Visceral fat in HIV-infected men with clinical evidence of lipodystrophy was similar to HIV-uninfected men.

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I guess MACS agrees with the FRAM study in saying that we do not have more belly fat than HIV negatives.....ummmmfull text :http://www.aidsrestherapy.com/content/pdf/1742-6405-6-8.pdf Visceral fat in HIV-infected men with clinical evidence of lipodystrophy was similar to HIV-uninfected men.  AIDS Res Ther. 2009 May 13;6(1):8. [Epub ahead of print]Fat distribution and longitudinal anthropometric changes in HIV-infected men with and without clinical evidence of lipodystrophy and HIV-uninfected controls: A substudy of the Multicenter AIDS Cohort Study.Brown TT, Xu X,  M, Singh J, Kingsley LA, Palella FJ Jr, Witt MD, Margolick JB, Dobs AS.ABSTRACT: BACKGROUND: Fat abnormalities are common among HIV-infected persons, but few studies have compared regional body fat distribution, including visceral fat, in HIV-infected and HIV-uninfected persons. METHODS: Between 1999 and 2002, 39 men with clinical

evidence of fat abnormalities (LIPO+), 23 HIV-infected men without clinical evidence of body composition changes (LIPO -), and 32 HIV-uninfected men were recruited from the four sites of the Multicenter AIDS Cohort Study (MACS). Participants underwent dual x-ray absorptiometry, quantitative computerized tomography of the abdomen and thigh, and circumference measurements of the waist, hip and thigh. Circumference measurements at each semi-annual MACS visit between 1999 and 2004 were used to compare average anthropometric changes in the 3 groups. RESULTS: Body mass index (BMI) and total lean mass were lower in LIPO+ men compared to the LIPO- men and the HIV- uninfected controls (BMI: 23.6 +/- 0.7 vs 26.9 +/- 1.0 vs 28.9+/- 0.8 kg/m2, respectively, p< 0.0001). The average amount of visceral adipose tissue (VAT) in the LIPO+ men was greater than in the LIPO- men, but similar to the HIV- uninfected men (133 +/- 10 vs 110 +/- 14 vs 156 +/- 12 cm2,

respectively, overall p< 0.03), even after adjustment for BMI or lean mass. Subcutaneous adipose tissue (thigh, abdomen) and total extremity fat were less in the HIV-infected men (LIPO+ and LIPO-) than in the HIV-uninfected men. Over an average of 4 years of follow-up, waist circumferences increased at a similar rate in each of the groups, hip and thigh circumferences remained stable. CONCLUSIONS: Even among those without clinical evidence of fat abnormalities, subcutaneous lipoatrophy was observed in HIV-infected patients, compared to HIV-uninfected controls. Visceral fat in HIV-infected men with clinical evidence of lipodystrophy was similar to HIV-uninfected men.Regards, Vergelpowerusa dot org