Re: Parvo and IgG replacement

[Guest guest]

I guess whenever you put anything into your body or ur

child's body it MAY have a virus with it. We were

told this both times when got blood

transfusion. Nothing is 100%. My mom's friend got

Hep. from a blood transfusion in the late 90's and so

did my husband's best friends mom. For us it was

choosing what was necessary for her to get better and

be healthy.

Candise Ott

mom to (LCHAD,low IGg level,speech

delayed,preemie, multiple infections and

viruses,physical therapy, delayed gastric emptying,

and severe acid reflux that has improved recently)

(carrier of LCHAD, speeched delayed but is

improving)

Kadian(carrier of LCHAD, normal 3 year old)

--- Dale Weatherford <dale@...> wrote:

> from Dale, Mom to Katy, grown and married

>

> I try to be a resource for you guys and want to make

> sure that what I

> share is helpful and correct. This is some

> information that I have

> gathered regarding the statement that Parvo (Fifth's

> Disease) can be

> transmitted through IgG replacement. I talked with

> a gentleman in the

> industry. He asked that I not use his name or

> product because in order

> to quote him directly, he would have to request a

> written statement from

> his legal department and that could take weeks to

> get approval. He

> felt, and I agreed, that this information was

> important to this group

> and wanted to get it out immediately. So, I am

> summarizing what we

> talked about.

>

> Here's why the statement that Parvo can be

> transmitted in IgG is very

> serious. Think about it. If a known virus can get

> through the process

> - then that opens the door for all unknown viruses

> to get through. And

> that's a scary proposition.

>

> Here's a list of all the previously unknown viruses

> that have been

> recently discovered: HIV, Hepatitis C, Hepatitus B,

> SARS, West Nile,

> Monkey Pox and Avian flu. All of those were totally

> unknown viruses

> until very recently. We have to know that our

> products are as viral

> safe as possible - in fact, we want them more than

> safe. But there are

> no 100% guarantees. That's why on every vial of

> IgG product --

> regardless of the brand. The legal department

> requires the following

> statement: No plasma product is 100% guaranteed

> safe.

>

> That said: Let's look at exactly what the process

> is that takes out

> viruses in IgG products.

>

> #1 Something called SD process: It instantly kills

> all lipid-enveloped

> viruses. Every product on the market has something

> that kills

> lipid-envelope viruses.

>

> But that's only the lipid-enveloped viruses such as

> HIV, Hepatitis, West

> Nile, SARS, etc. It does not include Parvo B19 -

> which is what causes

> Parvo or Fifths Disease. Parvo has no

> lipid-envelope.

>

> That virus and many others are not affected by the

> lipid envelope killers.

>

> #2 Baxter has created a 35 nanometer filtration

> system. It filters out

> anything greater than 35 nanometers.

>

> Now, Parvo B19 is only 18 nanometers across. That's

> a problem - right?

> No. The job of antibodies is to attach to germs.

> And that's what

> happens to our little germ in the batch. Antibodies

> attach to it

> readily -- it is a common germ and most everyone has

> antibodies against.

> In a pool of 2000 donors you are going to have

> plenty of antibodies to

> grab hold and that increases the size of the germ +

> antibodies to about

> 50 plus nanometers and therefore -- it won't pass

> the filter.

> By the way, HIV virus is approximately 100

> nanometers to start with --

> so no, it doesn't get through either.

>

>

> In addition to that, then Baxter has another

> checkpoint to absolutely

> make sure nothing survives: that's a low pH bath at

> 90 degrees

> temperature that kills both lipid-envelope and

> non-lipid envelope and it

> stays there for 3 weeks. Just in case something got

> by the other

> system. Which legally and theoretically could

> happen -- but proably

> wouldn't.

>

> So, Baxter has in place a triple purification

> system. But, in actuality

> -- all IgG replacement therapies have similar

> methods of purification.

>

> If you go to

>

>

http://www.plasmatherapeutics.org/en/qualitysafety_qseal.cfm

>

>

> you can read about the required industry

> purification guidelines.

