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> Sunday, August 20, 2006 10:26 AM CDT

>

> FDA approves viruses for treating food

>

> By Associated Press

> WASHINGTON, D.C. -- A mix of bacteria-killing

> viruses can be safely sprayed

> on cold cuts, hot dogs and sausages to combat common

> microbes that kill

> hundreds of people a year, federal health officials

> said Friday in granting the

> first-ever approval of viruses as a food additive.

>

> The combination of six viruses is designed to be

> sprayed on ready-to-eat

> meat and poultry products, including sliced ham and

> turkey, said Vazzana,

> president and chief executive officer of

> manufacturer Intralytix Inc.

>

> The special viruses called bacteriophages are meant

> to kill strains of the

> Listeria monocytogenes bacterium, the Food and Drug

> Administration said in

> declaring it safe to use on ready-to-eat meats

> prior to their packaging.

>

> The viruses are the first to win FDA approval for

> use as a food additive,

> said Zajac, of the regulatory agency's

> office of food additive safety.

>

> The bacterium the viruses target can cause a

> serious infection called

> listeriosis, primarily in pregnant women, newborns

> and adults with weakened immune

> systems. In the United States, an estimated 2,500

> people become seriously ill

> with listeriosis each year, according to the

> Centers for Disease Control and

> Prevention. Of those, 500 die.

>

> Luncheon meats are particularly vulnerable to

> Listeria since once purchased,

> they typically aren't cooked or reheated, which can

> kill harmful bacteria

> like Listeria, Zajac said.

>

> The preparation of bacteriophages - the name is

> Greek for " bacteria-eater " -

> attacks only strains of the Listeria bacterium and

> not human or plant cells,

> the FDA said.

>

> " As long as it used in accordance with the

> regulations, we have concluded

> it's safe, " Zajac said. People normally come into

> contact with phages through

> food, water and the environment, and they are found

> in our digestive tracts,

> the FDA said.

>

> Consumers won't be aware that meat and poultry

> products have been treated

> with the spray, Zajac added. The Department of

> Agriculture will regulate the

> actual use of the product.

>

> The viruses are grown in a preparation of the very

> bacteria they kill, and

> then purified. The FDA had concerns that the virus

> preparation potentially

> could contain toxic residues associated with the

> bacteria. However, testing did

> not reveal the presence of such residues, which in

> small quantities likely

> wouldn't cause health problems anyway, the FDA

> said.

>

> " The FDA is applying one of the toughest food-safety

> standards which they

> have to find this is safe, " said Caroline

> DeWaal, director of food safety

> for the Center for Science in the Public Interest, a

> consumer advocacy

> group. " They couldn't approve this product if they

> had questions about its safety. "

>

> Intralytix, based in Baltimore, first petitioned the

> FDA in 2002 to allow

> the viruses to be used as a food additive. It has

> since licensed the product to

> a multinational company, which intends to market it

> worldwide, said

> Intralytix president Vazzana. He declined to name

> the company but said he expected it

> to announce its plans within weeks or months.

>

> Intralytix also plans to seek FDA approval for

> another bacteriophage product

> to kill E. coli bacteria on beef before it is

> ground, Vazzana said.

>

> Scientists have long studied bacteriophages as a

> bacteria-fighting

> alternative to antibiotics.

>

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