80 - cancer

[Guest guest]

She's 80 and she has had a breast removed. Now the

cancer is spreading throughout her body. The doctor's

say that chemo is a must so as to avoid the pain. What

say you ?

Moses.

[Guest guest]

I know many people who have had great success with mgn-3. Here is a link for

the best price I have found. 41.70 a bottle at: ( mgn-3)

http://www.vitacost.com/index.html

And scroll down for a long article on it.

Donna

-----Original Message-----

She's 80 and she has had a breast removed. Now the

cancer is spreading throughout her body. The doctor's

say that chemo is a must so as to avoid the pain. What

say you ?

Moses.

A few short years ago, any comment about a substance's ability to boost

the immune system " would have brought howls of laughter and condemnation

from the medical community. Nowadays, however, this same concept seems

to be all the rage among both traditional and conventional medical

practitioners. Slowly but surely, modern medicine is beginning to

understand the vital importance of enhancing the body's own

disease-fighting capabilities.

MGN-3: Quite Possibly The Most Powerful Immune Booster Known to Man

The work of one particular doctor, Dr Mamdooh Ghoneum, is undoubtedly

going to awaken many in conventional medicine to the enormous benefits

of using natural immune-enhancing compounds. Dr Ghoneum works with the

Department of Immunology at Drew University in Los Angeles. For the last

six years he has been working on an amazing product called MGN-3. By

reading this issue, you are among the first to ever hear about it. In

fact, as far as I know, this is the first time the public has been told

about MGN-3. Up until this article, the only published information about

it has been buried in technical medical journals. When I first spoke

with Dr Ghoneum, I asked him why. His answer may surprise you, as it did

me.

Dr Ghoneum was educated in Egypt and Japan, and as I mentioned earlier

he continues to spend much of his time in those countries. His work with

MGN-3 began in Japan, where he is quite well-known. (He just finished

his sixth book in Japanese, all of which deal with cancer.) As with most

new therapies, his initial research was performed in vitro and later

using animal models. Although the results were extremely positive, he

refused to publicize the data until he was sure the similar results

could be duplicated in humans. In a world where new fads based on just

the slightest hint of benefit pop up almost daily, it's refreshing and

unusual to meet someone willing to forgo publicity in an effort to

perform actual human studies. For this, Dr Ghoneum is to be highly

commended.

Thanks to Dr Ghoneum, we now have excellent research data to show that =

MGN-3 is likely the most powerful human immune system booster on the =

market today, prescription or otherwise. Even most amazing is the fact =

that it has no known side effects. The implications this substance could =

have on your personal health are astounding.MGN-3 Combines a Potent =

Antiviral Extract with the Three Top Cancer Treatments in Japan MGN-3 is =

produced by integrating, through hydrolysis, an extract from the outer =

shell of rice bran with the extracts from three different mushrooms: =

Shiitake (yielding Lentinan), Kawaratake (yielding Krestin), and =

Suehirotake (yielding Sizofiran).

On their own, extracts from rice bran exhibit fairly strong antiviral =

effects. And extracts from each of these three mushrooms have been found =

to have anti-cancer properties. In fact, in Japan, these three mushroom =

extracts have become the three leading prescription treatments for =

cancer. In the years to come, I feel very strongly that mushrooms will =

become a primary source of natural medicines all over the world. Of the =

million or so known varieties, only a small handful have been =

categorized and analyzed. One of the challenges of using mushrooms =

medicinally is that they seem to work differently with different people. =

Fortunately, as I'll explain later, the benefits MGN-3 provides the =

immune system are very consistent and predictable.

Natural Killer Cells

The human immune system is comprised of more than 130 subsets of white =

blood cells. In order to understand just how powerful an immune =

stimulator MGN-3 is and how you can use it to help treat a wide variety =

of serious health problems, you need some background information on one =

of the most common forms of white blood cells.

