons at increased risk for=20

influenza-related complications (including contacts of infants =

aged=20

& lt;6 months who are not eligible for influenza vaccine); and=20

<LI>children aged 6 months to & lt;9 years receiving influenza =

vaccine=20

for the first time. </LI></UL>

<P>The current projected distribution of U.S. influenza vaccine =

for=20

2002--2003, on the basis of aggregate manufacturer's estimates, is =

92--97=20

million doses, with the majority of doses expected to be =

distributed by=20

the end of October. This projection is based on early estimates =

and might=20

change as the season progresses. Thus, supplies are expected to be =

adequate for prioritization of persons at increased risk for =

influenza=20

complications, their household contacts, and health-care workers =

for=20

vaccination in October. </P><SMALL>

<P>* This group also might be offered vaccination in September, if =

available, when seen for routine care or during hospitalization to =

avoid=20

missed opportunities for vaccination. </SMALL></P>

<P>

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{

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=20

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function openHelp()

{

newwindow=3Dwindow.open(deRef + 'printhelp.html','PrintHelp', =

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/************************ ADDITIONAL FEATURES ************************

Plugins

*/

/************************** CONFIG SECTION **************************/

/* You may add or alter any code config here. */

/* Specify the life time of the cookie in seconds, or */

/* set to " Session " to turn off persistent cookies. */

var s_cookieLifetime=3D " Session "

/* Variables (s_pageName, s_prop1, etc.) not prefixed with " s_ " will not =

be used. */

var s_disableLegacyVars=3Dtrue

/* E-commerce Config */

var s_eVarCFG=3D " "

/* Link Tracking Config */

var s_trackDownloadLinks=3Dtrue

var s_trackExternalLinks=3Dtrue

var s_trackInlineStats=3Dtrue

var =

s_linkDownloadFileTypes=3D " exe,zip,wav,mp3,mov,mpg,avi,doc,pdf,xls,rm,wmv=

,rtf,ppt,swf,prc,xml "

var =

s_linkInternalFilters=3D " javascript:,cdc,file:///,outbind,//www/,mid://,c=

dc "

var s_linkLeaveQueryString=3Dfalse

var s_linkTrackVars=3D " None "

var s_linkTrackEvents=3D " None "

/* Plugin Config */

var s_usePlugins=3Dtrue

function s_doPlugins() {

var =

ds=3D[ " bam.gov " , " cdc.gov " , " 5aday.gov " , " mid:// " , " http://198.246.96.2 " , " out=

bind: " ];

var dlh=3Ds_wd.location.href.toLowerCase();

var cond=3Dfalse;

for(var i=3D0;i<ds.length;i++) {

if(dlh.indexOf(ds)!=3D-1) cond=3Dtrue;

}

if(cond=3D=3Dfalse) s_vpr( " s_prop10 " ,dlh);

/* check for trade mark symbol */

spn=3Descape(s_pageName);

pn=3D(spn.indexOf(' & trade;')!=3D-1)?spn.split(' & trade;'):'';

pn=3D(spn.indexOf('%u2122')!=3D-1)?spn.split('%u2122'):pn;

pn=3D(spn.indexOf('%28tm%29')!=3D-1)?spn.split('%28tm%29'):pn;

if(pn!=3D''){

s_vp_stripTrade(pn);

}

if(!window.s_campaign)

s_vp_getCGI('s_campaign','s_cid');

}

/************************** PLUGINS SECTION *************************/

/* You may insert any plugins you wish to use here. */

/*

* Plugin: Strip & trade; from s_pageName

*/

function s_vp_stripTrade(pn)

{s_vpr( " s_pageName " ,unescape(pn[0])+unescape(pn[1]));}

/*

* Plugin: Get Plugin Modified Value

*/

function s_vp_getValue(vs)

{var k=3Dvs.substring(0,2)=3D=3D's_'?vs.substring(2):vs;return s_wd[

's_vpm_'+k]?s_wd['s_vpv_'+k]:s_gg(k)}

/*

* Plugin: Get Query String CGI Variable Value

*/

function s_vp_getCGI(vs,k)

{var v=3D'';if(k & & s_wd.location.search){var q=3Ds_wd.location.search,

qq=3Dq.indexOf('?');q=3Dqq<0?q:q.substring(qq+1);v=3Ds_pt(q,' & ',s_cgif,

k)}s_vpr(vs,v)}function s_cgif(t,k){if(t){var te=3Dt.indexOf('=3D'),

sk=3Dte<0?t:t.substring(0,te),sv=3Dte<0?'True':t.substring(te+1);if(

sk=3D=3Dk)return s_epa(sv)}return ''}

/*

* Plugin: Get Value From Cookie

*/

function s_vp_getCookie(vs,k)

