aseptic meningitis on subQ Hizentra

[Guest guest]

Some of you may recall that my son, , 9, has had problems with the Hizentra

since he switched (from Vivaglobin) in the Spring. We have done tons of premeds

to reduce his side effects. He has had chronic migraines and we think that his

extreme leg pains and behavior changes are all due to the Hizentra also. Now,

he has been in the hospital with full-blown aseptic meningitis (diagnosed with

spinal tap). So, after being off meds long enough to return to baseline

behavior, no headaches or other pains, etc., now home--he received his first

dose of subcutaneous 10% Gammagard this morning--4 grams over 2 hours--and

reacted within 25 minutes of the end of the infusion.

Next week, we are talking about doing the infusion overnight, very slowly,

probably as our only other option. Anyone else experience aseptic meningitis

with SUBCUTANEOUS immune globulin?? What did you do to counteract it? any

other suggestions? I am at wit's end here.

Many thanks,

Mindy, in Virginia

mom to , 9, CVID, mostly nonverbal autism, mitochondrial disease