Natural Killer (NK) cells make up roughly 15% of all human white blood =

cells. They provide the first line of defense for dealing with any form =

of invasion to the body,sort of like elite military soldiers who =

arcalled upon to seek out and destroy dangerous invaders. Each cell =

contains several small granules which act as " ammunition. " Once an NK =

cell has recognized a cancer cell, for example, it attaches itself to =

the cell's outer membrane and injects these granules directly into the =

interior of the cell. The granules then " explode, " destroying the cancer =

cell within five minutes. The undamaged NK cell then moves on to other =

cancer cells and repeats the process. When the immune system is =

particularly strong, active NK cells will often take on two cancer cells =

or other infected cells at the same time.

NK Activity, Not Volume, Determines the Strength of the Immune System

Unlike other white blood cells, inadequate numbers of NK cells are very =

rarely a problem. Instead, it is the activity of the cells that =

generally determines whether one is sick or healthy. As long as the NK =

cells are active (just soldiers remain on " active " duty, ready for =

battle), everything remains under control. If cells lose their ability =

to either recognize or destroy the invader, however, the situation can =

deteriorate rapidly. In AIDS and cancer patients, NK cell activity is =

probably the primary criteria for estimating the chances of survival.=20

It's pretty much accepted that when NK cells cease to function, the end =

is near. In addition, research has now confirmed that individuals with =

low NK cell activity are significantly more susceptible to autoimmune =

diseases, chronic fatigue immune dysfunction (CFIDS or chronic fatigue =

syndrome), viral infections and the development of cancerous tumors. (I =

haven't been able to verify that the same holds true in humans, but =

animal research has also shown that females commonly have lower NK cell =

activity than males.)

Doctors can test NK cell activity with a test called the NK cell

function test. Basically, a blood sample is taken from the patient and

placed in a vial containing live tumor cells. After four hours, a count

is taken to determine what percentage of the cancer cells have been

destroyed by the NK cells. The higher the percentage, the more active

the cells.

(Technically, the test is referred to as the 4 hour 51Chromium-release

assay. I'm certainly not advocating that everyone go out and have it

done, but if you have been dealing with one of the conditions listed

above or have had any sort of longstanding infection, it may be a good

idea. If your local lab doesn't perform the test, your doctor can order

it from Specialty Labs in Santa , CA at .

How MGN-3 Increases NK Cell Activity

MGN-3=3D92s ability to boost NK activity and overall immunity appears to =

stem from four things.

1) First, as I mentioned earlier, MGN-3 increases the number of =

explosive granules in NK cells. The more granules an NK cell carries, =

the more cancer and virus-infected cells it can destroy.

2) MGN-3 increases interferon levels. Interferon is another potent =

compound produced by the body that both inhibits the replication of =

viruses and other parasites and increases NK cell activity.

3) MGN-3 increases the formation of Tumor Necrosis Factors (TNFs). TNFs =

These are a group of proteins that help destroy cancer cells

4) In addition to increasing NK activity as much as 300% (or even =

higher), oral ingestion of MGN-3 can increase the activity of other key =

immune cells, like T-cells (200%) and B-cells (250%).

Dr Ghoneum's years of research have proven just how powerful MGN-3 can =

be at boosting NK cell activity and combating a wide range of diseases. =

The majority of his work has been with cancer patients.

Cancer

Unlike most forms of cancer treatment, MGN-3 is totally non-toxic. After =

years of use and continued toxicity tests, there have never been any =

indication of toxicity or side effects whatsoever. Undoubtedly, this is =

because MGN-3=3D92s primary function is to enhance the activity of the =

immune system rather than to attack cancer cells directly. This also =

helps explain why it seems to work well for all types of cancer. =

Although huge amounts of data haven't been published yet, MGN-3's =

effects on human cancer patients have been very promising.

Dr Ghoneum's latest study involved 24 cancer patients. First, doctors =

tested NK cell activity in each patient, and then administered the =

recommended cancer dosage of 3 grams per day of MGN-3. NK cell activity =

was tested again after 16 hours, one week, one month and two months.

After 16 hours, NK cell activity had increased 1.3 to 1.5 times. After =

one week, activity had increased eightfold. Activity continued to =

increase, and at the end of two months, the NK cells were killing 27 =

times more cancer cells in the four hour period than they were prior to =

take the MGN-3. (Int J Immunotherapy 98;XIV(2):89-99).