>

>

>

> So... let's look at this statement that someone

> posted from a web-site.

>

>

> " While the processes used to de-activate viral and

> bacterial agents has

> drastically improved the safety of IVIG, it is not

> 100% fail

> safe..... "

>

> The first part of this statement is absolutely true.

> Until as recently

> as 5 years ago this system was not complete and it

> allowed some unknown

> viruses to slip through. Because of that the

> industry has responded

> with more rigorous techniques to purify the IgG.

> So... it is

> drastically improved recently. Yes.

>

> The second half of that statement is also

> technically and theoretically

> true. It is required by all legal departments just

> in case something

> should arise that they have no knowledge about --

> which DOES happen.

>

> " there are still reported cases despite processes

> used. "

>

> The man I talked with said that there is absolutely

> no reported cases of

> lipid-based viruses being transmitted and he's

> checking with his

> pathologist to see if there's any documented cases

> of Parvo being

> transmitted by IgG since these new procedures have

> been in place. He'll

> get back with me later.

>

> " While the chances of transmitting something are

> extremely low, they

> are, never-the- less, still there. "

>

> That is also legally and theoretically true.

>

> " The information is not limited to a single

> resource, if you query " IVIG

> adverse reactions+parvovirus " , many reports come up

> that state the fact

> that the products are not 100% safe....including

> safe from parvo. "

>

> This statement is somewhat interesting. Many

> people lump IgG with all

> other blood products. You have to be careful there.

> When you consider

> what viruses can be routinely transmitted with whole

> blood or even

> plasma -- you are talking about a whole 'nuther

> animal. Many blood

> products contain viruses, including Parvo. It is

> almost " expected " that

> you will transmit viruses with blood. But, IgG

> should not be lumped

> with those products. I have not taken the time to

> query all these

> reports. If someone finds one that is particularly

> troubling -- let me

> know. I'll be glad to look. But, I've found that

> general searches on

> the internet lead me to a lot of erroneous

> information. I want facts

> backed by facts.

>

>

> There is also one statement on the Quality of Blood

> Products web site

> that may confuse doctors and/or patients. It states

> that plasma

> donations are eliminated if they contain more than

> (I don't remember how

> many) parts of Parvo virus per liter of plasma. But

> -- you say -- that

>

=== message truncated ===

________________________________________________________________________________\

____

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[Guest guest]

This makes me curious.

My son has dysfunctional memory cells, so he gets the same things over

and over. Before he began Ig replacement 2 years ago at 3 years old, he

had about 5 separate diagnosed courses of 5th disease.

He has had a couple of courses of 5th disease since he began IG

replacement- now I wonder if he got those cases from the IG replacement?

- mom to in CT

________________________________

From: [mailto: ] On

Behalf Of Dale Weatherford

Sent: Tuesday, December 12, 2006 1:30 PM

Subject: Parvo and IgG replacement

from Dale, Mom to Katy, grown and married

I try to be a resource for you guys and want to make sure that

what I

share is helpful and correct. This is some information that I

have

gathered regarding the statement that Parvo (Fifth's Disease)

can be

transmitted through IgG replacement. I talked with a gentleman

in the

industry. He asked that I not use his name or product because in

order

to quote him directly, he would have to request a written

statement from

his legal department and that could take weeks to get approval.

He

felt, and I agreed, that this information was important to this

group

and wanted to get it out immediately. So, I am summarizing what

we

talked about.

Here's why the statement that Parvo can be transmitted in IgG is

very

serious. Think about it. If a known virus can get through the

process

- then that opens the door for all unknown viruses to get

through. And

that's a scary proposition.

Here's a list of all the previously unknown viruses that have

been

recently discovered: HIV, Hepatitis C, Hepatitus B, SARS, West

Nile,

Monkey Pox and Avian flu. All of those were totally unknown

viruses

until very recently. We have to know that our products are as

viral

safe as possible - in fact, we want them more than safe. But

there are

no 100% guarantees. That's why on every vial of IgG product --

regardless of the brand. The legal department requires the

following

statement: No plasma product is 100% guaranteed safe.

