Re: OT/ cancer tonic

[Guest guest]

OT/ cancer tonic

> Hi OM, from danishmom416

> Hi, I was reading your file on the cancer tonic and it has an

> ingredient that is found to cause liver damage . you may want to make a

> note about( Chaparral).Thank you , nne

>

>

> Has anyone on this site tried this tonic? I was thinking of doing some

> spring cleaning.

> thanks nne

nne...the link below gives the other side of the story, and asserts any

evidence of the toxicity claim as anecdotal, ie no blind studies, etc.

Once again the final responsibility is on the individual to research both

sides of a controversial subject and make their own best made decision.

http://curezone.com/forums/fm.asp?i=1058931

Gayle

[Guest guest]

OT/ cancer tonic

> Hi OM, from danishmom416

> Hi, I was reading your file on the cancer tonic and it has an

> ingredient that is found to cause liver damage . you may want to make a

> note about( Chaparral).Thank you , nne

>

>

> Has anyone on this site tried this tonic? I was thinking of doing some

> spring cleaning.

> thanks nne

nne...the link below gives the other side of the story, and asserts any

evidence of the toxicity claim as anecdotal, ie no blind studies, etc.

Once again the final responsibility is on the individual to research both

sides of a controversial subject and make their own best made decision.

http://curezone.com/forums/fm.asp?i=1058931

Gayle

[Guest guest]

Dr Shultz is a master herbalist and uses chaparral extensively for

cancer. I find it

ironic that the Fed Forest surrounding CA are covered in Chaparral and they

won't let us

harvest it, YET it burns out of control and causes huge destruction to the

neighboring

communities. Thanks for that link to curezone! Great info.

Diane

http://peacefulacres.wordpress.com

>

>

> OT/ cancer tonic

>

>

> > Hi OM, from danishmom416

> > Hi, I was reading your file on the cancer tonic and it has an

> > ingredient that is found to cause liver damage . you may want to make a

> > note about( Chaparral).Thank you , nne

> >

> >

> > Has anyone on this site tried this tonic? I was thinking of doing some

> > spring cleaning.

> > thanks nne

>

> nne...the link below gives the other side of the story, and asserts any

> evidence of the toxicity claim as anecdotal, ie no blind studies, etc.

> Once again the final responsibility is on the individual to research both

> sides of a controversial subject and make their own best made decision.

>

> http://curezone.com/forums/fm.asp?i=1058931

>

> Gayle

>

[Guest guest]

>

> Hi OM, from danishmom416

> Hi, I was reading your file on the cancer tonic and it has an

> ingredient that is found to cause liver damage . you may want to make a

> note about( Chaparral).Thank you , nne

>

>

> Has anyone on this site tried this tonic? I was thinking of doing some

> spring cleaning.

> thanks nne

Actually, the injury method (cholestasis: suppression of bile flow,

resulting in extreme cases in jaundice) is known. Often this

cholestasis is reversible upon cessation of chaparral consumption, but

often it is not.

It's important to realize that herbal remedies are no more or less

drugs than conventional pharmaceutical agents: they're merely

less-understood. Here's a sampling of results that show up for a quick

PubMed search on the topic (with links).

Kauma H, et al, " Toxic acute hepatitis and hepatic fibrosis after

consumption of chaparral tablets. " Scand J Gastroenterol. 2004

Nov;39(11):1168-71.

In this report we describe a young, previously healthy woman who

developed severe acute hepatitis after consumption of chaparral

tablets, a commonly used herbal product. In this case, the

elimination-rechallenge event and the exclusion of other possible

aetiologic factors strongly supported true causality between the

herbal product and the liver damage. Primary liver biopsy showed

severe toxic hepatitis consistent with previous reports of

chaparral-induced liver damage. Later, 6 months after the liver

function tests had normalized, permanent hepatic fibrosis could still

be seen.

http://tinyurl.com/28duk2

Stickel F, et al, " [Liver toxicity of drugs of plant origin]. " Z

Gastroenterol. 2001 Mar;39(3):225-32, 234-7.