{s_vpr(vs,s_c_r(k))}

/*

* Plugin: Set variable to value only once per time priod:

* (Min, Hour, Day, Month, Year)

* in the specified timezone (hour offset from GMT)

*/

function s_vp_setOncePer(vs,v,period,tzOffs)

{if(v){var n=3Ds_dt(tzOffs,0),t,st=3Ds_vh_gt(vs,v);st=3Dst?st:0;if(

!s_vh_s(vs,v))v=3D'';else if(st){t=3Ds_dt(tzOffs,st);var min=3D(

=

n.getMinutes()=3D=3Dt.getMinutes()),hour=3D(n.getHours()=3D=3Dt.getHours(=

)

=

),day=3D(n.getDate()=3D=3Dt.getDate()),mon=3D(n.getMonth()=3D=3Dt.getMont=

h()

=

),year=3D(n.getYear()=3D=3Dt.getYear());if(period=3D=3D'Ever'||(year & & ((

=

period=3D=3D'Year')||(mon & & ((period=3D=3D'Month')||(day & & ((period=3D=3D'D=

ay'

=

)||(hour & & ((period=3D=3D'Hour')||(min & & period=3D=3D'Min')))))))))){v=3D''=

}}

}s_vpr(vs,v)}

/*

* Plugin: Get State Of Form On Abandon

*/

function s_vp_getFormAbandonState(vs,lt,ln)

{if(!s_wd.s_vp_faolr){s_wd.s_vp_faol=3Ds_wd.onload;s_wd.onload=3D

s_vp_fas;s_wd.s_vp_favs=3Dvs;s_wd.s_vp_falt=3Dlt;s_wd.s_vp_faln=3Dln

s_wd.s_vp_faolr=3D1}}var s_vp_faolr=3D0;function s_vp_fas(e){var r=3D

true;if(s_wd.s_vp_faol)r=3Ds_wd.s_vp_faol(e);if(s_d.forms & &

s_d.forms.length>0){var vs=3Ds_wd.s_vp_favs,p=3Ds_gg('pageName'),fn,

f,en,el,t,oc,och;for(fn=3D0;fn<s_d.forms.length;fn++){f=3Ds_d.forms[

fn];if(vs & & !s_wd[vs])s_wd[vs]=3D(f.name?f.name:(p?p:''))

+':No Data Entered';for(en=3D0;en<f.elements.length;en++){el=3D

f.elements[en];t=3Del.type;if(t & & t.toUpperCase){t=3Dt.toUpperCase()

oc=3Del.onclick?el.onclick.toString():'';och=3Del.onchange?

el.onchange.toString():'';if(oc.indexOf( " s_vp_fac( " )<0 & &

=

och.indexOf( " s_vp_fac( " )<0){if(t=3D=3D'BUTTON'||t=3D=3D'CHECKBOX'||t=3D=3D=

=

'RADIO'||t=3D=3D'RESET'||t=3D=3D'SUBMIT'||t=3D=3D'IMAGE'){el.s_vp_faoc=3D=

el.onclick;if(((f.name & & oc.indexOf(f.name)>=3D0)||(oc.indexOf(

'form.')>=3D0)) & & oc.indexOf( " submit( " )>=3D0)el.onclick=3Ds_vp_fasu;else

el.onclick=3Ds_vp_fac}else{el.s_vp_faoch=3Del.onchange;if(((f.name & &

och.indexOf(f.name)>=3D0)||(och.indexOf('form.')>=3D0)) & & och.indexOf(

" submit( " )>=3D0)el.onchange=3Ds_vp_fasu;else el.onchange=3Ds_vp_fac }}}

}f.s_vp_faos=3Df.onsubmit;f.onsubmit=3Ds_vp_fasu}s_wd.s_vp_faul=3D

s_wd.onunload;s_wd.onunload=3Ds_vp_fa}return r}function s_vp_fa(e){

var vs=3Ds_wd.s_vp_favs;if(vs & & s_wd[vs]){s_lnk=3Dnew Object

s_linkType=3Ds_wd.s_vp_falt;s_linkName=3Ds_wd.s_vp_faln;s_gs('')

s_lnk=3D''}if(s_wd.s_ful)return s_wd.s_ful(e);return true}

function s_vp_fasu(e){var vs=3Ds_wd.s_vp_favs;if(vs)s_wd[vs]=3D'';if(

this.s_vp_faos)return this.s_vp_faos(e);if(this.s_vp_faoc)

