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Re: Re: Zetia???

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RWA000@... wrote:

>

>

> phine- do you always talk out of both sides of your mouth, you can't

> site studies to prove your point then compltely blow off studies that

> the drug companies have done to show statins lower cholesterol.Try being

> a little less militant or people will not take you seriously.

Studies are biased by:

Profit motive.

Agendas.

Financing.

Study objectives.

Study construction.

Etc.

Not all studies are created equal and studies can be constructed to reach

desired outcomes and hide undesired outcomes. Even independant studies

conducted by educational establishments are skewed by grant sources and future

employment opportunities of the researches or past employers, peer pressure to

toe the line to the current medical mantras, etc.

Fundamentally I find compelling reasons to seek out better constructed studies

and weight them more heavily and to take poorly constructed studies or studies

with larger potential for bias and to weight them less heavily. While I don't

remember phine's message (and you didn't include even a portion of it you

were replying to) she is certainly rational to make reasoned judgments about the

merits of any study as she so chooses. We both might disagree, but lets us

disagree on the merits.

Personally, drug company studies ALL come with " strings " attached and one should

be careful. As to the merits of lowering cholesterol, that is another big

question all by itself. Starting from a total cholesterol of 300 and moving

towards lower, all cause mortality increases regardless of what the drug

companies have to say about cardiovascular events in particular. As you lower

your cholesterol, your chances of dying increases and this mortality profile

dramatically increases deaths from all causes as it drops down past 180. One

may be marginally less likely to die from a cardiovascular event, but one will

be more likely to die from other causes CAUSED by the lowering of cholesterol.

As to Zetia, I took it on two separate occasions. It lowered my total

cholesterol about 20 points of which 50% was HDL, the " good " cholesterol. The

result was that my HDL ratio got worse.

--

Steve - dudescholar4@...

Take World's Smallest Political Quiz at

http://www.theadvocates.org/quiz.html

" If a thousand old beliefs were ruined on our march

to truth we must still march on. " --Stopford

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