Guest guest Posted December 14, 2005 Report Share Posted December 14, 2005 I just thought I post a quick note. I have a son 4 years with cvid among other issues. We now see Dr. Geha who has decided to test me given my past illnesses. Some of my labs came back and I was hoping someone may be able to give insight IGG 758 which is good, IGA 69 normal is 70-312 they like to see it in the middle,IGM 22 normal 42-240 and a response to vaccines ? 9 of 14 I don't understand what that means had 3 of 8 and has low IGG, IGA, IGM and 4 sub classes too. any wisdom? Dawn mother to --------------------------------- Find Great Deals on Holiday Gifts at Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 14, 2005 Report Share Posted December 14, 2005 Dale, just saw your post to Dawn, re: CVID...does this run true for kids, when their IGG is below normal and one subclass is low, with poor response to vaccine??? We don't have a firm diagnosis yet for , but due to the declining iGG level, poor response to vaccine and infection rate/mouth sores, we are going to start subq IG...in the next couple of weeks. Just wondering...Sure appreciate your experience. Quoting Dale Weatherford <dale@...>: > > > > > Some of my labs came back and I was hoping someone may be able to give > > insight > > > > IGG 758 which is good, IGA 69 normal is 70-312 they like to see it in > > the middle, > > > > IGM 22 normal 42-240 > > > > > > from Dale, > > > > Dawn, did they check the subclasses for IgG? I think that could be > > critical in your case. > > > > Here's my thoughts: IgM is created first and then differentiates into > > IgA or IgG whichever is needed most. My suspicion is that there's > > something missing in the IgG subclasses that is " using up " all the IgM, > > causing the IgA to be low and causing a lack of protection to some > > vaccines. But that's just suspicion on my part. > > > > I hope that they checked the subclasses and that they will be back soon. > > If indeed one of them is low -- I suspect you've got yourself the > > diagnosis of CVID. If the subclasses are fine -- then you are probably > > going to be considered a borderline case that has not " fully developed " > > yet and they may play " let's wait and see what happens " . Which is not > > fun. Even so, prophylactic antibiotics might be helpful since you are > > missing some responses to vaccinations. > > > > That's another thing that will be important to know is which vaccines > > you did not respond to. Some things you probably would never encounter > > -- but others will be considered essential and a " must " to start IVIG. > > > > Whatever the diagnosis -- hopefully they can stop the recurring > > infections and get you feeling better -- that's the focus! Hang in > > there. I'm praying for your peace as you deal with all this waiting and > > not-knowing. May God bless you today. > > > > In His service, > > dale > > > > > > > > > > > > > This forum is open to parents and caregivers of children diagnosed with a > Primary Immune Deficiency. Opinions or medical advice stated here are the > sole responsibility of the poster and should not be taken as professional > advice. > > > > To unsubscribe -unsubscribegroups (DOT) > > To search group archives go to: > /messages > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 14, 2005 Report Share Posted December 14, 2005 lmschatz@... wrote: > Dale, just saw your post to Dawn, re: CVID...does this run true for kids, > when their IGG is below normal and one subclass is low, with poor response to > vaccine??? We don't have a firm diagnosis yet for , but due to the > declining iGG level, poor response to vaccine and infection rate/mouth sores, > we are going to start subq IG...in the next couple of weeks. > > > Just wondering...Sure appreciate your experience. > > from Dale, , I'm not sure of your question? I beleieve the definition of CVID that is most often used is low IgG with at least one other Ig being low -- either A or M. But I may be wrong. I'm feeling a little rusty these days. If you are asking if the IgM is a precursor to IgA and IgG in kids -- then yes -- it's the same set-up. Now be aware that CVID or Common Variable is the exact same thing as Hypogammaglobulanemia -- just an easier name to hang on. I've noticed a lot of doctors prefer one over the other -- but it's the same animal as far as I know. Low IgG's or unworking IgG's are what cause the vaccination response to be low. Without the proper IgG's the body can't build an antibody response to germs -- whether they are introduced by vaccination or by encounter in the real world. It's just easier to test something after vaccination -- because you KNOW they have been exposed and should have built a response. So -- when there is a low vaccination response - there will be the same response to that type of germ in everyday life. If I've muddied the question -- please try me again! I'm really glad you are starting IVIG for -- I really think that may help with the mouth sores and all. I certainly hope so. No child should have to suffer like has. Here's a funny wish for you -- I will pray that will drive you crazy for the right reasons in the next few months! What we've found when these kids get healthy is that the parents discover mischieveousness and personality that they've never seen before. I remember being so glad when Katy was able to " fight " me again. She was so passive while she was sick. But she made up for it when she got better!!!!! May God bless you with a fiesty handful! In His service, Dale Quote Link to comment Share on other sites More sharing options...
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