Re: Side Effects later in treatment -Vertex

[Guest guest]

Apparently Wall Street has taken notice of the trials for Vertex (Liz

and tell us more)and the fast tracking of it by the FDA, because there

was a short story on one of the stock market channels that's always on

the tv in our lobby at work. I stopped dead in my tracks when I saw

it. Dollar signs means speed to the market! Maybe in a year or so we

won't be talking about Pegysas vs. Peg-Intron?!

Makes me wonder if I should wait? But this fatigue is getting to me;

figure if I feel like crap, might as well REALLY feel like crap?!

> >

>

> My knowledge is limited, but I believe there are two different drug

> > companies

> > and also some doctors prefer one treatment over the other-

> > Pegysis vs Peg-Intron depending on Genotype type and all..

> > Ally, you'd be surprised what all you can learn by using Google..

> >

> > Sheena

> >

>

>

> Well, I did a little looking and apparently the studies they have

done so

> far have been biased toward Peg-Intron but there is a big study

happening

> right now that will be finished in 2007 to see which one is more

effective:

> http://www.hivandhepatitis.com/hep_c/news/2005/012405_a.html

>

> The *biased* studies showed that Peg-Intron was more. The big difference

> between the two is:

>

>

> > that Pegasys is a more bulky branched molecule than

> > Peg-Intron; Pegasys has a molecular mass of 40 kilodaltons (kDa),

compared

> >

> > with 12 kDa for Peg-Intron. In general, they noted, Peg-Intron has a

> > larger volume

> > of distribution and higher renal clearance than Pegasys. Typically,

> > Peg-Intron is

> > dosed based on body weight, while Pegasys is administered as a

flat dose.

>

>

> Thanks for the tip of googling it. I should have thought of that but

wasn't

> thiking because of being too tired, lol, ah well, such as life. That's

> what's great about this group. A bunch of minds are far better then one

> alone!

>

> Ally

>

[Guest guest]

Sorry to hear you feel so bad today Geri! I hope it passes quickly!

>

>

>

> In a message dated 10/29/2006 9:36:06 AM Central Standard Time,

> marvindamartian05@... writes:

>

> Makes me wonder if I should wait? But this fatigue is getting to me;

> figure if I feel like crap, might as well REALLY feel like crap?!

>

>

>

>

> LOL yeah thats the spirit...but then again maybe you dont know

what really

> feeling like crap feels like...I am to the point I am getting out of

breath

> again...but I am mostly always hot...dont have the chills..as of

yet..geri

>

[Guest guest]

In a message dated 10/29/2006 4:52:06 PM Central Standard Time, marvindamartian05@... writes:

Sorry to hear you feel so bad today Geri! I hope it passes quickly!

I woke up feeling terrible still.. I am puffy, and my heart rate elevates to over 100 just walking from one room to the next. I have only a slight headache today, but I want to bite everyone eles off...and I have no one to take care of some things for me around here..it is hard..geri

[Guest guest]

Know the frustration of being on treatment, feeling like yesterday's leftovers, and not having someone to do those important things that need to get done. You are on anti-depressants right? Take it easy today, tell everybody Doc said so. LOL Housework can wait till you feel better believe it or not. Or call some of those friends that promised to help during this. (did they?) I took some up on their offers to help. It was hard because I really didn't want to ask. But I did. Sorry hon you are feeling so bad. Love Janet us4heavenbound@... wrote: In a message dated 10/29/2006 4:52:06 PM Central Standard Time, marvindamartian05 writes: Sorry to hear you feel so bad today Geri! I hope it passes quickly! I woke up feeling terrible still.. I am puffy, and my heart rate elevates to over 100 just walking from one room to the next. I have only a slight headache today, but I want to bite everyone eles off...and I have no one to take care of some

things for me around here..it is hard..geri Take the ordinary things of life, and make them your own. Do the impossible with a smile

[Guest guest]

Know the frustration of being on treatment, feeling like yesterday's leftovers, and not having someone to do those important things that need to get done. You are on anti-depressants right? Take it easy today, tell everybody Doc said so. LOL Housework can wait till you feel better believe it or not. Or call some of those friends that promised to help during this. (did they?) I took some up on their offers to help. It was hard because I really didn't want to ask. But I did. Sorry hon you are feeling so bad. Love Janet us4heavenbound@... wrote: In a message dated 10/29/2006 4:52:06 PM Central Standard Time, marvindamartian05 writes: Sorry to hear you feel so bad today Geri! I hope it passes quickly! I woke up feeling terrible still.. I am puffy, and my heart rate elevates to over 100 just walking from one room to the next. I have only a slight headache today, but I want to bite everyone eles off...and I have no one to take care of some

things for me around here..it is hard..geri Take the ordinary things of life, and make them your own. Do the impossible with a smile

[Guest guest]

The vertex drug is used along with an interferon type drug .

