Fw: NATAP/CROI: 59% Minor Neuro Impairment in Asymptomatic HIV+

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Finally, we are starting to see Sustiva ( one of the medications in Atripla)

being linked to cognitive impairment. Many feel like they have a cloud in their

brains

Prevalence (59%) and Correlates of Minor Neurocognitive Disorders in Asymptomatic HIV-infected

Outpatients - see attached full poster report

 

Reported by Jules Levin, CROI 2010 Feb 16-19 SF

 

tta Ciccarelli1,2,

Massimiliano Fabbiani1, Simona Di Giambenedetto1, Iuri Fanti1, a

Colafigli1, Bracciale1, Enrica Tamburrini1, o Cauda1, De

Luca1,3*, Caterina Silveri2. 1Institute of Clinical

Infectious Diseases, Catholic University of Sacred Heart, Rome, Italy; 2Memory

Clinic, Catholic University of Sacred Heart, Rome, Italy; 3Infectious Diseases

Unit, Siena University Hospital, Italy. Corresponding Author: *Dr. De Luca, Email:

andrea.deluca@..., Tel. +390630154945, Fax. +39063054519.

 

AUTHOR CONCLUSIONS

- High prevalence of minor

cognitive disorders was observed in apparently asymptomatic HIV+ individuals.

- Cognitive impairment was

associated with lower CD4 cells count nadir and efavirenz use.

- In this cross-sectional

study, no association between CPE rank and cognitive impairment was observed,

even after excluding patients receiving efavirenz.

- Neuropsychological

investigation is important in the long term management of HIV+ patients.