Research Shows That NK Activity Shoots Up Within Two Weeks and Continues =

To Rise Dr Ghoneum told me that over the years he's run numerous NK cell =

activity tests on patients with all types of cancers, and in 80 to 90% =

of those patients, their NK cells could only kill about 20 to 30% of the =

cancer cells during the first hour of the test. After just two weeks of =

taking MGN-3, however, the kill percentage jumped to 60 to 70% in 99% of =

the patients.

Dr Ghoneum presented the results from one of his studies involving five =

patients with breast cancer at the November 5, 1995, meeting of the =

American Association for Cancer Research. Each patient was treated with =

the same dosage of 3 grams per day of MGN-3. NK cell activity increased =

within two weeks and continued to do so as the study progressed. At the =

end of the six- to eight-month study, two of the patients were already =

in complete remission. Another study of Dr Ghoneum's involved 27 cancer =

patients ranging in age from 42 to 57. The types of cancers involved =

included breast, cervical, prostate, leukemia, and multiple myeloma. All =

patients had low NK cell activity at the beginning of the study. After =

only two weeks, the NK cell activity had increased as follows: breast =

carcinoma 154-332%, cervical carcinoma 100-275%, prostatic cancer =

174-385%, leukemia 100-24-%, and multiple myeloma 100-537%. Remember, =

this was after just two weeks of MGN-3, and NK activity continued to =

rise throughout the six-month study. (Study reported at the 87th Annual =

Meeting of the American Association for Cancer Research, April 20, =

1996.)

MGN-3 Helps Cancers That Are Unaffected by Angiogenesis Inhibitors MGN-3 =

fills a gap left by many of the other natural therapies we've covered in =

the past, in particular, the class of therapies known as angiogenesis =

inhibitors.

Angiogenesis inhibitors, as you may recall from previous issues, work by =

cutting off the blood supply to tumors. Whether they be natural products =

like shark cartilage or pharmaceutical ones like endostatin and =

angiostatin, these angiogenesis inhibitors aren’t very effective at =

treating blood cancers such as leukemia, lymphatic cancer or lung =

cancer. In each case, the explanation for this ineffectiveness is fairly =

simple.

Because leukemia is a cancer of the blood cells themselves, cutting off =

the blood supply to these cells is simply impossible. With lymphatic =

cancer, it’s the lymphatic fluids, not blood vessels, that supply =

lymph cells with all of their necessary nutrients, so again, cutting off =

the blood supply is futile. And because the lungs have such a rich and =

complex supply of blood vessels, there’s really no effective way to =

restrict blood flow to that area.

None of these factors pose a problem for MGN-3. By increasing the =

activity of NK cells, which naturally reside and circulate in the blood =

and lymph systems, MGN-3 can be used effectively for all of these =

cancers. The NK cells don/t have to penetrate deep into massive hard =

tumors to get to active cancer cells, they simply identify and =

eliminate the cancer cells they " encounter " in the blood or lymph.

MGN-3 Has Even Worked with Multiple Myeloma,

One of the Deadliest Cancers

In another study involving 11 patients, the percentages of patients =

experiencing complete remission with MGN-3 were as follows:

1) Prostate cancer, two of the three patients or 66%. (Note: All of the =

prostate patients experienced a decline in PSA levels. One reached a =

normal level after one month on MGN-3, another's was normal after two =

months and the third patient's dropped from 87.2 to 7 after four =

months.)

2) Ovarian cancer, two of the three patients or 66%

3) Breast cancer, one of the three patients or 33%. (The other two had =

partial remission.)

4) Multiple myeloma, one of the two patients or 50%. (Int J =

Immunotherapy 95;XI(I):23-28).

While all of these results are impressive to say the least, the case of =

the multiple myeloma patient is particularly remarkable. Multiple =

myeloma is a very rare and fatal cancer. It makes up only about one =

percent of all cancers, and among oncology circles, it is considered =

practically incurable. Without treatment, a patient almost always lives =

less than a year. With chemotherapy, some have been known to live two =

years.