That said: Let's look at exactly what the process is that takes

out

viruses in IgG products.

#1 Something called SD process: It instantly kills all

lipid-enveloped

viruses. Every product on the market has something that kills

lipid-envelope viruses.

But that's only the lipid-enveloped viruses such as HIV,

Hepatitis, West

Nile, SARS, etc. It does not include Parvo B19 - which is what

causes

Parvo or Fifths Disease. Parvo has no lipid-envelope.

That virus and many others are not affected by the lipid

envelope killers.

#2 Baxter has created a 35 nanometer filtration system. It

filters out

anything greater than 35 nanometers.

Now, Parvo B19 is only 18 nanometers across. That's a problem -

right?

No. The job of antibodies is to attach to germs. And that's what

happens to our little germ in the batch. Antibodies attach to it

readily -- it is a common germ and most everyone has antibodies

against.

In a pool of 2000 donors you are going to have plenty of

antibodies to

grab hold and that increases the size of the germ + antibodies

to about

50 plus nanometers and therefore -- it won't pass the filter.

By the way, HIV virus is approximately 100 nanometers to start

with --

so no, it doesn't get through either.

In addition to that, then Baxter has another checkpoint to

absolutely

make sure nothing survives: that's a low pH bath at 90 degrees

temperature that kills both lipid-envelope and non-lipid

envelope and it

stays there for 3 weeks. Just in case something got by the other

system. Which legally and theoretically could happen -- but

proably

wouldn't.

So, Baxter has in place a triple purification system. But, in

actuality

-- all IgG replacement therapies have similar methods of

purification.

If you go to

http://www.plasmatherapeutics.org/en/qualitysafety_qseal.cfm

<http://www.plasmatherapeutics.org/en/qualitysafety_qseal.cfm>

you can read about the required industry purification

guidelines.

So... let's look at this statement that someone posted from a

web-site.

" While the processes used to de-activate viral and bacterial

agents has

drastically improved the safety of IVIG, it is not 100% fail

safe..... "

The first part of this statement is absolutely true. Until as

recently

as 5 years ago this system was not complete and it allowed some

unknown

viruses to slip through. Because of that the industry has

responded

with more rigorous techniques to purify the IgG. So... it is

drastically improved recently. Yes.

The second half of that statement is also technically and

theoretically

true. It is required by all legal departments just in case

something

should arise that they have no knowledge about -- which DOES

happen.

" there are still reported cases despite processes used. "

The man I talked with said that there is absolutely no reported

cases of

lipid-based viruses being transmitted and he's checking with his

pathologist to see if there's any documented cases of Parvo

being

transmitted by IgG since these new procedures have been in

place. He'll

get back with me later.

" While the chances of transmitting something are extremely low,

they

are, never-the- less, still there. "

That is also legally and theoretically true.

" The information is not limited to a single resource, if you

query " IVIG

adverse reactions+parvovirus " , many reports come up that state

the fact

that the products are not 100% safe....including safe from

parvo. "

This statement is somewhat interesting. Many people lump IgG

with all

other blood products. You have to be careful there. When you

consider

what viruses can be routinely transmitted with whole blood or

even

plasma -- you are talking about a whole 'nuther animal. Many

blood

products contain viruses, including Parvo. It is almost

" expected " that

you will transmit viruses with blood. But, IgG should not be

lumped

with those products. I have not taken the time to query all

these

reports. If someone finds one that is particularly troubling --

let me

know. I'll be glad to look. But, I've found that general

searches on

the internet lead me to a lot of erroneous information. I want

facts

backed by facts.

