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Chronic Urticaria Index

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Hello All,

I seemed to spark a big debate about vaccines last time I posted! So, I will

try something less controversial this time! :-)My 5 year old just got blookwork

back and I won't be able to talk to the doc until Monday due to the T-day

holiday. His CU Index (Chronic Urticaria) index was 40.9. The reference range

is <10. The statement on the lab work next to this value says " The CU Index tst

is the second generation Functional Anti-FcER test. Patients with a CU Index

>or = 10 have basophil reactive factors in their serum which supports an

autoimmune basis for disease. "

Is this saying that he has an autoimmune disease? And if so, which one?

Because his ANA screen was negative, his Adrenal, Thyroid and Rheumatoid factor

came back all within normal limits. Does anyone have any experience with

interpreting the CU Index? I seem to be getting more confused just by searching

the internet.

Other findings in his bloodwork are high IgE 529 in range of <60), High

Eosinophils (700 in range of 0-400), Low IgG Subclass 4 (.6 in ref range of

..8-81.9) and low natural killer cells (74 in range of 130-720).

Thanks Kim

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I looked this up earlier in the week, and all I got from it is that he has

CU--chronic urticaria. It looked autoimmune, like he has developed

antibodies to his own IgE and it resulted in the CU--as oppposed to an

allergic-type response kind of urticaria. Treatment is probably

different. But I haven't had time to go back and look at it. Sorry I

don't have much to add ;) My personal experiences with urticaria did turn

out to be allergy. Hope you find out more on Monday.

Mindy, mom to seven special kids

>

> Hello All,

>

>

>

>

>

>

> I seemed to spark a big debate about vaccines last time I posted! So, I

> will try something less controversial this time! :-)My 5 year old just

> got blookwork back and I won't be able to talk to the doc until Monday

> due to the T-day holiday. His CU Index (Chronic Urticaria) index was

> 40.9. The reference range is <10. The statement on the lab work next

> to this value says " The CU Index tst is the second generation Functional

> Anti-FcER test. Patients with a CU Index >or = 10 have basophil

> reactive factors in their serum which supports an autoimmune basis for

> disease. "

> Is this saying that he has an autoimmune disease? And if so, which one?

> Because his ANA screen was negative, his Adrenal, Thyroid and Rheumatoid

> factor came back all within normal limits. Does anyone have any

> experience with interpreting the CU Index? I seem to be getting more

> confused just by searching the internet.

> Other findings in his bloodwork are high IgE 529 in range of <60), High

> Eosinophils (700 in range of 0-400), Low IgG Subclass 4 (.6 in ref range

> of .8-81.9) and low natural killer cells (74 in range of 130-720).

> Thanks Kim

>

>

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