RE: Neurotransmitters and autism

[Guest guest]

Hello

The book doesnt give all the answers, just lots of clues and knowledge. I am reading lots of books all the time.

Most of the books I do not buy - you can request an inter-library loan from any library for £2.75 and borrow it for 6 weeks - thats what I do. I have 6 similar ones in the car!

Best wishes

Pweter

To: Autism-Biomedical-Europe From: ckannavil@...Date: Wed, 24 Nov 2010 09:50:54 +0000Subject: Re: Neurotransmitters and autism

Thanks a lot for such an invaluable in formation. As you said to find out which neurotransmitter causing the behaviour do we need to read the book you mentioned?. If it is so then i will order right away.As this seems as very important to know as parents. Thanks for your information.

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To: Autism-Biomedical-Europe Sent: Mon, 22 November, 2010 19:28:01Subject: Neurotransmitters and autism

Have just finished a 580 page book on this. A summary of what came out:There are 5 different kinds of neurotransmitters:1. classical synaptic (eg GABA, glutamate,glycine, acetylcholine, ATP)2. monoaminergic (eg dopamine, noradrenaline, adrenaline, histamine, serotonin, catchecholamines)3. neuropeptides4. classical released by different transport method5. gases (eg nitrous oxide, endocannabinoids)Every neurotransmitter can go wrong in 4 ways: not enough/ too much, poor transmission, poor receptor, poor transport.classical synaptic ones do all the fast work. all the others regulate the classical ones.all neurotransmitters are made from 4 protein typesneurotransmitters all have 5-10 different receptor channels. they are pumped it seems with calcium, sodium or hydrogen potentialsIf you have a symptom, eg not putting on weight, anxiety, lack of gastric acid secretion, no bladder feeling, no socialisation, not registering pain, cognition issues, you have a good chance of being able to pinpoint which neurotransmitter channels are blocked, as they all control these kind of behavioursToxins of all kinds block these channels, and are very specfic - for example a tetanus toxin blocks acetylcholine (muscle) receptors which is why muscles seize up. Havent learned everything here, but it seems if we want to address an issue, you can look up which neurotransmitter channel is not working (which controls this behaviour) then look at the 4 ways it could be going wrong, and associated toxins which can cause these - and then address the problemSource: "Pharmacology of Neurotransmitter release - Sudhof 2008"