There is also one statement on the Quality of Blood Products web

site

that may confuse doctors and/or patients. It states that plasma

donations are eliminated if they contain more than (I don't

remember how

many) parts of Parvo virus per liter of plasma. But -- you say

-- that

means there is Parvo virus in there! No. It means that they

throw

away the initial donation if it has too much Parvo in it. Then

it goes

through the process and while -- legally -- they can't claim to

have it

100% gone -- they do claim to have reduced the amount by 10 to

the 17

zeros place. So if you started out with a million parts -- you

still

would have zero at the end. But not absolutely zero - legally

and

theoretically!

So..... that's your chemistry lesson for today. I hope that it

helps to

reassure somebody out there that IgG is not something that

transmits

viruses and other crud. It's just not possible with today's

system of

purification.

Have people been contaminated in the past -- oh yes!!!!! Could

they

become contaminated in the future? Legally and theoretically,

yes.

Probability wise -- probably not.

Hope that helps.

I'll post again whenever I hear from the pathologist at a major

IgG

facility.

In His service,

dale

[Guest guest]

Candise Ott wrote:

>

>

> I guess whenever you put anything into your body or ur

> child's body it MAY have a virus with it. We were

> told this both times when got blood

> transfusion. Nothing is 100%. My mom's friend got

> Hep. from a blood transfusion in the late 90's and so

> did my husband's best friends mom. For us it was

> choosing what was necessary for her to get better and

> be healthy.

Exactly. But a blood transfusion is DIFFERENT from IgG replacement!

In His servive,

dale

[Guest guest]

" IgG is not something that transmits viruses and other crud. It's

just not possible with today's system of purification. "

One final note! Yeehawwww! No need to continue with my ledgers and

diaries full of labels, lot numbers, dosages diligently kept in the

unlikely.....now apparently impossible event that we encounter any

problems as a result of a contaminated batch of Ig product etc!

We're safe! Right? I spent far too much time worrying about the

possiblities. Oh if I could turn back the clock and not have waited

so long to weigh the pros and cons....perhaps avoiding a few

unneccesary illnesses.

" Never say never " ....there are far to many people who were told that

they were 100% safe that would argue otherwise. It is not to say

that there is anything to worry about....but the fact that the FDA,

the NIH, and the manufacturers of Ig Replacement products are not

willing to say that their products are 100% safe.....drives me to

continue to know and understand that the risk and possibility exists

and I will always keep an open mind....knowing that I have made the

best decision for my children. That chance of 1 in a million...that

it could happen....that there is no absolute gaurantee that products

are, without question, safe. I don't believe it is a matter legal

logistics; I believe it is a matter of logistic uncertaintly that any

Ig Product is 100% safe....to become complacent to the safety

related to anything being introduced into my body or the bodies of my

babies that God did not put there.....food, drug or otherwise, and

thereby letting down our guard, would be irresponsible on my part. We

were clearly warned of the " possiblity " that we could be exposed to

something through Ig replacement therapy.....by our hematologist; by

our immunologist; by our pediatricians. We made a decision to begin

therapy because we knew that the likelyhood that we would be exposed

to something was extremely low....especially when compared to the

chance that we would loose our precious daughters to pnuemonia.

Finally, it is so important for us all to keep an open mind.....to

know all sides......to make informed decisions.....and to exercise

caution to the " safest " degree.........to be prepared for the unknown

or small possiblities, but not frozen in fear of them......and to

keep concise records in the event that, God forbid, something

happens....that in 10 years, they find out that there was something

they did not know.

I received Ig replacement during a time that it was not safe (from

1962 to 1972).....that it likely carried horrible things and they

were passed on to me. And I received a lot of it. Thankfully,

practices have changed......knowledge that there were things passed

on to patients....and not denying it.....has resulted in

manufacturer's finding and improving ways to make products safe. But

I have no way to go back and determine if I was one of those that

could have been infected.....because my parents were told it was

safe.....100% safe and there was nothing to worry about. There was

no record keeping.....by anyone. I have no access to anything

related to the Ig replacement administered to me during those years.

