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Re: Heads up! ~ Drug combo works well for diabetes and high lipids

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are you saying to USE statins? caroline

Heads up! ~ Drug combo works well for diabetes and high lipids

Be on the ALERT if you are diabetic... ~ Zocor plus Tricor double punch!Fran

Drug combo works well for diabetes and high lipids

URL of this page: http://www.nlm.nih.gov/medlineplus/news/fullstory_36607.html (*this news item will not be available after 08/26/2006)

Thursday, July 27, 2006

By

NEW YORK (Reuters Health) - For people with diabetes who also have abnormal levels of blood fats, or lipids, the combination of two types of cholesterol-lowering drugs seems to work better than either one alone, researchers report.

People with diabetes typically tend to have mixed lipid abnormalities, such as high cholesterol and high triglycerides. "Much of the cardiovascular risk associated with diabetes may stem from the associated abnormal 'diabetic' lipid profile, Dr. ph B. Muhlestein told Reuters Health.

This profile, which is characterized by a combination of abnormal lipid parameters, cannot often be rectified by just one drug," he explained.

Muhlestein, at the LDS Hospital in Salt Lake City, Utah, and his colleagues therefore looked at using a combination of simvastatin (better known as Zocor) and fenofibrate (Tricor is one example) for such patients.

As described in the Journal of the American College of Cardiology, the team randomly allocated 300 patients with type 2 diabetes and mixed lipid abnormalities but no history of heart disease, to daily treatment with simvastatin, fenofibrate, or to both of these agents.

After 12 weeks, the researchers found that combination therapy was superior to fenofibrate alone in reducing total cholesterol and LDL ("bad") cholesterol. Compared to simvastatin alone, it was superior in reducing triglyceride levels.

"Like in patients with high blood pressure, a multi-drug therapy approach may be necessary," Muhlestein concluded. He said the study shows that "the combination of a statin and a fibrate is safe and more effective than monotherapy in improving the ... lipid profile of diabetic patients."

SOURCE: Journal of the American College of Cardiology, July 18, 2006

Date last updated: 28 July 2006

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are you saying to USE statins? caroline

Heads up! ~ Drug combo works well for diabetes and high lipids

Be on the ALERT if you are diabetic... ~ Zocor plus Tricor double punch!Fran

Drug combo works well for diabetes and high lipids

URL of this page: http://www.nlm.nih.gov/medlineplus/news/fullstory_36607.html (*this news item will not be available after 08/26/2006)

Thursday, July 27, 2006

By

NEW YORK (Reuters Health) - For people with diabetes who also have abnormal levels of blood fats, or lipids, the combination of two types of cholesterol-lowering drugs seems to work better than either one alone, researchers report.

People with diabetes typically tend to have mixed lipid abnormalities, such as high cholesterol and high triglycerides. "Much of the cardiovascular risk associated with diabetes may stem from the associated abnormal 'diabetic' lipid profile, Dr. ph B. Muhlestein told Reuters Health.

This profile, which is characterized by a combination of abnormal lipid parameters, cannot often be rectified by just one drug," he explained.

Muhlestein, at the LDS Hospital in Salt Lake City, Utah, and his colleagues therefore looked at using a combination of simvastatin (better known as Zocor) and fenofibrate (Tricor is one example) for such patients.

As described in the Journal of the American College of Cardiology, the team randomly allocated 300 patients with type 2 diabetes and mixed lipid abnormalities but no history of heart disease, to daily treatment with simvastatin, fenofibrate, or to both of these agents.

After 12 weeks, the researchers found that combination therapy was superior to fenofibrate alone in reducing total cholesterol and LDL ("bad") cholesterol. Compared to simvastatin alone, it was superior in reducing triglyceride levels.

"Like in patients with high blood pressure, a multi-drug therapy approach may be necessary," Muhlestein concluded. He said the study shows that "the combination of a statin and a fibrate is safe and more effective than monotherapy in improving the ... lipid profile of diabetic patients."