return this.s_vp_faoc(e);if(this.s_vp_faoch)

return this.s_vp_faoch(e);return true}function s_vp_fac(e){var b=3D

" s_gs( " ,vs=3Ds_wd.s_vp_favs,f=3Dthis.form,p=3Ds_gg('pageName');if(vs)

s_wd[vs]=3D(f.name?f.name:(p?p:''))+':'+(this.name?this.name:'')

if(this.s_vp_faoc)return this.s_vp_faoc(e);if(this.s_vp_faoch)

return this.s_vp_faoch(e);return true}

/*

* Plugin Utilities v2.0 (Required For All Plugins)

*/

function s_vpr(vs,v){if(s_wd[vs])s_wd[vs]=3Ds_wd[vs];else s_wd[vs]=3D''

if(vs.substring(0,2) =3D=3D =

's_')vs=3Dvs.substring(2);s_wd['s_vpv_'+vs]=3Dv

s_wd['s_vpm_'+vs]=3D1}function s_dt(tz,t){var d=3Dnew =

Date;if(t)d.setTime(

t);d=3Dnew Date(d.getTime()+(d.getTimezoneOffset()*60*1000))

return new Date(Math.floor(d.getTime()+(tz*60*60*1000)))}

function s_vh_gt(k,v){var =

vh=3D'|'+s_c_r('s_vh_'+k),vi=3Dvh.indexOf('|'+v

+'=3D'),ti=3Dvi<0?vi:vi+2+v.length,pi=3Dvh.indexOf('|',ti),t=3Dti<0?'':

vh.substring(ti,pi<0?vh.length:pi);return t}function s_vh_gl(k){var

vh=3Ds_c_r('s_vh_'+k),e=3Dvh?vh.indexOf('=3D'):0;return =

vh?(vh.substring(0,

e?e:vh.length)):''}function s_vh_s(k,v){if(k & & v){var e=3Dnew Date,st=3D

e.getTime(),y=3De.getYear(),c=3D's_vh_'+k,vh=3D'|'+s_c_r©+'|',t=3Ds_vh_=

gt(k,

v);e.setYear((y<1900?y+1900:y)+5);if(t)vh=3Ds_rep(vh,'|'+v+'=3D'+t+'|','|=

'

);if(vh.substring(0,1)=3D=3D'|')vh=3Dvh.substring(1);if(vh.substring(

vh.length-1,vh.length)=3D=3D'|')vh=3Dvh.substring(0,vh.length-1);vh=3Dv

+'=3D[PCC]'+(vh?'|'+vh:'');s_c_w(c,vh,e);if(s_vh_gt(k,v)!=3D'[PCC]')

return 0;vh=3Ds_rep(vh,'[PCC]',st);s_c_w(c,vh,e)}return 1}

/************* DO NOT ALTER ANYTHING BELOW THIS LINE ! **************/

var =

s_un,s_ios=3D0,s_q=3D'',s_code=3D'',code=3D'',s_bcr=3D0,s_lnk=3D'',s_eo=3D=

'',

s_vb,s_pl,s_tfs=3D0,s_etfs=3D0,s_wd=3Dwindow,s_d=3Ds_wd.document,s_ssl=3D=

(

s_wd.location.protocol.toLowerCase().indexOf('https')>=3D0),s_n=3D

navigator,s_u=3Ds_n.userAgent,s_apn=3Ds_n.appName,s_v=3Ds_n.appVersion,

s_apv,s_i,s_ie=3Ds_v.indexOf('MSIE '),s_ns6=3Ds_u.indexOf('Netscape6/')

if(s_v.indexOf('Opera')>=3D0||s_u.indexOf('Opera')>=3D0)s_apn=3D'Opera';v=

ar

s_isie=3D(s_apn=3D=3D'Microsoft Internet =

Explorer'),s_isns=3D(s_apn=3D=3D

'Netscape'),s_isopera=3D(s_apn=3D=3D'Opera'),s_ismac=3D(s_u.indexOf('Mac'=

)>=3D0)

if(s_ie>0){s_apv=3DparseInt(s_i=3Ds_v.substring(s_ie+5));if(s_apv>3)s_apv=

=3D

parseFloat(s_i)}else if(s_ns6>0)s_apv=3DparseFloat(s_u.substring(s_ns6

+10));else s_apv=3DparseFloat(s_v);function s_fl(s,l){return (s+''