The multiple myeloma patient who experienced complete remission was =

58-year-old male who was diagnosed in October of 1990. He first =

underwent several months of chemotherapy following his diagnosis. =

Although everything seemed to have stabilized, his laboratory work still =

showed specific blood markers for multiple myeloma eight months after =

the chemotherapy. He then began taking the MGN-3, and in less than six =

months follow-up, lab work revealed no indication of cancer. Today, =

almost eight years after his initial diagnosis, he continues to take =

MGN-3 and shows no signs of cancer. Dr Ghoneum told me that this is the =

first patient who has been known to survive multiple myeloma.

MGN-3 Lessens the Toxicity and Improves the Effectiveness Of =

Conventional Cancer Therapies

Above and beyond its own cancer-fighting abilities, MGN-3 lessens the =

toxic side effects of conventional cancer treatment. Both chemotherapy =

and radiation destroy many of the body's white blood cells in the =

process of trying to destroy the cancer. Taking MGN-3 concurrently with =

these treatments can help prevent this effect. Many chemotherapy =

patients taking MGN-3 have also reported experiencing less difficulty in =

swallowing and less burning of the tongue.

In addition, MGN-3 has been used effectively with interleukin-2, the =

only prescription item that seems to come close to matching its =

immune-boosting power. (Although there are other natural products that =

have immune-boosting capabilities, none have been proven in human =

studies to be more powerful than MGN-3.)

Interleukin is a protein that is normally produced in the body. Much =

like MGN-3, it also activates certain white blood cells. To potentiate =

the effects of this protein, scientists isolated and synthesized it into =

a chemical called interleukin-2 (IL-2). This extract is then injected =

into patients to help stimulate their immune systems.

Although IL-2 is gaining popularity as a cancer treatment, it can =

trigger extremely severe and life-threatening side effects. At the =

therapeutic doses used for cancer, interleukin-2 causes leaks in the =

small capillaries. These leaks result in a loss of blood pressure, =

weight gain, fluid retention, difficulty breathing and heart problems. =

Continued use can cause kidney failure, respiratory arrest and death. In =

this way, it represents yet another cancer treatment that often kills =

the patient before it kills the cancer. Expense is also a factor. A =

single interleukin-2 treatment can cost as much as $100,000.=3D

Dr Ghoneum's research has revealed that when MGN-3 is used along with =

interleukin-2, the dosages of interleukin-2 can be reduced to extremely =

low levels,levels which are low enough to avoid the severe side effects. =

When used together, these two products have a synergistic effect that =

dramatically exceeds that of either used individually. Once this =

knowledge becomes public (beyond this article, I mean), I hope more =

oncologists will be doing work in this area. I will personally be =

keeping a close eye on any additional research that develops and, as =

always, keep you informed in the months to come.

Pre-Cancerous Cells (Cervical Dysplasia)

Another of Dr Ghoneusm's studies involved seven female patients whose =

pap smears indicated the presence of abnormal cells. This is not an =

uncommon finding, and while these cells are not cancerous, they are =

often referred to as pre-cancerous because of their propensity to =

develop into cervical cancer.

The severity of cervical dysplasia, as the problem is termed medically, =

is classified in four stages depending on the degree of abnormality in =

the cells. Stage I is generally a " wait-and-watch " situation, stages II =

and III are considered surgical cases, and stage IV is considered =

cancer.

In the above study, Dr Ghoneum found that using MGN-3 is stage II and =

III patients completely resolved the problem. After six months of MGN-3 =

use, with no other form of treatment, all follow-up exams and tests were =

normal. Some of the women have continued on maintenance doses of MGN-3 =

at 1 gram per day. Others have discontinued its use. Today, two to three =

years after the study, none of the women has experienced recurrence, =

including women who discontinued the product after only six months.

(Over a decade ago, in Vol 1, No 21, I wrote about how high doses of =

folic acid (10 milligrams a day) could also be used for cervical =

dysplasia. I would certainly recommend following the guidelines I =

outlined in that issue, in addition to those I will outline for MGN-s, =

for treating such problems.)

