Re: native remedies response

[Guest guest]

good to hear - I'm sure a good year awaits

PS some info for anyone interested from native remedies re: seratonin

syndrome and FDA questions I asked them

Hi Eileen

Thank you for your query. Serotonin toxicity is an iatrogenic

<http://en.wikipedia.org/wiki/Iatrogenic> (i.e. caused by medical

treatment) toxidrome

<http://en.wikipedia.org/wiki/Toxidrome> . It is commonly referred to

as serotonin syndrome.

However, that is less than satisfactory terminology, because it is a

form of poisoning

<http://en.wikipedia.org/wiki/Poison> .[1]

<http://en.wikipedia.org/wiki/Serotonin_syndrome#_note-0>

The term toxidrome (from toxic <http://en.wikipedia.org/wiki/Toxic> +

syndrome

<http://en.wikipedia.org/wiki/Syndrome> ) is more appropriate and accurate.

Serotonin syndrome is caused by increased serotonin

<http://en.wikipedia.org/wiki/Serotonin> in the

central nervous <http://en.wikipedia.org/wiki/Central_nervous_system>

system usually as a result of

therapeutic drug use, intentional self-poisoning, or inadvertent

interactions between drugs. These

changes are more pronounced following supra-therapeutic doses and

overdoses, and they merge in a

continuum with the toxic effects.

Symptoms may be classed into three groups:

* Cognitive <http://en.wikipedia.org/wiki/Cognitive> effects:

mental confusion

<http://en.wikipedia.org/wiki/Mental_confusion> , hypomania

<http://en.wikipedia.org/wiki/Hypomania>

, hallucinations <http://en.wikipedia.org/wiki/Hallucinations> , agitation

<http://en.wikipedia.org/wiki/Agitation_%28emotion%29> , headache

<http://en.wikipedia.org/wiki/Headache> , coma

<http://en.wikipedia.org/wiki/Coma> .

* Autonomic

<http://en.wikipedia.org/wiki/Autonomic_nervous_system> effects:

shivering

<http://en.wikipedia.org/wiki/Shivering> , sweating

<http://en.wikipedia.org/wiki/Sweating> , fever

<http://en.wikipedia.org/wiki/Fever> , hypertension

<http://en.wikipedia.org/wiki/Hypertension> ,

tachycardia <http://en.wikipedia.org/wiki/Tachycardia> , nausea

<http://en.wikipedia.org/wiki/Nausea> , diarrhea

<http://en.wikipedia.org/wiki/Diarrhea> .

* Somatic

<http://en.wikipedia.org/wiki/Somatic_nervous_system> effects: myoclonus

<http://en.wikipedia.org/wiki/Myoclonus> /clonus

<http://en.wikipedia.org/wiki/Clonus> (muscle

twitching), hyperreflexia <http://en.wikipedia.org/wiki/Hyperreflexia>

, tremor

<http://en.wikipedia.org/wiki/Tremor> .

Insomnia <http://en.wikipedia.org/wiki/Insomnia> , sleep disruption,

and unrefreshing sleep are also

reported symptoms, as well as itching and

The combination of MAOIs <http://en.wikipedia.org/wiki/MAOI> and

other serotonin agonists or

precursors poses a particularly severe risk of a life-threatening

serotonin syndrome episode. Many

MAOIs <http://en.wikipedia.org/wiki/MAOI> inhibit monoamine oxidase

irreversibly, so that the

enzyme cannot function until it has been replaced by the body, which

can take at least two weeks. A

dangerous serotonin syndrome reaction can occur unless serotonin

agonists and even serotonin

precursors such as foods containing tryptophan are strictly avoided

until the monoamine oxidase has

been replaced.

Treatment

There is no antidote to the condition itself, but emergency medical

clinicians can administer

cyproheptadine <http://en.wikipedia.org/wiki/Cyproheptadine> or methysergide

<http://en.wikipedia.org/wiki/Methysergide> to control the symptoms.

Doing so is important as the

symptoms can in severe cases be potentially life threatening.

If the symptoms are not severe or life threatening, optimal treatment

consists of discontinuation of

the offending medication or medications, offering supportive measures,

and waiting for the symptoms

to resolve. If the offending medication is discontinued, the condition

will often resolve on its own

within 24 hours.

Unfortunately, the FDA does not approve or validate herbal or

homeopathic remedies, nor require

double blind or other such testing. They do inspect them as they enter

the country to ensure that

there are no problems, but this is not the same as their approval

process for medicines.

However, Native Remedies, as a company, is registered with the FDA ,

as are the manufacturers and

the formulator of all the remedies. You can therefore be assured that

all our products are of the

highest quality and formulated under pharmaceutical conditions to the

correct therapeutic strength.

For more info, please go to:

Native <http://www.nativeremedies.com/> Remedies

Please let us know if there is anything else we can assist you with.

Warm regards,

Quoting McRobie <ocdisordermom@...>:

> Here's to a peaceful and hopeful new year! I am grateful to this

> group for being here, for sharing the highs and the lows, the

> uncertainties and the fears, for your candor about the sheer

> intensity of the experiences and for your wealth of information.

> And for the sincere, generous, human support. Thank you, one and all.

>

> I felt as if I went into the holiday season holding my breath. It

> was last year at this time that , then 10, pretty much lost

> control of her OCD and starting staying up late at night ritualizing

> and out of desperation we sought out medication. So I was fearful

> of how the holidays would be this year. Since she lost the benefits

> of Zoloft suddenly in late August, after about five months of

> pretty good response, and didn't respond to trials of Lexapro or

> Anafranil this fall, I figured we would have another Christmas like

> last year's. She had been taking 20 minutes to walk through a room

> at home, at least 10 minutes to get out of the car, and on and on.

> So I didn't get tickets for anything like the Nutcracker - I

> figured we'd never make it to the theater in time!

>

> And what happened (huge exhale!) has been Abilify, She worked up to

> 6 mg about a week ago. Now can spontaneously leave the

> house, goes to bed because she's tired, hasn't had a shouting match

> in a week, takes shorter showers, walks through the house without

> incident! She's still tapping things, still has repetitive

> behaviors, but BOY what a change! The most interesting change is

> that she's letting me talk to her just a little about OCD. She has

> NEVER been forthcoming about what she feels, what's going on in her

> thoughts, etc. Now, when I coax her a bit, she'll actually say

> something that confirms that she knows she has this disorder. Not a

> lot, but it's a start. It must be the Abilify. She's also a

> little more zombie-like than I want her to be, but we need to see

> what difference this makes when she goes back to school next week.

>

> I fear for her, of course. She can't possibly take this stuff

> forever - first, it's just plain too expensive. Second, she

> probably wants to do " normal " stuff like having kids, and you can't

> take all of these chemicals when pregnant (I know, she's only 11,

> but I have to think about her future!). I want so badly to have her

> in ERP, which of course may not be compatible with Abilify (no

> strong compulsions to work with while medicated). But for now,

> we'll take what we've got and relax a bit as she gets the benefit of

> being freed, however temporarily, from some of her rituals.

>

> Without this group, I never would have known about the kids who have

> gotten benefits from Abilify (the psychiatrist wanted to try

> Seroquel next and it might have worked, who knows?). I asked for it

> because many of you had shared positive experiences. So my thanks

> to you. And we'll see what happens.

>

> Again, a Happy New Year as we work to make our kids' futures brighter.

>

> Cheers,

>

>

> __________________________________________________

>