).substring(0,l)}function s_co(o){if(!o)return o;var n=3Dnew Object

for(x in o)n[x]=3Do[x];return n}function s_num(x){var =

s=3Dx.toString(),g=3D

'0123456789',p,d;for(p=3D0;p<s.length;p++){d=3Ds.substring(p,p+1);if(

g.indexOf(d)<0)return 0}return 1}function s_rep(s,o,n){var i=3D

s.indexOf(o),l=3Dn.length>0?n.length:1;while(s & & i>=3D0){s=3Ds.substring(0=

,i)

+n+s.substring(i+o.length);i=3Ds.indexOf(o,i+l)}return s}function s_ape(

s){return s?s_rep(escape(''+s),'+','%2B'):s}function s_epa(s){

return s?unescape(s_rep(''+s,'+',' ')):s}function s_pt(s,d,f,a){var t=3D

s,x=3D0,y,r;while(t){y=3Dt.indexOf(d);y=3Dy<0?t.length:y;t=3Dt.substring(=

0,y)

r=3Df(t,a);if®return =

r;x+=3Dy+d.length;t=3Ds.substring(x,s.length);t=3Dx<

s.length?t:''}return ''}function =

s_isf(t,a){if(t.substring(0,2)=3D=3D's_')

t=3Dt.substring(2);return (t!=3D'' & & t=3D=3Da)}function =

s_fsf(t,a){if(s_pt(a,

',',s_isf,t))s_fsg+=3D(s_fsg!=3D''?',':'')+t;return 0}var s_fsg

function s_fs(s,f){s_fsg=3D'';s_pt(s,',',s_fsf,f);return s_fsg}var

s_c_d=3D'';function s_c_gdf(t,a){if(!s_num(t))return 1;return 0}

function s_c_gd(){var d=3Ds_wd.location.hostname,n=3Ds_gg(

'cookieDomainPeriods'),p;if(d & & !s_c_d){n=3Dn?parseInt(n):2;n=3Dn>2?n:2;p=3D=

d.lastIndexOf('.');while(p>=3D0 & & n>1){p=3Dd.lastIndexOf('.',p-1);n--}

s_c_d=3Dp>0 & & s_pt(d,'.',s_c_gdf,0)?d.substring(p):''}return s_c_d}

function s_c_r(k){k=3Ds_ape(k);var c=3D' '+s_d.cookie,s=3Dc.indexOf(' =

'+k

+'=3D'),e=3Ds<0?s:c.indexOf(';',s),v=3Ds<0?'':s_epa(c.substring(s+2

+k.length,e<0?c.length:e));return v}function s_c_w(k,v,e){var d=3D

s_c_gd(),l=3Ds_gg('cookieLifetime');v=3D''+v;l=3Dl?(''+l).toUpperCase():'=

'

if(e & & l!=3D'SESSION' & & l!=3D'NONE'){l=3DparseInt(l);if(l){e=3Dnew Date

e.setTime(e.getTime()+(parseInt(l)*1000))}}if(k & & l!=3D'NONE'){

s_d.cookie=3Dk+'=3D'+s_ape(v)+'; path=3D/;'+(e & & l!=3D'SESSION'?' =

expires=3D'

+e.toGMTString()+';':'')+(d?' domain=3D'+d+';':'');return =

s_c_r(k)=3D=3Dv}

return 0}function s_cet(f,a,et,oe,fb){var r,d=3D0

/*@cc_on@if(@_jscript_version>=3D5){try{return f(a)}catch(e){return =

et(e)}d=3D1}@end@*/

if(!d){if(s_ismac & & s_u.indexOf('MSIE 4')>=3D0)return fb(a);else{

s_wd.s_oe=3Ds_wd.onerror;s_wd.onerror=3Doe;r=3Df(a);s_wd.onerror=3Ds_wd.s=

_oe

return r}}}function s_gtfset(e){return s_tfs}function s_gtfsoe(e){

s_wd.onerror=3Ds_wd.s_oe;s_etfs=3D1;var =

code=3Ds_gs(s_un);if(code)s_d.write(

code);s_etfs=3D0;return true}function s_gtfsfb(a){return s_wd}

function s_gtfsf(w){var p=3Dw.parent,l=3Dw.location;s_tfs=3Dw;if(p & &

p.location!=3Dl & & p.location.host=3D=3Dl.host){s_tfs=3Dp;return =

s_gtfsf(s_tfs)}

return s_tfs}function =

s_gtfs(){if(!s_tfs){s_tfs=3Ds_wd;if(!s_etfs)s_tfs=3D

s_cet(s_gtfsf,s_tfs,s_gtfset,s_gtfsoe,s_gtfsfb)}return s_tfs}

function s_ca(un){un=3Dun.toLowerCase();var =

ci=3Dun.indexOf(','),fun=3Dci<0?

