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Re: Rogena--eosinophils

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HI,

We are very familiar with eosinophilic disease, as too many

eosinophils in 4 organs is the heart of my daughter's autoimmune

disease. We saw the group in Cincinnati that specializes in the GI

disease for 2 years. They had said if the eosinophils are lower in

the GI tract than the esophagus, it is likely an autoimmune

response, that will not usually respond to the more allergic

treatments, such as food removals, or allergy meds. They have not

found singulair to be as effective as they hoped, and singulair is

tied to a serious disease called Churg-Strauss. For disease in the

colon they usually have treat with a topical steroid called

bechlomethasone, or Entocort. You do not absorb this steroid as you

would prednisone, you only absorb about 30% of the dose

systemically, therefore you don't have as many side effects. The drs

in CIncinnati told me that reactions in the colon they do not think

are from food allergy. Mnay of the kids they treat have as your son

with their esophagus and either the colon or stomach. In these cases

they say it is a mixed reaction, of allergy and autoimmune, so food

removal of allergens and a drug to treat the colon are usually what

they recommend. I don't want to throw too much at you, or tell you

to be questioning your dr, but this is a fairly rare disease that is

very frequently not diagnosed or treated correctly. I hope singulair

alone will do wonders, but if you see it not helping you may wnat to

do a little research, and have your dr. The site for the American

Partnership for Eosinophilic Disorders has a great site about the

common tests and treatments that is very informative. It is

www.apfed.org. Hope your son is feeling better soon.

-- In , " megoonie99 " <megoonie99@...> wrote:

>

> Well, we got the results of 's biopsies 2 days earlier than I

had

> anticipated! He had high concentrations of eosinophils in his

> esophagus and colon. Hopefully this is the reason for his pain. The

> dr. bumped him up to 10mg singulair (he's been on 5mg for 4 years)

and

> I need to call in 2 weeks to update them on how he is or sooner if

> there are problems.

>

> I could kick myself for this one---in August at the pulmo appt.,

the

> dr. talked me out of food allergy testing (which I requested, so I

had

> them off their allergy meds for the week--what a DRAG--we were ALL

> miserable that week!). But when we saw the GI later in the month,

I

> said what happened, and he was surprised that the pulmo said that

> because 's tests were 4 years old. BUT, the GI did say that

he

> can order the RAST tests if the need ever comes up. So, do we now

> need to do RAST testing with him to see if he is any more allergic

to

> the foods and/or other things he was before and any new ones? As

a

> baby he was lactose intolerant, but seemed to get over that ....

I

> guess along with every answer comes even more questions.

>

> Thanks for putting up with me!

>

> Have a great day!

> Meg

>

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Thank you, . I appreciate the info. I think it is still

sinking in, and from what i am reading, it is kinda rare. That kind

of surprises me because they picked up on it so quickly, to me

(granted, he has been complaining of the lower abdomenal pain for

almost 9 yrs and he just turned 11--once I got someone to listen to

me, then it was quick to find). I read something that some dr's at

the Cleveland Clinic children's hosp. had done. My oldest goes to

the Clinic for his growth hormone def.

The website you mentioned, i had found earlier today. It had some

good info!! Anything and everything else you can tell me about this

would be greatly appreciated! I don't know what to think at this

point. He has been on singulair for his asthma/allergies for 4

years. I read where the jury is out on the effectiveness of

singulair for treatment. I really like this GI, and that they

called so fast to get his dose increased impresses me. I feel like

this guy is on top of things, at least right now. He was the only

one who took this all seriously from the first visit. I just got

pissed at the first GI and refused to go back and see him. In

August, the good GI asked if eosinophils had been checked. I was

clueless as to what that meant. I still am basically clueless, but

I am reading, reading, reading!!!

Thanks!

Meg

> >

> > Well, we got the results of 's biopsies 2 days earlier than

I

> had

> > anticipated! He had high concentrations of eosinophils in his

> > esophagus and colon. Hopefully this is the reason for his pain.

The

> > dr. bumped him up to 10mg singulair (he's been on 5mg for 4

years)

> and

> > I need to call in 2 weeks to update them on how he is or sooner

if

> > there are problems.

> >

> > I could kick myself for this one---in August at the pulmo appt.,

> the

> > dr. talked me out of food allergy testing (which I requested, so

I

> had

> > them off their allergy meds for the week--what a DRAG--we were

ALL

> > miserable that week!). But when we saw the GI later in the

month,

> I

> > said what happened, and he was surprised that the pulmo said

that

> > because 's tests were 4 years old. BUT, the GI did say

that

> he

> > can order the RAST tests if the need ever comes up. So, do we

now

> > need to do RAST testing with him to see if he is any more

allergic

> to

> > the foods and/or other things he was before and any new ones?

As

> a

> > baby he was lactose intolerant, but seemed to get over

that ....

> I

> > guess along with every answer comes even more questions.

> >

> > Thanks for putting up with me!

> >

> > Have a great day!

> > Meg

> >

>

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has eosinophill entropathy and I agree with everything that

said as we know each other from the eos group, but there are

lots of great doctors out there treating eos diease and maybe one

would be closer to you. I did not get where you lived.

Dr. Putnam in CCHMC

the team at CHOP

Boston childrens

Dr. Noel at milwaukee

and many others

Eosophill has been a huge issue for ALex as he is left on TPN from

it, but I will say that is not the norm. He has many ither issues at

this point. BUt with the right treatment you can get it under

control. The difference becomes how severe their PID is. It can

influence everything. That I have learned over the years. Hope this

helps.

> > >

> > > Well, we got the results of 's biopsies 2 days earlier

than

> I

> > had

> > > anticipated! He had high concentrations of eosinophils in his

> > > esophagus and colon. Hopefully this is the reason for his

pain.

> The

> > > dr. bumped him up to 10mg singulair (he's been on 5mg for 4

> years)

> > and

> > > I need to call in 2 weeks to update them on how he is or

sooner

> if

> > > there are problems.

> > >

> > > I could kick myself for this one---in August at the pulmo

appt.,

> > the

> > > dr. talked me out of food allergy testing (which I requested,

so

> I

> > had

> > > them off their allergy meds for the week--what a DRAG--we were

> ALL

> > > miserable that week!). But when we saw the GI later in the

> month,

> > I

> > > said what happened, and he was surprised that the pulmo said

> that

> > > because 's tests were 4 years old. BUT, the GI did say

> that

> > he

> > > can order the RAST tests if the need ever comes up. So, do we

> now

> > > need to do RAST testing with him to see if he is any more

> allergic

> > to

> > > the foods and/or other things he was before and any new ones?

> As

> > a

> > > baby he was lactose intolerant, but seemed to get over

> that ....

> > I

> > > guess along with every answer comes even more questions.

> > >

> > > Thanks for putting up with me!

> > >

> > > Have a great day!

> > > Meg

> > >

> >

>

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Hi Meg,

Thank for posting the info about your son's test. I think we're going to

put Conner through this too and probably Hayden, as well. I was curious to

know if they tested him for celiac? I'm really starting to wonder about this

for my boys.

Take care,

Mom to Conner (12, NEMO/XHIM, asthma,

Hashimoto's disease and resolved adrenal insufficiency),

Hayden (12, unknown immune deficiency, IBS and moderate hearing loss/aided),

Evan (12, unknown immune deficiency, asthma and mild hearing loss/unaided),

and Kelsey - (10, unknown immune deficiency and asthma)

Please visit us at www.caringbridge.org/in/connersmith

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