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Bloodwork results-help! Ursula and all

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It's been a while since my last post here regarding my son, , and I hope

although its Easter break, I am able to get some responses asap.

s past diagnosis was transient CVID, when around 4 yo, and by 6yo had

moved on to Absolute IgA deficiency and queried Selective Antibody deficiency

(dependent on which immunologist interpreted results) and he has been on

prophylactic abx for many years.

7 weeks ago , now 14yo, was hospitalised for upper right ab pain,

subsequent u/s only found slightly bulky spleen but liver, pancreas etc looked

fine. Bloodwork came back neutropenic and showed increased bilirubin. CT with

contrast found bilateral medullary sponge kidneys with calcification but no

issues with gallbladder, pancreas etc.

Two weeks past with pain abaiting to perhaps 2/10, and not rising above 4/10.

When it jumped to 8/10, this time with nausea, we made the drive to the

childrens hospital 3 hours away and he was admitted for 10 days. The only

testing done was endoscopy with biopsies, this due to query of gastritis due to

long term NSAID and GERD. Aside from mucin depletion of stomach lining, I

understand nothing untoward was found. Two days after discharge, was

readmitted to our local country hospital for pain relief with pain up at 8/10

and vomitting. He is looking brighter today and has been discharged to spend

Easter at home.

So here is my query, and I am sorry for the very long post. Immunology hopped

on board while was in the childrens hospital and re-ran testing that

hadnt been done in years. I have been unimpressed with the team in the past and

would like some feedback on what the following numbers may be indicating please,

before I next speak with them.

IgG 5.6 (6.1-13.0)

IgA <0.07 (0.69-3.10)

IgM 1.11 ((0.53-3.32)

subclasses:

IgG1 3.86 (3.70-12.80)

IgG2 1.21 (1.06-6.10)

IgG3 0.17 (0.18-1.63)

IgG4 0.70 (<2.31)

Lymphocyte count 1.8 (1.5-5.0 x10*9/L)

CD3 (T Cells) 61 (58-76%)

CD4 (CD4+TCells) 39 (30-52%)

CD8 (CD8+TCells) 20 (18-40%)

CD8 Absolute Count 360 (400-1300 x10*6/L)

Pneumococcal IgG2 Antibody <1 (mg/L)

Any feedback is hugely appreciated.

,

mum to and

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