un:un.substring(0,ci),imn=3D's_i_'+fun;if(s_d.images & & s_apv>=3D3 & &

!s_isopera & & (s_ns6<0||s_apv>=3D6.1)){s_ios=3D1;if(!s_d.images[imn] & & (

!s_isns||(s_apv<4||s_apv>=3D5))){s_d.write('<im'+'g name=3D " '+imn

+' " height=3D1 width=3D1 border=3D0 =

alt=3D " " >');if(!s_d.images[imn])s_ios=3D0}}}

function s_it(un){s_ca(un)}function s_mr(un,sess,q,ta){un=3D

un.toLowerCase();var =

ci=3Dun.indexOf(','),fun=3Dci<0?un:un.substring(0,ci

),unc=3Ds_rep(fun,'_','-'),imn=3D's_i_'+fun,im,b,e,rs=3D'http'+(s_ssl?'s'=

:''

)+'://mtrics.cdc.gov/b/ss/'+un+'/1/G.5-Pd-S/'

+sess+'?[AQB] & ndh=3D1'+(q?q:'')+(s_q?s_q:'')+' & [AQE]';if(s_ios){im=3Ds_wd=

[

imn]?s_wd[imn]:s_d.images[imn];if(!im)im=3Ds_wd[imn]=3Dnew =

Image;im.src=3Drs

if(rs.indexOf(' & pe=3D')>=3D0 & & (!ta||ta=3D=3D'_self'||ta=3D=3D'_top'||(s_w=

d.name & &

ta=3D=3Ds_wd.name))){b=3De=3Dnew =

Date;while(e.getTime()-b.getTime()<500)e=3D

new Date}return ''}return '<im'+'g sr'+'c=3D " '+rs

+' " width=3D1 height=3D1 border=3D0 alt=3D " " >'}function s_gg(v){var =

g=3D's_'+v

return s_wd[g]||s_wd.s_disableLegacyVars?s_wd[g]:s_wd[v]}var s_qav=3D''

function s_havf(t,a){var b=3Dt.substring(0,4),s=3Dt.substring(4),n=3D

parseInt(s),k=3D's_g_'+t,m=3D's_vpm_'+t,q=3Dt,v=3Ds_gg('linkTrackVars'),e=

=3D

s_gg('linkTrackEvents');if(!s_wd['s_'+t])s_wd['s_'+t]=3D'';s_wd[k]=3Ds_wd=

[

m]?s_wd['s_vpv_'+t]:s_gg(t);if(s_lnk||s_eo){v=3Dv?v+',pageName,charSet,'

+'cookieDomainPeriods,cookieLifetime,eVarCFG,purchaseID':'';if(v & &

!s_pt(v,',',s_isf,t))s_wd[k]=3D'';if(t=3D=3D'events' & & e)s_wd[k]=3Ds_fs(s_=

wd[k

],e)}s_wd[m]=3D0;if(t=3D=3D'charSet')q=3D'ce';else =

if(t=3D=3D'cookieDomainPeriods'

)q=3D'cdp';else if(t=3D=3D'cookieLifetime')q=3D'cl';else =

if(t=3D=3D'channel')q=3D

'ch';else if(t=3D=3D'campaign')q=3D'v0';else =

if(s_num(s)){if(b=3D=3D'prop')q=3D'c'

+n;else if(b=3D=3D'eVar')q=3D'v'+n;else =

if(b=3D=3D'hier')q=3D'h'+n}if(s_wd[k] & & t!=3D

'linkName' & & t!=3D'linkType')s_qav+=3D' & '+q+'=3D'+s_ape(s_wd[k]);return =

''}

function s_hav(){var n,av=3D'charSet,cookieDomainPeriods,cookieLifetime'

+',pageName,channel,server,pageType,campaign,state,zip,events,product'

+'s,purchaseID,eVarCFG,linkName,linkType';for(n=3D1;n<26;n++)av+=3D',prop=

'