I have no way of knowing if my arthritis is because of my Ig

replacement or if it is because of my immune disorder. I don't know

what to expect. They said it was safe then too....that there was no

chance anything was passed to patients. Now, some 35 years or more

later, I now know differently.

Never say never.....never assume.....never let your guard

down.....because there is that one chance in a million.....and that

is all it takes for me to keep a watchful eye.

Terri

>

> from Dale, Mom to Katy, grown and married

>

> I try to be a resource for you guys and want to make sure that what

I

> share is helpful and correct. This is some information that I have

> gathered regarding the statement that Parvo (Fifth's Disease) can

be

> transmitted through IgG replacement. I talked with a gentleman in

the

> industry. He asked that I not use his name or product because in

order

> to quote him directly, he would have to request a written statement

from

> his legal department and that could take weeks to get approval. He

> felt, and I agreed, that this information was important to this

group

> and wanted to get it out immediately. So, I am summarizing what we

> talked about.

>

> Here's why the statement that Parvo can be transmitted in IgG is

very

> serious. Think about it. If a known virus can get through the

process

> - then that opens the door for all unknown viruses to get through.

And

> that's a scary proposition.

>

> Here's a list of all the previously unknown viruses that have been

> recently discovered: HIV, Hepatitis C, Hepatitus B, SARS, West

Nile,

> Monkey Pox and Avian flu. All of those were totally unknown

viruses

> until very recently. We have to know that our products are as

viral

> safe as possible - in fact, we want them more than safe. But there

are

> no 100% guarantees. That's why on every vial of IgG product --

> regardless of the brand. The legal department requires the

following

> statement: No plasma product is 100% guaranteed safe.

>

> That said: Let's look at exactly what the process is that takes

out

> viruses in IgG products.

>

> #1 Something called SD process: It instantly kills all lipid-

enveloped

> viruses. Every product on the market has something that kills

> lipid-envelope viruses.

>

> But that's only the lipid-enveloped viruses such as HIV, Hepatitis,

West

> Nile, SARS, etc. It does not include Parvo B19 - which is what

causes

> Parvo or Fifths Disease. Parvo has no lipid-envelope.

>

> That virus and many others are not affected by the lipid envelope

killers.

>

> #2 Baxter has created a 35 nanometer filtration system. It

filters out

> anything greater than 35 nanometers.

>

> Now, Parvo B19 is only 18 nanometers across. That's a problem -

right?

> No. The job of antibodies is to attach to germs. And that's what

> happens to our little germ in the batch. Antibodies attach to it

> readily -- it is a common germ and most everyone has antibodies

against.

> In a pool of 2000 donors you are going to have plenty of

antibodies to

> grab hold and that increases the size of the germ + antibodies to

about

> 50 plus nanometers and therefore -- it won't pass the filter.

> By the way, HIV virus is approximately 100 nanometers to start

with --

> so no, it doesn't get through either.

>

>

> In addition to that, then Baxter has another checkpoint to

absolutely

> make sure nothing survives: that's a low pH bath at 90 degrees

> temperature that kills both lipid-envelope and non-lipid envelope

and it

> stays there for 3 weeks. Just in case something got by the other

> system. Which legally and theoretically could happen -- but

proably

> wouldn't.

>

> So, Baxter has in place a triple purification system. But, in

actuality

> -- all IgG replacement therapies have similar methods of

purification.

>

> If you go to

>

> http://www.plasmatherapeutics.org/en/qualitysafety_qseal.cfm

>

>

> you can read about the required industry purification guidelines.

>

>

>

> So... let's look at this statement that someone posted from a web-

site.

>

>

> " While the processes used to de-activate viral and bacterial agents

has

> drastically improved the safety of IVIG, it is not 100% fail

> safe..... "

>

> The first part of this statement is absolutely true. Until as

recently

> as 5 years ago this system was not complete and it allowed some

unknown

> viruses to slip through. Because of that the industry has

responded

> with more rigorous techniques to purify the IgG. So... it is

> drastically improved recently. Yes.