HIV

Over the years, Dr Ghoneum has worked with several HIV-infected =

patients. During the normal progression of this disease, NK cell begins =

to drop along with other immune cells called CD4s and CD8s. CD4 levels =

routinely decrease at a rate of about 15% a year. In patients taking =

MGN-3 however, Dr Ghoneum says the CD4 levels can be maintained in =

almost every case, and oftentimes they will even begin to increase.

Work with AIDS patients has been limited, although all of the patients =

who have taken MGN-3 reported a noticeable difference in their =

well-being, and all have continued to use the product. Most felt MGN-3 =

was instrumental in helping them stabilize their disease.

Although laboratory work has confirmed that MGN-3 inhibits the =

replication of HIV, it is definitely not the total answer to the =

problem. Over the years, I have reported on a number of therapies that =

seem to ameliorate the effects of the virus, but it remains clear that =

more research needs to be done in this area. (Biochem Biophys Res Commun =

98;243:25-29).

Hepatitis

Although he has not yet published the results, Dr Ghoneum recently =

shared with me his extraordinary results using MGN-3 to treat viral =

hepatitis, varieties B and C.

Within one week to a month of taking the product, all of the patients =

had experienced a significant decrease in their symptoms. Laboratory =

tests for enzyme levels have shown that liver function begins to improve =

within two weeks. And after four to five months, everything shows up as =

normal. Dr Ghoneum has been following one particular hepatitis patient =

for almost two years now, and the patient has not experienced any =

relapse nor any further problems. The patient continues to take the =

daily maintenance dosage of the MGN-3 (1 gram per day).

Additional Therapeutic and Preventive Applications for MGN-3

Dr Ghoneum has performed an amazing amount of valuable research in just =

the last six or seven years. When I last spoke with him, he expressed =

eagerness to investigate MGN-3's therapeutic potential with many other =

conditions, but in light of his limited time and research funding, he's =

had to concentrate his efforts on life-saving areas like cancer and =

AIDS. Based on what he has already uncovered, however, it is clear that =

his product holds great promise for many other conditions.

Earlier, I cited chronic fatigue syndrome as one of those conditions. =

Additionally, MGN-3 could prove to be a lifesaver when it comes to any =

chronic or severe bacterial, viral or fungal infection.

Dr Ghoneum has defined what he calls " high risk " categories, and he =

believes that individuals in these categories could also benefit from =

MGN-3 mainly as a form of disease prevention.Included in these would be:

Heavy smokers (those smoking two packs or more per day.

Heavy drinkers

Individuals who constantly work with paint (artists, house =

painters, etc)

Individuals born with immune deficiencies

Families with a strong history of cancer

Chemical and refinery workers

Dosages

The dosages Dr Ghoneum has used in his studies are scientifically based =

on repeated NK cell activity tests. As such, they are very consistent =

and easy to follow. They fall into two categories.

1) For cancer, HIV or other life-threatening condition, 3 grams per day =

for two weeks, then 1 gram per day until the problem is resolved. Some =

of the people Dr Ghoneum has worked with continue to take the =

maintenance dosage even after the problem has been resolved, while =

others stop taking it and resume if the problem returns.

2) As a form of prevention, 1 gram per day.

Just to reiterate, MGN-3 is completely non-toxic and there's no danger =

whatsoever in taking it long-term. Many people stay on it for life In =

all of his studies, Dr Ghoneum found that taking 3 grams a day resulted =

in a dramatic increase in NK cell activity within one to two weeks. At =

the lower dosage of only 1 gram per day, the same activity wasn't =

reached until about four weeks. This explains the initial heavy doses of =

3 grams per day. Even after the dosage is dropped back to 1 gram per =

day, NK cell activity will continue to increase.It is best to take the =

MGN-3 capsules with meals in divided doses. For example, when taking 3 =

grams a day (which works out to 12 capsules), 4 capsules can be taken =

with each meal. When you drop down to 1 gram a day (4 capsules), you can =

take two capsules at breakfast and two at dinner.