Re: Side Effects later in treatment -Vertex

Apparently Wall Street has taken notice of the trials for Vertex (Lizand tell us more)and the fast tracking of it by the FDA, because therewas a short story on one of the stock market channels that's always onthe tv in our lobby at work. I stopped dead in my tracks when I sawit. Dollar signs means speed to the market! Maybe in a year or so wewon't be talking about Pegysas vs. Peg-Intron?!Makes me wonder if I should wait? But this fatigue is getting to me;figure if I feel like crap, might as well REALLY feel like crap?!> >> > My knowledge is limited, but I believe there are two different drug> > companies> > and also some doctors prefer one treatment over the other-> > Pegysis vs Peg-Intron depending on Genotype type and all..> > Ally, you'd be surprised what all you can learn by using Google..> >> > Sheena> >> > > Well, I did a little looking and apparently the studies they havedone so> far have been biased toward Peg-Intron but there is a big studyhappening> right now that will be finished in 2007 to see which one is moreeffective:> http://www.hivandhepatitis.com/hep_c/news/2005/012405_a.html> > The *biased* studies showed that Peg-Intron was more. The big difference> between the two is:> > > > that Pegasys is a more bulky branched molecule than> > Peg-Intron; Pegasys has a molecular mass of 40 kilodaltons (kDa),compared> >> > with 12 kDa for Peg-Intron. In general, they noted, Peg-Intron has a> > larger volume> > of distribution and higher renal clearance than Pegasys. Typically,> > Peg-Intron is> > dosed based on body weight, while Pegasys is administered as aflat dose.> > > Thanks for the tip of googling it. I should have thought of that butwasn't> thiking because of being too tired, lol, ah well, such as life. That's> what's great about this group. A bunch of minds are far better then one> alone!> > Ally>

[Guest guest]

Oh, well, guess we WILL be talking about Peg-this and Preg-that for

awhile!

> > >

> >

> > My knowledge is limited, but I believe there are two different

drug

> > > companies

> > > and also some doctors prefer one treatment over the other-

> > > Pegysis vs Peg-Intron depending on Genotype type and all..

> > > Ally, you'd be surprised what all you can learn by using

Google..

> > >

> > > Sheena

> > >

> >

> >

> > Well, I did a little looking and apparently the studies they

have

> done so

> > far have been biased toward Peg-Intron but there is a big study

> happening

> > right now that will be finished in 2007 to see which one is more

> effective:

> > http://www.hivandhepatitis.com/hep_c/news/2005/012405_a.html

> >

> > The *biased* studies showed that Peg-Intron was more. The big

difference

> > between the two is:

> >

> >

> > > that Pegasys is a more bulky branched molecule than

> > > Peg-Intron; Pegasys has a molecular mass of 40 kilodaltons

(kDa),

> compared

> > >

> > > with 12 kDa for Peg-Intron. In general, they noted, Peg-

Intron has a

> > > larger volume

> > > of distribution and higher renal clearance than Pegasys.

Typically,

> > > Peg-Intron is

> > > dosed based on body weight, while Pegasys is administered as a

> flat dose.

> >

> >

> > Thanks for the tip of googling it. I should have thought of

that but

> wasn't

> > thiking because of being too tired, lol, ah well, such as life.

That's

> > what's great about this group. A bunch of minds are far better

then one

> > alone!

> >

> > Ally

> >

>

[Guest guest]

Oops, meant to say " Peg-that " ...not " preg " ...my mind's not right

today...

> > > >

> > >

> > > My knowledge is limited, but I believe there are two

different

> drug

> > > > companies

> > > > and also some doctors prefer one treatment over the other-

> > > > Pegysis vs Peg-Intron depending on Genotype type and all..

> > > > Ally, you'd be surprised what all you can learn by using

> Google..

> > > >

> > > > Sheena

> > > >

> > >

> > >

> > > Well, I did a little looking and apparently the studies they

> have

> > done so

> > > far have been biased toward Peg-Intron but there is a big

study

> > happening

> > > right now that will be finished in 2007 to see which one is

more

> > effective:

> > > http://www.hivandhepatitis.com/hep_c/news/2005/012405_a.html

> > >

> > > The *biased* studies showed that Peg-Intron was more. The big

> difference

> > > between the two is:

> > >

> > >

> > > > that Pegasys is a more bulky branched molecule than

> > > > Peg-Intron; Pegasys has a molecular mass of 40 kilodaltons

> (kDa),

> > compared

> > > >

> > > > with 12 kDa for Peg-Intron. In general, they noted, Peg-

> Intron has a

> > > > larger volume

> > > > of distribution and higher renal clearance than Pegasys.

> Typically,

> > > > Peg-Intron is

> > > > dosed based on body weight, while Pegasys is administered

as a

> > flat dose.

> > >

> > >

> > > Thanks for the tip of googling it. I should have thought of

> that but

> > wasn't

> > > thiking because of being too tired, lol, ah well, such as

life.

> That's

> > > what's great about this group. A bunch of minds are far

better

> then one

> > > alone!

> > >

> > > Ally

> > >

> >

>

[Guest guest]

LOL yup it looks that way , but at least the riba can be taken out of the picture soon .

Re: Side Effects later in treatment -Vertex

Oh, well, guess we WILL be talking about Peg-this and Preg-that for awhile!> > >> > > > My knowledge is limited, but I believe there are two different drug> > > companies> > > and also some doctors prefer one treatment over the other-> > > Pegysis vs Peg-Intron depending on Genotype type and all..> > > Ally, you'd be surprised what all you can learn by using Google..> > >> > > Sheena> > >> > > > > > Well, I did a little looking and apparently the studies they have> done so> > far have been biased toward Peg-Intron but there is a big study> happening> > right now that will be finished in 2007 to see which one is more> effective:> > http://www.hivandhepatitis.com/hep_c/news/2005/012405_a.html> > > > The *biased* studies showed that Peg-Intron was more. The big difference> > between the two is:> > > > > > > that Pegasys is a more bulky branched molecule than> > > Peg-Intron; Pegasys has a molecular mass of 40 kilodaltons (kDa),> compared> > >> > > with 12 kDa for Peg-Intron. In general, they noted, Peg-Intron has a> > > larger volume> > > of distribution and higher renal clearance than Pegasys. Typically,> > > Peg-Intron is> > > dosed based on body weight, while Pegasys is administered as a> flat dose.> > > > > > Thanks for the tip of googling it. I should have thought of that but> wasn't> > thiking because of being too tired, lol, ah well, such as life. That's> > what's great about this group. A bunch of minds are far better then one> > alone!> > > > Ally> >>