>

> The second half of that statement is also technically and

theoretically

> true. It is required by all legal departments just in case

something

> should arise that they have no knowledge about -- which DOES happen.

>

> " there are still reported cases despite processes used. "

>

> The man I talked with said that there is absolutely no reported

cases of

> lipid-based viruses being transmitted and he's checking with his

> pathologist to see if there's any documented cases of Parvo being

> transmitted by IgG since these new procedures have been in place.

He'll

> get back with me later.

>

> " While the chances of transmitting something are extremely low,

they

> are, never-the- less, still there. "

>

> That is also legally and theoretically true.

>

> " The information is not limited to a single resource, if you

query " IVIG

> adverse reactions+parvovirus " , many reports come up that state the

fact

> that the products are not 100% safe....including safe from parvo. "

>

> This statement is somewhat interesting. Many people lump IgG with

all

> other blood products. You have to be careful there. When you

consider

> what viruses can be routinely transmitted with whole blood or even

> plasma -- you are talking about a whole 'nuther animal. Many blood

> products contain viruses, including Parvo. It is almost " expected "

that

> you will transmit viruses with blood. But, IgG should not be

lumped

> with those products. I have not taken the time to query all these

> reports. If someone finds one that is particularly troubling --

let me

> know. I'll be glad to look. But, I've found that general searches

on

> the internet lead me to a lot of erroneous information. I want

facts

> backed by facts.

>

>

> There is also one statement on the Quality of Blood Products web

site

> that may confuse doctors and/or patients. It states that plasma

> donations are eliminated if they contain more than (I don't

remember how

> many) parts of Parvo virus per liter of plasma. But -- you say --

that

> means there is Parvo virus in there! No. It means that they

throw

> away the initial donation if it has too much Parvo in it. Then it

goes

> through the process and while -- legally -- they can't claim to

have it

> 100% gone -- they do claim to have reduced the amount by 10 to the

17

> zeros place. So if you started out with a million parts -- you

still

> would have zero at the end. But not absolutely zero - legally and

> theoretically!

>

>

> So..... that's your chemistry lesson for today. I hope that it

helps to

> reassure somebody out there that IgG is not something that

transmits

> viruses and other crud. It's just not possible with today's system

of

> purification.

>

> Have people been contaminated in the past -- oh yes!!!!! Could

they

> become contaminated in the future? Legally and theoretically, yes.

> Probability wise -- probably not.

>

> Hope that helps.

>

> I'll post again whenever I hear from the pathologist at a major IgG

> facility.

>

> In His service,

> dale

>

[Guest guest]

cerdaclan wrote:

>

>

> " Never say never " ....there are far to many people who were told that

> they were 100% safe that would argue otherwise.

from Dale,

Terri, I agree with your statements in this e-mail. No one can

absolutely guarantee the safety of IgG replacement and we should always

make educated, informed decisions. That's the reason for my previous

e-mail -- to make sure that everyone knows the facts about the

purification process of IgG at this point in time. That's different

from stating that Parvo gets passed through IgG. I'm still waiting for

the final word on that from a pathologist who can adequately answer that

question.

In His service,

dale

[Guest guest]

Ladden wrote:

>

>

> This makes me curious.

>

> My son has dysfunctional memory cells, so he gets the same things over

> and over. Before he began Ig replacement 2 years ago at 3 years old, he

> had about 5 separate diagnosed courses of 5th disease.

>

> He has had a couple of courses of 5th disease since he began IG

> replacement- now I wonder if he got those cases from the IG replacement?

>

> - mom to in CT

>

from dale,

-- that's what I just wrote about in this e-mail that you

responded to. Was it not clear? Parvo cannot survive the purification

system that is implemented today for IgG replacement. As far as I know

there have been no documented cases. You yourself said that he got

Parvo before IVIG and now he's still getting Parvo. Why blame IVIG?