Product Availability

In the United States, MGN-3 is marketed exclusively by Lane Labs and is =

available through select distributors of quality vitamins and natural =

supplements.The price of this product is on the expensive side compared =

to ordinary supplements, but certainly not compared to prescription =

medications or treatments.

(A 50-capsule bottle (250 milligrams per capsule) has a retail price of =

$62.95, (See link at beginning of post for best price around $41.70)

MGN-3's Role in the Treatment of Cancer

Based on his research and experience, I asked Dr Ghoneum for his =

opinions on the treatment of cancer and what he would do if he were =

diagnosed with the disease. (I would like to acknowledge up front that =

Dr Ghoneum shared the following terrorist analogy with me prior to the =

US military taking action against terrorists in the Middle East. While I =

considered removing this section for " political " reasons, the fact =

remains that the analogy works, and I want you to read it just as Dr =

Ghoneum explained it to me.)

Depending on the type and location of the cancer, Dr Ghoneum believes =

that surgery or a few cycles of chemotherapy or radiation therapy would =

be justified. He compared treating cancer to trying to wipe out a city =

of terrorists. By bombing the city, you would likely take care of the =

majority of the terrorists, accepting the fact that some non-terrorists =

would also be killed. Chemotherapy, radiation or surgical removal of the =

tumor are the cancer-equivalents of the bombing, and the beneficial =

white blood cells in the area are the non-terrorist victims.

Even after the bombing, however, there would always be some terrorists =

who could survive. The same holds true for cancer cells that were =

resistant to or able to survive the therapy. But rather than bomb the =

city again, which would only result in total destruction, special forces =

should be sent in to locate and eliminate the remaining terrorists one =

by one. This is where MGN-3 comes in. Dr Ghoneum feels that after =

surgery or a minimal number of chemo or radiation treatments, MGN-3 =

should be used exclusively to activate the immune system and let it do =

its work. (He also clarified that he would begin using the MGN-3 at the =

very first sign of any type of cancer, not just after conventional =

treatments had been completed.)

Dr Ghoneum had some strong opinions regarding the use of any drugs or =

nutritional products during the treatment period. For all of the people =

he's worked with, he recommended that only necessary prescription drugs =

be continued (such as those for diabetes, high blood pressure, thyroid, =

etc). In addition, because his research did not examine the combined =

effects of nutritional supplements and MGN-3, he recommended that =

patients concentrate on getting vitamins and minerals solely from =

natural foods and juices (organic carrots and other freshly made fruit =

and vegetable juices).

Through his work with the immune system, Dr Ghoneum has also found that =

poor sleeping habits and unresolved stress have a major negative impact =

on the activity of NK cells. He felt very strongly that both of these =

problems must be addressed if one expects to strengthen the immune =

system. (It was just last month that we revisited the importance of =

proper sleep in this newsletter. If you haven't taken the seven steps =

that I outlined, you may want to make that tonight's bedside reading.) =

This Is One of the Most Important Discoveries I've Shared with You in =

Our 13 Years Together

In many of these regards, I agree with Dr Ghoneum. If diagnosed with

cancer, I too would begin a diet largely comprised of fresh juices and

would make extra efforts to reduce the amount of stress in my life. I

would also begin taking MGN-3 immediately.

However, I cannot say that I endorse the use of chemotherapy and

radiation. I have met people who have been helped by it, and I have

watched others waste away because of it. Nor can I say that I would

cease taking nutritional supplements. It is more likely that I would

increase my intake of particular nutrients and, depending on the type of

cancer, begin taking cancer-specific supplements like shark cartilage.

The discovery of MGN-3 comes at a time when we need it most. Our health =

is under assault from practically every angle these days, and we now =

know that our best defense is to boost the inner workings of the immune =

system. MGN-3 gives us a safe and effective way of doing just that. It =

is the most powerful immune stimulant man has uncovered thus far, and it =

may be our best hope in conquering the world's deadliest diseases.

Dr

Dr has dedicated his life to conducting first-hand

research around the world on promising new therapies such as MGN-3. He

is the editor of a monthly newsletter published since 1985 that brings

to consumers and medical professionals the most up-to-date research on

safe and effective therapies for a wide range of health conditions.