Liver Enzyme Systems and Drug Intolerance and Interactions

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A while back I mentioned in a post a reference to Dr. Ray Strand's book, Death by Prescription, in which he describes the dangers of taking two or more drugs that utilize the same liver enzyme system for metabolization. One problem is that not everyone's enzyme systems have the same capacity for metabolizing drugs, and another is that when two or more drugs require the same system, there is the potential for overload, which equals overdose. I wanted to include in my post Dr. Strand's list of the drugs that use the same system as statins, but at the time I realized I'd lent the book to someone and my statin-addled brain could not remember who. Hurray, my friend who's had it all along, had forgotten that she had not returned it, but when she ran across it this week, she brought it back to me.One thing

that was of particular interest to me was that this Cytochrome P450 System, which breaks down statins, is also necessary for the metabolization of several other drugs that I have never been able to tolerate: Codeine, Naproxen, and Prednisone. Another on this list is Ambien, which I have taken exactly once, and I experienced the infamous Ambien amnesia, which is supposedly extremely rare. Never again would I take a dose of any of them. Obviously, I have a deficiency in this enzyme system, but the doctor who put me on the extremely toxic dose of Lipitor for two years never checked my liver enzymes even once.See attachment for Dr. Strand's list. ----- Fight back spam! Download the Blue Frog. http://www.bluesecurity.com/register/s?user=bmFuY2FybDIwNzQ%3D