Parvo is very contangious -- it's passed around very easily -- he could

have gotten it anywhere -- but the possibility that he got it from IgG

replacement is just not realistic.

I hope I haven't confused everyone!

In His service,

dale

[Guest guest]

I was a bit confused--you were right.

________________________________

From: [mailto: ] On

Behalf Of Dale Weatherford

Sent: Tuesday, December 12, 2006 8:24 PM

Subject: Re: Parvo and IgG replacement

Ladden wrote:

>

>

> This makes me curious.

>

> My son has dysfunctional memory cells, so he gets the same

things over

> and over. Before he began Ig replacement 2 years ago at 3

years old, he

> had about 5 separate diagnosed courses of 5th disease.

>

> He has had a couple of courses of 5th disease since he began

IG

> replacement- now I wonder if he got those cases from the IG

replacement?

>

> - mom to in CT

>

from dale,

-- that's what I just wrote about in this e-mail that you

responded to. Was it not clear? Parvo cannot survive the

purification

system that is implemented today for IgG replacement. As far as

I know

there have been no documented cases. You yourself said that he

got

Parvo before IVIG and now he's still getting Parvo. Why blame

IVIG?

Parvo is very contangious -- it's passed around very easily --

he could

have gotten it anywhere -- but the possibility that he got it

from IgG

replacement is just not realistic.

I hope I haven't confused everyone!

In His service,

dale

[Guest guest]

Severe recurrent parvo is often treated with.. You got it - IVIG - it's an

off label use, but heck - most of the uses of IVIG is off label.

Dayna

_____

From: [mailto: ] On Behalf Of

Ladden

Sent: Wednesday, December 13, 2006 7:38 AM

Subject: RE: Parvo and IgG replacement

I was a bit confused--you were right.

________________________________

From: groups (DOT) <mailto:%40> com

[mailto:groups (DOT) <mailto:%40> com] On

Behalf Of Dale Weatherford

Sent: Tuesday, December 12, 2006 8:24 PM

groups (DOT) <mailto:%40> com

Subject: Re: Parvo and IgG replacement

Ladden wrote:

>

>

> This makes me curious.

>

> My son has dysfunctional memory cells, so he gets the same

things over

> and over. Before he began Ig replacement 2 years ago at 3

years old, he

> had about 5 separate diagnosed courses of 5th disease.

>

> He has had a couple of courses of 5th disease since he began

IG

> replacement- now I wonder if he got those cases from the IG

replacement?

>

> - mom to in CT

>

from dale,

-- that's what I just wrote about in this e-mail that you

responded to. Was it not clear? Parvo cannot survive the

purification

system that is implemented today for IgG replacement. As far as

I know

there have been no documented cases. You yourself said that he

got

Parvo before IVIG and now he's still getting Parvo. Why blame

IVIG?

Parvo is very contangious -- it's passed around very easily --

he could

have gotten it anywhere -- but the possibility that he got it

from IgG

replacement is just not realistic.

I hope I haven't confused everyone!

In His service,

dale

[Guest guest]

I know that a blood transfusion is different but they

were told that it was safe...that it was

filtered...that there was no way they could receive

any of kind of illness but yet both have

suffered...almost died from the heptitsis. For us she

could die without it and also from being sick with a

FOD so we have to hope that nothing will happen.

People make mistakes...machines fail...so to say not

to worry isn't realistic. They would make that

statement if there was no cause for concern.

Candise Ott

--- Dale Weatherford <dale@...> wrote:

> Candise Ott wrote:

> >

> >

> > I guess whenever you put anything into your body

> or ur

> > child's body it MAY have a virus with it. We were

> > told this both times when got blood

> > transfusion. Nothing is 100%. My mom's friend got

> > Hep. from a blood transfusion in the late 90's and

> so

> > did my husband's best friends mom. For us it was

> > choosing what was necessary for her to get better

> and

> > be healthy.

>

>

> Exactly. But a blood transfusion is DIFFERENT from

> IgG replacement!

>

> In His servive,

> dale

>

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