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Re: Bone changes

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Jeff,

All good questions, but without answers. Classically, the origins of

osteoporosis and osteonecrosis are entirely different. The first is over

activity of bone remodeling cells, the second a problem with blood supply.

At the same time, I'm asking myself the same question: Perhaps if the erosion

of bone goes to a certain point, perhaps the scaffolding of the bone begins to

collapse, compromising the blood vessels, and reducing the blood supply. Just

speculation, but you have to wonder.

I am on tenofovir, but have already done testing to see if I am a Maviroc

candidate.

I don't see any harm with getting a DEXA now, but as you know, before 50, nobody

really knows what it means........but on the same time, we've all seen plenty of

men in their 40s with hip fractures.

JB

On Oct 1, 2010, at 12:49 PM, Jeff wrote:

> Fascinating, if disturbing. Are you on tenofovir? Odd that it's localized in

the hip--do they think it's a precursor to AVN? We'll see what they have to say

at the aging conference in Baltimore next week. Good to see that they've

updated the guidelines to start screening at 50 in HIV+ men, though wondering if

I should get it now (48)

>

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