+n+',eVar'+n+',hier'+n;s_qav=3D'';s_pt(av,',',s_havf,0);return s_qav}

function =

s_lnf(t,h){t=3Dt?t.toLowerCase():'';h=3Dh?h.toLowerCase():'';var

te=3Dt.indexOf('=3D');if(t & & te>0 & & h.indexOf(t.substring(te+1))>=3D0)

return t.substring(0,te);return ''}function s_ln(h){if(s_gg(

'linkNames'))return s_pt(s_gg('linkNames'),',',s_lnf,h);return ''}

function =

s_ltdf(t,h){t=3Dt?t.toLowerCase():'';h=3Dh?h.toLowerCase():'';var

qi=3Dh.indexOf('?');h=3Dqi>=3D0?h.substring(0,qi):h;if(t & & h.substring(

h.length-(t.length+1))=3D=3D'.'+t)return 1;return 0}function =

s_ltef(t,h){

t=3Dt?t.toLowerCase():'';h=3Dh?h.toLowerCase():'';if(t & & h.indexOf(t)>=3D0=

)

return 1;return 0}function s_lt(h){var lft=3Ds_gg(

'linkDownloadFileTypes'),lef=3Ds_gg('linkExternalFilters'),lif=3Ds_gg(

'linkInternalFilters')?s_gg('linkInternalFilters'):

s_wd.location.hostname;h=3Dh.toLowerCase();if(s_gg('trackDownloadLinks'

) & & lft & & s_pt(lft,',',s_ltdf,h))return 'd';if(s_gg('trackExternalLinks'

) & & (lef||lif) & & (!lef||s_pt(lef,',',s_ltef,h)) & & (!lif||!s_pt(lif,',',

s_ltef,h)))return 'e';return ''}function s_lc(e){s_lnk=3Ds_co(this)

s_gs('');s_lnk=3D'';if(this.s_oc)return this.s_oc(e);return true}

function s_ls(){var l,ln,oc;for(ln=3D0;ln<s_d.links.length;ln++){l=3D

s_d.links[ln];oc=3Dl.onclick?l.onclick.toString():'';if(oc.indexOf(

" s_gs( " )<0 & & oc.indexOf( " s_lc( " )<0){l.s_oc=3Dl.onclick;l.onclick=3Ds_lc}}}=

function s_bc(e){s_eo=3De.srcElement?e.srcElement:e.target;s_gs('')

s_eo=3D''}function s_ot(o){var x=3Do.type,y=3Do.tagName;return (x & &

x.toUpperCase?x:y & & y.toUpperCase?y:o.href?'A':'').toUpperCase()}

function s_oid(o){var =

t=3Ds_ot(o),p=3Do.protocol,c=3Do.onclick,n=3D'',x=3D0;if(

!o.s_oid){if(o.href & & (t=3D=3D'A'||t=3D=3D'AREA') & & (!c||!p||p.toLowerCase(=

).indexOf('javascript')<0))n=3Do.href;else if©{n=3Ds_rep(s_rep(s_rep(

s_rep(c.toString(), " \r " ,''), " \n " ,''), " \t " ,''),' ','');x=3D2}else if(

o.value & & (t=3D=3D'INPUT'||t=3D=3D'SUBMIT')){n=3Do.value;x=3D3}else =

if(o.src & & t=3D=3D

'IMAGE')n=3Do.src;if(n){o.s_oid=3Ds_fl(n,100);o.s_oidt=3Dx}}return =

o.s_oid}

function s_rqf(t,un){var =

e=3Dt.indexOf('=3D'),u=3De>=3D0?','+t.substring(0,e)

+',':'';return u & & u.indexOf(','+un+',')>=3D0?s_epa(t.substring(e+1)):''}

function s_rq(un){var =

c=3Dun.indexOf(','),v=3Ds_c_r('s_sq'),q=3D'';if(c<0)