Herbal drugs are widely used and often contain highly active

pharmacological compounds. Recently, reports have mounted about

hepatotoxicity of herbal remedies which ranges from mild liver enzyme

alterations to chronic liver disease and liver failure. Hepatotoxicity

of Chinese herbs has been recognized, e.g. during treatment of

patients with atopic eczema. However, the toxic compounds remain to be

determined. Hepatic veno-occlusive disease may result from

pyrrolizidine alkaloids which are contained in numerous plants

worldwide. Teucrium chamaedrys, commonly referred to as germander, may

cause hepatitis and even liver cirrhosis. Significant hepatotoxicity

has also been observed after the ingestion of chaparral. Recently,

greater celandine, which is widely used for biliary disorders and

dyspepsia, was identified as a cause of cholestatic hepatitis.

Hepatotoxic reactions have also been observed after the ingestion of

Atractylis gummifera, Callilepsis laureola, Senna, Kavapyrone and

Pulegium. The aim of this review is to summarize potentially

hepatotoxic herbal remedies, to further elucidate their mechanisms of

toxicity and thereby underline the likelihood of plants to be the

cause of liver damage.

http://tinyurl.com/36ab76

Sheikh NM, et al, " Chaparral-associated hepatotoxicity. " Arch Intern

Med. 1997 Apr 28;157(8):913-9.

BACKGROUND: Personal health care practices that may include the use of

dietary supplements are common in the United States. Products marketed

as dietary supplements are diverse and may include botanicals,

vitamins, and/or minerals. Chaparral (Larrea tridentata) is a

botanical dietary supplement made from a desert shrub and used for its

antioxidant properties. Several reports of chaparral-associated

hepatitis have been published since 1990, but a complete picture of

the clinical presentation is still unclear. MATERIALS AND METHODS: We

reviewed the 18 case reports of adverse events associated with the

ingestion of chaparral reported to the Food and Drug Administration

between 1992 and 1994. These reports were from health care

professionals, state health departments, and individual consumers.

RESULTS: Of 18 reports of illnesses associated with the ingestion of

chaparral, there was evidence of hepatotoxicity in 13 cases. Clinical

presentation, characterized as jaundice with a marked increase in

serum liver chemistry values, occurred 3 to 52 weeks after the

ingestion of chaparral, and it resolved 1 to 17 weeks after most

individuals stopped their intake of chaparral. The predominant pattern

of liver injury was characterized as toxic or drug-induced cholestatic

hepatitis; in 4 individuals, there was progression to cirrhosis; and

in 2 individuals, there was acute fulminant liver failure that

required liver transplants. CONCLUSIONS: These data indicate that the

use of chaparral may be associated with acute to chronic irreversible

liver damage with fulminant hepatic failure, and they underscore the

potential for certain dietary supplement ingredients to cause toxic

effects on the liver. Health professionals should be encouraged to

inquire routinely about the use of dietary supplements and other

products, to be alert to potential adverse effects that may be

associated with these products, and, finally, to report any serious

adverse events associated with these products through the MEDWatch

Program of the Food and Drug Administration.

http://tinyurl.com/2gzx25

Batchelor WB, et al, " Chaparral-induced hepatic injury. " Am J

Gastroenterol. 1995 May;90(5):831-3.

Two patients with hepatic injury after ingestion of chaparral leaf are

presented. The first patient, a 71-yr-old man, developed biopsy-proven

hepatitis 3 months after ingesting chaparral leaf daily. His illness

resolved with discontinuation of the herb and later recurred with

rechallenge. The second patient is a 42-yr-old woman who developed

hepatitis 2 months after chaparral leaf ingestion and recovered

completely after discontinuation of the compound. Both patients have

remained well with abstinence from chaparral. These reports provide

evidence of the hepatotoxicity of this herb and stress the need for

awareness of the potential harm from such nonprescription remedies.

http://tinyurl.com/2tc2r3

Gordon DW, et al, " Chaparral ingestion. The broadening spectrum of

liver injury caused by herbal medications. " JAMA. 1995 Feb

8;273(6):489-90.Links

Unconventional medical practices, including the use of herbal

remedies, are prevalent in the United States. Chaparral is an herbal

preparation made from a desert shrub and used for its antioxidant

properties. We report the case of a 60-year-old woman who took

chaparral for 10 months and developed severe hepatitis for which no

other cause could be found. Despite aggressive supportive therapy, the

patient deteriorated and required orthotopic liver transplantation.