SOURCE: Journal of the American College of Cardiology, July 18, 2006

Date last updated: 28 July 2006

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We all know that it is probable that the drugs do lower lipid levels.

What it assumes is that will translate into lower heart disease rates

and lower mortality rates. So far, the actual evidence is

thatartificially lower cholesterol rates do not have any correlation

with mortality--in fact, they are slightly higher.

Linden

Re: Heads up! ~ Drug combo works well

for diabetes and high lipids

are you saying to USE statins? caroline

Heads up! ~ Drug combo works well

for diabetes and high lipids

Be on the ALERT if you are diabetic...

~ Zocor plus Tricor double punch!

Fran

--------

Drug combo works well for diabetes and high lipids URL of this page:

http://www.nlm.nih.gov/medlineplus/news/fullstory_36607.html

(*this news item will not be available after 08/26/2006)

[image removed]

Thursday, July 27, 2006

By

NEW YORK (Reuters Health) - For people with diabetes who also have

abnormal levels of blood fats, or lipids, the combination of two types

of cholesterol-lowering drugs seems to work better than either one

alone, researchers report.

People with diabetes typically tend to have mixed lipid abnormalities,

such as high cholesterol and high triglycerides. " Much of the

cardiovascular risk associated with diabetes may stem from the

associated abnormal 'diabetic' lipid profile, Dr. ph B. Muhlestein

told Reuters Health.

This profile, which is characterized by a combination of abnormal

lipid parameters, cannot often be rectified by just one drug, " he

explained.

Muhlestein, at the LDS Hospital in Salt Lake City, Utah, and his

colleagues therefore looked at using a combination of simvastatin

(better known as Zocor) and fenofibrate (Tricor is one example) for

such patients.

As described in the Journal of the American College of Cardiology, the

team randomly allocated 300 patients with type 2 diabetes and mixed

lipid abnormalities but no history of heart disease, to daily treatment

with simvastatin, fenofibrate, or to both of these agents.

After 12 weeks, the researchers found that combination therapy was

superior to fenofibrate alone in reducing total cholesterol and LDL

( " bad " ) cholesterol. Compared to simvastatin alone, it was superior in

reducing triglyceride levels.

" Like in patients with high blood pressure, a multi-drug therapy

approach may be necessary, " Muhlestein concluded. He said the study

shows that " the combination of a statin and a fibrate is safe and more

effective than monotherapy in improving the ... lipid profile of

diabetic patients. "

SOURCE: Journal of the American College of Cardiology, July 18, 2006

Date last updated: 28 July 2006

--------

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Guest guest

We all know that it is probable that the drugs do lower lipid levels.

What it assumes is that will translate into lower heart disease rates

and lower mortality rates. So far, the actual evidence is

thatartificially lower cholesterol rates do not have any correlation

with mortality--in fact, they are slightly higher.

Linden

Re: Heads up! ~ Drug combo works well

for diabetes and high lipids

are you saying to USE statins? caroline

Heads up! ~ Drug combo works well

for diabetes and high lipids

Be on the ALERT if you are diabetic...

~ Zocor plus Tricor double punch!

Fran

--------

Drug combo works well for diabetes and high lipids URL of this page:

http://www.nlm.nih.gov/medlineplus/news/fullstory_36607.html

(*this news item will not be available after 08/26/2006)

[image removed]

Thursday, July 27, 2006

By

NEW YORK (Reuters Health) - For people with diabetes who also have

abnormal levels of blood fats, or lipids, the combination of two types

of cholesterol-lowering drugs seems to work better than either one

alone, researchers report.

People with diabetes typically tend to have mixed lipid abnormalities,

such as high cholesterol and high triglycerides. " Much of the

cardiovascular risk associated with diabetes may stem from the

associated abnormal 'diabetic' lipid profile, Dr. ph B. Muhlestein

told Reuters Health.

This profile, which is characterized by a combination of abnormal

lipid parameters, cannot often be rectified by just one drug, " he

explained.