return s_pt(v,' & ',s_rqf,un);return s_pt(un,',',s_rq,0)}var s_sqq,s_squ

function s_sqp(t,a){var =

e=3Dt.indexOf('=3D'),q=3De<0?'':s_epa(t.substring(e

+1));s_sqq[q]=3D'';if(e>=3D0)s_pt(t.substring(0,e),',',s_sqs,q);return =

0}

function s_sqs(un,q){s_squ[un]=3Dq;return 0}function s_sq(un,q){s_sqq=3D

new Object;s_squ=3Dnew Object;s_sqq[q]=3D'';var =

k=3D's_sq',v=3Ds_c_r(k),x,c=3D0

s_pt(v,' & ',s_sqp,0);s_pt(un,',',s_sqs,q);v=3D'';for(x in s_squ)s_sqq[

s_squ[x]]+=3D(s_sqq[s_squ[x]]?',':'')+x;for(x in s_sqq)if(x & & s_sqq[x] & & (

x=3D=3Dq||c<2)){v+=3D(v?' & ':'')+s_sqq[x]+'=3D'+s_ape(x);c++}return =

s_c_w(k,v,0

)}function s_wdl(e){s_wd.s_wd_l=3D1;var =

r=3Dtrue;if(s_wd.s_ol)r=3Ds_wd.s_ol(

e);if(s_wd.s_ls)s_wd.s_ls();return r}function s_wds(un){un=3D

un.toLowerCase();s_wd.s_wd_l=3D1;if(s_apv>3 & & (!s_isie||!s_ismac||s_apv>=3D=

5)){s_wd.s_wd_l=3D0;if(!s_wd.s_unl)s_wd.s_unl=3Dnew Array;s_wd.s_unl[

s_wd.s_unl.length]=3Dun;if(s_d.body & & s_d.body.attachEvent){if(

!s_wd.s_bcr & & s_d.body.attachEvent('onclick',s_bc))s_wd.s_bcr=3D1}

else if(s_d.body & & s_d.body.addEventListener){if(!s_wd.s_bcr & &

s_d.body.addEventListener('click',s_bc,false))s_wd.s_bcr=3D1}else{var

ol=3Ds_wd.onload?s_wd.onload.toString():'';if(ol.indexOf( " s_wdl( " )<0){

s_wd.s_ol=3Ds_wd.onload;s_wd.onload=3Ds_wdl}}}}function s_iepf(i,a){if(

i.substring(0,1)!=3D'{')i=3D'{'+i+'}';if(s_d.body.isComponentInstalled(i,=

'ComponentID')){var n=3Ds_pl.length;s_pl[n]=3Dnew =

Object;s_pl[n].name=3Di

+':'+s_d.body.getComponentVersion(i,'ComponentID')}return 0}

function s_vs(un,x){var s=3Ds_gg('visitorSampling'),g=3Ds_gg(

'visitorSamplingGroup'),k=3D's_vsn_'+un+(g?'_'+g:''),n=3Ds_c_r(k),e=3D

new Date,y=3De.getYear();e.setYear(y+10+(y<1900?1900:0));if(s){s*=3D100

if(!n){if(!s_c_w(k,x,e))return 0;n=3Dx}if(n%10000>s)return 0}return 1}

function s_gs(un){un=3Dun.toLowerCase()

s_un=3Dun;var trk=3D1,tm=3Dnew Date,sed=3DMath & & Math.random?Math.floor(

Math.random()*10000000000000):tm.getTime(),sess=3D's'+Math.floor(

tm.getTime()/10800000)%10+sed,yr=3Dtm.getYear(),t,ta=3D'',q=3D'',qs=3D'';=

yr=3D

yr<1900?yr+1900:yr;t=3Dtm.getDate()+'/'+tm.getMonth()+'/'+yr+' '

+tm.getHours()+':'+tm.getMinutes()+':'+tm.getSeconds()+' '+tm.getDay()

+' '+tm.getTimezoneOffset();if(!s_q){var =

tfs=3Ds_gtfs(),tl=3Dtfs.location,

r=3Dtfs.document.referrer,s=3D'',c=3D'',v=3D'',p=3D'',bw=3D'',bh=3D'',j=3D=

'1.0',g=3D

s_wd.location,k=3Ds_c_w('s_cc','true',0)?'Y':'N',hp=3D'',ct=3D'',iepl=3Ds=

_gg(

'iePlugins'),pn=3D0,ps;if(s_apv>=3D4)s=3Dscreen.width+'x'+screen.height;i=

f(

s_isns||s_isopera){if(s_apv>=3D3){j=3D'1.1';v=3Ds_n.javaEnabled()?'Y':'N'=

if(s_apv>=3D4){j=3D'1.2';c=3Dscreen.pixelDepth;bw=3Ds_wd.innerWidth;bh=3D=

s_wd.innerHeight;if(s_apv>=3D4.06)j=3D'1.3'}}s_pl=3Ds_n.plugins}else if(

s_isie){if(s_apv>=3D4){v=3Ds_n.javaEnabled()?'Y':'N';j=3D'1.2';c=3D

screen.colorDepth;if(s_apv>=3D5){bw=3Ds_d.documentElement.offsetWidth;bh=3D=

s_d.documentElement.offsetHeight;j=3D'1.3';if(!s_ismac & & s_d.body){

s_d.body.addBehavior( " #default#homePage " );hp=3Ds_d.body.isHomePage(tl)?