She is now well, more than 1 year after her transplant. This case

suggests that chaparral can cause serious liver injury and fulminant

hepatic failure. Herbal medications should be considered as potential

causes of liver toxicity.

http://tinyurl.com/28y5bg

Alderman S, et al, " Cholestatic hepatitis after ingestion of chaparral

leaf: confirmation by endoscopic retrograde cholangiopancreatography

and liver biopsy. " J Clin Gastroenterol. 1994 Oct;19(3):242-7.

The use of herbal and other " natural " health products by healthy and

ill people is more common than is appreciated by many health care

providers. Since most of these substances are not categorized as

medicines, they are exempt from U.S. Government approval processes,

and are essentially uncontrolled. In this article we describe a

patient who developed painless jaundice, fatigue, and pruritus after

taking chaparral tablets, 160 mg/day, for approximately 2 months.

Serial liver biopsies and serum chemistries documented severe

cholestasis and hepatocellular injury, i.e., a severe cholangiolitic

hepatitis. Serum enzyme levels were markedly elevated: alk. phos. to

four-fold, alanine aminotransferase and aspartate aminotransferase to

25-fold, total bilirubin to 30-fold, and gamma-glutamyl transpeptidase

to 35-fold. Endoscopic retrograde cholangiopancreatography showed

smooth, but severely narrowed biliary ducts without sclerosing

cholangitis, distal obstruction, tumor, or stenosis. The diagnosis

remained in doubt until the publication of two cases of chaparral

hepatotoxicity. Because of the similarity of our patient's illness to

those cases we concluded that chaparral was almost certainly the

cause. Chaparral, also known as creosote or greasewood, is used by

some practitioners to treat a diverse group of ailments including

ethanol withdrawal. This report should heighten the awareness by

primary care physicians and gastroenterologists that any chaparral

herbal preparation is a potential hepatotoxin that can lead to serious

illness.

http://tinyurl.com/2ubu2x

Katz M, et al, " Herbal hepatitis: subacute hepatic necrosis secondary

to chaparral leaf. "

A 33-year-old woman developed subacute hepatic necrosis after several

months of ingestion of Chaparral Leaf, an herbal product. Symptoms

first appeared 3 months after she began taking the tablets. The

patient unwittingly carried out a clinical challenge by reducing, then

increasing, the dose of pills. The public and the medical profession

must be wary of all " harmless " nonprescription medications, whether

purchased in pharmacies or elsewhere.

http://tinyurl.com/yulagt

[Guest guest]

Thanks for all the info everyone. I'm gonna make the tonic without

the chaparral or poke root. Just a little spring cleaning.

best wishes, nne

> >

> > Hi OM, from danishmom416

> > Hi, I was reading your file on the cancer tonic and it has an

> > ingredient that is found to cause liver damage . you may want to

make a

> > note about( Chaparral).Thank you , nne

> >

> >

> > Has anyone on this site tried this tonic? I was thinking of doing

some

> > spring cleaning.

> > thanks nne

> >

>

[Guest guest]

> Thanks for all the info everyone. I'm gonna make the tonic without

> the chaparral or poke root. Just a little spring cleaning.

I'm glad you're not using the toxic ingredients. Good for you for

checking it out ahead of time! This just goes to show that " natural "

doesn't necessarily equate with " innocuous " .

[Guest guest]

I finished a small batch of the tonic and it is very palatable. The

licorice root dominates the other herbs. I hope this does the trick. I

have 20 years of pesticides in my system.I used to spray a greenhouse

full of plants. I hate to think whats in my body. (My bigone days of

idiocy). Now I know better.

Heres to good health, nne

[Guest guest]

nne, cilantro is good for pulling toxic metals out of your system too.

Make a salsa with loads of cilantro, add it to salad, etc. KT for the

vinegar in the salad dressing - the best of both worlds.

Gayla

Always Enough Ranch

Acampo, California

aeranch@...

Re: OT/ cancer tonic

>I finished a small batch of the tonic and it is very palatable. The

> licorice root dominates the other herbs. I hope this does the trick. I

[Guest guest]

I would be ever so greatful for this recipe...I looked at files section and

cannot really make out wjat is what...Thnx...ron in leander tx

In a message dated 3/10/2008 10:16:40 A.M. Central Standard Time,

sehrgut@... writes:

> Thanks for all the info everyone. I'm gonna make the tonic without

> the chaparral or poke root. Just a little spring cleaning.

I'm glad you're not using the toxic ingredients. Good for you for

checking it out ahead of time! This just goes to show that " natural "

doesn't necessarily equate with " innocuous " .

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