Muhlestein, at the LDS Hospital in Salt Lake City, Utah, and his

colleagues therefore looked at using a combination of simvastatin

(better known as Zocor) and fenofibrate (Tricor is one example) for

such patients.

As described in the Journal of the American College of Cardiology, the

team randomly allocated 300 patients with type 2 diabetes and mixed

lipid abnormalities but no history of heart disease, to daily treatment

with simvastatin, fenofibrate, or to both of these agents.

After 12 weeks, the researchers found that combination therapy was

superior to fenofibrate alone in reducing total cholesterol and LDL

( " bad " ) cholesterol. Compared to simvastatin alone, it was superior in

reducing triglyceride levels.

" Like in patients with high blood pressure, a multi-drug therapy

approach may be necessary, " Muhlestein concluded. He said the study

shows that " the combination of a statin and a fibrate is safe and more

effective than monotherapy in improving the ... lipid profile of

diabetic patients. "

SOURCE: Journal of the American College of Cardiology, July 18, 2006

Date last updated: 28 July 2006

--------

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NO Caroline... Just trying to alert members that if they are diabetic,

their doctor is most likely going to recommend Zocor and Tricor,

even if their cholesterol levels are normal, based solely on the fact

that they are diabetic.

Sorry I didn't add that info before the article to explain my "Alert".

Fran

Heads up! ~ Drug combo works well for diabetes and high lipids

Be on the ALERT if you are diabetic... ~ Zocor plus Tricor double punch!Fran

Drug combo works well for diabetes and high lipids

URL of this page: http://www.nlm.nih.gov/medlineplus/news/fullstory_36607.html

..

Link to comment
Share on other sites

Guest guest

NO Caroline... Just trying to alert members that if they are diabetic,

their doctor is most likely going to recommend Zocor and Tricor,

even if their cholesterol levels are normal, based solely on the fact

that they are diabetic.

Sorry I didn't add that info before the article to explain my "Alert".

Fran

Heads up! ~ Drug combo works well for diabetes and high lipids

Be on the ALERT if you are diabetic... ~ Zocor plus Tricor double punch!Fran

Drug combo works well for diabetes and high lipids

URL of this page: http://www.nlm.nih.gov/medlineplus/news/fullstory_36607.html

..

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Share on other sites

Guest guest

thanks fran.. I am a diabetic..and I will not take any statins.. my friends and family think I am crazy.. caroline

Heads up! ~ Drug combo works well for diabetes and high lipids

Be on the ALERT if you are diabetic... ~ Zocor plus Tricor double punch!Fran

Drug combo works well for diabetes and high lipids

URL of this page: http://www.nlm.nih.gov/medlineplus/news/fullstory_36607.html

..

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Share on other sites

Guest guest

thanks fran.. I am a diabetic..and I will not take any statins.. my friends and family think I am crazy.. caroline

Heads up! ~ Drug combo works well for diabetes and high lipids

Be on the ALERT if you are diabetic... ~ Zocor plus Tricor double punch!Fran

Drug combo works well for diabetes and high lipids

URL of this page: http://www.nlm.nih.gov/medlineplus/news/fullstory_36607.html

..

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Caroline....get your friends and family on this group and

have them read all about the wonder drug that is supposed

to cure everything from cancer to hiccups...statins!!!

What a ingenious method of marketing to a nieve society of

sheep. " If it is on TV it must be true. " " Oh...it is

approved by the FDA, it is perfectly safe for me to take. "

Yeah right!!!!!

Ed

>

> thanks fran.. I am a diabetic..and I will not take any statins.. my

friends and family think I am crazy.. caroline

> Heads up! ~ Drug combo works

well for diabetes and high lipids

>

>

>

> Be on the ALERT if you are diabetic...

> ~ Zocor plus Tricor double punch!

> Fran

>

>

--------------------------------------------------------------------------

>

> Drug combo works well for diabetes and high lipids

> URL of this page:

http://www.nlm.nih.gov/medlineplus/news/fullstory_36607.html

>

> .

>

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