" Y " : " N " ;s_d.body.addBehavior( " #default#clientCaps " );ct=3D

s_d.body.connectionType;if(iepl){s_pl=3Dnew Array;s_pt(iepl,',',s_iepf,

'');}}}}else r=3D'';if(!s_pl & & iepl)s_pl=3Ds_n.plugins}if(s_pl)while(pn<

s_pl.length & & pn<30){ps=3Ds_fl(s_pl[pn].name,100)+';';if(p.indexOf(ps)<0)

p+=3Dps;pn++}s_q=3D(g?' & g=3D'+s_ape(s_fl(g,255)):'')+(r?' & r=3D'+s_ape(s_f=

l(r,

255)):'')+(s?' & s=3D'+s_ape(s):'')+(c?' & c=3D'+s_ape©:'')+(j?' & j=3D'+j:''=

)+(

v?' & v=3D'+v:'')+(k?' & k=3D'+k:'')+(bw?' & bw=3D'+bw:'')+(bh?' & bh=3D'+bh:'')+=

(ct?

' & ct=3D'+s_ape(ct):'')+(hp?' & hp=3D'+hp:'')+(s_vb?' & vb=3D'+s_vb:'')+(p?' & p=

=3D'

+s_ape(p):'')}if(s_gg('usePlugins'))s_wd.s_doPlugins();q+=3D(t?' & t=3D'

+s_ape(t):'')+s_hav();if(s_lnk||s_eo){var o=3Ds_eo?s_eo:s_lnk;if(!o)

return '';var =

p=3Ds_wd.s_g_pageName,w=3D1,t=3Ds_ot(o),n=3Ds_oid(o),x=3Do.s_oidt,

h,l,i,oc;if(s_eo & & o=3D=3Ds_eo){while(o & & !n & & t!=3D'BODY'){o=3Do.parentElem=

ent?

o.parentElement:o.parentNode;if(!o)return =

'';t=3Ds_ot(o);n=3Ds_oid(o);x=3D

o.s_oidt}oc=3Do.onclick?o.onclick.toString():'';if(oc.indexOf( " s_gs( " )>=3D=

0)return =

''}ta=3Do.target;h=3Do.href?o.href:'';i=3Dh.indexOf('?');h=3Ds_gg(

'linkLeaveQueryString')||i<0?h:h.substring(0,i);l=3Ds_gg('linkName')?

s_gg('linkName'):s_ln(h);t=3Ds_gg('linkType')?s_gg('linkType'

).toLowerCase():s_lt(h);if(t & & (h||l))q+=3D' & pe=3Dlnk_'+(t=3D=3D'd'||t=3D=3D=

'e'?

s_ape(t):'o')+(h?' & pev1=3D'+s_ape(h):'')+(l?' & pev2=3D'+s_ape(l):'');else

trk=3D0;if(s_gg('trackInlineStats')){if(!p){p=3Ds_wd.location.href;w=3D0}=

p=3D

p?s_fl(p,255):'';t=3Ds_ot(o);i=3Do.sourceIndex;if(s_gg('objectID')){n=3D

s_gg('objectID');x=3D1;i=3D1}if(p & & n & & t)qs=3D' & pid=3D'+s_ape(p)+(w?' & pidt=

=3D'+w:

'')+' & oid=3D'+s_ape(n)+(x?' & oidt=3D'+x:'')+' & ot=3D'+s_ape(t)+(i?' & oi=3D'+=

i:'')

}s_wd.s_linkName=3Ds_wd.s_linkType=3Ds_wd.s_objectID=3Ds_lnk=3Ds_eo=3D'';=

if(

!s_wd.s_disableLegacyVars)s_wd.linkName=3Ds_wd.linkType=3Ds_wd.objectID=3D=

''

}if(!trk & & !qs)return '';var =

code=3D'';if(un){if(trk & & s_vs(un,sed))code+=3D

s_mr(un,sess,q+(qs?qs:s_rq(un)),ta);s_sq(un,trk?'':qs)}else if(

s_wd.s_unl)for(var unn=3D0;unn<s_wd.s_unl.length;unn++){un=3Ds_wd.s_unl[

unn];if(trk & & s_vs(un,sed))code+=3Ds_mr(un,sess,q+(qs?qs:s_rq(un)),ta)

s_sq(un,trk?'':qs)}return code}function s_dc(un){un=3Dun.toLowerCase()

s_wds(un);s_ca(un);return s_gs(un)}

------=_NextPart_000_0000_01C767AE.21D31300--

March 16, 2007