Fwd: Fw: HIV Treatment Bulletin: March/April 2012 - Volume 14 Number 3/4

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Dear Subscriber

Attached to this email is the HIV

Treatment Bulletin [HTB], Volume 14, Number 3/4. March/April

2012.

The online version is available at http://i-base.info/htb/date/2012/04

This edition of HTB will include as a

supplement the April 2012 update to Introduction to Combination

Therapy. 

This will be included in a second email

next week, so as not to include too many attachments in one

mailing.

Editorial

Volume

13 Number 3/4 March/April 2012

Special reports

Supplement:

i-Base Introduction to Combination Therapy

Conference reports

19th

Conference on Retroviruses and Opportunistic Infections (CROI), 5–8

March 2012, Seattle

Cure

research takes centre stage: proof of concept for activating the latent

reservoir

Quad

fixed-dose integrase combination: phase 3 studies at week

48

Dolutegravir

studies continue to show promise

Tenofovir

prodrug: 10 day monotherapy study sets dose at 25 mg for easier

coformulation

Paediatric

formulations of ARVs: including an exciting new class

Lower

malaria risk in children receiving lopinavir/ritonavir-based compared to

NNRTI-based ART

High

prevalence of d4T-associated lipodystrophy including lipoatrophy in

children

Lopinavir/ritonavir

monotherapy in children

Stopping

treatment after early ART in infants

PrEP:

PK modeling of daily TDF/FTC (Truvada) provides close to 100% protection

against HIV infection

Risk

of HIV reinfection may be similar to risk of initial HIV

infection

Case

report: homozygous CCR5 delta-32 protection overcome by infection with X4

virus

No

association between atazanavir and MI or stroke in D:A:D

study

Hepatitis

C coinfection studies

Herpes

Zoster vaccine safe and effective in HIV positive people

High

dose flu vaccine improves antibody responses in HIV positive

people

Antiretrovirals

Dolutegravir

Expanded Access Programme

FDA

approves etravirine for treatment-experienced children 6 to 18 years of age

and new scored 25 mg tablet for paediatric dosing

Guidelines

US

HHS adult treatment guidelines updated (March 2012)

Side effects

FDA

reject capsaicin patch for HIV-related neuropathy

PK and drug

interactions

FDA

warning of drug interactions between boceprevir and some HIV protease

inhibitors

Treatment access

Global

action over the challenge to India’s patent laws

Why

global health activists are fired up about Novartis

Obama’s

global, domestic & HIV research budget backslides on existing

commitments

Other news

Free

comic book for HIV positive children about CD4, viral load and ARV

treatment

On the web

Free

full text online articles

PDFs

Volume

13 Number 3/4 March/April 2012 PDF

 

Introduction to combination

therapy June 2010 [830 Kb] http://i-base.info/guides/starting

Guide to changing treatment and

drug resistance February 2011 [780Kb] http://i-base.info/guides/changing

HIV and your quality of life: a guide to

side effects and other complications December 2010 [1.2Mb] http://i-base.info/guides/side

Guide to HIV, pregnancy

& women’s health September 2011 (1.1 Mb) http://i-base.info/guides/pregnancy

Hepatitis C for people

living with HIV March 2009 [887 Kb] http://i-base.info/guides/hepc

HIV testing and sexual transmission

http://i-base.info/guides/testing

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